Clinical trials: Lung Nodule
Pulmonary Nodules, Lung Neoplasms
Deep Learning Time-Series Prediction of Long-Term Growth Patterns of Pulmonary Ground-Glass Nodules Using Serial CT
Pulmonary ground-glass nodules (GGNs) are commonly found on chest CT scans. Some stay stable for years, while others slowly or rapidly turn into lung cancer.
- Conditions
- Pulmonary Nodules, Lung Neoplasms, Adenocarcinoma of Lung
- Trial name
- GGN-Trajectory (NCT07647692)
- Testing
- Serial Thin-Slice Chest CT
- Where
- China
- Volunteers
- 4,750 people
- Sponsor
- Peking University People's Hospital
Pulmonary Nodule, Multiple
Ultra-Low Dose CT Denoising for Lung Nodule Detection
We will perform an ultra low-dose CT (ULDCT) in addition to a regular chest CT scan for adult patients undergoing a clinically indicated chest CT.
- Trial name
- NCT03159377
- Testing
- Ultra low dose chest CT
- Where
- Israel
- Volunteers
- 52 people
- Sponsor
- Sheba Medical Center
Lung Cancer
Percutaneous Image Guided Video-Assisted Thoracic Surgery (VATS) Resection of Lung Lesions
This is a phase II protocol to determine the safety and feasibility of Intraoperative CT fluoroscopy guidance for lung resection for small nodules.
- Trial name
- NCT01847209
- Testing
- Video-Assisted Thoracic Surgery (VATS) wedge resection
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Brigham and Women's Hospital
Lung; Nodule, Liver Metastases
Study of Different Gating Techniques for PET Image of Lung and Liver Lesions
Lesions blurred by respiratory motion are common in fluorine-18 PET/CT studies. To avoid these artefacts, several standard gating correction technics are available.
- Trial name
- PETGATQUANT (NCT05779865)
- Where
- Monaco
- Volunteers
- 29 people
- Sponsor
- Centre Hospitalier Princesse Grace
Pulmonary Nodule, Solitary, Pulmonary Nodule, Multiple
Dynamic Evolution of Pulmonary Nodules and Influence Factors of Its Clinical Decision-making
The researchers are aimed to investigate the dynamic evolution of indeterminate pulmonary nodules by a long-term follow-up of patients with different characteristics.
- Trial name
- DEPICT (NCT04857333)
- Testing
- CT scan, Antibiotics, Surgical Resection
- Where
- China
- Volunteers
- 1,800 people, healthy volunteers welcome
- Sponsor
- GuiBin Qiao
Lung Cancer, Peripheral Pulmonary Nodules
Research on New Diagnosis and Treatment Technologies for Early Lung Cancer
To verify the clinical effectiveness and safety of the airway tree navigation system constructed by artificial intelligence (AI) in the navigation diagnosis of peripheral pulmonary nodules (PPLs).
- Trial name
- NCT07000721
- Testing
- Preoperative navigation path planning using the SARS-pro navigation system, Preoperative navigation path planning using the VBN navigation system
- Where
- China
- Volunteers
- 92 people
- Sponsor
- Jisong Zhang
Solitary Pulmonary Nodule, Lung Neoplasms
Radiomics for Distinguishing Benign and Malignant Lung Nodules
Differentiating between benign (non-cancerous) and malignant (cancerous) pulmonary nodules is a critical step in determining appropriate patient management and cancer treatment planning.
- Conditions
- Solitary Pulmonary Nodule, Lung Neoplasms, Multiple Pulmonary Nodules
- Trial name
- NCT07852000
- Volunteers
- 255 people
- Sponsor
- Assiut University
Solitary Pulmonary Nodule, Biopsy, Fine-Needle
iNod System Human Feasibility Assessment
The purpose of this study is to demonstrate feasibility to access, visualize, and obtain specimens adequate for cytology of lung lesions in subjects with suspected lung cancer when using the iNod System.
- Trial name
- iNod (NCT02832284)
- Testing
- iNod System
- Where
- 3 sites in United States
- Volunteers
- 23 people
- Sponsor
- Boston Scientific Corporation
Lung Cancer, Lung Non-Small Cell Carcinoma
From Benchmark to Surgical Activity: the Role of Endobronchial Fiducial Markers for Ground Glass Lung Nodules Resection.
With the risen popularity of low-dose computed tomography (LDCT) for lung cancer screening, many patients present with peripheral pulmonary ground-glass nodules (GGNs) with a suspicious solid part.
- Conditions
- Lung Cancer, Lung Non-Small Cell Carcinoma, Lung; Node
- Trial name
- Vortex_US (NCT05801406)
- Testing
- Tornado (Cook)
- Where
- Italy
- Volunteers
- 5 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Lung Cancer
Evaluation of Computer-Aided Lung Nodule Detection Software in Thoracic CT for Riverain Technologies LLC
STUDY DESIGN: This is a retrospective, multi-reader, multi-case, (MRMC) randomized reader study. OBJECTIVE: Primary: The primary objective of this clinical study is to prove that a user aided with ClearRead CT InSight (CRCTI) is…
- Trial name
- NCT02440139
- Testing
- ClearRead CT Insight
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Virginia Polytechnic Institute and State University
Cryptococcosis, Lung Adenocarcinoma
Derivation and Validation of a Scoring System to Distinguish Cryptococcosis and Adenocarcinoma in Pulmonary Nodules
Pulmonary cryptococcosis often manifests as isolated or multiple nodules, easily mimicking lung cancer clinically and radiologically, which ascribes the poor sensitivity of Cryptococcus culture and rarely positive of Cryptococcal…
- Trial name
- NCT04554875
- Testing
- A scoring system
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Shanghai Pulmonary Hospital, Shanghai, China
Peripheral Pulmonary Lesion, Lung Nodule, Solitary
Robotic Versus Electromagnetic Bronchoscopy for Pulmonary LesIon AssessmeNT Using Integrated Intraprocedural Imaging
RELIANT 2 is a pragmatic randomized controlled trial. The goal of this study is to compare the diagnostic yield of robotic assisted bronchoscopy with integrated cone beam computed tomography to that of electromagnetic navigation…
- Trial name
- RELIANT 2 (NCT06654271)
- Testing
- Robotic assisted bronchoscopy (RAB), Electromagnetic navigation bronchoscopy (ENB)
- Where
- 4 sites in United States
- Volunteers
- 440 people
- Sponsor
- Vanderbilt University Medical Center
Pulmonary Nodules
Effects of Ba Duan Jin for Patients With Pulmonary Nodules
Many researches shows that Ba Duan Jin has clinical efficacy on cancer rehabilitation, respiratory diseases, psychological health, quality of life and so on.
- Trial name
- NCT03420885
- Testing
- Ba Duan Jin, Health Education
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Shanghai University of Traditional Chinese Medicine
COPD, Lung Cancers
Assessment the Effectiveness of BTVA in COPD and Ablation in Pulmonary Nodules by Pulmonary MRI
A Clinical Study Based on Magnetic Resonance Imaging of the Lungs to Assess the Efficacy of Thermal Vapor Ablation and Pulmonary Nodule Ablation in Chronic Obstructive Pulmonary Disease After Surgery.
- Trial name
- NCT07045532
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Shanghai Chest Hospital
Lung Cancer, Pulmonary Nodule, Solitary
Prospective Post-market Data Collection for Ion Endoluminal System to Understand CT to Body Divergence
The goal of this study is to collect post-market data for the Ion Endoluminal System to understand CT to body divergence.
- Trial name
- NCT04735341
- Testing
- Ion Endoluminal System
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Intuitive Surgical
Lung Cancer
Localization for Deep Lung Nodules: Microcoil Versus Contrast Injection
In recent years, the development of low-dose pulmonary computed tomography screening has led to the discovery of many small pulmonary nodules in the early stages.
- Trial name
- NCT03617029
- Testing
- Microcoil, Lipiodol
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- National Taiwan University Hospital Hsin-Chu Branch
Pulmonary Nodules
18G Ultrafine Cryoablation Needle for Coaxial Biopsy and Cryoablation of Pulmonary Nodules
This prospective, single-center clinical study will evaluate whether an 18-gauge ultrafine cryoablation needle can be used feasibly and safely during CT-guided coaxial transthoracic biopsy of pulmonary nodules.
- Trial name
- NCT07806981
- Testing
- 18G Ultrafine Cryoablation Needle
- Volunteers
- 30 people
- Sponsor
- Shanghai Chest Hospital
Lung Neoplasms, Lung Cancer
OTL38 Injection for Intraoperative Imaging of Folate Receptor Positive Lung Nodules
This is a phase 2, multi-center, single dose, open-label, exploratory study in suspected lung cancer patients scheduled to undergo endoscopic or thoracic surgery per CT/positron emission tomography imaging based on standard of…
- Trial name
- NCT02872701
- Testing
- OTL38 for Injection, Near infrared camera imaging system, Endoscopic or Thoracic Surgery
- Where
- 6 sites in United States, Netherlands
- Volunteers
- 100 people
- Sponsor
- On Target Laboratories, LLC
Pulmonary Nodules
The SEQUENCE Trial
This study will randomize participants undergoing a bronchoscopic biopsy of a peripheral pulmonary nodule for their standard of care to receive robotic-assisted bronchoscopy (RaB) and then staging linear endobronchial ultrasounnd…
- Trial name
- SEQUENCE (NCT06676956)
- Testing
- Linear EBUS first, Robotic-assisted bronchoscopy first
- Where
- 5 sites in United States
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Pulmonary Nodule, Multiple, Pulmonary Nodule, Solitary
Comparative Study on the Efficacy and Safety of Microwave Ablation and Lobectomy in the Treatment of Ground Glass Nodules Located in the Pulmonary Hilar Region
GGO is a characteristic focus of early lung cancer. Due to the abundant peripheral blood vessels and bronchial tissues around the GGO lesions located in pulmonary hilar, only lobectomy could be used for the surgical treat of…
- Trial name
- NCT05477251
- Testing
- microwave ablation, lobectomy
- Volunteers
- 100 people
- Sponsor
- RenJi Hospital