Clinical trials: Lumbar Surgery
Postoperative Pain
Postoperative Pain Relief After Major Abdominal Gynecological Surgery
The aim of our study was to compare the effects of Lomber Epidural Analgesia (LEA), Transversus Abdominis Plane (TAP) block and Local Anesthetic Infiltration (LAI) on postoperative morphine consumption, time to first recue…
- Trial name
- NCT05845385
- Testing
- lumbar epidural analgesia with bupivacaine, transversus abdominis plane block with bupivacaine, wound infiltration with bupivacaine
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Postoperative Pain Management
mTLIP vs QIPB for Postoperative Analgesia in Lumbar Microdiscectomy Surgery
The aim of this prospective randomized clinical study is to compare the analgesic efficacy and side effects of modified thoracolumbar interfascial plane block and quadroiliac plane block applied preoperatively in patients…
- Trial name
- NCT07480278
- Testing
- Modified Thoracolumbar Interfascial Plane Block (mTLIP), Quadro-Iliac Plane Block (QIPB)
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Bursa City Hospital
Low Back Pain, Sciatica
Non-surgical Spinal Decompression in Patients With Chronic Low Back Pain
The goal of this quasi-experimental trial was to evaluate the effects of non-surgical spinal decompression on disability and pain in patients with chronic low back pain and sciatica throughout a two-month follow-up, and to…
- Conditions
- Low Back Pain, Sciatica, Lumbar Disc Herniation
- Trial name
- NCT06275750
- Testing
- Spinal decompression with BTL-6000 spinal decompression system (BTL Industries Ltd.)
- Where
- Mexico
- Volunteers
- 39 people
- Sponsor
- Hospital Civil de Guadalajara
Postoperative Pain, Lumbar Surgery
Retrolaminar Analgesia for LuMbar Surgery
This randomized controlled trial evaluates the effectiveness of ultrasound-guided retrolaminar nerve block in addition to standard multimodal analgesia for postoperative pain management in patients undergoing lumbar spine…
- Conditions
- Postoperative Pain, Lumbar Surgery, Back Pain Lower Back Chronic, Opioid Analgesia
- Trial name
- REALM (NCT07334288)
- Testing
- Ultrasound-Guided Retrolaminar Block, Standard Analgesia
- Where
- Chile
- Volunteers
- 50 people
- Sponsor
- Universidad de los Andes, Chile
Lumbar Spine Degeneration
Study Using the SpinalStim Device Following Lumbar Fusion Surgery
This study examines the effect of adjunctive use of the SpinalStim bone growth stimulator on lumbar fusion rate in high risk subjects who have had lumbar fusion surgery.
- Trial name
- NCT03176303
- Testing
- SpinalStim
- Where
- United States
- Volunteers
- 206 people
- Sponsor
- Orthofix Inc.
Postoperative Pain Management
Phase 4 Study in Adult Subjects Undergoing Posterior Lumbar Spine Surgeries
Primary Objective: The primary objective of this study is to compare postsurgical opioid consumption through 72 hours postsurgery in patients receiving local infiltration analgesia (LIA) with EXPAREL and bupivacaine HCl (EXPAREL…
- Trial name
- FUSION (NCT03927911)
- Testing
- EXPAREL and Bupivacaine, Standard of Care
- Where
- 12 sites in United States
- Volunteers
- 65 people
- Sponsor
- Pacira Pharmaceuticals, Inc
Spine Surgery, Reversal of Neuromuscular Blockade
Sugammadex vs Neostigmine/Glycopyrrolate on Urinary Retention After Spine Surgery
This is an active-comparator controlled study to evaluate the effect of sugammadex compared to neostigmine/glycopyrrolate for reversal of rocuronium on the incidence of urinary retention after subjects undergo elective ambulatory…
- Conditions
- Spine Surgery, Reversal of Neuromuscular Blockade, Urinary Retention Postoperative
- Trial name
- NCT05887375
- Testing
- Sugammadex, Neostigmine, Glycopyrrolate
- Where
- United States
- Volunteers
- 118 people
- Sponsor
- University of Missouri-Columbia
Adjacent Segment Disease, Lumbar Spinal Stenosis
Surgical Treatment of Adjacent Segment Stenosis
The goal of this clinical trial is to learn whether microdecompression alone is as effective as decompression with extension of fusion surgery in patients with symptomatic adjacent segment stenosis after previous lumbar fusion…
- Trial name
- STASS (NCT07661199)
- Testing
- Microsurgical Decompression with Extension of Fusion, Microsurgical Decompression Alone
- Where
- Germany
- Volunteers
- 338 people
- Sponsor
- Charite University, Berlin, Germany
Normal Pressure Hydrocephalus
Effect of Depletive Lumbar Puncture on Lower Urinary Tract Dysfunction in iNPH
Lower urinary tract dysfunction in normal pressure hydrocephalus has received little attention from the scientific community. Urinary symptoms in normal pressure hydrocephalus are mainly represented by overactive bladder, which…
- Trial name
- PLHPN (NCT03877107)
- Testing
- Urinary symptoms profile questionnaire, Micturition calendar
- Where
- 2 sites in France
- Volunteers
- 100 people
- Sponsor
- EssaiClinique_PL-HPN
Spondyloarthrosis, Spondylosis
Study Confirms or Refutes the Hypothesis That the Autologous Bone Marrow Concentrate Together With the Allograft is a Better Alternative for the Posterolateral Fusion in Spine Surgery Than the Allograft Alone
The use of autologous mesenchymal stem cell (MSCs) in form of the BMC in combination with allograft is an effective option how to enhance the Posterolateral Fusion (PLF) healing.
- Trial name
- NCT01603836
- Testing
- bone allogaft with bone marrow concentrate
- Volunteers
- 80 people
- Sponsor
- Hospital Znojmo
Spondylolisthesis, Lumbar Region, Spinal Trauma With Neurological Deficit
Adult Patient Outcomes After Spine Surgery With Fibergraft BG Putty/Viper Prime
The Viper Prime/Expedium spine systems are intended to provide immobilization and stabilization of spinal segments in skeletally mature patients as an adjunct to fusion in the treatment of acute and chronic instabilities or…
- Conditions
- Spondylolisthesis, Lumbar Region, Spinal Trauma With Neurological Deficit, Degeneration of Lumbar Intervertebral Disc
- Trial name
- NCT06704906
- Testing
- Use of Viper Prime/Expedium system with Fibergraft BG Putty
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Nitin Agarwal
Surgical Injury, Back Pain Lower Back Chronic
Spinal Approach for Lumbar Active Discopathy
The study aims to study the impact on different surgical approaches for lumbar active discopathy. This inflammatory disease of the disc and adjacent vertebral endplates can induce low back pain with inflammatory-like features.
- Trial name
- NCT04086199
- Testing
- Lumbar discectomy
- Where
- Belgium
- Volunteers
- 160 people
- Sponsor
- Centre Hospitalier Régional de la Citadelle
Degenerative Disc Disease, Spondylolisthesis
Pilot Study to Assess Safety/Prelimary Effectiveness of Prefix in Subjects With Degenerative Disc Disease (DDD) Undergoing Spine Fusion Surgery
This is a pilot study to evaulate the safety and prelimary effectiveness of Prefix as compared to autogenous bone for spinal fusion procedures in skeletally mature subjects with degenerative disc disease (DDD) at one level from…
- Trial name
- NCT00798239
- Testing
- Prefix (AMPLEX) B2A Peptide Enhanced Ceramic Granules, Iliac crest autograft
- Where
- 5 sites in Canada
- Volunteers
- 24 people
- Sponsor
- BioSurface Engineering Technologies, Inc
Lumbar Spinal Stenosis
Long-term Follow-up of Conservative and Surgical Treatment Results of Patients With Lumbar Spinal Stenosis
Total of 60 patients with a diagnosis of spinal stenosis is planned for 30 patients, with physical therapy modeling and exercise, and 30 patients with surgical treatment.
- Trial name
- NCT04379765
- Testing
- Exercise and physical therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Anesthesia
Effect of Aminophylline Bolus Versus Infusion on Recovery Time in Patients Undergoing Lumbar Spine Surgery
To determine optimal dose, method and time of administration of aminophylline to enhance the recovery from general anesthesia. andTo estimate the recovery time from isoflurane closure in each group.
- Trial name
- NCT05655806
- Testing
- Aminophylline bolus then infusion, aminophylline bolus, normal saline
- Where
- Egypt
- Volunteers
- 33 people
- Sponsor
- Cairo University
Lactate Blood Increase, Fluid Overload
Goal-directed Fluid Therapy in Elderly Patients Undergoing Lumbar Surgery
This is a randomized controlled clinical trial which investigates whether goal directed fluid therapy( GDT ) would show the evidence of benefit from GDT in terms of lactate kinetics then may reduce postoperative complications in…
- Conditions
- Lactate Blood Increase, Fluid Overload, Postoperative Complications
- Trial name
- NCT03974906
- Testing
- Applying goal-directed fluid therapy by continuous hemodynamic monitoring system (LiDCO）
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Peking Union Medical College Hospital
Spinal Stenosis Lumbar
The Effect of Progressive Muscle Relaxation Exercises on Pain and Disability After Spinal Surgery
This study was planned as a randomized controlled experimental study to determine the effect of progressive muscle relaxation exercises on pain and disability in patients undergoing spinal surgery.
- Trial name
- NCT05253326
- Testing
- Progressive Muscle Relaxation Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Istanbul Medeniyet University
Erector Spina Plan Block, Opioid Consumption
Effects of Erector Spinae Plane Block on Opioid Consumption, Anesthetic Consumption and Hemodynamics in Lumbar Disc Herniation Surgeries.
Lumbar disc herniation (LDH) is an increasingly common spine disorder . In patients treated surgically, inhalation anesthesia and the use of opioids for analgesic purposes are generally the chosen anesthetic methods.
- Conditions
- Erector Spina Plan Block, Opioid Consumption, Postoperative Pain
- Trial name
- NCT06933498
- Testing
- PREOPERATIVE ESPB, INTRAOPERATIVE ESPB
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ankara Ataturk Sanatorium Training and Research Hospital
Lumbar Canal Stenosis
Anterior Discectomy Surgery With Arthrodesis in Degenerative Spinal Canal sténoses. (ICASC)
Single-center retrospective study to characterize changes in the functional capacity of patients (change in Oswestry Desability Index (ODI)) undergoing anterior approach surgery for the management of symptomatic lumbar spinal…
- Trial name
- ICASC (NCT06555887)
- Where
- France
- Volunteers
- 14 people
- Sponsor
- University Hospital, Brest
Degenerative Lumbar Spondylolisthesis
Standardized Perioperative Care Protocol for Lumbar Fusion Surgery
This is a prospective, randomized controlled trial to evaluate whether a comprehensive, standardized perioperative care protocol (SPCP) improves functional recovery, radiographic outcomes, and quality of life compared to…
- Trial name
- NCT07104448
- Testing
- Standardized Perioperative Care Protocol, Conventional care
- Where
- China
- Volunteers
- 382 people
- Sponsor
- Hebei Medical University Third Hospital