Clinical trials: Lung Function Testing
Cystic Fibrosis, CFTR Gene Dysfunction
CFTR Related Pancreatitis Study
The main causes of acute recurrent pancreatitis (ARP) or chronic pancreatitis (CP) in children are defects in genes that have been associated to pancreatitis.
- Trial name
- NCT04274413
- Testing
- Beta Adrenergic Sweat Test
- Sponsor
- The Hospital for Sick Children
Hematopoietic Stem Cell Transplantation
Physical Inactivity in Candidates of HSCT
Decreased number of steps and poorer quality of life are prevalently observed among candidates of hematopoietic stem cell transplantation (HSCT).
- Trial name
- NCT03915210
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Gazi University
Pulmonary Function Tests
Iron Status and Lung Function in Pediatric Asthma
Iron has a variable role regarding asthma and respiratory function. In addition, iron deficiency may affect spirometry results in asthmatic children.
- Trial name
- NCT05277610
- Testing
- iron studies
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Ain Shams University
Pulmonary Fibrosis, COVID-19
Pulmonary Fibrosis After Severe COVID-19 Pneumonia
Patients discharged after hospitalization for COVID-19 pneumonia were retrospectively selected by radiologically established criteria that at admission presented at chest computed tomography (CT) (i) normal lung parenchyma <50%…
- Trial name
- SPIFFERO (NCT06423560)
- Testing
- Computed tomography
- Where
- Italy
- Volunteers
- 61 people
- Sponsor
- IRCCS San Raffaele
Asthma
Comparative Effects of Buteyko Versus Pilates Breathing Combined With McKenzie Neck Exercises on Lung Function and Chest Expansion in Asthmatic Patients With Forward Head Posture
Asthma is characterized by airway inflammation and hyperinflation that flattens the diaphragm and increases reliance on accessory neck muscles.
- Trial name
- NCT07289789
- Testing
- Pilates Breathing Combined with McKenzie Neck Exercises, McKenzie Neck Exercises with Buteyko Breathing
- Where
- Pakistan
- Volunteers
- 22 people
- Sponsor
- Foundation University Islamabad
Inadequate or Impaired Respiratory Function, Diabetes
Effects of Respiratory Muscle Training in Obese Women
The objective of this study will be to evaluate the effects of inspiratory muscle training (IMT) on the physical fitness of obese women It is believed that the application of these exercises helps in the improvement of…
- Conditions
- Inadequate or Impaired Respiratory Function, Diabetes, Hypertension
- Trial name
- NCT03767556
- Testing
- Inspiratory muscle training
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidade Metodista de Piracicaba
PAH, Pulmonary Hypertension
A Study Evaluating the Long-Term Efficacy and Safety of Ralinepag in Subjects With PAH Via an Open-Label Extension
Study ROR-PH-303, ADVANCE EXTENSION, is an open-label extension (OLE) study for participants with WHO Group 1 PAH who have participated in another Phase 2 or Phase 3 study of ralinepag.
- Conditions
- PAH, Pulmonary Hypertension, Pulmonary Arterial Hypertension, Hypertension
- Trial name
- NCT03683186
- Testing
- Ralinepag
- Where
- 190 sites in United States, Argentina and 31 more
- Volunteers
- 1,000 people
- Sponsor
- United Therapeutics
Evaluations, Rehabilitation
3 Minutes Chair Rise Test (3CRT) in Patients With COPD
Improvement in the functional functioning and dyspnea of COPD patients after a rehabilitation program (RHB) is assessed by exercise tests and questionnaires difficult to replicate outside specialized centers.
- Conditions
- Evaluations, Rehabilitation, COPD
- Trial name
- 3CRT (NCT03286660)
- Testing
- Chair Rise Tests and short questionnaire
- Where
- 2 sites in France
- Volunteers
- 127 people
- Sponsor
- University Hospital, Lille
Inhalation Injury, Pulmonary Disease
The Effect of a Pulmonary Rehabilitation on Lung Function and Exercise Capacity in Patients With Burn
Inhalation burn injury and lung complications caused by large surface burns occurring during a fire remains a serious problem. Pulmonary rehabilitation has been used successfully to improve pulmonary function(PF) in patients with…
- Trial name
- NCT04125108
- Testing
- pulmonary rehabilitation
- Where
- South Korea
- Volunteers
- 120 people
- Sponsor
- Hangang Sacred Heart Hospital
Respiratory Tract Disease, Kidney Transplantation
Evaluation of the Respiratory Function in Renal Transplanted Children
Objectives: While a respiratory abnormality was found in 50% of pediatric renal transplant recipients in a study conducted in Belgium and the Netherlands in 2008, the respiratory status of transplanted children in France remains…
- Conditions
- Respiratory Tract Disease, Kidney Transplantation, Pediatric
- Trial name
- SPIROKID (NCT03571542)
- Testing
- pulmonary function
- Where
- 5 sites in France
- Volunteers
- 385 people
- Sponsor
- Nantes University Hospital
Bronchiectasis
Exercise Capacity in Bronchiectasis Resection
Bronchiectasis can be defined as an abnormal and irreversible dilatation of the bronchial tree due to repeated cycles of inflammation and infection, resulting in progressive loss of lung function.
- Trial name
- NCT01268475
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- University of Sao Paulo
Asthma
Study to Assess the Effect of the NEXThaler® Device (DPI - Dry Powder Inhaler) on the Central and Peripheral Airway Dimensions in Asthmatic Patients
The objective of this study is to evaluate the effect of the combination of formoterol and beclometasone dipropionate in a dry powder inhaler (NEXThaler®) on central and peripheral airway dimensions in asthmatic patients.
- Trial name
- NCT01650441
- Testing
- Beclomethasone dipropionate 100 µg + formoterol fumarate 6 µg, CT thorax
- Where
- Belgium
- Volunteers
- 31 people
- Sponsor
- University Hospital, Antwerp
Cystic Fibrosis (CF)
Machine Learning Prediction of Pulmonary Function in Children With Cystic Fibrosis
Cystic fibrosis is a multisystem genetic disorder characterized by progressive pulmonary impairment and extrapulmonary limitations.
- Trial name
- NCT07770854
- Testing
- Archived Multidimensional Clinical and Functional Assessment Data
- Where
- Turkey (Türkiye)
- Volunteers
- 31 people
- Sponsor
- Gazi University
Lung Function Tests, Markers of Inflammation
Health Effects Following Use of Lead Free Ammunition Used With HK416
The purpose of this study is to determine whether use of lead free ammunitions cause more respiratory problems than use of lead containing ammunitions.
- Trial name
- NCT01477645
- Where
- Norway
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Electric Impedance, Respiratory Function Tests
Prediction of COPD Severity Using Electrical Impedance Tomography
The purpose of this study is to predict the CT visual score of emphysema with EIT-based parameters, in order to provide a non-invasive and convenient method for the evaluation of lung structure and physiological and pathological…
- Conditions
- Electric Impedance, Respiratory Function Tests, Pulmonary Disease, Chronic Obstructive
- Trial name
- NCT06359145
- Where
- China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Chinese PLA General Hospital
Long Covid
Effects of a Physical Rehabilitation Program on Long COVID
The objective of this clinical trial is to analyze the clinical, functional, and laboratory effects of a rehabilitation protocol designed for patients with long COVID; it may include any of the following: sex/gender, age groups…
- Trial name
- ReabCovid (NCT07651371)
- Testing
- Physical rehabilitation, Treadmill ergometer, Pulley
- Where
- Brazil
- Volunteers
- 74 people
- Sponsor
- Universidade do Estado do Pará
Emphysema
Single-Breath Measurement Underestimates Ventilatory Volume According to Emphysema Severity
Although single breath helium (He) dilution measurement (VASB) is currently used in pulmonary function laboratories to assess functional alveolar volume and diffusing capacity for carbon monoxide, the extent to which VASB…
- Trial name
- NCT00528944
- Where
- United States
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Columbia University
Lung Diseases
Assessment of Exposures of the Mother-infant Pair to the Air Pollution of São Paulo
A single group of pregnant women who was analyzed in the first and in the third trimesters of pregnancy
- Trial name
- NCT02807038
- Testing
- Lung function test
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Diffuse Parenchymal Lung Disease
The Clinical Value of Serum KL-6 Changes on Evaluating Disease Development in Different Diffuse Parenchymal Lung Disease
Diffuse Parenchymal Lung Disease(DPLD) is a chronic progressive fibrosis lung disease that with a highly variable clinical process.Krebs von den Lungen-6 (KL-6) is a high-molecular-weight glycoprotein, classified as human MUC1…
- Trial name
- NCT03101397
- Where
- China
- Volunteers
- 180 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Tobacco Smoking, Respiratory Function
Yoga-Based Breathing Exercises in a Salt-Cave Environment Versus a Standard Clinical Setting in Smokers
This randomized controlled trial evaluated whether performing the same yoga-based breathing exercise program in a salt-cave environment produced different respiratory, functional, physical activity, and quality-of-life outcomes…
- Trial name
- SPELEO-SMOKERS (NCT07737587)
- Testing
- Yoga-Based Breathing Exercise Program in a Salt-Cave Environment, Yoga-Based Breathing Exercise Program in a Standard Clinical Setting
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sinop University