Clinical trials: Lumbar Radicular Pain
Lumbosacral Radicular Pain, Lumbar Radiculopathy
Determination of Sensitivity and Specificity of Straight Leg Raise Test Via Transforaminal Nerve Root Block
This study aims to evaluate the diagnostic accuracy of the straight leg raise test in patients with suspected lumbosacral radicular pain.
- Conditions
- Lumbosacral Radicular Pain, Lumbar Radiculopathy, Straight Leg Raise
- Trial name
- NCT07696312
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people
- Sponsor
- Marmara University
Lumbar Disc Herniation
Effectiveness of PEMF in Patients With Chronic Radicular Pain Due to Lomber Disc Herniation
The aim of this study is to investigate the effectiveness of pulse magnetic field therapy on pain, functional status, and quality of life in patients with chronic radicular pain due to lumbar disc herniation.
- Trial name
- NCT04049812
- Testing
- PEMF, Hot pack, TENS
- Volunteers
- 50 people
- Sponsor
- Birkan Sonel Tur
Lumbar Radiculopathy
Safety and Efficacy of SX600 Administered by Lumbosacral Transforaminal Epidural Injection for Radicular Pain
This is a Phase I/II, double-blind, parallel-group, randomized, placebo-controlled multi-centre trial in 180 patients randomized 1:1:1 to receive the IMP (Dexamethasone acetate microspheres for extended-release injectable…
- Trial name
- SALIENT (NCT03952377)
- Testing
- SX600
- Where
- 10 sites in Australia
- Volunteers
- 56 people
- Sponsor
- SpineThera Australia PTY LTD
Chronic Pain
Trans-foraminal Lumbar Epidural Injection of Dexmedetomidine Against Magnesium Sulfate When Combined With Dexamethasone in Uni-lateral Lower Limb Radicular Pain. Multi-centeric Comparative Study
Transforaminal injection of chronic radicular lower limb injection by either dexmedetomdine or magnesuim sulfate
- Trial name
- NCT05271721
- Testing
- epidural transforaminal injection of magnesuim sulfate, epidural transforaminal injection of dexmedtemodine, transforaminal epidural injection of dexamethasone
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Minia University
Radicular; Neuropathic, Lumbar, Lumbosacral, Radicular; Neuropathic, Cervical
Comparison of Gabapentin and Pregabalin for Radicular Pain
Although some studies show improvement of pain and associated effects of pain with off-label use of neuropathic agents for cervical or lumbar radiculopathy, there is limited published evidence so far.
- Trial name
- NCT02064790
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Emory University
Lumbar Disc Herniation, Radiculopathy
Application of 3D Printing Guide Plate in Percutaneous Disc Decompression
Application of 3D printing guide plate in percutaneous disc decompression
- Conditions
- Lumbar Disc Herniation, Radiculopathy, Percutaneous Disc Decompression, 3D Printing Guide Plate
- Trial name
- NCT05610553
- Testing
- 3D printing guide plate, Conventional guidance
- Where
- China
- Volunteers
- 32 people
- Sponsor
- Peking University Third Hospital
Lumbar Disc Herniation, Radiculopathy Lumbar
Comparison of the Effectiveness of Erector Spina Plane Block and Transforaminal Anterior Epidural Injections
Low back pain is one of the leading causes of disability and its social burden and economic cost are quite high. The lifetime prevalence in the population is frequently reported between 40% and 70%.
- Trial name
- NCT05719792
- Testing
- Transforaminal Epidural Steroid Injection, Erector Spina Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Marmara University
Lumbar Radiculopathy, Pain, Intractable
Radiocontrast Media in the Pulsed Radiofrequency Treatment
Pulsed radiofrequency applied to the dorsal root ganglion (DRG) is an interventional treatment alternative in the treatment of lumbar radicular pain that does not respond to conservative methods.
- Trial name
- NCT04876469
- Testing
- Pulsed Radiofrequency treatment of the lumbar dorsal root ganglion
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Sanliurfa Education and Research Hospital
Lumbar Radicular Pain, Spinal
Cutaneous Silent Period-Based Comparison of DRG-PRF and TFESI in Lumbar Radicular Pain
This prospective clinical study compares the effects of two interventional treatments, dorsal root ganglion pulsed radiofrequency (DRG-PRF) and transforaminal epidural steroid injection (TFESI), on patients with lumbar radicular…
- Conditions
- Lumbar Radicular Pain, Spinal, Inhibition
- Trial name
- CSP-LRP (NCT07097532)
- Testing
- Radiofrequency, Transforaminal Epidural Steroid Injection
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- ahmet başarı
Effect of Drug
Comparative Effect of Transforaminal Injection of Magnesium Sulphate Versus Ozone Therapy on Oxidative Stress Biomarkers in Lumbar Disc Related Radicular Pain
Chronic lumbar radicular (CLR) pain is a term used to describe neuropathic pain symptoms in the distribution of a particular lumbar nerve root due to disc protrusion, spinal stenosis, facet hypertrophy, or fibrosis after previous…
- Trial name
- NCT04562493
- Testing
- Transforaminal Epidural injection
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Beni-Suef University
Radiculopathy, Lumbosacral Region, Radiculopathy Lumbar
The Effect of High-power Laser Therapy on Pain, Functional Disability, Range of Motion and Pressure Pain Threshold in Subjects With Radicular Low Back Pain Due to Intervertebral Disc Herniation
Low back pain is the predominant cause of disability on a global scale. In the year 2015, the worldwide point prevalence of activity-limiting low back pain stood at 7·3%, suggesting that at any given moment, 540 million…
- Trial name
- NCT06151704
- Testing
- High intensity laser therapy, Motor control exercise
- Where
- Iran
- Volunteers
- 36 people
- Sponsor
- Iran University of Medical Sciences
Failed Back Surgery Syndrome, Lumbar Radiculopathy
EuroPainClinicsStudy IX ( EPCS IX )
This prospective investigator-initiated study compares the clinical effectiveness and safety of epiduroscopic adhesiolysis in patients with failed back surgery syndrome (FBSS) and in patients with lumbar radicular pain without…
- Conditions
- Failed Back Surgery Syndrome, Lumbar Radiculopathy, Chronic Low Back Pain, Epidural Fibrosis
- Trial name
- EPCS IX (NCT07411950)
- Testing
- Epiduroscopic mechanical adhesiolysis, Epidural pharmacologic therapy
- Where
- Slovakia
- Volunteers
- 141 people
- Sponsor
- EPC Education s.r.o.
Lumbosacral Radiculopathy
US vs FL-Guided Lumbar Nerve Root Injections
The goal of this clinical trial is to learn if ultrasound-guided nerve root injections work as well as fluoroscopy (X-ray)-guided injections to treat lower back and leg pain caused by irritated nerves (lumbosacral radiculopathy)…
- Trial name
- NCT07627308
- Testing
- Ultrasound-Guided Selective Lumbar Nerve Root Injection, Fluoroscopy-Guided Selective Lumbar Nerve Root Injection
- Where
- Egypt
- Volunteers
- 64 people
- Sponsor
- Tanta University
Herniated Disc
Nucleoplasty for Contained Herniated Lumbar Discs
This is a prospective randomised double blind comparison trial. Fifty patients will be included, 25 in the nucleoplasty treatment group, 25 in the control group. The nucleoplasty group will undergo the nucleoplasty treatment.
- Trial name
- NCT00124774
- Testing
- Nucleoplasty
- Where
- Netherlands
- Volunteers
- 50 people
- Sponsor
- Rijnstate Hospital
Inflammatory Response, Radiculopathy
Inflammatory Markers in Lumbar Radicular Pain Treated With PRF and TFESI
This retrospective observational study aims to evaluate the predictive value of systemic inflammatory markers in determining treatment response in patients with lumbar radicular pain treated with a combination of pulsed…
- Conditions
- Inflammatory Response, Radiculopathy, Radiculopathy Lumbar, Chronic Pain
- Trial name
- NCT07495566
- Testing
- Lumbar Dorsal Root Ganglion Pulsed Radiofrequency
- Where
- Turkey (Türkiye)
- Volunteers
- 264 people
- Sponsor
- Ankara Etlik City Hospital
Back Pain With Radiation, Pain, Postoperative
Burst Crossover Trial
Spinal cord stimulation (SCS) is a widely applied therapy to treat chronic neuropathic pain, and one of the most common indications is persisting radicular neuropathic pain following lumbar spine surgery.
- Trial name
- NCT05372822
- Testing
- Burst Spinal Cord Stimulation, SCS implant
- Where
- Norway
- Volunteers
- 40 people
- Sponsor
- St. Olavs Hospital
Lumbar Disc Herniation, Lumbar Radiculopathy
The Role of Temporal Changes in Pain Response After Transforaminal Epidural Steroid Injection on Treatment Success
Transforaminal epidural steroid injection (TFESI) is a commonly used minimally invasive procedure for the treatment of lumbar radicular pain secondary to disc herniation.
- Conditions
- Lumbar Disc Herniation, Lumbar Radiculopathy, Radicular Low Back Pain, Sciatica
- Trial name
- NCT07367191
- Testing
- Transforaminal epidural steroid injection
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Marmara University
Lumbar Disc Herniation With Radiculopathy, Low Back Pain (LBP)
"Effectiveness of Physical Therapy Added to Transforaminal Injection in Lumbar Radicular Pain"
The purpose of this study is to investigate whether adding conventional physical therapy modalities to transforaminal epidural steroid injection (TFESE) provides additional benefits in patients with acute radicular pain due to…
- Trial name
- NCT07467421
- Testing
- TFESE, TFESE+ CONVENTIONAL PHYSIOTHERAPY
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people
- Sponsor
- Ankara Training and Research Hospital
Radicular; Neuropathic, Lumbar, Lumbosacral, Low Back Pain
Transforaminal Epidural Steroid Injection With Pulsed Radiofrequency for Chronic Lumbosacral Radicular Pain Management
The purpose of this study is to examine the potential changes in levels of pain, quality of life (QoL) and activities of daily living (ADL) observed when transforaminal epidural steroid injection is administered in conjunction…
- Conditions
- Radicular; Neuropathic, Lumbar, Lumbosacral, Low Back Pain, Back Pain With Radiation
- Trial name
- NCT02930057
- Testing
- Celestone, pulsed radiofrequency treatment, Control
- Volunteers
- 120 people
- Sponsor
- Sheba Medical Center
Radicular Pain, Lumbar Surgery
Return to Work After Lumbar Surgery: a Nationwide Survey of Spinal Surgeons' Practices
This national cross-sectional survey investigates the current practices and perceptions of Belgian spinal surgeons regarding return to work (RTW) after lumbar surgery for radicular pain.
- Conditions
- Radicular Pain, Lumbar Surgery, Radicular Pain Related to Lumbosacral Disc Disease, Fusion of Spine, Lumbar Region
- Trial name
- NCT07193758
- Where
- Belgium
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven