Clinical trials: Lung Edema
Heart Failure, Congestive
Using Magnetic Resonance Imaging to Predict People Who Are Likely to Develop Flash Pulmonary Edema (The PREDICT Study)
Flash pulmonary edema is a sudden, abnormal build-up of fluid in the lungs. It is usually caused by heart failure and can be life threatening.
- Trial name
- PREDICT (NCT00542503)
- Where
- United States
- Volunteers
- 579 people
- Sponsor
- Wake Forest University Health Sciences
Postoperative Pneumonia, Postoperative Pulmonary Atelectasis
Intravenous Lidocaine Infusion Reduce Postoperative Pulmonary Complications in Patients Undergoing Minimally Invasive Esophagectomy
The goal of this double-center, double-blind, randomized controlled clinical trial is to compare the effect of intravenous lidocaine infusion on postoperative pulmonary complications in patients undergoing minimally invasive…
- Conditions
- Postoperative Pneumonia, Postoperative Pulmonary Atelectasis, Postoperative Pulmonary Edema
- Trial name
- NCT06138041
- Testing
- intravenous lidocaine infusion, Saline
- Volunteers
- 770 people
- Sponsor
- Sichuan Cancer Hospital and Research Institute
Fluid Overload
Ultrasound Lung Fluid Responsiveness During Hysterectomy
Bedside lung ultrasound can detect pulmonary congestion by detecting the appearance of B-lines. Pulmonary edema may occur even without cardiomyopathy or heart failure, especially after excessive fluid administration.
- Trial name
- NCT03429751
- Testing
- 30 ml/Kg/h crystalloid, 10 ml/Kg/h crystalloid
- Where
- Egypt
- Volunteers
- 48 people
- Sponsor
- Alaa Mazy
High Altitude Pulmonary Edema
Susceptibility to High Altitude Pulmonary Edema in Subjects With Increased Hypoxic Pulmonary Vasoconstriction
It has been shown, that subjects susceptible to high altitude pulmonary edema (HAPE)are characterized by an abnormal increase of pulmonary artery pressure at rest in hypoxia and during exercise in normoxia.
- Trial name
- NCT00559442
- Testing
- Altitude Exposure:
- Where
- Germany
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Heidelberg University
High Altitude Pulmonary Hypertension, Sleep Apnea
Sleep Related Breathing Disturbances and High Altitude Pulmonary Hypertension in Kyrgyz Highlanders
High altitude pulmonary hypertension, a form of altitude illness that occurs in long-term residents at altitudes >2500 m, is characterized by dyspnea, hypoxemia, impaired exercise performance and hypertension in the pulmonary…
- Trial name
- NCT01621061
- Where
- Kyrgyzstan
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Obstructive Sleep Apnea, Pulmonary Edema Cardiac Cause
Obstructive Sleep Apnea Treatment on Cardiovascular Events in Patients With Acute Cardiogenic Pulmonary Edema: CPAP-CARE STUDY.
Despite the advances in the treatment of acute cardiogenic pulmonary edema (ACPE), the readmissions rates and cardiovascular events remain very high.
- Trial name
- CPAP-CARE (NCT03936751)
- Testing
- CPAP, Nasal Strips
- Where
- 4 sites in Brazil
- Volunteers
- 150 people
- Sponsor
- University of Sao Paulo
Respiration Failure, Cardio Vascular Disease
COMPARE-VENT Feasibility Pilot Study
Cardiac disease complicated by respiratory insufficiency comprises the most frequent indication for cardiac intensive care unit (CICU) admission, with nearly one-third patients requiring advanced respiratory support and over 20%…
- Conditions
- Respiration Failure, Cardio Vascular Disease, Cardiogenic Pulmonary Oedema, Critical Illness
- Trial name
- NCT07656259
- Testing
- Volume Controlled Mode, Pressure Controlled Mode
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Mayo Clinic
High Altitude Pulmonary Hypertension
Inhaled Nitric Oxide for High Amplitude Pulmonary Edema (HAPE)
High Altitude Pulmonary Edema (HAPE) is a critical, non-cardiogenic pulmonary edema that manifests in high-altitude conditions, marked by the rapid onset of symptoms such as dyspnea, cough, frothy sputum, and cyanosis.
- Trial name
- HAPE (NCT06852924)
- Testing
- Nitric Oxide Generation and Delivery System
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Novlead Inc.
Dyspnea, Paroxysmal, Heart Failure, Left Sided
Management of Cardiogenic Pulmonary Edema (RENAU-OAP)
The prevalence of heart failure is estimated to 2.3 percent of the adult population and strongly increases with age, according to french disability-health surveys.
- Trial name
- RENAU-OAP (NCT03148847)
- Testing
- Baseline care, Referential's dissemination
- Where
- France
- Volunteers
- 859 people
- Sponsor
- Centre Hospitalier Annecy Genevois
Heart Failure, Congestive, Dyspnea
The DIAMOND Study: Distensibility Improvement And Remodeling in Diastolic Heart Failure
The purpose of this study is to test the hypothesis that treatment with oral ALT-711 twice daily for 16 weeks will improve aortic distensibility, exercise tolerance, and quality of life in elderly patients with isolated diastolic…
- Conditions
- Heart Failure, Congestive, Dyspnea, Pulmonary Edema
- Trial name
- NCT00043836
- Testing
- ALT-711
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- Synvista Therapeutics, Inc
Lung Edema, Hip Fractures
Ultrasound in Evaluation of Preoperative Fluid Management of Hip Fracture Surgery Patients
Goal directed fluid therapy is a new standard surgical procedure which is successful in patients undergoing hip revision arthroplasty, There has been a reduction of postoperative complications, most importantly surgery with a…
- Trial name
- NCT05916599
- Testing
- ultrasound
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Gaziosmanpasa Research and Education Hospital
High Altitude Pulmonary Edema, Non-Invasive Positive Pressure Ventilation
Non-Invasive Positive Pressure Ventilation Management of High Altitude Pulmonary Edema
Trial of Non-Invasive Positive Pressure Ventilation Management of High Altitude Pulmonary Edema
- Conditions
- High Altitude Pulmonary Edema, Non-Invasive Positive Pressure Ventilation, Hypoxia
- Trial name
- NCT04288219
- Testing
- Non-Invasive Positive Pressure Ventilation, Nifedipine, supplemental oxygen
- Where
- Nepal
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Heart Failure
Mechanically Optimizing Cardiac Preload in Heart Failure Patients
The purpose of the current study is to determine if partial balloon occlusion of the inferior vena cava can optimize cardiac pre-load and subsequently pulmonary pressures and cardiac output as a novel method to unload pulmonary…
- Trial name
- NCT04338503
- Testing
- Partial IVC occlusion
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Cardioflow Technologies, LLC
Covid19
Chest Radiography in COVID-19 Patients
To assess the prognostic performance of the RALE score with respect to duration of ventilation, and to describe changes in the RALE score over time.
- Trial name
- NCT04485338
- Where
- Netherlands
- Volunteers
- 139 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)