Clinical trials: Lung Cancer Screening, open to volunteers
Thoracic Cancers, Malignant Pleural Mesotheliomas NOS
Evaluation of Cell Changes in Blood and Tissue in Cancers of the Lung, Esophagus and Lung Lining
Background: Chromatin is is the structural building block of a chromosome. It is found inside the nucleus of the cell and consists of a complex of DNA and protein.
- Conditions
- Thoracic Cancers, Malignant Pleural Mesotheliomas NOS, Lung Cancer NOS, Esophageal Cancers NOS
- Trial name
- NCT00242723
- Where
- United States
- Volunteers
- 1,559 people
- Sponsor
- National Cancer Institute (NCI)
Previously Treated Non-Small Cell Lung Cancer
Lung-MAP: A Master Screening Protocol for Previously-Treated Non-Small Cell Lung Cancer
This screening and multi-sub-study randomized phase II/III trial will establish a method for genomic screening of similar large cancer populations followed by assigning and accruing simultaneously to a multi-sub-study hybrid…
- Trial name
- NCT03851445
- Testing
- Screening Platform
- Where
- 1,229 sites in United States
- Volunteers
- 10,000 people
- Sponsor
- SWOG Cancer Research Network
Non Small Cell Lung Cancer, Esophageal Cancer
Tumor Cell and DNA Detection in the Blood, Urine, and Bone Marrow
Patients with resectable solid primary cancers and even limited number of metastases are potentially curable. However, most patients develop recurrences despite surgery.
- Conditions
- Non Small Cell Lung Cancer, Esophageal Cancer, Gastric Cancer, Pancreatic Cancer
- Trial name
- NCT03551951
- Testing
- Test for circulating tumor cells, DNA alterations
- Where
- United States
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Lung Cancer
Association Between Screening Behaviors and Lung Cancer Spectrum
The goal of this observational study is to describe the clinical epidemiological characteristics and disease spectrum distribution of newly diagnosed primary lung cancer patients in a real-world setting.
- Trial name
- NCT07626177
- Where
- China
- Volunteers
- 5,390 people
- Sponsor
- Fudan University
Cancer Screening, Lung Cancer
Precision Navigation to Improve Community Cancer Screening Participation
This study will evaluate whether a precision navigation intervention can help community residents at high risk for cancer complete recommended cancer screening.
- Conditions
- Cancer Screening, Lung Cancer, Breast Cancer, Colorectal Cancer
- Trial name
- NCT07676383
- Testing
- Precision Navigation Intervention, Usual Health Education
- Where
- 3 sites in China
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Hunan Cancer Hospital
Lung Cancer
Next Generation Chest X-Ray Tomosynthesis for Screening of Lung Cancer
The goal of this observational clinical trial is to learn if chest tomosynthesis is a potential alternative to computed tomography for the detection of lung cancer.
- Trial name
- NCT06577883
- Testing
- Chest X-ray Tomosynthesis
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Breast Cancer, Benign Breast Condition
ATUSA Ultrasound Diagnostic Imaging for Breast Lesions Evaluation (AUDIBLE) - iSono Health
AUDIBLE is a multi-site, clinical study conducted in the United States aimed at gathering data on 3D Automated Breast Ultrasound imaging using the iSono Health ATUSA system.
- Conditions
- Breast Cancer, Benign Breast Condition, Breast Fibroadenoma, Breast Neoplasms
- Trial name
- AUDIBLE (NCT07505797)
- Testing
- ATUSA 3D Automated Breast Ultrasound System
- Where
- 2 sites in United States
- Volunteers
- 800 people
- Sponsor
- iSono Health, Inc.
Lung Cancer
Developing Novel Circulating Epigenetic Biomarkers for Early Detection of Lung Cancer
The investigators aim to identify novel circulating methylated biomarkers for early lung cancer detection as well as to develop new technologies that are clinically applicable with high sensitivity and specificity.
- Trial name
- NCT04814407
- Testing
- Blood-derived DNA methylation detection
- Where
- Taiwan
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Lung Cancer, Pulmonary Neoplasm
Rarecells Molecular Biomarkers for Early Detection of Lung Cancer
Early diagnosis of lung cancer is a public health priority. Additionally, early detection of recurrences after treatment is crucial for optimizing disease management.
- Trial name
- BioMolCTC (NCT06546007)
- Testing
- CTC-DNA
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Rarecells Diagnostics SAS
Lung Cancer
Lung Cancer Biomarkers and Screening
RATIONALE: Screening tests that use biomarkers may help doctors find tumor cells early and plan effective treatment for lung cancer. PURPOSE: This clinical trial is studying biomarkers in screening participants for lung cancer.
- Trial name
- NYULCBC (NCT00301119)
- Where
- United States
- Volunteers
- 3,606 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Lung Cancer
Study of Early Cancer Biomarkers in Breath Condensate in Population of Individuals With High-Risk of Lung Cancer Undergoing LDCT Screening.
The trial will evaluate if the newly identified biomarkers of lung cancer in exhaled breath condensate are as a diagnostic tool comparable to the low-dose computer tomography (LDCT) implemented in lung cancer screening recently.
- Trial name
- NCT06016569
- Testing
- Exhaled breath condensate sampling, Blood sampling, LDCT
- Where
- 3 sites in Czechia
- Volunteers
- 3,200 people, healthy volunteers welcome
- Sponsor
- The Institute of Molecular and Translational Medicine, Czech Republic
Lung Cancer Stage IV, Melanoma Stage IV
Screening for Brain Metastases
The survival of patients with CNS metastases often remains limited to some months. CNS metastases are also associated with neurological decline and decrease of quality of life.
- Conditions
- Lung Cancer Stage IV, Melanoma Stage IV, Breast Cancer Metastatic
- Trial name
- GAPIMET (NCT07492121)
- Testing
- gadopiclenol (contrast agent), standard contrast agent
- Where
- Switzerland
- Volunteers
- 180 people
- Sponsor
- University of Zurich
Lung Cancer
Rural Illinois Lung Cancer Screening Initiative
The role of this observational study is to access the feasibility of providing lung cancer screening using a designated nurse navigator through lung cancer screening clinic.
- Trial name
- LDCT (NCT06084078)
- Where
- United States
- Volunteers
- 10,000 people
- Sponsor
- Southern Illinois University
Lung Cancer, Cancer of the Lung
Evaluating the Implementation and Effectiveness of the Pink and Pearl Campaign on Lung Cancer Screening at Christian Hospital
Inspired by the ongoing Pink \& Pearl Campaign, the breast radiology service of Christian Hospital in north St. Louis County will partner with Siteman Cancer Center to pilot this campaign in its mammography clinics in order to…
- Trial name
- NCT07146568
- Testing
- Pink and Pearl Campaign
- Where
- United States
- Volunteers
- 5,515 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Lung Cancer
Health Education Approach to Lung Screening
Evaluate the impact of the patient navigation program on the proportion of patients who complete lung cancer screening (LCS), defined as undergoing a low dose computed tomography (LDCT)
- Trial name
- HEALS (NCT06070870)
- Testing
- Patient Navigation
- Where
- 3 sites in United States
- Volunteers
- 675 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Lung Cancer, Protection Against Malignant Lung Neoplasm (Diagnosis)
Cancer Screening Smoking Cessation AND Respiratory Assessment
The CASSANDRA project (Cancer Screening, Smoking Cessation, AND Respiratory Assessment) is a project led by SEPAR whose main coordinators are Dr. Luis Seijo, a pulmonologist at the Clínica Universitaria de Navarra, and Dr.
- Trial name
- CASSANDRA (NCT06157957)
- Testing
- Lung cancer screening with low dose CT scan
- Volunteers
- 40,000 people, healthy volunteers welcome
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Lung Cancer
Lung Cancer Screening Implementation Project in the Brazilian Public Health Care System (LUSIP)
A prospective, longitudinal, single-arm interventional study of lung cancer screening.
- Trial name
- LUSIP (NCT07279948)
- Where
- Brazil
- Volunteers
- 477 people
- Sponsor
- AstraZeneca
Lung Cancer Patients
SERS-Based Serum Molecular Spectral Detection of Invasive Lung Cancer
Surgery is the main treatment for early lung cancer. It is worth noting that there are significant differences in postoperative prognosis and surgical methods between microinvasive cancer and early-stage invasive cancer.
- Trial name
- NCT06775015
- Testing
- Serum Raman spectroscopy intelligent diagnostic system
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Fuzhou General Hospital