Clinical trials: Lumbar Surgery
Lumbar Disc Herniation, Lumbar Disc Surgery
Effectiveness of Virtual Reality-Assisted Physical Therapy in the Acute Phase After Lumbar Disc Surgery
The goal of this clinical trial is to evaluate the effectiveness of virtual reality-assisted physical therapy in the acute postoperative period after lumbar disc surgery.
- Trial name
- NCT07204197
- Testing
- Virtual Reality-Assisted Physical Therapy, Conventional Physical Therapy
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 46 people
- Sponsor
- Hacettepe University
Failed Back Surgery Syndrome, SCS
Spinal Cord Stimulation Versus Instrumentation for FBSS
Low back pain affects people of all ages and has become the leading cause of living with disability worldwide. Patients, suffering from persistent pain after spinal surgery in the absence of any clear spinal pathology are defined…
- Conditions
- Failed Back Surgery Syndrome, SCS, Neuromodulation, Spinal Cord Stimulation
- Trial name
- PROMISE (NCT05466110)
- Testing
- Spinal Cord Stimulation, Spinal Fusion Surgery
- Where
- Germany
- Volunteers
- 84 people
- Sponsor
- University Hospital Augsburg
Spinal Stenosis
MIS-D Versus MIS-TLIF for the Treatment of Lumbar Spinal Stenosis
The purpose of this study is to evaluate the effectiveness of two minimal invasive spine surgery, minimally invasive spinal decompression (MIS-D) and minimally invasive spinal decompression and fusion (MIS-TLIF), for patients…
- Trial name
- NCT04318795
- Testing
- minimally invasive spinal decompression (MIS-D), minimally invasive spinal decompression and fusion (MIS-TLIF)
- Volunteers
- 80 people
- Sponsor
- Third Affiliated Hospital, Sun Yat-Sen University
Lumbar Spinal Stenosis
The NORDSTEN Studies/ The Spinal Stenosis Study
Lumbar Spinal Stenosis (LSS) is a clinical entity were narrowing of the spinal canal gives a compression of the the neural and vascular structures in the spinal canal.
- Trial name
- NORDSTEN/SST (NCT02007083)
- Testing
- Bilateral laminotomy (BL), Unilateral laminotomy with crossover (UL), Spinous Process Osteotomy (SPO)
- Where
- Norway
- Volunteers
- 465 people
- Sponsor
- Haukeland University Hospital
Transforaminal Lumbar Interbody Fusion Surgery
The Objective of the Protocol is to Generate Real World Evidence (RWE) Supporting the Safety, Performance, and Health Economics of Using the Regulatory Approved and Commercially Available EARP Interbody System Used During Lumbar Interbody Fusion (LIF) Procedures With the EARP Nerve Cuff Electrode
The goal of the trial is to generate data to support the safety, performance, and cost effectiveness of using the EARP devices during Lumbar Interbody Fusion (LIF) procedures.
- Trial name
- EARP-2 (NCT07020000)
- Testing
- Device: Nerve Cuff and Retractor System
- Where
- 5 sites in United States
- Volunteers
- 120 people
- Sponsor
- Retropsoas Technologies, LLC
Hip Osteoarthritis
Lumbar Plexus vs Quadratus Lumborum Block in Post-operative Pain Following Total Hip Replacement
The Lumbar Plexus (LP) block is currently used as the standard-of-care regional anesthesia technique to provide postoperative pain management after primary hip replacement surgery at UPMC Shadyside Hospital.
- Trial name
- NCT03801265
- Testing
- Lumbar plexus block, Quadratus lumborum type 3 block, Ropivacaine injection
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Sharad Khetarpal
Spinal Diseases, Endoscopy Simulation
Comparing 3D and 2D Views in Biportal Spine Surgery: A Pilot Simulation Study
This study aims to compare three-dimensional (3D) and two-dimensional (2D) visualization in biportal endoscopic spine surgery using a simulated environment.
- Conditions
- Spinal Diseases, Endoscopy Simulation, Lumbar Vertebrae, Randomized Controlled Trial
- Trial name
- NCT07171801
- Testing
- Three-Dimensional Endoscopic Visualization, Two-Dimensional Endoscopic Visualization
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Felix Corr
Lumbar Spinal Stenosis, Lumbar Disc Herniation
In Turkish Version Lumbar Spine Surgery Expectation Survey
The aim of this study was to determine the Turkish validity and reliability of Lumbar Spine Surgery Expectations Survey developed by Mancuso.
- Conditions
- Lumbar Spinal Stenosis, Lumbar Disc Herniation, Lumbar Radiculopathy, Lumbar Fracture
- Trial name
- NCT04547075
- Testing
- Turkish validity and reliability
- Where
- Turkey (Türkiye)
- Volunteers
- 180 people
- Sponsor
- Kutahya Health Sciences University
Hip Replacement Surgery, Hip Replacement, Total
OPPOSED (anteriOr hiP arthroPlasty regiOnal aneSthEsia stuDy) Study
Main indications for total hip arthroplasty (THA) are degenerative osteoarthritis of the coxofemoral joint, osteonecrosis of the hip, congenital disorders such as dysplasia and inflammatory arthritis.
- Conditions
- Hip Replacement Surgery, Hip Replacement, Total, Hip Pain, Hip Arthroplasty
- Trial name
- NCT07017192
- Testing
- SIFI Block, ESP block
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- A.O.U. Città della Salute e della Scienza
Degenerative Lumbar Spondylolisthesis
Long-term Reoperations After Lumbar Spinal Stenosis Surgery
Severe and persisting pain and disability due to a degenerative narrowing of the spinal canal, lumbar spinal stenosis, can be operated with a simple surgical decompression.
- Trial name
- NCT06407063
- Testing
- Micro-decompression alone, Decompression and instrumented fusion
- Where
- Norway
- Volunteers
- 794 people
- Sponsor
- University Hospital of North Norway
Total Hip Surgery, Pericapsular Nerve
PENG vs. QLB vs. Lumbar ESPB in Total Hip Surgery
The aim of this study is to compare between Pericapsular Nerve Group Block, Erector Spinae Plane Block and Quadratus Lumborum Block for managing acute postoperative pain in patients undergoing total hip surgeries under spinal…
- Conditions
- Total Hip Surgery, Pericapsular Nerve, Quadratus Lumborum, ESPB
- Trial name
- NCT05600244
- Testing
- PENG block Technique, Lumbar ESPB Technique, Transmuscular QLB-t block Technique
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Kafrelsheikh University
Postoperative Pain, Spinal Fusion
Sufentanil NanoTab PCA System/15 mcg for Acute Post-Operative Pain in Vertebral Surgery: A Preliminary Investigation
The Zalviso® Sufentanil Sublingual Tablet System (SSTS) (Grünenthal Italia, Milan, Italy) is a patient-controlled analgesia (PCA) system approved in September 2015 by the European Commission for the management of acute…
- Conditions
- Postoperative Pain, Spinal Fusion, Spondylolisthesis, Lumbar Region, Sufentanil
- Trial name
- NCT03459404
- Testing
- Sufentanil NanoTab PCA System
- Where
- Italy
- Volunteers
- 17 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Quadro-Iliac Plane Block, Erector Spina Plan Block
ESP Block Vs. QIPB for Lumbar Stabilization Surgery
This randomized clinical trial aims to evaluate and compare the analgesic efficacy and functional outcomes of the quadro-iliac plane block (QIPB) and the erector spinae plane block (ESPB) in patients undergoing lumbar…
- Conditions
- Quadro-Iliac Plane Block, Erector Spina Plan Block, Lumbar Stabilization Surgery, Pain Management
- Trial name
- NCT07789509
- Testing
- Quadro iliac Plane Block
- Volunteers
- 60 people
- Sponsor
- Antalya City Hospital
Degenerative Disc Disease
Study of an Expandable Interbody Device for the Lumbar Spine
The primary objective of this study is to evaluate the safety and efficacy of CALIBER expandable spacer for the treatment of degenerative disc disease.
- Trial name
- CALIBER (NCT02075554)
- Testing
- CALIBER
- Where
- 2 sites in United States
- Volunteers
- 58 people
- Sponsor
- Globus Medical Inc
Lumbar Spine Degeneration, Cervical Spine Degeneration
Randomized Controlled Trial Comparing Irrisept Versus Normal Saline for Wound Irrigation After Posterior Spine Surgery
To compare post-operative wound complications in patients randomized to normal saline versus Irrisept solution and any other adverse reactions from the solution.
- Trial name
- Irrisept (NCT05408923)
- Testing
- saline 0.9%, (0.05% chlorhexidine gluconate (CHG) in sterile water)
- Where
- United States
- Sponsor
- University of Missouri-Columbia
PONV
Effect of Combination Dexmedetomidine Added to Fentanyl-based Intravenous Patient-controlled Analgesia on Nausea Vomiting in Highly Susceptible Patients Undergoing Lumbar Spinal Surgery: Prospective Double Blinded Randomized Controlled Trial
The aim of this study is to test the hypothesis that addition of dexmedetomidine to fentanyl-based intravenous patient controlled analgesia (PCA) reduces requirement of fentanyl bolus and consequent postoperative nausea and…
- Trial name
- NCT01840254
- Testing
- dexmedetomidine, normal saline
- Where
- South Korea
- Volunteers
- 108 people
- Sponsor
- Yonsei University
Degenerative Spine Diseases
Minimal Invasive Transforaminal Lumbar Interbody Fusion for Degenerative Lumbar and Lumbosacral Spine Diseases
The aim of this study is to evaluate clinical and surgical outcome of MI-TLIF for degenerative lumbar and lumbosacral spine diseases.
- Trial name
- NCT06545032
- Testing
- lumbar fusion
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Sohag University
Postoperative Pain, Lumbar Spine Surgery
Postoperative Pain Monitoring With ANI in Lumbar Spine Surgery
This study aims to compare two different pain management methods in patients undergoing elective lumbar spine surgery. Patients are randomly assigned to receive either an ultrasound-guided erector spinae plane block (ESPB) or…
- Trial name
- SPINE-ANI (NCT07455565)
- Testing
- Erector Spinae Plane Block, Intravenous Multimodal Analgesia
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Akdeniz University Hospital
Lumbar Spinal Stenosis
Activity Levels Amongst Patients With Lumbar Spinal Stenosis
Lumbar spinal stenosis (LSS) is one of the most common degenerative diseases of the spinal column, with symptoms including low back pain which worsens with ambulation, poor balance, decreased activity due to pain, and a marked…
- Trial name
- B-ATLAS (NCT06057428)
- Testing
- Decompressive surgery
- Where
- 2 sites in Denmark
- Volunteers
- 80 people
- Sponsor
- Region Zealand
Posterior Lumbar Spinal Fusion Surgery
Protective Effect of Tranexamic Acid on Shedding of the Endothelial Glycocalyx in Patients Undergoing Spinal Fusion Surgery
The aim of this study was to determine whether the administration of tranexamic acid in patients undergoing lumbar spinal fusion surgery can inhibit damage in endothelial glycocalyx layer.
- Trial name
- NCT03697681
- Testing
- Tranexamic acid, 0.9% NaCl (normal saline)
- Where
- South Korea
- Volunteers
- 128 people
- Sponsor
- Yonsei University