Clinical trials: Lumbar Surgery
Spinal Stenosis
Physical Therapy vs Surgical Decompression for Lumbar Spinal Stenosis
This is a randomized controlled multicenter trail comparing physical therapy to surgical decompression in patients with lumbar spinal stenosis.
- Trial name
- PTvsSD (NCT04552145)
- Testing
- surgery, Physiotherapy
- Where
- 3 sites in Norway
- Volunteers
- 232 people
- Sponsor
- Norwegian University of Science and Technology
Lumbar Disc Herniation
Erector Spinae Plane Block and Modified-Thoracolumbar Interfascial Plane Block Following Lumbar Spinal Surgery
Ultrasound (US)-guided peripheral nerve blocks have been used increasily due to the advantages of ultrasound in anesthesia practice. TLIP block is one of these nerve blocks performed under US guidance.
- Trial name
- NCT04073095
- Testing
- Erector spinae plane block (Group E), modified-thoracolumbar interfascial plane block (Group T)
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Medipol University
Low Back Pain, Mechanical, Degenerative Disc Disease Lumbar
Fusion or Not - a Study on Low Back Pain
Problems from the musculoskeletal system are one of the most common reasons for disability and sick leave. These problems include low back pain. Low back pain affects as many as 8 out of 10 individuals at some point in life.
- Trial name
- NCT06709391
- Testing
- Fusion surgery, Non-fusion surgery
- Where
- 4 sites in Sweden
- Volunteers
- 90 people
- Sponsor
- Uppsala University
Cervical Spinal Stenosis, Thoracic Spinal Stenosis
The Effect of Oxytocin Nasal Spray on Preventing Postoperative Delirium in Elderly Patients Undergoing Orthopedic Surgery
Postoperative delirium is a delirium that occurs within 7 days after surgery or before hospital discharge. It has been shown that combined POD can increase the incidence of postoperative pulmonary infections, deep vein thrombosis…
- Conditions
- Cervical Spinal Stenosis, Thoracic Spinal Stenosis, Lumbar Spinal Stenosis, Rotator Cuff Injury
- Trial name
- NCT06945926
- Testing
- oxytocin nasal spray
- Where
- China
- Volunteers
- 227 people
- Sponsor
- Zhejiang University
Lumbar Spinal Stenosis
Long-term Evolution of Patients Suffering From Lumbar Canal Stenosis and Supported by Minimally Invasive Surgery: SUIVISTENO
describe the functional evolution of patients at more than 10 years post intervention. describe the evolution of pain, satisfaction, quality of life of patients to more than 5 years pot intervention.
- Trial name
- SUIVISTENO (NCT04124146)
- Testing
- MRI for some patients according functionnal tests results
- Volunteers
- 100 people
- Sponsor
- Centre Medico-Chirurgicale et Obstetrique Cote d'Opale
Revision Spine Surgery, Fusion of Spine
Pre-Operative Ketamine Infusion for Post Operative Pain Control After Revision Spinal Surgery
To determine if a pre-operative ketamine infusion would provide a similar decrease in post-operative analgesic and opioid consumption as intra-operative ketamine, but expand the monitoring period through the post-operative phase…
- Conditions
- Revision Spine Surgery, Fusion of Spine, Cervical Fusion, Lumbar Fusion
- Trial name
- KIPSs (NCT06066879)
- Testing
- Ketamine Hydrochloride
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- AXIS Spine Center- a division of Northwest Specialty Hospital
Low Back Pain, Kinesiophobia
Investigation of the Effectiveness of Dynamic Neuromuscular Stabilization Exercises After Lumbar Disc Herniation Surgery
The aim of the study is to investigate the effects of dynamic neuromuscular stabilization exercises on pain, functionality and fear in individuals who have undergone lumbar disc herniation surgery.
- Trial name
- NCT06005948
- Testing
- exercise, control
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Uskudar University
Spinal Stenosis of Lumbar Region, Spine Degeneration
Proteomic and Histological Analysis of Ligamentum Flavum in Lumbar Stenosis
Background Lumbar spinal stenosis (LSS) is a common condition characterized by spinal canal narrowing, often linked to ligamentum flavum hypertrophy (LFH) and degeneration.
- Trial name
- APIDeLeG (NCT07026552)
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Postoperative Pain Management
COMPARISON OF THE EFFECTS OF ERECTOR SPINAE PLANE (ESP) BLOCK AND QUADRO İLİAC PLANE (QIP) BLOCK ON POSTOPERATIVE OPIOID CONSUMPTION AND PAIN IN LUMBAR SPINAL SURGERY
COMPARISON OF THE EFFECTS OF ERECTOR SPINAE PLANE (ESP) BLOCK AND QUADRO İLİAC PLANE (QIP) BLOCK ON POSTOPERATIVE OPIOID CONSUMPTION AND PAIN IN LUMBAR SPINAL SURGERY
- Trial name
- NCT07852104
- Testing
- NRS Score, total tramadol consumption, Post Operative Pain Relievers
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Aydin Adnan Menderes University
Mean Blood Pressure
Phentolamine Versus Magnesium Sulphate Infusion During Elective Lumbar Spine Surgery: a Randomized Double Blind Comparative Study
The aim of this study is to evaluate the efficacy of controlled hypotensive anesthesia with phentolamine versus Magnesium sulfate in patients undergoing lumbar spine fusion surgery on blood loss, total dose of hypotensive agents…
- Trial name
- NCT04269980
- Testing
- MAP
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Beni-Suef University
Incisional Hernia, Abdominal Hernia
Hernia Sac Flap Coverage of Mesh in Bony-Edged Ventral Hernia Repair
This trial asks whether covering the inner, bowel-facing surface of a hernia mesh with a flap of the patient's own hernia sac improves healing after repair of a complex ventral (abdominal wall) hernia in which one edge of the…
- Conditions
- Incisional Hernia, Abdominal Hernia, Complex Ventral Hernia, Surgical Site Infection
- Trial name
- PERI-SAC (NCT07720154)
- Testing
- Sac-flap peritonealization of the mesh, Retromuscular (sublay) synthetic mesh repair
- Where
- Egypt
- Volunteers
- 180 people
- Sponsor
- Minia University
Spinal Fusion, Spinal Stenosis
Vancomycin Powder Combined With Autogenous Bone Graft as a Prevention for Post-operative Infection for Spine Surgery
Deep surgical site infection (DSSI) is one of the most challenging complications for spinal surgeons and can lead to a poor clinical outcome.
- Conditions
- Spinal Fusion, Spinal Stenosis, Spondylolisthesis
- Trial name
- NCT03883022
- Testing
- with U-VANCO (vancomycin hydrochloride), without U-VANCO (vancomycin hydrochloride)
- Where
- Taiwan
- Volunteers
- 400 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Degenerative Lumbar Spinal Stenosis, Degenerative Scoliosis
Paraspinal Muscle Degeneration, Bone Mass and Clinical Outcomes in Patients With Lumbar Degenerative Diseases
This study was a retrospective study. The investigators intended to review the preoperative paraspinal muscle imaging data of patients with lumbar spinal stenosis and degenerative scoliosis treated in hospital, and follow up the…
- Trial name
- NCT05190289
- Testing
- Pre-existing degenerative factors of paraspinal muscles and bone mass
- Where
- China
- Volunteers
- 600 people
- Sponsor
- Peking University Third Hospital
Lumbar Disc Herniation, Surgery
The Effect of Ney Music on Patients Undergoing Lumbar Disc Surgery
This randomized controlled study aims to investigate the effects of ney music listening, a traditional Turkish wind instrument, on pain, anxiety, sleep quality, and vital signs in patients undergoing lumbar disc herniation…
- Conditions
- Lumbar Disc Herniation, Surgery, Nurse's Role
- Trial name
- NCT07171008
- Testing
- Ney music
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Niran Çoban
Perioperative Pain
Suprainguinal Fascia Iliaca Block Versus Lumbar Erector Spinae Plane Block for Oncologic Thigh Surgery
This is a prospective; double blinded randomized controlled trial that will be conducted on cancer patients subjected to oncologic thigh surgery.The aim of this study is to evaluate and compare the analgesic effect of…
- Trial name
- NCT05393726
- Testing
- Ultrasound-Guided Suprainguinal Fascia Iliaca Block Versus Lumbar Erector Spinae Plane Block
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- National Cancer Institute, Egypt
Low Back Pain, Opiate Addiction
Study of Opioid Use After Lumbar and Cervical Spine Surgery
The purpose of this project is to assess the impact of an educational video on the use of prescription opioid medication during a 6-month period following spine surgery.
- Conditions
- Low Back Pain, Opiate Addiction, Neck Pain
- Trial name
- SOULCS (NCT02674711)
- Testing
- Educational Video
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Brooke Army Medical Center
Anesthesia Morbidity, Anesthesia; Adverse Effect
Comparison of CLSB With Sedation Versus General Endotracheal Anesthesia on Postoperative Outcomes in Elderly Patients Undergoing Hip Fracture Surgery
Hip fracture is a global public health problem. The postoperative mortality and disability rate of hip fracture is high, and early surgery is still the most effective treatment method, but these patients are often associated with…
- Trial name
- NCT03318133
- Testing
- anesthesia
- Where
- China
- Volunteers
- 1,086 people
- Sponsor
- Shanghai 6th People's Hospital
Lumbar Fusion, Lumbar Spinal Fusion Surgery
Clinical and Biomechanics Research in Core Muscles After Lumbar Fusion Surgery
Lumbar fusion has been widely used for spinal disorders when conservative treatment has failed. However, a number of studies have reported that the rate of re-operation is high for lumbar fusion surgery.
- Trial name
- NCT01703338
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Lumbar Disc Herniation, Lumbar Traction
Comparison of the Effect of Lumbar Traction, Spinal Manipulation, and Surgery in the Treatment of Lumbar Disc Herniation
To compare the effect of lumbar traction, lumbar spinal manipulation and lumbar surgery in the treatment of LDH.
- Conditions
- Lumbar Disc Herniation, Lumbar Traction, Spinal Manipulation, Lumbar Surgery
- Trial name
- NCT03118271
- Testing
- lumbar traction, spinal manipulation, surgery
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Shin Kong Wu Ho-Su Memorial Hospital
Lumbar Disc Herniations
Clinical Effects of Moxibustion Combined With Tailored Baduanjin Exercise Programs on Early Postoperative Rehabilitation in Lumbar Disc Herniation Patients Undergoing Minimally Invasive Surgery
This study is a single-center randomized controlled trial, aiming to explore the effect of moxibustion combined with the modified Baduanjin exercise regimen on the early rehabilitation of patients with lumbar disc herniation…
- Trial name
- NCT07015658
- Testing
- Baduanjin, Moxibustion, Conventional intervention
- Volunteers
- 120 people
- Sponsor
- Suyun Liu