Clinical trials: Lumbar Surgery
Spinal Stenosis Lumbar, Disc Degeneration
Efficacy and Safety of Preemptive Intravenous Dexamethasone in MIS-TLIF
Researchers are considering Dexamethasone as preemptive medication before minimally invasive spine fusion surgery to minimize postoperative back pain with minimal side effects, aiming to enhance the effectiveness of surgery and…
- Conditions
- Spinal Stenosis Lumbar, Disc Degeneration, Disc Disease, Fusion of Spine
- Trial name
- MIS-TLIF (NCT06367855)
- Testing
- Dexamethasone, Normal saline
- Where
- Thailand
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Potsawat Surabotsopon
Lumbar Spine Degeneration, Physical Disability
Delphi Study on Rehabilitation Following Lumbar Arthrodesis
Delphi study on perioperative rehabilitation after single and double level lumbar arthrodesis.
- Conditions
- Lumbar Spine Degeneration, Physical Disability, Surgery
- Trial name
- NCT03427294
- Testing
- Delphi study
- Where
- Belgium
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Lumbar Radiculopathy
The Effectiveness of Pain Neuroscience Education in At-risk Patients Following Surgery for Lumbar Radiculopathy
This study aims to assess the effectiveness of perioperative pain neuroscience education (PPNE) in patients who are at risk for unfavorable outcome following surgery for lumbar radiculopathy.
- Trial name
- B²EARS (NCT05047679)
- Testing
- Perioperative Pain Neuroscience Education, Perioperative Biomedical Education
- Where
- 4 sites in Belgium
- Volunteers
- 6 people
- Sponsor
- Vrije Universiteit Brussel
Lumbar Spinal Stenosis, Lumbar Disc Herniation
Dexamethasone as Adjuvant to Ropivacaine in Wound Infiltration for Postoperative Analgesia Following Spinal Surgery
Introduction: Improving postoperative pain management after spinal surgery is a significant challenge for surgeons and anesthesiologists.
- Conditions
- Lumbar Spinal Stenosis, Lumbar Disc Herniation, Lumbar Spondylolisthesis, Lumbar Spine Instability
- Trial name
- NCT05871073
- Testing
- Ropivacaine 0.75% Injectable Solution, dexamethasone 8mg
- Where
- Tunisia
- Volunteers
- 60 people
- Sponsor
- University Hospital Fattouma Bourguiba
Hip Surgery
Comparison Between 2 Techniques for Lumbar-ESPB
Diffusion of local anesthetics after a lumbar ESPB within fascial planes towards nerve structures is a matter of debate. The main objective of the study is to compare the incidence of sensory block between two techniques of…
- Trial name
- ESPTA (NCT07104097)
- Testing
- spinal anesthesia, superficial erector spinal plane block (ESPB), deep (inter laminar) erector spinal plane block (ESPB)
- Where
- Italy
- Volunteers
- 44 people
- Sponsor
- Papa Giovanni XXIII Hospital
Chronic Low-back Pain
The Lumbar Interbody Fusion vs. Multidisciplinary Rehabilitation (LIFEHAB) Trial
The goal of this randomized controlled trial is to compare lumbar interbody fusion surgery with multidisciplinary rehabilitation in participants aged 20-65 years with persisting (≥ one year) low back pain.
- Trial name
- LIFEHAB (NCT06169488)
- Testing
- Lumbar Interbody Fusion, Multidisciplinary rehabilitation
- Where
- 5 sites in Norway
- Volunteers
- 202 people
- Sponsor
- Oslo University Hospital
Lumbar Disc Herniation, Lumbar Disc Disease
GA + ESP vs. SA + ESP in Lumbar Decompression Surgeries
The purpose of this study is to determine the optimal anesthetic routine for lumbar decompression surgery. General Anesthesia is the standard of care in spine surgery.
- Conditions
- Lumbar Disc Herniation, Lumbar Disc Disease, Lumbar Radiculopathy
- Trial name
- NCT05444751
- Testing
- General anesthetic, SA + ESP
- Where
- United States
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- Hospital for Special Surgery, New York
Acute Postoperative Pain
Ultrasound Guided Bilateral Erector Spinae Block Versus Caudal in Lumbar Spine Surgeries
Major lumbar spine surgeries are associated with severe postoperative pain that usually lasts for at least 3 days.Caudal epidural analgesia has a crucial role in providing effective pain relief post lumbar spine surgeries by…
- Trial name
- NCT05351203
- Testing
- caudal block, Erector spinae block
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
Revision Spine Surgery, Fusion of Spine
Pre-Operative Ketamine Infusion for Post Operative Pain Control After Revision Spinal Surgery
To determine if a pre-operative ketamine infusion would provide a similar decrease in post-operative analgesic and opioid consumption as intra-operative ketamine, but expand the monitoring period through the post-operative phase…
- Conditions
- Revision Spine Surgery, Fusion of Spine, Cervical Fusion, Lumbar Fusion
- Trial name
- KIPSs (NCT06066879)
- Testing
- Ketamine Hydrochloride
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- AXIS Spine Center- a division of Northwest Specialty Hospital
Lumbar Stenosis, Familial
Place of Ultrasound Guidance of Surgery Site in Surgery for Lumbar Canal Stenosis and Lumbar Disc Herniations
The identification of the operative site of lumbar ductal stenosis and lumbar disc herniation is classically done by radioscopy, thus inducing irradiation of the patient.
- Trial name
- NCT04124627
- Testing
- Ultrasound guidance in addition to radiographic guidance
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Centre Medico-Chirurgicale et Obstetrique Cote d'Opale
Lumbar Disc Herniation
Preoperative Magnetic Resonance Imaging Abnormalities Predictive of Lumbar Herniation Recurrence
There are currently no standard criteria for evaluating the risk of recurrent disk herniation following surgical repair. This study investigated the predictive values of five presurgical imaging parameters, paraspinal muscle…
- Trial name
- NCT05246241
- Testing
- magnetic resonance imaging
- Where
- Turkey (Türkiye)
- Volunteers
- 188 people
- Sponsor
- Ataturk University
Chronic Low Back Pain, After Lumbar Spine Surgery
Efficacy of Cognitive Functional Therapy in Individuals With Chronic Low Back Pain After Spinal Surgery
Chronic low back pain after spinal surgery is a complex and disabling condition influenced by biopsychosocial factors. Cognitive Functional Therapy (CFT) is a promising intervention targeting these multidimensional aspects.
- Conditions
- Chronic Low Back Pain, After Lumbar Spine Surgery, Failed Back Surgery Syndrome (FBSS)
- Trial name
- NCT07576062
- Testing
- CFT
- Volunteers
- 90 people
- Sponsor
- Centro Universitário Augusto Motta
Low Back Pain
Clinical, Morphological and Functional Success Predictors Following Lumbar Spinal Surgery in Patients With Chronic Low Back Pain and Degenerative Disorders.
The long term goal of this project is dual fold. First, the investigators wish to derive, validate and then test the impact of a clinical prediction rule to determine which patients who suffer from CLBP with degenerative changes…
- Trial name
- NCT02444702
- Where
- Israel
- Volunteers
- 200 people
- Sponsor
- Meir Medical Center
Intraoperative Bleeding in Lumbar Spine Surgery, Postoperative Pain in Lumbar Spine Surgery
Efficacy of Periarticular Vasoconstrictor Infiltration (PVI) in Reducing Bleeding and Postoperative Pain in Lumbar Fusion Surgery
This retrospective observational study evaluates the efficacy of periarticular vasoconstrictor infiltration (PVI) in reducing intraoperative bleeding and postoperative pain in adult patients undergoing lumbar fusion surgery at…
- Trial name
- NCT07530237
- Testing
- Periarticular Vasoconstrictor Infiltration
- Where
- Spain
- Volunteers
- 25 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Post-Operative Pain
Pregabalin Versus Celecoxib on Sevoflurane and Analgesic Consumption in Spine Fixation Surgery
The anti-epileptic drugs such as gabapentin and other non-steroidal anti-inflammatory drugs (NSAID) such as celecoxib were used as a part of multimodal analgesia to control such pain.
- Trial name
- NCT04342065
- Testing
- Celecoxib capsules, Pregabalin 150mg
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- South Egypt Cancer Institute
Lumbar Herniated Disc
Ozone Therapy in Patients on Waiting List for Surgery Due to Disc Herniation: Prospective, Post-authorization Study
The main objective of this study is to estimate the cost-effectiveness of ozone therapy in patients on the waiting list for surgery due to disc herniation.
- Trial name
- O3HDCIRUGIA (NCT03282695)
- Where
- Spain
- Volunteers
- 70 people
- Sponsor
- Bernardino Clavo, MD, PhD
Degenerative Spine Disease, Spinal Stenosis Lumbar
VR-Cognitive Behavioral Therapy Prehabilitation for Spinal Deformity Surgery
The goal of this clinical trial is to learn whether a virtual reality-based cognitive behavioral therapy (VR-CBT) prehabilitation program can improve recovery and quality of life for adults undergoing elective spine surgery.
- Trial name
- VR-CBT (NCT07777679)
- Testing
- Virtual Reality-Based CBT Prehabilitation (VR-CBT), CBT Prehabilitation without Virtual Reality
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- University of California, Irvine
Surgical Site Infections, Lumbar Disc Herniation
The Effect of Number of Showers With 4% Chlorhexidine Gluconate on Prevention of Surgical Site Infections
Surgical site infections (SSIs) are the most common type of nosocomial infection in surgical departments. Although lumbar disc herniation (LDH), which is one of the common cases in neurosurgery, is a serious problem affecting…
- Trial name
- SSI (NCT06801275)
- Testing
- 1 shower with 4% chlorhexidine gluconate, 2 shower with 4% chlorhexidine gluconate
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Çanakkale Onsekiz Mart University
Sacroiliac Joint Disruption, Scoliosis Lumbar Region
SI Joint Stabilization in Long Fusion to the Pelvis
The purpose of this study is to compare outcomes of subjects undergoing multilevel lumbar fusion (MLF) surgery with and without the iFuse 3-D implants in the "bedrock" trajectory.
- Trial name
- SILVIA (NCT04062630)
- Testing
- iFuse 3-D in Bedrock Configuration, Multilevel Lumbar Fusion surgery
- Where
- 31 sites in United States, Australia and 3 more
- Volunteers
- 213 people
- Sponsor
- SI-BONE, Inc.
Lumbar Spinal Stenosis
Activity Levels Amongst Patients With Lumbar Spinal Stenosis
Lumbar spinal stenosis (LSS) is one of the most common degenerative diseases of the spinal column, with symptoms including low back pain which worsens with ambulation, poor balance, decreased activity due to pain, and a marked…
- Trial name
- B-ATLAS (NCT06057428)
- Testing
- Decompressive surgery
- Where
- 2 sites in Denmark
- Volunteers
- 80 people
- Sponsor
- Region Zealand