Clinical trials: Lumbar Surgery
Lumbar Spinal Stenosis, Lumbar Disc Herniation
Research on Key Technology Development and Clinical Application of Small Interactive Spinal Endoscopic Surgery Robot
The aim of the study was to investigate the correlation between the extent of decompression and patient follow-up metrics at 1 year postoperatively by analysing data from a real-world, multicentre cohort of patients, and to…
- Trial name
- NCT06480214
- Testing
- endoscopic spine surgery
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Beijing Jishuitan Hospital
Postoperative Pain
Lumbar Erector Spinae Plane Block and Quadratus Lumborum Block in Hip and Proximal Femur Surgeries
Multimodal analgesia is used to control postoperative pain in hip surgery. Quadratus lumborum block is an effective regional anesthesia technique for hip and proximal femur surgery.
- Trial name
- NCT03508544
- Testing
- Lumbar ESP block, QLB bLock, Standard Pain Followup and Monitorization
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Maltepe University
Bone Marrow, Spinal Fusion
Autologous Bone Marrow Concentrate in Elective Tranforaminal Lumbar Interbody Fusion Surgery
This study aims to evaluate the effect of bone marrow concentration on bone healing and spinal fusion by comparing clinical and imaging outcomes between patients receiving transforaminal lumbar intebody fusion with local bone…
- Trial name
- NCT03793530
- Testing
- Transforaminal lumbar interbody fusion with local bone graft and intraoperative bone marrow concentration, Transforaminal lumbar interbody fusion with local bone graft
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- Pei-Yuan Lee, MD
Hip Fractures, Anesthesia, Local
Shamrock - Ultrasound/MR Image Fusion Guided Lumbar Plexus Block
The main objective is to complete a double-blinded randomized controlled crossover trial of lumbar plexus block with the Shamrock technique guided by ultrasound (US)/magnetic resonance imaging (MRI) image fusion vs.
- Conditions
- Hip Fractures, Anesthesia, Local, Pain, Postoperative
- Trial name
- NCT02718976
- Testing
- Lidocaine-epinephrine added gadoterate meglumine
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Pain, Postoperative
mTLIP vs QIPB for Postoperative Analgesia After Lumbar Instrumentation Surgery
Lumbar instrumentation surgery is associated with severe postoperative pain due to extensive tissue dissection and prolonged muscle retraction during the procedure.
- Trial name
- NCT07370415
- Testing
- Modified Thoracolumbar Interfascial Plane Block (mTLIP), Quadro-Iliac Plane Block (QIPB):
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Bursa City Hospital
Pain, Neuropathic
Can Dexmedetomidine With Hyalase Augment Quality and Duration of Analgesia When Added to Lumbar Epidural Steroid in Failed Back Surgery. Randomized Double Blind Study
use of dexmedtemodine to augment analgesia in cases of failed back surgery
- Trial name
- NCT05349448
- Testing
- Hylase plus Triamcinolone plus sterile isotonic saline, Hylase plus Dexmedetomidine plus Triamcinolone
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Minia University
Lumbar Disc Herniation, Surgery
The Effect of Ney Music on Patients Undergoing Lumbar Disc Surgery
This randomized controlled study aims to investigate the effects of ney music listening, a traditional Turkish wind instrument, on pain, anxiety, sleep quality, and vital signs in patients undergoing lumbar disc herniation…
- Conditions
- Lumbar Disc Herniation, Surgery, Nurse's Role
- Trial name
- NCT07171008
- Testing
- Ney music
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Niran Çoban
Lumbar Fusion Surgery
IO Vancomycin Spine
The goal of this research is to learn if injecting the antibiotic vancomycin directly into the bone marrow (intraosseous) or IO) during a lumbar (spinal) fusion surgery, is as effective or better than the standard method of…
- Trial name
- NCT06748144
- Testing
- Intraosseous Vancomycin, Intravenous Vancomycin
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- The Methodist Hospital Research Institute
Prolapse
Rehabilitation After Lumbar Disc Surgery: Exercise Therapy and Brief Educational Intervention
Rehabilitation after lumbar disc surgery (prolapse) focuses on various elements such as endurance, strength, stretching and information.
- Trial name
- NCT01779544
- Testing
- Brief intervention, an educational model, Exercise therapy
- Where
- Norway
- Volunteers
- 70 people
- Sponsor
- Haukeland University Hospital
Failed Back Surgery Syndrome
A Post Market Study on Dorsal Root Ganglion (DRG) Stimulation in Failed Back Surgery Syndrome (FBSS)
18-SMI-2013 is a post market, observational, questionnaire based study to assess the effectiveness of the commercially available Axium neurostimulator in the management of chronic pain following lumbar discectomy (Failed Back…
- Trial name
- SYMPATHY (NCT02335216)
- Testing
- Implantation with the commercially available Axium neurostimulator
- Where
- Netherlands
- Volunteers
- 22 people
- Sponsor
- Abbott Medical Devices
Discogenic Low Back Pain, Intervertebral Disc Degeneration
RenewDisc Trial: Endoscopic Discectomy and Autologous Stem Cell Therapy for Discogenic Low Back Pain
he RenewDisc Trial is a prospective observational clinical study evaluating outcomes in patients with confirmed discogenic low back pain who undergo standard clinical care using endoscopic spine procedures.
- Conditions
- Discogenic Low Back Pain, Intervertebral Disc Degeneration, Lumbar Disc Disease, Chronic Low Back Pain
- Trial name
- RENEWDISC (NCT07338877)
- Where
- Slovakia
- Volunteers
- 120 people
- Sponsor
- EPC Education s.r.o.
Lumbar Decompression
MRI Outcomes of VersaWrap Nerve Protector Following Surgery
The purpose of this study is to evaluate enhancement patterns in magnetic resonance imaging (MRI) evidence following the use of VersaWrap in bilateral lumbar decompression surgeries.
- Trial name
- NCT06942819
- Testing
- VersaWrap Nerve Protector
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Research Source
Chronic Low Back Pain, Lumbar Degenerative Disc Disease
Safety and Performance Study of the CAdiscTM-L Lumbar Spinal Disc Replacement Device For CE Marking
The purpose of this European Union (EU) study to evaluate the safety and performance of the CAdiscTM-L Lumbar Spinal Disc Replacement Device in the surgical replacement of the lumbar intervertebral discs (L3 to S1) for patients…
- Trial name
- DISCERN (NCT00949936)
- Testing
- CAdisc™-L (Total Disc Replacement)
- Where
- 4 sites in Belgium, Germany and 2 more
- Sponsor
- Ranier Technology Limited
Foraminal Stenosis
Comparative Outcomes of Conventional TLIF With Posterior Decompression Surgery Versus Endoscopic Foraminotomy Surgery
Comparative Outcomes of Conventional Transforaminal Lumbar Interbody Fusion With Posterior Decompression Surgery Versus Endoscopic Foraminotomy Surgery in Stable Lumbar Foraminal Stenosis An Ambi-directional Cohort Study
- Trial name
- TLIF (NCT06685575)
- Testing
- Endoscopic Foraminotomy Surgery
- Where
- Thailand
- Volunteers
- 52 people
- Sponsor
- Queen Savang Vadhana Memorial Hospital, Thailand
Lumbar Disc Disease, Surgical Procedure, Unspecified
Evaluation of the Contribution of Intraoperative Scans Coupled With the Navigation for the Precision of the Positioning of the Pedicle Screws During a Lumbar Spine Surgery: a Prospective Randomised Study
Investigators team propose to evaluate the impact of the use of intraoperative scanning coupled with Stryker navigation, compared to the conventional fluoroscopy technique, on the accuracy of pedicle screws, in instrumented…
- Trial name
- SCANRACH (NCT04134975)
- Testing
- Spine surgery
- Where
- France
- Volunteers
- 126 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Spondylolisthesis, Lumbar Disc Herniation
Erector Spinae Plane Block as Pain Management After Lumbar Fusion Surgery
Rationale: Lumbar spine surgery is associated with high postoperative pain scores and analgesic use, despite use of multimodal analgesia.
- Conditions
- Spondylolisthesis, Lumbar Disc Herniation, Lumbar Spinal Stenosis, Lumbar Disc Disease
- Trial name
- RCT-ESPB (NCT05345249)
- Testing
- Ropivacaine Hydrochloride Injection, Sodium chloride
- Where
- Netherlands
- Volunteers
- 76 people
- Sponsor
- Ilse van de Wijgert
Postoperative Pain
Erector Spinae Plane Block For Lumbar Disc Hernia Repair
Pain management after lomber disc hernia repair surgery is a challenging issue for anesthetists. Erector Spinae plane block is a novel analgesic technique which could be used for this purpose.
- Trial name
- NCT03744689
- Testing
- Erector Spinae Plane block, Bupivacaine Hydrochloride, PCA
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Kocaeli University
Hip Arthroplasty
Peripheral Nerve Block vs Spinal Anesthesia in Hip Surgery
Anesthesia plays an important role in the patient's outcome: each anesthesiological technique has a different cardiovascular impact, because they act differently on the autonomic nervous system, which in turn regulates heart…
- Trial name
- NCT04506450
- Testing
- Peripheral nerve block, Spinal anesthesia
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Università Politecnica delle Marche
Lumbar Spine Disc Herniation
Effects of Addition of Magnesium Sulfate in Spinal Anesthesia on Sensory-Motor Blocks and Postoperative Pain in Lumbar Disk Herniation Surgery
The purpose of this study is to Compare three methods of intrathecal bupivacaine; bupivacaine-fentanyl; bupivacaine-fentanyl-magnesium sulfate on sensory-motor blocks and postoperative pain in patients undergoing lumbar disk…
- Trial name
- NCT01843296
- Testing
- Magnesium Sulfate, Spinal Anesthesia, Bupivacaine
- Where
- Iran
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Isfahan University of Medical Sciences
Opioid Consumption, Quality of Recovery(QoR-40), Preoperative and Postoperative
The Effects of ESP Block and Mid-Transverse Process to Pleura Block on Postoperative Opioid Consumption and Quality of Recovery
Erector Spinae Area (ESP) Block and Mid-Transverse Process to Pleura Block(MTP) have recently been described for the treatment of pain after lumbar spinal surgery.
- Trial name
- NCT06815146
- Testing
- Numeretic rating scale (NRS), Quality of Results (QoR-40), Opioid consuption
- Volunteers
- 126 people
- Sponsor
- Aydin Adnan Menderes University