Clinical trials: Lumbar Surgery
Lumbar Spine Degeneration, Economic Problems
Cost-effectiveness Analysis of Robot-assisted Spinal Surgery
With the change of lifestyle and the aging of the population, the prevalence of Lumbar disc herniation (LDH) in my country is increasing year by year, and surgery is one of the main ways to treat LDH.
- Conditions
- Lumbar Spine Degeneration, Economic Problems, Surgery
- Trial name
- NCT05388383
- Testing
- Ti-robot
- Where
- China
- Volunteers
- 600 people
- Sponsor
- Beijing Jishuitan Hospital
Herniated Lumbar Disc
Postoperative Pain and Analgesic Use Following Lumbar Discectomy: A Comparative Study of Endoscopic Surgery and Open Surgery
The lifetime prevalence of lumbosacral radiculopathy is 3 to 5 percent. The most common cause is a lumbar disc herniation. In 10 to 20 percent of patients, medical treatment is insufficient, and surgery is recommended.
- Trial name
- DISCOPAIN (NCT07766031)
- Testing
- Endoscopic surgery, Open surgery
- Where
- France
- Volunteers
- 140 people
- Sponsor
- Saint-Gregoire Private Hospital Center
Anesthesia, Nausea and Vomiting, Postoperative
Effect of Acupuncture on Postoperative Nausea and Vomiting
In this study, the hypothesis that bilateral acupuncture needling at the Neiguan (PC6) point during the intraoperative period, in addition to the 0.15 mg/kg dose of ondansetron (5-HT3 antagonist) frequently used for postoperative…
- Trial name
- NCT06669676
- Testing
- acupuncture, No acupuncture
- Where
- Turkey (Türkiye)
- Volunteers
- 92 people
- Sponsor
- Ankara City Hospital Bilkent
Disk Herniated Lumbar, Physiotherapy
Supervised Physical Therapy Versus Unsupervised Home Exercise After Surgery for Lumbar Disc Herniation
This is a randomized controlled trial evaluation effect of postoperative rehabilitation after surgery for lumbar disc herniation.
- Conditions
- Disk Herniated Lumbar, Physiotherapy, Surgery
- Trial name
- NCT03505918
- Testing
- No referral for rehabilitation
- Where
- Denmark
- Volunteers
- 146 people
- Sponsor
- Spine Centre of Southern Denmark
Lumbar Disc Surgery, Motivational Interviewing
The Effect of Motivational Interviewing on Patients With Lumbar Discectomy
Abstract Objective: The aim of the study was to determine the effect of motivational interviewing about adaptation to body mechanics on the level of disability due to low back pain and quality of life in patients with lumbar…
- Conditions
- Lumbar Disc Surgery, Motivational Interviewing, Nursing Care
- Trial name
- NCT07169955
- Testing
- Motivational Interviewing
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Gazi University
Pain, Postoperative
TAP Block Efficacy After Lumbar Spine Surgery Through Anterior Approach: a Randomized, Placebo-controlled Study
Anterior Lumbar Interbody Fusion (ALIF) as well as Direct Lateral Interbody Fusion (DLIF) are established techniques for lumbar interbody fusion.
- Trial name
- TAP-LIF (NCT02778178)
- Testing
- ropivacaine plus clonidine, ultrasound
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Lille
Surgical Wound, Herniation
Efficacy of a Full-Thickness Placental Allograft in Lumbar Microdiscectomy
To evaluate the efficacy of full thickness placental allograft use in Microdiscectomy application. To evaluate post-microdiscectomy reherniation rate in patients treated with full-thickness placental allografts.
- Trial name
- NCT03536013
- Testing
- Other: Full-thickness placental allograft
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- StimLabs
Lumbar Spinal Canal Stenosis
Irrigation Endoscopic Decompression
To evaluate a new endoscopic technique for lumbar spinal canal decompression.
- Trial name
- NCT02254590
- Testing
- Irrigation Endoscopic Decompressive Laminotomy
- Volunteers
- 104 people
- Sponsor
- Cairo University
Lumbar Disc Herniation, Postoperative Pain
Comparison of TLIP Block and QIP Block for Postoperative Analgesia After Lumbar Spine Surgery
This study compares two regional anesthesia techniques used for pain control after lumbar spine surgery: the classic thoracolumbar interfascial plane (TLIP) block and the quadratus lumborum-iliac plane (QIP) block.
- Trial name
- TLIP-QIP (NCT07750418)
- Testing
- Thoracolumbar Interfascial Plane (TLIP) Block of bupivacaine, Quadratus Lumborum-Iliac Plane (QIP) Block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Vezirköprü State Hospital
Anesthesia
Difference of Plasma Orexin A Levels Between Elderly and Young Patients at Emergence
The current study is designed to investigate the difference of plasma orexin A levels between elderly and young patients at emergence from sevoflurane-fentanyl anesthesia who will undergo elective lumbar surgery.
- Trial name
- NCT01478906
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Xijing Hospital
Hip Fractures, Anesthesia, Local
Shamrock - Ultrasound/MR Image Fusion Guided Lumbar Plexus Block
The main objective is to complete a double-blinded randomized controlled crossover trial of lumbar plexus block with the Shamrock technique guided by ultrasound (US)/magnetic resonance imaging (MRI) image fusion vs.
- Conditions
- Hip Fractures, Anesthesia, Local, Pain, Postoperative
- Trial name
- NCT02718976
- Testing
- Lidocaine-epinephrine added gadoterate meglumine
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Lumbar Spinal Stenosis, Lumbar Disc Herniation
Regional Anesthesia in Minimally Invasive Lumbar Spine Surgery
Opioid overuse is a widespread public health crisis in the United States with increasing rates of addiction and overdose deaths from prescription opioids.
- Conditions
- Lumbar Spinal Stenosis, Lumbar Disc Herniation, Lumbar Spondylolisthesis, Lumbar Spondylosis
- Trial name
- NCT05029726
- Testing
- Bupivacaine-Epinephrine 0.25%-1:200,000 Injectable Solution plus clonidine, normal saline
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- John O'Toole
Postoperative Pain Management
mTLIP vs QIPB for Postoperative Analgesia in Lumbar Microdiscectomy Surgery
The aim of this prospective randomized clinical study is to compare the analgesic efficacy and side effects of modified thoracolumbar interfascial plane block and quadroiliac plane block applied preoperatively in patients…
- Trial name
- NCT07480278
- Testing
- Modified Thoracolumbar Interfascial Plane Block (mTLIP), Quadro-Iliac Plane Block (QIPB)
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Bursa City Hospital
Lumbar Spinal Stenosis
The Vertos MILD™ Preliminary Patient Evaluation Study
This is a single-center, open label, prospective clinical study to assess the clinical application and functional outcomes of symptomatic patients undergoing the Minimally Invasive Lumbar Decompression (MILD™) treatment for…
- Trial name
- NCT00749073
- Testing
- Minimally Invasive Lumbar Decompression (MILD™)
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- Vertos Medical, Inc.
Low Back Pain
Clinical, Morphological and Functional Success Predictors Following Lumbar Spinal Surgery in Patients With Chronic Low Back Pain and Degenerative Disorders.
The long term goal of this project is dual fold. First, the investigators wish to derive, validate and then test the impact of a clinical prediction rule to determine which patients who suffer from CLBP with degenerative changes…
- Trial name
- NCT02444702
- Where
- Israel
- Volunteers
- 200 people
- Sponsor
- Meir Medical Center
Pain
The Effect of Pregabalin and Dexamethasone on Acute and Chronic Pain After Lumbar Spinal Surgery
Multimodal analgesia may be important for optimal postoperative pain treatment and facilitation of early mobilization and recovery.
- Trial name
- NCT01168531
- Testing
- Pregabalin, dexamethasone
- Where
- South Korea
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Intraoperative Bleeding in Lumbar Spine Surgery, Postoperative Pain in Lumbar Spine Surgery
Efficacy of Periarticular Vasoconstrictor Infiltration (PVI) in Reducing Bleeding and Postoperative Pain in Lumbar Fusion Surgery
This retrospective observational study evaluates the efficacy of periarticular vasoconstrictor infiltration (PVI) in reducing intraoperative bleeding and postoperative pain in adult patients undergoing lumbar fusion surgery at…
- Trial name
- NCT07530237
- Testing
- Periarticular Vasoconstrictor Infiltration
- Where
- Spain
- Volunteers
- 25 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Postoperative Cognitive Dysfunction, NEURON SPECIFIC ENOLASE
EFFECT OF ANESTHESİA TECHNIQUES ON POSTOPERATİVE COGNİTİVE DYSFUNCTION FOR MMSE AND NSE LEVEL
The aim of this study is to compare the effects of total intravenous anesthesia and inhalation anesthesia methods on postoperative cognitive dysfunction according to Mini Mental State Examination scores and Neuron Specific…
- Conditions
- Postoperative Cognitive Dysfunction, NEURON SPECIFIC ENOLASE, MINI MENTAL STATE EXAMINATION TEST
- Trial name
- NCT04279132
- Testing
- POSTOPERATIVE COGNITIVE DYSFUNCTION
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Erzincan University
Lumbar Disc Herniation, Lumbar Spinal Stenosis
Long-term Outcomes of Surgical and Nonsurgical Management of Sciatica Secondary to a Lumbar Disc Herniation or Spinal Stenosis
The rate of success 12 months after surgery is reported to be 60-65% in patients with lumbar disc herniation and 60-70% in patients with spinal stenosis.
- Trial name
- NCT02836730
- Testing
- Low back pain surgery
- Where
- Denmark
- Volunteers
- 425 people
- Sponsor
- Back and Rehabilitation Center, Copenhagen
Lumbar Disc Herniation
QLB vs mTLIP for Lumbar Spinal Surgery
Ultrasound-guided quadratus lumborum block (QLB) is a fascial plane block where local anesthetic is injected adjacent to the quadratus lumborum muscle with the goal of anesthetizing the thoracolumbar nerves.
- Trial name
- NCT05217121
- Testing
- Quadratus Lumborum Block, Modified-thoracolumbar interfascial plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Medipol University