Clinical trials: Lung Compliance
Non-Small Cell Lung Carcinoma, Compliance Behavior
Patient Navigation for Lung Cancer Screening in an Urban Safety-Net System
The study proposes to evaluate a patient navigation intervention among a sample of 446 individuals referred for CT-based lung cancer screening in an urban safety-net setting.
- Conditions
- Non-Small Cell Lung Carcinoma, Compliance Behavior, Prevention Harmful Effects
- Trial name
- NCT02758054
- Testing
- Patient Navigation
- Where
- United States
- Volunteers
- 447 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Multiple Sclerosis, Long Covid
Fatigue Investigation Using Digital Outcomes
This study investigates objective methods to measure and monitor fatigue in patients with post-COVID-19 condition (long COVID) and multiple sclerosis (MS), and includes a group of healthy volunteers for comparison.
- Conditions
- Multiple Sclerosis, Long Covid, Healthy
- Trial name
- FIDO (NCT07783074)
- Where
- 6 sites in Switzerland
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Liliana Barrios
Covid19, Health Care Seeking Behavior
New Jersey Healthcare Essential Worker Outreach and Education Study - Testing Overlooked Occupations
This mixed methods study evaluates the effectiveness and cost of a healthcare worker focused outreach intervention strategy versus community organization led outreach to explore contextual factors (individual, family, and…
- Conditions
- Covid19, Health Care Seeking Behavior, Health Behavior
- Trial name
- NCT04766333
- Testing
- Healthcare Worker Focused Outreach, Community Organization Led Outreach
- Where
- United States
- Volunteers
- 2,017 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
COVID-19, Vaccine
Connecting Friends and Health Workers to Boost COVID-19 Vaccination in Latino Communities
The goal of this clinical trial is to find out which approach works better in getting more of the friends and connections of Latino adults get vaccinated against COVID-19. The main questions this study aims to answer are: 1.
- Trial name
- REDES (NCT06128928)
- Testing
- REDES, Control
- Where
- United States
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Covid19, Vaccine Refusal
Use of Construal Level Theory to Inform Messaging to Increase Vaccination Against COVID-19
This study aims to increase uptake of the COVID booster vaccine through messaging informed by Construal Level Theory. Patients in the Mass General Brigham (MGB) health system aged 18 and older who are eligible for the COVID…
- Trial name
- NCT04871776
- Testing
- Messaging informed by construal level theory, Usual Care
- Where
- United States
- Volunteers
- 3,671 people
- Sponsor
- Brigham and Women's Hospital
Asthma, Obesity
Reducing Socioeconomic Disparities in Health at Pediatric Visits
This research project is aimed to assess the effectiveness and impact of a pediatric-based intervention aimed at reducing low-income families' unmet material needs (food, housing, employment, childcare, household heat, education…
- Conditions
- Asthma, Obesity, Health Care Utilization, Health Care Disparities
- Trial name
- WECARE01 (NCT02451059)
- Testing
- WE CARE survey, WE CARE Community Resource Handout, Patient Navigator
- Where
- 6 sites in United States
- Volunteers
- 1,205 people
- Sponsor
- Boston Medical Center
Bronchopulmonary Dysplasia, Pulmonary Hypertension Due to Lung Diseases and Hypoxia
Ventilator Pressure and Optimization of Compliance and Hemodynamics
In preterm infants < 34 weeks' gestation at birth receiving respiratory support with invasive positive pressure ventilation, the positive end-expiratory pressure (PEEP) of best compliance will increase the cardiac output and…
- Conditions
- Bronchopulmonary Dysplasia, Pulmonary Hypertension Due to Lung Diseases and Hypoxia, Extreme Prematurity, Ventilator Lung; Newborn
- Trial name
- VPOCH (NCT06512935)
- Testing
- Increase in the PEEP followed by decrease in the PEEP, Decrease in the PEEP followed by increase in the PEEP
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Alabama at Birmingham
Wellness, Burnout, Caregiver
Evaluating the Impact of Resource Navigators to Support LTC and RH Staff During and Beyond COVID-19
The goal of this clinical trial is to test how well resource navigators help long-term care and retirement home staff access the various health and wellness resources available to them and the effects that this has on their…
- Conditions
- Wellness, Burnout, Caregiver, Burnout, Professional, COVID-19
- Trial name
- NCT05677997
- Testing
- Intervention
- Where
- Canada
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Health Behavior, Health Care Utilization
RADx-UP Phase 3D (Oregon Saludable: Juntos Podemos)
The ongoing Oregon Saludable: Juntos Podemos (OSJP, Healthy Oregon: Together We Can) project was developed to directly address the COVID-19 related health disparities among Latinx communities through community engagement funded…
- Conditions
- Health Behavior, Health Care Utilization, Vaccine Hesitancy
- Trial name
- NCT05910879
- Testing
- Self-Affirmation Implementation Intentions (SAII) Intervention, Promotores de Salud (Health Education)
- Where
- United States
- Volunteers
- 625 people
- Sponsor
- University of Oregon
Cystic Fibrosis, Cystic Fibrosis Liver Disease
Real World Clinical Outcomes With Novel Modulator Therapy Combinations in People With CF (RECOVER)
RECOVER is a prospective, multicenter observational study designed to measure the real world clinical effectiveness of elexacaftor/tezacaftor/ivacaftor (ETI) triple combination therapy in people with cystic fibrosis initially…
- Conditions
- Cystic Fibrosis, Cystic Fibrosis Liver Disease, Cystic Fibrosis in Children, Adherence, Medication
- Trial name
- RECOVER (NCT04602468)
- Testing
- Elexacaftor/Tezacaftor/Ivacaftor
- Where
- 7 sites in Ireland, United Kingdom
- Volunteers
- 206 people
- Sponsor
- Royal College of Surgeons, Ireland
Medication Adherence, Asthma
AdheRence to Inhaled Corticosteroids in Asthma
It is widely recognized that asthma in adult African American patients is a significant health problem, which is partly affected by relatively low inhaled corticosteroid (ICS) adherence rates.
- Trial name
- ARICA (NCT03769519)
- Testing
- ARICA
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Duke University
Sepsis, ARDS
The Effect of Positive End Expiratory Pressure on Central Venous Pressure Among Patients With Different Lung Compliance
To observe the effect of PEEP on CVP among patients with different respiratory compliance
- Conditions
- Sepsis, ARDS, Traumatic Brain Injury
- Trial name
- NCT03341572
- Testing
- 5,10 and 15cmH2O positive end expiratory pressure
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Jingyuan,Xu
Vaccine Refusal, Covid19
Project 2VIDA! COVID-19 Vaccine Intervention Delivery for Adults in Southern California
The United States (U.S.) is the country with the largest number of infections and deaths due to COVID- 19 and racial/ethnic minorities are disproportionately affected.
- Trial name
- 2VIDA! (NCT05022472)
- Testing
- COVID-19 Individual Awareness and Education., COVID-19 Community Outreach & Health Promotion., COVID-19 Individual Health Education & Linkages to Medical and Supportive Services.
- Where
- 6 sites in United States
- Volunteers
- 1,051 people, healthy volunteers welcome
- Sponsor
- Britt Skaathun
Elderly Women
Telerehabilitation on Physical and Mental Health of the Elderly in the Covid-19 Pandemic Context
Introduction: Due to the COVID-19 pandemic scenario, social distancing has become the main strategy to contain this pandemic, causing negative impacts on the physical and mental health of the elderly population.
- Trial name
- NCT05465811
- Testing
- Program of physical exercises and health education by telerehabilitation
- Where
- Brazil
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Paulista University
Non Small Cell Lung Cancer
Bevacizumab Plus Chemotherapy for Advanced Non Small Cell Lung Cancer Patients as 1st Line Treatment
Investigators propose to assess, retrospectively and prospectively the safety and tolerability profile (number of participants with adverse events) of standard chemotherapy and anti-angiogenic agent bevacizumab (Avastin) as first…
- Trial name
- NCT01934465
- Where
- 8 sites in Greece
- Volunteers
- 300 people
- Sponsor
- Hellenic Oncology Research Group
Severe Asthma, Asthma
Digital Self-Monitoring in Severe Asthma
This randomized controlled pilot study aimed to assess adherence to telemedicine-based home monitoring using the AioCare digital respiratory system in adults with severe asthma over a three-month period and to determine whether…
- Trial name
- NCT07393984
- Testing
- AioCare home spirometry system
- Where
- Romania
- Volunteers
- 30 people
- Sponsor
- University of Medicine and Pharmacy "Victor Babes" Timisoara
Adherence, Treatment
High-Flow in Hypercapnic Stable COPD Patients
Monocentric, prospective, open, randomized 1:1, controlled study to evaluate the impact of nasal high-flow (NHF) on nocturnal transcutaneous PCO2 (PtCO2) compared to non-invasive ventilation ± Long-Term Oxygen Therapy (LTOT) in…
- Trial name
- HIGH-FLOW (NCT04281316)
- Testing
- Nasal High Flow installation, Non Invasive Ventilation, Training session
- Where
- France
- Volunteers
- 3 people
- Sponsor
- University Hospital, Grenoble
Mechanical Ventilation
Sigh in Pressure Support Ventilation to Detect Respiratory System Compliance and Lung Recruitability
The goal of this physiological study is to determine whether ventilator-delivered sigh breaths during pressure support ventilation (PSV) provide a reliable bedside index of lung recruitability and can guide PEEP optimization.The…
- Trial name
- NCT07172061
- Testing
- PSV + sigh (Clinical PEEP and Clinical PEEP + 3 cmH₂O)
- Where
- 2 sites in Italy
- Volunteers
- 110 people
- Sponsor
- AUSL Romagna Rimini
Chronic Obstructive Pulmonary Disease (COPD)
Soins intégrés BPCO (Broncho-pneumopathie Chronique Obstructive) en Valais - Mieux Vivre Avec ma BPCO (COPD Integrated Care Program Valais - Living Well With COPD)
Background: Chronic obstructive pulmonary disease (COPD) is a progressive respiratory disorder characterized by acute exacerbations that contribute to physical impairment and increased healthcare use and costs.
- Trial name
- NCT02001922
- Testing
- COPD integrated care
- Where
- Switzerland
- Volunteers
- 57 people
- Sponsor
- Centre Hospitalier du Centre du Valais
Cystic Fibrosis in Children
The Effect of Telenursing on Self-efficacy and Treatment Adherence in Children With Cystic Fibrosis
The goal of this clinical trial is to learn if a telenursing-based programs works to increase self-efficacy and treatment adherence in children with Cystic fibrosis disease.
- Trial name
- NCT06660745
- Testing
- telenursing-based family empowerment program
- Where
- Iran
- Volunteers
- 50 people
- Sponsor
- Shahid Beheshti University of Medical Sciences