Clinical trials: Lung Cancer Symptoms
Chronic Obstructive Pulmonary Disease, Lung Cancer
Serum, Plasma, DNA and Tissue Bank in Chronic Obstructive Pulmonary Disease and Lung Cancer
A biobank of Serum, plasma, DNA samples together with clinical information including specific questionnaires, complete pulmonary function and chest CT-scan, is prospectively collected in patients seen at the investigators'…
- Trial name
- NCT00858520
- Where
- Belgium
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Lung Cancer
BATTLE-FL: Front-Line Biomarker-Integrated Treatment Study in Non Small Cell Lung Cancer
The goal of this clinical research study is to learn if knowing biomarker status can help researchers find better treatment combinations for patients with advanced NSCLC.
- Trial name
- NCT01263782
- Testing
- Carboplatin, Pemetrexed, Bevacizumab
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- M.D. Anderson Cancer Center
Lung Cancer, Mucositis Oral
Feasibility Study of a Nurse Intervention to Impact Mucositis Severity and Prevent Dehydration
This is a descriptive mixed method pilot study to determine the feasibility of a tailored nurse-delivered telephone intervention designed to impact mucositis symptom severity and prevent dehydration in lung and head/neck cancer…
- Conditions
- Lung Cancer, Mucositis Oral, Dehydration, Head and Neck Cancer
- Trial name
- NCT03416582
- Testing
- Symptom Management Education and Nurse Coaching, Drinks Diary
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of Miami
Metastatic (Stage IV) Non-squamous Non-small Cell Lung Cancer (Nsq-NSCLC) With Driver Gene Negativity, Untreated With Systemic Therapy
Clinical Study on Nanocrystalline Megestrol Acetate for Appetite Improvement and Weight Gain in Pre-Cachexia and Cachexia Stages Key Terminology Analysis
The purpose of this study is to evaluate the efficacy and safety of nanocrystalline medroxyprogesterone acetate for improving appetite and weight gain patients with non-small cell lung cancer (NSCLC) and cachexia and…
- Trial name
- NCT06961188
- Testing
- Nano-crystalline Megestrol Acetate Oral Suspension, Standard Therapy
- Where
- China
- Volunteers
- 174 people
- Sponsor
- Changchun GeneScience Pharmaceutical Co., Ltd.
PONV
Electroacupuncture Plus 5-HT3 Receptor Inhibitor for PONV Prevention in High-Risk Patients Undergoing Thoracoscopic Lung Cancer Surgery
This prospective, randomized controlled study aims to evaluate the efficacy and safety of electroacupuncture combined with 5-HT3 receptor inhibitor for preventing postoperative nausea and vomiting (PONV) in high-risk patients…
- Trial name
- NCT07515027
- Testing
- Prophylactic administration of dolasetron, Electroacupuncture
- Where
- China
- Volunteers
- 204 people
- Sponsor
- Shanghai Chest Hospital
Chronic Pain, Post-thoracotomy Pain Syndrome
Botulinum Toxin A as Treatment for Chronic Postsurgical Pain Following Lung Cancer Surgery
Chronic postsurgical pain following lung cancer surgery is common with and 20-60 % develop chronic pain which persists more than six months after surgery. Causes and health impact of this pain have been comprehensively studied.
- Conditions
- Chronic Pain, Post-thoracotomy Pain Syndrome, Pain, Neuropathic, Pain, Postoperative
- Trial name
- NCT04585620
- Testing
- Onabotulinum Toxin A, Normal saline
- Where
- Denmark
- Volunteers
- 30 people
- Sponsor
- Allan Vestergaard Danielsen, MD
Neoplasms, Pulmonary Disease, Chronic Obstructive
Outlook: An Intervention to Improve Quality of Life in Serious Illness
This study will demonstrate whether an end-of-life preparation and completion intervention reduces anxiety, depression, pain and other symptoms and improves functional status, spiritual well-being, and quality of life.
- Conditions
- Neoplasms, Pulmonary Disease, Chronic Obstructive, Heart Failure, Renal Disease
- Trial name
- NCT00939146
- Testing
- Outlook Attention Control, Outlook Intervention
- Where
- United States
- Volunteers
- 154 people
- Sponsor
- Duke University
Cancer (With or Without Metastasis), Interstitial Lung Disease (ILD)
Hypnosis on Breathlessness Mastery in Patients With Persistent Dyspnea
Persistent dyspnea is a debilitating symptom, that is common and difficult to treat. This symptom is found in many different diseases including chronic obstructive pulmonary disease (COPD), interstitial lung disease (ILD)…
- Conditions
- Cancer (With or Without Metastasis), Interstitial Lung Disease (ILD), Chronic Heart Failure (CHF), COPD
- Trial name
- HYPNEA (NCT07173348)
- Testing
- Hypnosis
- Where
- Switzerland
- Volunteers
- 82 people
- Sponsor
- University Hospital, Geneva
Lung Cancer, Esophageal Cancer
Perspectives of Receiving Open Versus Minimally Invasive Surgery
This study will examine the perspectives of patients' undergoing surgery for lung or esophageal cancer. It will examine both pre-op and post-op patient perspectives and opinions regarding pain and surgical complications.
- Trial name
- PROMIS (NCT01807390)
- Where
- Canada
- Volunteers
- 200 people
- Sponsor
- Ottawa Hospital Research Institute
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) (ICD-10 G93.3)
Munich ME/CFS Cohort Study
The Munich cohort study MUC-CFS aims at the characterization and long-term follow-up of myalgic encephalitis/chronic fatigue syndrome (ME/CFS) in young people aged up to 25 years, as well as at the identification of…
- Trial name
- MUC-CFS (NCT06005246)
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- Technical University of Munich
Lung Cancer
Prospective Study of Active Pain Management in Lung Cancer Outpatients (APM)
This study is: A single-center, randomized, prospective controlled trial. To prove superiority of active pain management group compared to control group by the percent of pain intensity difference of outpatients with lung cancer…
- Trial name
- APM (NCT01310387)
- Testing
- Active pain management
- Where
- South Korea
- Volunteers
- 79 people
- Sponsor
- Chonnam National University Hospital
Lung Cancer
Lung Cancer, Exercise and Force Development
This study evaluates the effectiveness of a supervised one-leg resistance training program in patients with inoperable lung cancer with the primary outcome being rate of force development.
- Trial name
- NCT05778136
- Testing
- Resistance training
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Carcinoma, Non-Small-Cell Lung, Pain, Postoperative
Why in Hospital After VATS Lobectomy
The study aims to identify specific or potential reasons that prolong the length of hospital stay after video-assisted thoracoscopic surgery lobectomy.
- Conditions
- Carcinoma, Non-Small-Cell Lung, Pain, Postoperative, Postoperative Nausea and Vomiting, Infection
- Trial name
- NCT04294108
- Testing
- Prolong in-hospital stay
- Where
- Denmark
- Volunteers
- 160 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Cancer
Exercise Rehabilitation in Veteran Cancer Survivors
Exercise rehabilitation has the potential as a non-pharmacological approach to reduce persistent neuropathic pain in Veterans with lung cancer.
- Trial name
- NCT03621813
- Testing
- Exercise Rehabilitation, Control
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- VA Office of Research and Development
Carcinoma, Non-Small-Cell Lung, Small Cell Lung Carcinoma
A Study of LY4175408 in Participants With Advanced Cancer
The purpose of this study is to measure the safety and efficacy of LY4175408 in participants with selected advanced cancer. In addition, this study will evaluate how much LY4175408 gets into the bloodstream, how it is broken…
- Conditions
- Carcinoma, Non-Small-Cell Lung, Small Cell Lung Carcinoma, Endometrial Neoplasms, Neoplasm Metastasis
- Trial name
- NCT07046923
- Testing
- LY4175408, Pembrolizumab, Carboplatin
- Where
- 27 sites in United States, China and 4 more
- Volunteers
- 240 people
- Sponsor
- Eli Lilly and Company
Stereotactic Body Radiotherapy, 68Ga-MAA
Functional Lung Avoidance Planning Guided by Lung Perfusion PET/CT Versus Anatomical Planning for Lung Stereotactic Body Radiotherapy
Stereotactic body radiotherapy (SBRT) has an increasing role in the treatment of both primary and secondary lung tumors. However, lung SBRT remains associated with significant radiation induced lung injury (RILI).
- Conditions
- Stereotactic Body Radiotherapy, 68Ga-MAA, Lung Cancer (Diagnosis)
- Trial name
- Pegasus 2 (NCT07289646)
- Testing
- Conventional anatomical planning radiotherapy, Functional Lung avoidance planning
- Where
- 2 sites in France
- Volunteers
- 418 people
- Sponsor
- University Hospital, Brest
Lung Cancer (Diagnosis), Lobectomy
A Study to Explore the Early Subjective Evaluation and Objective Recovery in Lung Cancer Patients Undergoing Sublobar Resection Versus Lobectomy
The trial was designed as a single-center, non-interventional, prospective observational study to explore the role of a multimodal digital device in analyzing subjective and objective recovery in lung cancer patients undergoing…
- Conditions
- Lung Cancer (Diagnosis), Lobectomy, Sublobar Resection
- Trial name
- NCT07288710
- Where
- China
- Volunteers
- 316 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Cancer, Heart Failure
Telepalliation - Digital Platform for Patients in Palliation and Their Relatives
This project has focus on patients in palliation testing a digital platform TelePal.dk.
- Conditions
- Cancer, Heart Failure, Chronic Obstructive Pulmonary Disease, Neurological Diseases
- Trial name
- NCT04995848
- Testing
- Telepalliation
- Where
- Denmark
- Volunteers
- 182 people
- Sponsor
- Aalborg University
Cardiotoxicity, Lung Cancer Stage III
Cardiotoxicity in Locally Advanced Lung Cancer Patients Treated With Chemoradiation Therapy
This observational cohort will evaluate the cardiovascular effects of chemoradiation used to treat locally advanced, non-small cell lung cancer.
- Conditions
- Cardiotoxicity, Lung Cancer Stage III, Lung Cancer Stage II, Radiation Toxicity
- Trial name
- CLARITY (NCT04305613)
- Testing
- Chemoradiation
- Where
- 8 sites in United States
- Volunteers
- 221 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
Non-Small Cell Lung Cancer
Study of Alimta® (Pemetrexed) Plus VELCADE® (Bortezomib) or Alimta Alone or VELCADE Alone in Patients With Locally Advanced or Metastatic Non-Small Cell Lung Cancer Who Have Failed Prior Therapy
The purpose of this study is to establish the objective response rate (complete response + partial response), following treatment with Alimta plus VELCADE, Alimta alone, or VELCADE alone in patients with locally advanced or…
- Trial name
- NCT00343720
- Testing
- VELCADE, Alimta
- Where
- Belgium
- Sponsor
- Millennium Pharmaceuticals, Inc.
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