Clinical trials: Lumbar Surgery
Constriction, Pathologic, Spine Degeneration
Strategic Use of Big Data in Spine Surgery - Testing Digital Prediction of Outcome in Clinical Praxis
The goal of this prospective, multicenter clinical trial is to determine if the use of the postoperative outcome prediction model the Dialogue Support tool can alter postoperative patient-reported outcome and satisfaction…
- Conditions
- Constriction, Pathologic, Spine Degeneration, Surgery, Radiculopathy
- Trial name
- NCT05817747
- Testing
- Dialogue support tool
- Where
- 10 sites in Sweden
- Volunteers
- 900 people
- Sponsor
- Sahlgrenska University Hospital
Lumbar Spinal Stenosis
Can Minimally Invasive Decompression Surgery Restore Sagittal Balance in a Patient Population With Sagittal Imbalance and Lumbar Spinal Stenosis
From adulthood onwards, the aging process manifests itself in the spine through loss of disc height and kyphotic deformity. As the general population ages, the prevalence of lumbar degenerative diseases and sagittal imbalance…
- Trial name
- NCT06075355
- Where
- France
- Volunteers
- 116 people
- Sponsor
- Fondation Hôpital Saint-Joseph
Spinal Stenosis
Surgical Versus Nonsurgical Treatment for Spinal Stenosis
Lumbar spinal stenosis (a narrowing of spaces in the backbone that results in pressure on the spinal cord and/or nerve roots) is a condition that occurs frequently, particularly in the elderly.
- Trial name
- NCT00022776
- Testing
- Surgical decompression, Physical therapy
- Where
- United States
- Volunteers
- 178 people
- Sponsor
- University of Pittsburgh
Lumbar Spinal Stenosis, Degenerative Lumbar Spondylolisthesis
Retrospective Comparison of Tubular Decompression ± Rhizotomy Versus TLIF in Lumbar Spinal Stenosis
This retrospective observational study examines clinical outcomes in patients with lumbar spinal stenosis who underwent minimally invasive tubular decompression, with or without subsequent multisegmental percutaneous rhizotomy…
- Conditions
- Lumbar Spinal Stenosis, Degenerative Lumbar Spondylolisthesis, Neurogenic Claudication
- Trial name
- TUBE-FUSE (NCT07489508)
- Where
- 2 sites in Spain
- Volunteers
- 246 people
- Sponsor
- University of Valencia
Lumbar Spinal Stenosis
Minimal Invasive Surgery Versus Interlaminar Decompression in Lumbar Canal Stenosis
Conventional open surgery has been shown to be an effective procedure for LCS decompression. Minimally invasive surgery (MIS) through tubular retractors is a recently introduced alternative procedure for decompression of LCS.
- Trial name
- NCT05147064
- Testing
- minimally invasive surgery, conventional open surgery
- Volunteers
- 40 people
- Sponsor
- Assiut University
Lumbar Disc Surgery
Comparing The Effect of Adding Dexmedetomidine to Bupivacaine in Classical and Modified Thoracolumbar Interfascial Plane Block on Postoperative Pain in Patients Undergoing Lumbar Disc Surgeries
Spinal surgeries are frequently conducted to stabilize the vertebrae and discs of the spine. These surgeries typically require substantial manipulation of subcutaneous tissues, bones, and ligaments .
- Trial name
- NCT06690021
- Testing
- Dexmedetomidine
- Volunteers
- 26 people
- Sponsor
- Assiut University
Anesthesia
The Effect and Mechanism of Respiratory Stimulant Doxapram on Facilitating Emergence
The current study is designed to investigate the difference of plasma orexin A levels between doxapram group and controlled group at emergence time from sevoflurane-remifentanil anesthesia who will undergo elective lumbar surgery.
- Trial name
- NCT02820025
- Testing
- doxapram, saline
- Where
- China
- Volunteers
- 40 people
- Sponsor
- General Hospital of Ningxia Medical University
Scoliosis, Scoliosis; Adolescence
Study Comparing the PathKeeper System for Pedicle Screw Positioning in Spine Surgery With Traditional Care
The goal of this is to evaluate performance of the Pathkeeper Surgical System. The main question[s]it aims to answer are: 1) evaluate pedicle screw position Participants will in compare Experimental arm: PathKeeper System (PKS)…
- Conditions
- Scoliosis, Scoliosis; Adolescence, Scoliosis Kyphosis, Scoliosis Lumbar Region
- Trial name
- PKSforPSP (NCT06554093)
- Testing
- Medical Device - PKS
- Where
- United Kingdom
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Deep Health Ltd.
Spine Surgery
Evaluation of an Enhanced Recovery Protocol After Minimally Invasive Lumbar Surgery.
Prospective longitudinal multicentre observational study carried out on a population of patients undergoing minimally invasive spine surgery and divided into two parallel cohorts according to the presence or absence of a Enhanced…
- Trial name
- ERAMIS (NCT05015036)
- Testing
- ERAS, Minimally invasive surgery
- Where
- France
- Volunteers
- 100 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Postoperative Pain
Erector Spinae Block Versus Local Field Block in Lumbar Spine Surgeries
Major lumbar spine surgeries are associated with significant postoperative pain that may last for days,So In this study, we intend to evaluate if preventive analgesia with a single injection dose of ultrasound guided bilateral…
- Trial name
- NCT05570565
- Testing
- Erector spinae plane block, local field block
- Where
- Egypt
- Volunteers
- 48 people
- Sponsor
- Cairo University
Degenerative Lumbar Spondylolisthesis, Lumbar Degenerative Disease
Comparison of Endoscopic Lumbar Decompression and Minimally Invasive Transforaminal Lumbar Interbody Fusion(MIS-TLIF) for Degenerative Lumbar Spondylolisthesis
Comparing the functional and radiographic outcomes in surgical treatment in failed conservative treatment, single-level low grade degenerative lumbar spondylolisthesis between Minimal Invasive Surgery Transforaminal Lumbar…
- Conditions
- Degenerative Lumbar Spondylolisthesis, Lumbar Degenerative Disease, Lumbar Spinal Stenosis
- Trial name
- MIS-TLIF (NCT06749314)
- Testing
- Lumbar Endoscopic - Unilateral Laminotomy for Bilateral Decompression
- Where
- Thailand
- Volunteers
- 66 people
- Sponsor
- Queen Savang Vadhana Memorial Hospital, Thailand
Lumbar Spinal Canal Stenosis
Irrigation Endoscopic Decompression
To evaluate a new endoscopic technique for lumbar spinal canal decompression.
- Trial name
- NCT02254590
- Testing
- Irrigation Endoscopic Decompressive Laminotomy
- Volunteers
- 104 people
- Sponsor
- Cairo University
Lumbar Spine Injury, Spinal Fusion
Does Prehabilitation Improve Outcomes in Patients Undergoing Complex Spine Fusion Surgery?
A novel prehabilitation method has been implemented at our institution to decrease perioperative outcome complications for frail complex spine fusion surgery patients.
- Conditions
- Lumbar Spine Injury, Spinal Fusion, Frailty, Prehabilitation
- Trial name
- NCT05034341
- Testing
- Multimodal Prehabilitation, Standard Pre-Surgical Clinical Care
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Florida
Posterior Lumbar Spinal Fusion Surgery
Protective Effect of Tranexamic Acid on Shedding of the Endothelial Glycocalyx in Patients Undergoing Spinal Fusion Surgery
The aim of this study was to determine whether the administration of tranexamic acid in patients undergoing lumbar spinal fusion surgery can inhibit damage in endothelial glycocalyx layer.
- Trial name
- NCT03697681
- Testing
- Tranexamic acid, 0.9% NaCl (normal saline)
- Where
- South Korea
- Volunteers
- 128 people
- Sponsor
- Yonsei University
Nursing Care, Patient Education
Comparison Of The Effects Of Different Body Mechanics Education
The study evaluated the comparison of the different patient education methods. The study involved two stages of data collection: one during the preoperative period, the other during the sixth postoperative week.
- Trial name
- NCT03792230
- Testing
- Video, Brochure
- Where
- Turkey (Türkiye)
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi Gulhane Tip Fakultesi
Spine Fusion, Lumbar Disc Herniation
Examination of the Effect of Early Mobilization on Postoperative Recovery, Pain, Quality of Life and Complication Development in Elective Minimally Invasive Spine Surgery
Accelerated Postoperative Recovery (ERAS) is a multidisciplinary approach aimed at facilitating faster and more effective recovery for patients undergoing surgical procedures.
- Conditions
- Spine Fusion, Lumbar Disc Herniation, Cervical Disc Disease
- Trial name
- NCT06102681
- Testing
- intervention group
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people
- Sponsor
- Duzce University
Spondylolisthesis
Vertebral Osteosynthesis in Degenerative Lumbar Stenosis With Spondylolisthesis
Study to evaluate the superiority of the osteosynthesis associated with a decompressive surgery in comparison with a simple decompressive surgery in the treatment of lumbar degenerative stenosis with spondylolisthesis
- Trial name
- CLEOS (NCT00252551)
- Testing
- Osteosynthesis, Simple surgery
- Where
- 9 sites in France
- Volunteers
- 11 people
- Sponsor
- University Hospital, Toulouse
Spinal Stenosis, Lumbar Region, Spondylolisthesis
Evaluation of 3D Machine-vision Image Guided Surgery Spine Navigation
This study assesses clinical outcomes following the use of the MvIGS spine navigation system for treatment of spinal stenosis and degenerative spondylolisthesis of the lumbar spine in adults.
- Trial name
- NCT03968965
- Testing
- 3D MvIGS Spine Navigation, 2D Fluoroscopy
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- 7D Surgical Inc.
Hip Arthroplasty, Postoperative Pain
Comparison of Pericapsular Nerve Group+ Lateral Femoral Cutaneous Nerve Block Versus Lumbar Erector Spinae Plane Block in Hip Arthroplasty Surgery
Hip replacement surgery (partial or total hip arthroplasty) is commonly performed in elderly patients and is associated with significant postoperative pain.
- Conditions
- Hip Arthroplasty, Postoperative Pain, Hip Fractures, Postoperative Delirium (POD)
- Trial name
- NCT07445009
- Testing
- PENG + LFCN Block, PENG + Lumbar ESP Block
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Lumbar Fusion
A Study on the Use of a Brace Following Low Back Surgery
This study evaluated the hypothesis that bracing following lumbar spinal fusion surgery improves functional outcome following surgery
- Trial name
- NCT00620399
- Testing
- lumbar corset
- Where
- United States
- Sponsor
- Sunnybrook Health Sciences Centre