Clinical trials: Lumbar Surgery
Lumbar Spine Degeneration, Arthrosis; Spine
Postoperative Bracing Patterns After Lumbar Surgery
A variety of postoperative bracing are routinely applied after spinal procedures but there are limited data regarding their efficacy, especially with the increasing use of internal fixation.Currently, no data are available…
- Conditions
- Lumbar Spine Degeneration, Arthrosis; Spine, Surgery
- Trial name
- NCT03427281
- Testing
- questionnaire
- Where
- Belgium
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Surgery
The Effect of Bowel Preparation on Perioperative Bleeding
Now a days, due to the change in lifestyle, the extended lifespan and the increase in the rate of the road accidents, the need for surgical operation of spinal instrumentation has been increased.
- Trial name
- NCT02493894
- Testing
- PEG, Cefazolin
- Where
- Iran
- Volunteers
- 105 people
- Sponsor
- Isfahan University of Medical Sciences
Degenerative Lumbar Spinal Stenosis, Degenerative Disc Disease
Effect of Pre-existing Adjacent Segment Degeneration on Long-term Effectiveness After Lumbar Fusion Surgery
This is a prospective single-center study. Patients requiring posterior lumbar interbody fusion (PLIF) for lumbar degenerative disease are prospectively enrolled and followed.
- Conditions
- Degenerative Lumbar Spinal Stenosis, Degenerative Disc Disease, Degeneration Spine
- Trial name
- NCT04467944
- Testing
- Pre-existing degenerative factors at adjacent segment
- Where
- China
- Volunteers
- 210 people
- Sponsor
- Peking University Third Hospital
Postoperative Pain, Lumbar Disc Surgery
Efficacy and Safety of Ultrasound-guided Lateral Thoracolumbar Interfascial Plane Block (TLIPB) for Postoperative Pain in Patients Undergoing Herniated Lumbar Disc Surgery
Surgery of the lumbar spine is characterized by diffuse and severe postoperative pain. In recent years, some case reports indicate that the thoracolumbar interfascial plane block (TLIPB) can reduce postoperative pain after spinal…
- Trial name
- NCT03951038
- Testing
- PCIA group, Lateral TLIPB group
- Where
- China
- Volunteers
- 100 people
- Sponsor
- First Affiliated Hospital of Chongqing Medical University
Low Back Pain
Effect of Lumbar Surgery on Complexity During a Walking Task in Chronic Low Back Pain
Lumbar surgery is the most common treatment for chronic disabling low back pain with degenerative disc disease. There are few elements to objectively evaluate the improvement of the motor control after surgery and the motor…
- Trial name
- LOBAFRACS (NCT05231265)
- Testing
- Walking task
- Where
- 2 sites in France
- Volunteers
- 32 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Lumbar Microdiscectomy Surgery, Lumbar Erector Spinae Plane Block
Comparison of the Analgesic Efficacy of Erector Spinae Plane Block in Lumbar Microdiscectomy Surgeries
Comparison of the Analgesic Efficacy of Lumbar Erector Spinae Plane Block and Sacral Erector Spinae Plane Block in Lumbar Microdiscectomy Surgeries
- Conditions
- Lumbar Microdiscectomy Surgery, Lumbar Erector Spinae Plane Block, Sacral Erector Spinae Plane Block, Postoperative Pain
- Trial name
- NCT07652177
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Lumbar Spine Pathology, Elective Spine Surgery
Neurocognitive and Genomic Predictors of Persistent Pain and Opioid Misuse After Spine Surgery
Having spine surgery and recovery is a vulnerable period when opioid naive patients may transition into long-term use of opioids, and when previously opioid tolerant patients may be at risk to continue towards long-term opioid…
- Trial name
- NCT06288256
- Testing
- No Intervention
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Spinal Stabilization
Comparison of the Effect of Two Methods on Laryngeal Edema in Endotracheal Cuff Inflation
In this study, the investigators aimed to evaluate perioperative laryngeal edema in patients undergoing lumbar stabilization surgery in the pron position, which the investigators use in our routine anesthesia practice, by using…
- Trial name
- NCT06770322
- Testing
- Conventional, manometer
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Cerebrospinal Fluid Leak, Dural Tear
Acetazolamide to Reduce Spinal Fluid Leaks After Spine Surgery.
This study aims to evaluate the effectiveness and safety of acetazolamide in helping patients recover from accidental dural tears during spine surgery.
- Conditions
- Cerebrospinal Fluid Leak, Dural Tear, Incidental Durotomy
- Trial name
- NCT07876713
- Testing
- Acetazolamide, Standard Care (in control arm)
- Where
- Egypt
- Volunteers
- 26 people
- Sponsor
- Ain Shams University
Erector Spinae Plane Block, Lower Extremity Surgery
Regional Anesthesia for Lower Extremity Surgery
In this study, patients who underwent osteosynthesis with plate via standard anterolateral incision due to proximal tibia fracture in the orthopedic clinic within the last year; those who underwent perioperative anesthesia with…
- Conditions
- Erector Spinae Plane Block, Lower Extremity Surgery, Sciatic Nerve Block
- Trial name
- NCT06777953
- Testing
- Erector Spinae (ESP) Block with Lidocaine/Bupivacaine, Popliteal Sciatic Nerve Block
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Haseki Training and Research Hospital
Lumbar Herniated Disk
The Use of a Patient Decision Aid in the Choice of Surgery for Herniated Disc
Even though surgery due to lumbar disc herniation (LDH) shows a more rapid relief of pain and recovery, the evidence of surgery being superior to conservative treatment in the long term is inconclusive.
- Trial name
- NCT03884387
- Testing
- Patient Decision Aid
- Where
- Denmark
- Volunteers
- 142 people
- Sponsor
- Spine Centre of Southern Denmark
Low Back Pain, Lumbar Degenerative Disease
Effects of Health Education for Patients Received Minimally Invasive Lumbar Spinal Surgery
Lumbar degenerative disease surgery has been a routine clinical operation, and has good treatment effects. Although the patient's neurological symptoms improve after surgery, many patients still have postoperative muscle…
- Trial name
- NCT04120532
- Testing
- Perioperative Rehabilitation
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- Taipei Medical University Shuang Ho Hospital
Lumbar Disc Disease
Erector Spinae Plane Block in Spine Surgeries
Aim of this study was to assess the efficacy of erector spinae plane block (ESB) for postoperative pain management in lumbar spine surgery.
- Trial name
- ESB (NCT05247021)
- Testing
- erector spinae block for group E
- Where
- Egypt
- Volunteers
- 44 people
- Sponsor
- Ain Shams University
Adjacent Segment Disease, Lumbar Spinal Stenosis
Surgical Treatment of Adjacent Segment Stenosis
The goal of this clinical trial is to learn whether microdecompression alone is as effective as decompression with extension of fusion surgery in patients with symptomatic adjacent segment stenosis after previous lumbar fusion…
- Trial name
- STASS (NCT07661199)
- Testing
- Microsurgical Decompression with Extension of Fusion, Microsurgical Decompression Alone
- Where
- Germany
- Volunteers
- 338 people
- Sponsor
- Charite University, Berlin, Germany
Blood Loss, Surgical
Effect of Equal Ratio Ventilation on Blood Loss During Posterior Lumbar Interbody Fusion Surgery
Ventilator mode change was associated with decrease in blood loss during posterior lumbar interbody fusion (PLIF) due to decrease in the peak inspiratory pressure (PIP).
- Trial name
- NCT03030963
- Testing
- Equal ratio ventilation(ERV), I:E Ratio "1:2
- Where
- South Korea
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Gangnam Severance Hospital
Back Pain With Radiation, Pain, Postoperative
Spinal Cord Burst Stimulation for Chronic Radicular Pain Following Lumbar Spine Surgery
Spinal cord stimulation (SCS) is a widely applied therapy to treat chronic neuropathic pain, and one of the most common indications is persisting radicular neuropathic pain following lumbar spine surgery.
- Trial name
- NCT03546738
- Testing
- Burst Spinal Cord Stimulation, SCS implant
- Where
- Norway
- Volunteers
- 50 people
- Sponsor
- St. Olavs Hospital
ERAS, Surgery
Enhanced Recovery After Spinal Surgery Protocol Versus Conventional Care in Non Insulin Diabetic Patients ( ERAS )
enhanced recovery after spinal surgery protocol (ERAS) versus conventional care in non insulin diabetic patients. Our hypothesis is that non-insulin dependent diabetic patients who will undergo lumbar decompression surgery…
- Conditions
- ERAS, Surgery, Non Insulin Dependent Diabetes Mellitus, Lumbar Spine Disease
- Trial name
- NCT05033899
- Testing
- ERAS protocol
- Where
- Egypt
- Volunteers
- 72 people
- Sponsor
- Alexandria University
Failed Back Surgery Syndrome
A Post Market Study on DRG Stimulation in FBSS (SYMPATHY)
The purpose of this Post Market Observational Study is to monitor the effect of the Axium® SCS System in the management of chronic pain following surgical lumbar discectomy in subjects whom are routinely scheduled for treatment…
- Trial name
- NCT02634398
- Where
- Switzerland
- Sponsor
- Abbott Medical Devices
Scoliosis, Kyphosis
Comparison of Actifuse ABX and Local Bone in Spinal Surgery
This study is being done to compare people who had a standard of care spinal fusion using part of their local bone graft (a small amount of bone from the region of the spine where the fusion is occurring) to correct an adult…
- Conditions
- Scoliosis, Kyphosis, Lordosis
- Trial name
- NCT01852747
- Testing
- Multilevel Spinal fusion with Actifuse ABX®
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Ohio State University
Spine Disease, Spinal Diseases
Comparison of Perineural Dexamethasone Versus Dexmedetomidine as Adjuvants to Erector Spinae Plane Block in Lumbar Spine Surgery: A Randomized, Double-blind, Controlled Trial
This clinical study aims to determine which of two medications-dexamethasone or dexmedetomidine-works better and is safer when used together with a local anesthetic (ropivacaine) in a type of nerve block called the erector spinae…
- Trial name
- NCT07180940
- Testing
- 0.9%NaCl, Dexamethasone 4mg, Dexmedetomidine
- Where
- Poland
- Volunteers
- 150 people
- Sponsor
- Poznan University of Medical Sciences