Clinical trials: Lung Function Testing
Scleroderma, Systemic, Lung Diseases, Interstitial
Functional Exercise Tests in Patients With Systemic Sclerosis
The aim of the study is to examine the validity of peripheral oxygen saturation measurement during the 6-minute walk test in patients with Systemic Sclerosis (SSc) and to examine the utility of two other functional tests as…
- Conditions
- Scleroderma, Systemic, Lung Diseases, Interstitial, Pulmonary Arterial Hypertension, Acroosteolysis
- Trial name
- NCT04650659
- Testing
- 6-minute walk test part one, 6-minute walk test part two, 1-minute sit-to-stand test
- Where
- Denmark
- Volunteers
- 83 people
- Sponsor
- University of Aarhus
Covid19, Exercise
Inspiratory Muscle Training in COVID-19 Patients
This study aims to investigate whether adjunctive inspiratory muscle training (IMT) can enhance the benefits of pulmonary rehabilitation (PR) in patients with COVID-19.
- Trial name
- ADDIMTCOVID (NCT04595097)
- Testing
- inspiratory muscle traiing
- Where
- Brazil
- Volunteers
- 138 people
- Sponsor
- Escola Superior de Ciencias da Saude
Cystic Fibrosis
Effects of a 6-Months Physical Conditioning Program in Patients With Cystic Fibrosis
The purpose of this randomized, controlled trial was to determine whether a (and if so which) physical conditioning program is effective to improve health status, physical activity, and quality of life in patients with cystic…
- Trial name
- NCT00231686
- Testing
- Supervised aerobic training, Supervised strength training, Unsupervised training
- Where
- 4 sites in Germany, Switzerland
- Volunteers
- 80 people
- Sponsor
- Julius-Maximilians University
ALS
Remote Pulmonary Function Testing in Amyotrophic Lateral Sclerosis (Pilot)
The specific objective of this study is to validate the practice of remote pulmonary function testing (rPFT) conducted in the home through the use of connected mobile health devices and the Penn State Hershey ALS Telemanagement…
- Trial name
- NCT03214224
- Testing
- remote pulmonary function testing, standard pulmonary function testing
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Cystic Fibrosis
Modeling of Chest Physiotherapy Using Impedance Measurements (PHYSIOMOD)
"The usefulness of respiratory physiotherapy and its execution modalities remains highly debated even though reviews of the literature show that respiratory physiotherapy is able to improve the drainage of bronchial secretions…
- Trial name
- PHYSIOMOD (NCT04094441)
- Testing
- chest physiotherapy
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Muscle Soreness, Exercise
Effects of Delayed Muscle Pain on Respiratory Muscle Function
The aim of the study was to determine whether delayed-onset muscle soreness (DOMS) in trunk muscles has an effect on respiratory function parameters, respiratory muscle strength, respiratory muscle endurance, and exercise…
- Conditions
- Muscle Soreness, Exercise, Respiratory Muscles, Respiratory Function Tests
- Trial name
- NCT05276986
- Testing
- DOMS protocol
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Ankara Yildirim Beyazıt University
Lung Neoplasms, Emphysema
Computed Tomography Assessment of Regional Ventilation (CURVE)
This study uses CT scans to assess airflow in the lung, the scan is quick, cheap and painless. The information from the scan may help doctors tell which patients are suitable to have surgery to cure early stage lung cancer.
- Conditions
- Lung Neoplasms, Emphysema, Lung Diseases, Interstitial, Pulmonary Disease, Chronic Obstructive
- Trial name
- CURVE (NCT02879773)
- Testing
- CTPVe
- Where
- United Kingdom
- Volunteers
- 131 people
- Sponsor
- Heart of England NHS Trust
Forward Head Posture
Thoracic Expansion vs DNS Exercises in Forward Head Posture
This randomized controlled trial aims to compare the effects of thoracic expansion exercises and Dynamic Neuromuscular Stabilization (DNS) on respiratory function and bilateral trapezius muscle activity in individuals with…
- Trial name
- FHP-DNS-TE (NCT07238660)
- Testing
- Dynamic Neuromuscular Stabilization Exercises, Thoracic Expansion Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Esra BECENI
Anesthesia, Geriatric Patients
The Effect of Anesthesia Type on Pulmonary Function
The role of neuraxial anesthesia in preventing respiratory complications is a controversial in elderly patients. The aim of the study was to evaluate the benefits of neuraxial anesthesia on pulmonary function during…
- Trial name
- NCT03399201
- Testing
- General anesthesia, Neuraxial anesthesia, Spirometer
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Tokat Gaziosmanpasa University
Respiration Disorders
Epidural Analgesia and Postoperative Respiratory Functions (EPAPRES)
Patients operated with posterolateral thoracotomy were enrolled. Post-operative analgesia was provided either by TEA with 0.1% bupivacaine or pethidine based intravenous analgesia (IVA) in our sample population.
- Trial name
- EPAPRES (NCT03643757)
- Testing
- Thoracic epidural analgesia, Bupivacaine
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Yedikule Training and Research Hospital
COVID-19 Pneumonia, Sequelae of; Infection
Assessment of Long-term Sequelae of Coronavirus Disease 2019 (COVID-19) Pneumonia With Chest CT and Pulmonary Function Tests
The goal of this prospective multicentric study is to evaluate the presence of long-term pulmonary sequelae in patients who had required hospitalization for treating COVID-19 pneumonia, trough chest CT and pulmonary function…
- Conditions
- COVID-19 Pneumonia, Sequelae of; Infection, Respiratory Function Impaired, SARS CoV 2 Infection
- Trial name
- NCT05835128
- Where
- 2 sites in Portugal
- Volunteers
- 250 people
- Sponsor
- Centro Hospitalar Universitario do Algarve
Tuberculosis
Early Risk Assessment in Household Contacts (≥10 Years) of TB Patients by New Diagnostic Tests in 3 African Countries
The ERASE - TB study will be conducted in order to fill a critical unmet need for tuberculosis control. Persons who are in contact with an infectious TB case may become infected themselves.
- Trial name
- ERASE-TB (NCT04781257)
- Testing
- New test candidates
- Where
- 3 sites in Mozambique, Tanzania and 1 more
- Volunteers
- 2,100 people, healthy volunteers welcome
- Sponsor
- Michael Hoelscher
Postoperative Pain, Pulmonary Function Tests
The Effect of Superficial Parasternal Intercostal Plane Block on Pulmonary Function Tests After Cardiac Surgery
In adult patients undergoing cardiac surgery, does adding an sPIP block to standard care compared to standard care alone result in a smaller decrease in PFTs?
- Trial name
- PIPACS (NCT05999721)
- Testing
- superficial parasternal intercostal plane block, Standard care
- Where
- 2 sites in Israel
- Volunteers
- 100 people
- Sponsor
- Shai Fein
Coronary Artery Disease, Obesity
Structured Physiotherapy Program in Obese and Non-obese Patients
A routine physiotherapy program has been shown to be effective in the prevention and treatment of cardiopulmonary diseases. It also significantly increases functional capacity following coronary artery bypass grafting.
- Trial name
- NCT05357937
- Testing
- standard physiotherapy program
- Where
- Saudi Arabia
- Volunteers
- 50 people
- Sponsor
- University of Jazan
Asthma, Obesity
Study of the Physiology of the Asthma of the Obese Subjects. Breathing Obesity Asthma Study (BOA)
Asthma is more frequent in obese women, but the mechanisms underlying the causes of this increased frequency are unknown and are different from usual asthma pathophysiology (associated with allergy).
- Trial name
- BOA (NCT00577733)
- Where
- France
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Functioning Pancreatic Neuroendocrine Tumor, Intermediate Grade Lung Neuroendocrine Neoplasm
Testing Cabozantinib in Patients With Advanced Pancreatic Neuroendocrine and Carcinoid Tumors
This phase III trial studies cabozantinib to see how well it works compared with placebo in treating patients with neuroendocrine or carcinoid tumors that may have spread from where it first started to nearby tissue, lymph nodes…
- Conditions
- Functioning Pancreatic Neuroendocrine Tumor, Intermediate Grade Lung Neuroendocrine Neoplasm, Locally Advanced Digestive System Neuroendocrine Neoplasm, Locally Advanced Digestive System Neuroendocrine Tumor G1
- Trial name
- NCT03375320
- Testing
- Biospecimen Collection, Cabozantinib S-malate, Computed Tomography
- Where
- 432 sites in United States
- Volunteers
- 298 people
- Sponsor
- National Cancer Institute (NCI)
Infant, Premature, Diseases, Infant, Newborn, Diseases
Pulmonary Function Using Non-invasive Forced Oscillometry
The purpose of this observational study is to measure pulmonary function in term and preterm infants with and without pulmonary disease including respiratory distress syndrome, bronchopulmonary dysplasia, transient tachypnea of…
- Conditions
- Infant, Premature, Diseases, Infant, Newborn, Diseases, Bronchopulmonary Dysplasia, Respiratory Distress Syndrome, Newborn
- Trial name
- PUFFOR (NCT03346343)
- Testing
- Non-invasive forced airway oscillometry
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Right Ventricular Dysfunction, Cardiopulmonary Diseases
Right Heart and Lung Blood Flow During Exercise (RIGHT-NET 2.0)
RIGHT-NET 2.0 is a multicenter observational study with a retrospective-prospective design that builds on the original RIGHT-NET study.
- Conditions
- Right Ventricular Dysfunction, Cardiopulmonary Diseases, Pulmonary Hypertension
- Trial name
- RIGHT-NET 2 (NCT07851610)
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- IRCCS SYNLAB SDN
Chronic Obstructive Pulmonary Disease (COPD)
Exploring the Diagnostic Performance of Dynamic Chest Radiology in Chronic Obstructive Pulmonary Disease
The prevalence of chronic obstructive pulmonary disease (COPD) is on the rise, leading to an increasing economic and social burden. Currently, the diagnosis and staging of COPD heavily rely on pulmonary function testing.
- Trial name
- NCT06653413
- Where
- China
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- Nanfang Hospital, Southern Medical University
Pulmonary Hypertension
Assessment of Cardiac Function Using Combined Cardiovascular Magnetic Resonance and Cardiopulmonary Exercise Testing (CMR-CPET)
What problems limit patients' response to exercise? Using exercise cardiac magnetic resonance imaging to assess the heart's response, with simultaneous measurement of respiratory oxygen and carbon dioxide levels to assess the…
- Trial name
- CMR-CPET (NCT04729777)
- Testing
- Combined Cardiovascular Magnetic Resonance and Cardiopulmonary Exercise Testing
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- Royal Free Hospital NHS Foundation Trust