Clinical trials: Lumbar Surgery
Spine Surgery
"Efficacy of Hybrid Systems ("Topping Off") Versus Rigid Spinal Fusion in Lumbar Fusion Surgery: A Dual-center, Prospective, Randomized Pilot Study ("CD Horizon BalanC")"
Effectiveness of hybrid systems ("topping off") compared to rigid spondylodesis in fusion surgery of the lumbar spine: A prospective, randomized, bicentric pilot study ("CD HORIZON BalanC™)
- Trial name
- BalanC (NCT02551302)
- Testing
- Solera™ Medtronic, CD HORIZON BalanC™ Medtronic
- Volunteers
- 60 people
- Sponsor
- University of Cologne
Haemodynamic Changes During During Emergence, Airway Response During Emergence
Prone Position Emergence From Anaesthesia in Lumbar Disc Surgery
Compare haemodynamic changes and to evaluate the incidence of coughing, laryngospasm, loss of monitoring in patients undergoing lumbar disc surgery extubated in prone position and supine position.
- Conditions
- Haemodynamic Changes During During Emergence, Airway Response During Emergence, Monitor Disconnection During Emergence
- Trial name
- NCT01441700
- Testing
- Prone and Supine emergence from anaesthesia
- Volunteers
- 50 people
- Sponsor
- KVG Medical College and Hospital
Lumbar Radiculopathy, Radicular Low Back Pain
R³ Rehab Pathway Versus Usual Care After Lumbar Radicular Surgery
The R³ trial is a multicentre cluster randomized controlled trial evaluating an evidence-based, person-centred rehabilitation pathway for patients undergoing lumbar surgery for radicular pain.
- Trial name
- R³ (NCT07313566)
- Testing
- R³ Rehabilitation Pathway
- Where
- 16 sites in Belgium
- Volunteers
- 480 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Lumbar; Injury
A Single Session Pain Psychology Class for Spine Surgery Patients
This project tests the feasibility a single session pain psychology class (TREK for Surgical Success) for patients undergoing spine surgery and compares outcomes in those who engage in the class to a historical group of similar…
- Trial name
- NCT03985436
- Testing
- Trek for Surgical Success
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Sara Davin, PsyD, MPH
Post Operative Pain, Regional Block
PENG and LFCN Block Versus Lumbar Plexus Block for Postoperative Analgesia After Total Hip Arthroplasty
Regional anesthesia for postoperative analgesia in THA includes epidural anesthesia and peripheral nerve blocks. However epidural anesthesia has a great role in THA, it has become restricted as perioperative antithrombotic drugs…
- Trial name
- NCT05652075
- Testing
- pericapsular nerve group and lateral femoral cutaneous nerve block, lumbar plexus block
- Where
- Egypt
- Volunteers
- 66 people
- Sponsor
- Minia University
Spine Degeneration, Spine Disorder
Rate of Bone Union After Surgery With Stand-alone Fibergraft
Some people have back problems caused by degenerative conditions or instability of the spine (eg. Spondylolisthesis). These problems can lead to pain, nerve issues, or difficulties in walking.
- Conditions
- Spine Degeneration, Spine Disorder, Spine Pain, Spine Fusion
- Trial name
- Fibergraft (NCT07199075)
- Testing
- Questionnaires, Computer Tomography
- Where
- Netherlands
- Volunteers
- 80 people
- Sponsor
- AO Innovation Translation Center
Acute Pain Following Decompressive Lumbar Spinal Surgery
The Use of Intrathecal Morphine in the Management of Acute Pain Following Decompressive Lumbar Spinal Surgery
The primary aim of this study is to assess the impact of intrathecal morphine on post-operative pain following instrumented fusion for degenerative lumbar spine disease.
- Trial name
- ITMP (NCT01053039)
- Testing
- Intrathecal Morphine, Intrathecal Saline
- Where
- Canada
- Volunteers
- 150 people
- Sponsor
- University of Calgary
Lower Back Pain
Safety and Performance of the Elaspine System in the Treatment of the Lumbar Spine
The safety and performance of the Elaspine™ Implant System in the treatment of lower back pain will be evaluated with a prospective and nonrandomized, multicenter post-marketing clinical study (PMCS).
- Trial name
- NCT01323543
- Testing
- Elaspine™
- Where
- 5 sites in Germany, Switzerland
- Volunteers
- 40 people
- Sponsor
- Spinelab AG
Postoperative Pain
Lumbar Paravertebral in Hernia Surgery
An inguinal hernia is one of the most common disorders requiring surgical repair in pediatrics. The effective treatment of postoperative pain in infants and children is challenging.
- Trial name
- NCT03408184
- Testing
- Lumbar paravertebral group, The field block group
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Mansoura University
Postoperative Acute Pain, Lumbar Degenerative Diseases
Liposomal Bupivacaine for Pain After Lumbar Fusion
Spine surgery often causes severe postoperative pain. Currently, our hospital routinely uses ropivacaine for local infiltration analgesia (lasting 6-8 hours).
- Trial name
- NCT07171125
- Testing
- Liposomal bupivacaine (local infiltration), ropivacaine (local infiltration)
- Where
- China
- Volunteers
- 204 people
- Sponsor
- Min Li
Back Pain With Radiation, Pain, Postoperative
Spinal Cord Burst Stimulation for Chronic Radicular Pain Following Lumbar Spine Surgery
Spinal cord stimulation (SCS) is a widely applied therapy to treat chronic neuropathic pain, and one of the most common indications is persisting radicular neuropathic pain following lumbar spine surgery.
- Trial name
- NCT03546738
- Testing
- Burst Spinal Cord Stimulation, SCS implant
- Where
- Norway
- Volunteers
- 50 people
- Sponsor
- St. Olavs Hospital
Lumbar Disc Herniation, Radiculopathy Lumbar
Quantitative Sensory Testing and PET/CT Scanning in Assessment of Surgical Outcome for Lumbar Disc Herniation
Patients with lumbar disc herniation suffer from pain and morbidity. Surgical intervention can be a quick and effective relief, however some individuals experience less favorable outcome.
- Trial name
- PET-Pain (NCT03894943)
- Testing
- PET/CT scan, Quantitative Sensory Testing
- Volunteers
- 61 people
- Sponsor
- Spine Centre of Southern Denmark
Lumbar Disc Surgery
Telenursing and Transitional Care
Post-operative care for Lumbar Disc Herniation (LDH) is important to reduce postoperative complications. The transition from hospital to home after discharge is important for LDH patients, as the transition process is flawless…
- Trial name
- NCT06770387
- Testing
- mhealth
- Where
- 4 sites in Turkey (Türkiye)
- Volunteers
- 107 people
- Sponsor
- Hasan Kalyoncu University
Lumbar Disc Disease, Spinal Fusion
Analgesic Effects of Perioperative Propranolol Administration for Spine Surgery
The purpose of this study is to determine if treatment with low-dose oral propranolol in the days before and after surgery decrease postoperative pain and improve pain scores.
- Conditions
- Lumbar Disc Disease, Spinal Fusion, Degenerative Disc Disease
- Trial name
- NCT04421209
- Testing
- Propranolol Hcl 40mg Tab
- Where
- United States
- Sponsor
- Duke University
Lumbar Stenosis, Familial
Sagittal Imbalance and Lumbar Stenosis Surgery: Decompression Without Implant
Lumbar stenosis (LSS) is the most frequent degenerative lumbar disease and is the most frequent indication for spinal surgery. When non-invasive treatments fail, decompression surgery is the gold standard therapy for the majority…
- Trial name
- CLE/EOS (NCT03065452)
- Where
- France
- Volunteers
- 72 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Degenerative Disc Disease, Spondylolisthesis, Lumbar Region
Clinical Effectiveness of Pre-operative Methadone in Single Level Lateral Transpsoas Interbody Fusions
Spinal operations including lumbar fusions for degenerative disorders are becoming more prevalent as the population ages. Inadequate or excessive postoperative analgesia can result in medical comorbidities and prolonged hospital…
- Trial name
- NCT04112550
- Testing
- Methadone Hydrochloride, Oxycodone-Acetaminophen
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- The Methodist Hospital Research Institute
Lumbar Spine Disease
3D Model - Classification of Thoracic and Lumbar Spinal Fractures.
The goal of this clinical trial is to evaluate and compare the effectiveness of a 3D interactive model versus traditional teaching methods in enhancing the teaching of thoracic and lumbar spine fractures classification (AO Spine)…
- Trial name
- NCT06379776
- Testing
- Education through a 3D model, Education through a traditional pedagogical support
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Université Paris-Sud
Lumbar Spondylolisthesis, Lumbar Spine Degeneration
Comparison of Complication Rates Between Initial and Re-operative Anterior Lumbar Interbody Fusion Surgery: Is There a Difference?
To identify the current mortality rate for initial Anterior Lumbar Interbody Fusion(ALIF)procedures. Establish/prove mortality rates for this operation have dropped in the past decade.
- Trial name
- NCT05945550
- Where
- United States
- Volunteers
- 3,500 people
- Sponsor
- Methodist Health System
Lumbar Erector Spinae Plane Block, Pericapsular Nerve Group Block (PENG Block)
Combined Lumbar Erector Spinae Plane Block and Pericapsular Nerve Group Block in Patients Undergoing Hip Surgeries
The investigators are going to evaluate the postoperative analgesic efficacy of combined LESPB and PENG block after hip surgeries.
- Trial name
- NCT05930171
- Testing
- Ultrasound guided L-ESPB and PENG block using Bupivacaine, Postoperative conventional analgesia in form of Acetaminophen
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Menoufia University
Low Back Pain
Modified Thoracolumbar Interfascial Plane Block Versus Erector Spinae Plane Block For Enhancement Of Quality of Recovery After Lumbar Spine Surgery: A Prospective Randomized Controlled Study.
Aim of study The objective of the current study is to compare the efficacy of ultrasound-guided bilateral modified thoracolumbar interfascial plane (TLIP) block versus erector spinae (ES) block in optimizing early quality of…
- Trial name
- NCT07166900
- Testing
- Modified Thoracolumbar Interfascial Plane Block
- Where
- Egypt
- Volunteers
- 64 people
- Sponsor
- Fayoum University