Clinical trials: Lumbar Surgery
Isthmic Spondylolisthesis, Surgical Procedure, Unspecified
Isthmic Spondylolisthesis Treated With Combined Approach: Clinical and Radiological Outcomes
This study aims to evaluate clinical and radiological outcomes of isthmic spondylolisthesis surgically treated with combined approach.
- Trial name
- SPLAC (NCT03585439)
- Testing
- Observational study evaluating the results of an intervention for isthmic spondylolisthesis: surgical procedure with double approach: Anterior lumbar Interbody Fusion then postero-lateral fusion
- Where
- France
- Volunteers
- 87 people
- Sponsor
- CMC Ambroise Paré
Lumbar Spinal Stenisis or Lumbar Herniated Intervertebral Disc
The Analgesic Effect of Nefopam on the Fentanyl Based PCA (Patient-controlled Analgesia) After Lumbar Spinal Surgery
Posterior lumbar spinal surgical pain leads to a severe degree of pain, and, hence, various means of pain management are required.
- Trial name
- NCT01808014
- Testing
- nefopam
- Where
- South Korea
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Postoperative Pain, PCA Contramal Consumption
Efficacy of Intravenous Naproksen Sodium+Codein and Paracetamol+Codein on Postoperative Pain on Postoperative Pain
Comparition the analgesic effects of intravenous naproksen sodyum+codein with that of paracetamol+codein on postoperative pain and contramal consumption during the first 24 hour after a lumbar disk surgery.
- Trial name
- NCT02252614
- Testing
- naproxen sodium codein, paracetamol codein
- Volunteers
- 75 people
- Sponsor
- Diskapi Yildirim Beyazit Education and Research Hospital
Blood Loss
Hemostatic Agent Use and Intraoperative Blood Loss in Lumbar Spine Surgery
Perioperative variables that can be used to create a bundled approach quality improvement protocol to minimize blood loss in spine surgery will be evaluated using retrospective data collection and multivariate analysis of…
- Trial name
- NCT04058665
- Testing
- Floseal
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Johns Hopkins University
Lumbar Spinal Stenosis
The iO-Flex® Study: Evaluation of the Baxano iO-Flex® System for Decompressive Lumbar Surgery
The purpose of this study is to evaluate the clinical performance of the iO-Flex® System in reducing pain and symptom severity in patients with one or two level lumbar spinal stenosis that requires surgery.
- Trial name
- NCT01067014
- Testing
- Baxano iO-Flex® System
- Where
- 18 sites in United States
- Volunteers
- 75 people
- Sponsor
- Baxano Surgical, Inc.
Spinal Stenosis
The Impact of Epidural Fat Resection on Postoperative Outcomes in Posterior Surgery of Lumbar Spine
Posterior lumbar epidural fat commonly had been considered a simple space-filling tissue. Anatomic studies on posterior epidural space and its contents are few, including semifluid property.
- Trial name
- NCT02127008
- Testing
- Resection of epidural fat, No resection of epidural fat
- Where
- South Korea
- Volunteers
- 185 people
- Sponsor
- Seoul National University Hospital
Lumbar Spinal Degeneration
Analysis of Three-Dimensional Navigated Lateral Lumbar Interbody Fusion
This observational study evaluates the clinical outcomes and procedural characteristics of navigation-assisted oblique lumbar interbody fusion (OLIF) in patients with lumbar degenerative disease.
- Trial name
- NCT07437118
- Where
- Taiwan
- Volunteers
- 11 people
- Sponsor
- MengTingWu
Post Operative Sore Throat
A Postoperative Sore Throat After Lumbar Spine Surgery in the Prone Position
This study was performed to compare the effect of dexmedetomidine and remifentanil on the incidence and severity of postoperative sore throat in patients undergoing spinal surgery in the prone position who are at risk of…
- Trial name
- NCT05345574
- Testing
- dexmedetomidine infusion, remifentanil infusion
- Where
- South Korea
- Volunteers
- 104 people
- Sponsor
- Yeungnam University College of Medicine
Lumbar Disc Herniation
Telerehabilitation After Lumbar Disc Herniation Surgery
This randomized controlled trial evaluated the effectiveness of a telerehabilitation-based exercise program in individuals who had undergone surgery for lumbar disc herniation.
- Trial name
- NCT07889817
- Testing
- Home Exercise Program, Telerehabilitation-Based Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people
- Sponsor
- Hasan Kalyoncu University
Lumbar Disc Herniation, Lumbar Spinal Stenosis
Application of 3D Printing Guide Plate in Spinal Minimally Invasive and Interventional Surgeries
Application of 3D printing guide plate in spinal minimally invasive and interventional surgeries
- Conditions
- Lumbar Disc Herniation, Lumbar Spinal Stenosis, Radiculopathy, Lumbosacral Facet Joint Syndrome
- Trial name
- NCT05487690
- Testing
- 3D printing guide plate, Conventional guidance
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Peking University Third Hospital
Lumbar Disc Herniation
Post-marketing Clinical Follow-up of the Medical Device DIVA®
Observational, ambispective, longitudinal, comparative, open, multicentric study. The main objective is to compare the performance of care in patients operated with and without DIVA®.
- Trial name
- NCT05277818
- Testing
- Surgery lumbar disc herniation
- Where
- France
- Volunteers
- 822 people
- Sponsor
- SC Medica
Degenerative Spondylolisthesis, Spinal Stenosis
First-In-Human Study of AK1320 Encapsulated Microspheres (AK1320 MS)
The safety and efficacy of AK1320 MS will be evaluated in patients with degenerative spondylolisthesis and concomitant symptomatic spinal stenosis who are undergoing decompression and single level instrumented posterolateral…
- Trial name
- ENHANCE (NCT04483297)
- Testing
- AK1320 MS, Control
- Where
- 7 sites in Canada
- Volunteers
- 30 people
- Sponsor
- Asahi Kasei Therapeutics Corporation
Low Back Pain, Kinesiophobia
Investigation of the Effectiveness of Dynamic Neuromuscular Stabilization Exercises After Lumbar Disc Herniation Surgery
The aim of the study is to investigate the effects of dynamic neuromuscular stabilization exercises on pain, functionality and fear in individuals who have undergone lumbar disc herniation surgery.
- Trial name
- NCT06005948
- Testing
- exercise, control
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Uskudar University
Trigger Point Pain, Myofascial
Trigger Point Incidence After Lumbar Disc Herniation Surgery
Our purpose is to determine the incidence of trigger points in patients who remain in a fixed position for a long time during lumbar disc herniation surgery.
- Trial name
- NCT04136197
- Testing
- Manual palpation for incidence determination
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- Istanbul University - Cerrahpasa
Radiculopathy, Herniated Disk
Percutaneous Diskectomy SpineJet x Open Microdiskectomy in Treatment of Lumbar Radiculopathy
Approximately 300,000 patients undergo open surgical procedures to treat symptoms caused by disc herniation. Among the various surgical techniques practiced the percutaneous discectomy occupies its space since the first…
- Trial name
- PDOP_TLR (NCT01367860)
- Testing
- Open microdiscectomy, Percutaneous Diskectomy SpineJet
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Postoperative Pain, Spinal Fusion
Sufentanil NanoTab PCA System/15 mcg for Acute Post-Operative Pain in Vertebral Surgery: A Preliminary Investigation
The Zalviso® Sufentanil Sublingual Tablet System (SSTS) (Grünenthal Italia, Milan, Italy) is a patient-controlled analgesia (PCA) system approved in September 2015 by the European Commission for the management of acute…
- Conditions
- Postoperative Pain, Spinal Fusion, Spondylolisthesis, Lumbar Region, Sufentanil
- Trial name
- NCT03459404
- Testing
- Sufentanil NanoTab PCA System
- Where
- Italy
- Volunteers
- 17 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Lumbar Disc Herniation, Emergence Agitation
Magnesium Sulfate for Prevention of Emergence Agitation in Lumbar Disc Surgery
In this retrospective study, the effect of intraoperative magnesium sulfate infusion on the incidence of postoperative emergence agitation was evaluated in adult patients who underwent elective lumbar microdiscectomy under…
- Conditions
- Lumbar Disc Herniation, Emergence Agitation, Magnesium Sulfate
- Trial name
- NCT07139847
- Testing
- Magnesium Sulfate Infusion, 0.9% Saline Infusion
- Volunteers
- 70 people
- Sponsor
- Ondokuz Mayıs University
Postoperative Pain
Comparison of Postoperative Analgesic Efficacy of Intravenous Dexketoprofen Trometamol With Tenoxicam
In this study the investigators aimed to compare of postoperative analgesic effects of intravenous dexketoprofen trometamol and tenoxicam in lumbar disc surgery.
- Trial name
- NCT02160236
- Testing
- dexketoprofen trometamol, tenoxicam, serum physiologic
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- TC Erciyes University
Lumbar Spondylosis, Lumbar Spinal Stenosis
Modified Enhanced Recovery After Oblique Lateral Interbody Fusion Surgery
The goal of this randomized clinical trial is to investigate whether modified enhanced recovery after surgery (ERAS) in oblique lumbar interbody fusion (OLIF) can shorten the postoperative hospital stay among patients with lumbar…
- Conditions
- Lumbar Spondylosis, Lumbar Spinal Stenosis, Lumbar Disc Herniation
- Trial name
- MERAOLIS (NCT05854043)
- Testing
- Modified ERAS protocol, routine protocol
- Where
- China
- Volunteers
- 96 people
- Sponsor
- Xuanwu Hospital, Beijing
Foley Catheterization, Ambulation
Early Versus Delayed Urinary Catheter Removal After Minimally Invasive Lumbar Spine Surgery
The study aims to compare between early versus delayed urinary catheter removal the impact on time to ambulation (in minutes) after minimally invasive lumbar spine surgery
- Trial name
- EDUCaRe (NCT05359926)
- Testing
- Experimental, Active comparator
- Where
- United States
- Sponsor
- University of Kansas Medical Center