Clinical trials: Lung Cancer Symptoms
Lung Cancer, Robotic Thoracic Surgery
Impact of Robotic Approach Compared to VATS and Open Approach on Quality of Life in Patients With Lung Cancer
The aim of the study is to compare quality of life and early and late post-operative pain after anatomical lung resection (lobectomy or segmentectomy) performed by a robotic approach compared to the videothoracoscopic approach…
- Conditions
- Lung Cancer, Robotic Thoracic Surgery, Video-assisted Thoracis Surgery (VATS), Open Thoracotomy Surgery
- Trial name
- QoL (NCT04353349)
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- Istituto Clinico Humanitas
Cancer, Lung, Metastasis
Feasibility Study of Personalized Ultra-fractionated Stereotactic Ablative Radiotherapy (PULSAR) for Cancers of the Central Lung
The objective of this study is to enhance the safety profile of SAbR in ultra-central tumors of the lung (primary or metastatic) without compromising its effectiveness.
- Trial name
- NCT06712745
- Testing
- Personalized Ultra-fractionated stereotactic ablative radiotherapy (PULSAR)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Texas Southwestern Medical Center
Breast Neoplasms, Ovarian Neoplasms
Study of Motexafin Gadolinium and Docetaxel for Advanced Cancer
The primary purpose of this study is to evaluate the safety, side effects, and dosage for Motexafin Gadolinium given with the chemotherapy drug docetaxel to patients with advanced cancers.
- Conditions
- Breast Neoplasms, Ovarian Neoplasms, Prostatic Neoplasms, Lung Neoplasms
- Trial name
- NCT00120939
- Testing
- Motexafin Gadolinium
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Pharmacyclics LLC.
Chronic Obstructive Pulmonary Disease, Lung Cancer
Accelerated Pulmonary Rehabilitation in the Preoperative Period
This proposed project will be a single arm, non-masked study. Participants who are actively smoking with a diagnosis of a new lung nodule, either confirmed or suspicious for lung cancer, with a plan for lung cancer treatment with…
- Trial name
- PREHAB (NCT06432972)
- Testing
- Pulmonary Rehab
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Vermont
Heart Failure, Pulmonary Disease
Caregiver Outlook: An Intervention to Improve Caregiving in Serious Illness
Informal caregivers provide a majority of care for patients during serious illness. Lack of preparation and completion may leave caregivers less capable of caring for a loved one or making crucial decisions influencing care.
- Conditions
- Heart Failure, Pulmonary Disease, Cancer
- Trial name
- NCT01672294
- Testing
- Preparation and life completion, Attention Control
- Where
- United States
- Volunteers
- 286 people
- Sponsor
- VA Office of Research and Development
Carcinoma, Non-Small-Cell Lung, Depression
Efficacy and Safety Analyses of Mirtazapine in NSCLC Patients With Depression
This is a phase II, placebo-controlled, randomized, double-blinded clinical trial. Study objective is to assess the efficacy and safety of mirtazapine in advanced NSCLC patients with malignant tumor related depression.
- Trial name
- NCT02650544
- Testing
- Mirtazapine
- Where
- China
- Volunteers
- 236 people
- Sponsor
- Sun Yat-sen University
Lung Cancer
Effects of Palliative Care on Quality of Life and Symptom Control in Patients With Stage IIIB or Stage IV Non-Small Cell Lung Cancer That Cannot Be Removed by Surgery
RATIONALE: Palliative care may be more effective than standard care in improving quality of life and symptoms in patients with lung cancer.
- Trial name
- NCT00823732
- Testing
- educational intervention, medical chart review, questionnaire administration
- Where
- United States
- Volunteers
- 280 people
- Sponsor
- City of Hope Medical Center
Segmentectomy
Comparison of Energy Instruments and Stapling Device to Dissect Intersegmental Plane in Segmentectomy
According to published studies, there are two main approaches in the dissection of intersegmental plane: stapling devices and energy instrument separation.
- Trial name
- NCT03192904
- Testing
- Energy Instruments, Stapling Device
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Ruijin Hospital
Lung Cancer
The Effect of Mindfulness-Based Breathing Exercises on Dyspnea, Symptom Control, and Quality of Life in Lung Cancer Patients Undergoing Chemotherapy
This research is designed to determine the effect of mindfulness-based breathing exercises on dyspnea, symptom control, and quality of life in lung cancer patients undergoing chemotherapy.
- Trial name
- NCT07520799
- Testing
- Mindfulness-Based Breathing Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Firat University
Fiberoptic Bronchoscopy (FOB), Lung Cancer (Diagnosis)
Nebulized Lidocaine And Ketamine Before Fiberoptic Bronchoscopy
The current study is looked for the comparison between nebulized lidocaine and ketamine, nebulized lidocaine, and usual lidocaine spray in the oral and nasal cavities before flexible bronchoscopy.
- Conditions
- Fiberoptic Bronchoscopy (FOB), Lung Cancer (Diagnosis), Premedication
- Trial name
- NCT07743333
- Testing
- Nebulized lidocaine and ketamine, Nebulized Lidocaine, Lidocaine spray (2%)
- Where
- Egypt
- Volunteers
- 134 people
- Sponsor
- Alexandria University
Non-Small Cell Lung Cancer
Enoxaparin Low Molecular Weight Heparin (LMWH) in Advanced Non Small Cell Lung Cancer: Effect on Survival and Symptom Control in Patients Undergoing First Line Chemotherapy (SYRINGES)
Rationale: a number of recent phase III randomized trials have shown a survival benefit of a treatment with subcutaneous low-molecular weight heparin in patients with advanced solid malignancies.
- Trial name
- SYRINGES (NCT00771563)
- Testing
- cisplatin + docetaxel, cisplatin + docetaxel + enoxaparin
- Where
- 2 sites in Belgium
- Volunteers
- 104 people
- Sponsor
- University Hospital, Antwerp
Anaplastic Lymphoma Kinase (ALK)- Positive Tumors, Non-small Cell Lung Cancer (NSCLC)
Managed Access Programs for LDK378, Ceritinib
The purpose of this registration is to list Managed Access Programs (MAPs) related to LDK378, Ceritinib.
- Trial name
- NCT05100134
- Testing
- ceritinib
- Sponsor
- Novartis Pharmaceuticals
Non-small-Cell Lung Carcinoma
Trial of Neoadjuvant Docetaxel and Cisplatin for Resectable Non-Small Cell Lung Cancer
The primary objective of this study is to assess the response rate of treatment with two cycles of cisplatin and docetaxel chemotherapy prior to surgery (neoadjuvant) for early stage non-small cell lung cancer (NSCLC).
- Trial name
- NCT00232206
- Testing
- Neoadjuvant Therapy with Cisplatin Plus Docetaxel
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Providence Health & Services
Advanced Cancer
Outcomes of Triaged Family Care in Advanced Cancer
The purpose of this study is to assess the quality of life of patients with advanced cancer and their family caregivers and to evaluate two doses of a family-based program of care versus control.
- Trial name
- FOCUS-Triage (NCT00709176)
- Testing
- Brief FOCUS Program, Extensive FOCUS Program
- Where
- 5 sites in United States
- Volunteers
- 484 people
- Sponsor
- University of Michigan
Lung Cancer, Metastatic Cancer
Whole-Brain Radiation Therapy and Pemetrexed in Treating Patients With Brain Metastases From Non-Small Cell Lung Cancer
RATIONALE: Radiation therapy uses high-energy x-rays to kill tumor cells. Pemetrexed may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.
- Trial name
- NRR (NCT00280748)
- Testing
- pemetrexed disodium, radiation therapy
- Where
- 2 sites in United States
- Volunteers
- 10 people
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Advanced Cancer, Chronic Obstructive Pulmonary Disease (COPD)
Improving Clinician Communication Skills (ICCS)
This research study is a randomized trial to evaluate a training program that is designed to improve the communication skills of clinicians.
- Conditions
- Advanced Cancer, Chronic Obstructive Pulmonary Disease (COPD), Restrictive Lung Disease, Congestive Heart Failure
- Trial name
- ICCS (NCT00687349)
- Testing
- Training Program Intervention
- Where
- 4 sites in United States
- Volunteers
- 6,086 people
- Sponsor
- University of Washington
Chemotherapy-induced Nausea and Vomiting, Lung Cancer
Olanzapine for the Prevention and Treatment of Nausea and Vomiting Induced by Chemotherapy of Lung Cancer
Chemotherapy induced nausea and vomiting (CINV) is a common adverse effect in treatment of cancer, which influences the quality of life and adherence to treatment of patients and leads to dehydration, malnutrition and even death.
- Trial name
- NCT03571126
- Testing
- Olanzapine
- Where
- 2 sites in China
- Volunteers
- 156 people
- Sponsor
- Zunyi Medical College
Lung Cancer (Diagnosis)
A Multicenter, Prospective Study on the Diagnostic Efficacy of Femtosecond Laser Label-Free Imaging Combined With Artificial Intelligence-Assisted Diagnosis for Rapid Diagnosis of Lung Cancer Surgical Specimens
To investigate the diagnostic efficacy of Femtosecond Laser Label-Free Imaging combined with artificial intelligence-assisted diagnosis for rapid diagnosis of lung cancer.
- Trial name
- NCT07794449
- Testing
- Femtosecond Laser Label-Free Imaging Combined with Artificial Intelligence
- Volunteers
- 335 people
- Sponsor
- Shanghai Zhongshan Hospital
Non-Small Cell Lung Cancer
20-Fr Versus 24-Fr Chest Drains After Uniportal VATS Lobectomy for NSCLC
This randomized clinical trial compared two different chest drain sizes, 20 Fr and 24 Fr, in patients undergoing lung lobectomy for lung cancer.
- Trial name
- DRAIN2024 (NCT07827885)
- Testing
- 20-Fr Thoracic Drain, 24-Fr Thoracic Drain
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- Fondazione Policlinico Universitario Campus Bio-Medico
Advanced Lung Cancer
A Clinical Study of Pain and Discomfort Associated With Advanced Lung Cancer
In this research, the patients with advanced lung cancer accompanied by pain and discomfort were treated by injecting freshly manufactured tissue permeable hyaluronan fragment HA35 into the tissue under abdominal adipose.
- Trial name
- NCT05852002
- Testing
- 35 kDa hyaluronan fragment
- Where
- Mongolia
- Volunteers
- 10 people
- Sponsor
- Nakhia Impex LLC
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