Clinical trials: Lung Transplantation
Chronic Graft-versus-host Disease
Tear Cytokine Analysis as a Prediction or Diagnostic Marker in Ocular GvHD
Investigate the profiles of tear cytokines in patients who underwent stem cell transplantation (SCT) and attempted to determine the applicability of tear cytokines in the diagnosis of chronic graft-versus-host disease (GVHD).
- Trial name
- NCT02411474
- Where
- South Korea
- Volunteers
- 21 people
- Sponsor
- Yonsei University
Transplant; Failure, Kidney, Renal Disease, End Stage
Oral Paricalcitol in Kidney Transplant Recipients
This study is being done to find out whether patients who receive a kidney transplant can benefit from taking the medication paricalcitol (trade name Zemplar®) as compared to kidney transplant recipients not taking this…
- Conditions
- Transplant; Failure, Kidney, Renal Disease, End Stage, Hyperparathyroidism, Secondary
- Trial name
- NCT00587158
- Testing
- Paricalcitol, Corticosteroid Avoidance Immune Suppression Protocol
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- Mayo Clinic
Physiological Effects of Drugs
Memantine for Corticosteroid-Induced Mood and Declarative Memory Changes
The purpose of this research is to determine if patients on corticosteroids who are given memantine will show improvement in memory compared to those receiving placebo (an inactive substance).
- Trial name
- NCT00280774
- Testing
- Memantine
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Texas Southwestern Medical Center
Lung Transplant
Impact of Cold Ischemia on Pulmonary Endothelial Dysfunction in Ex-vivo Pulmonary Reconditioning
The study population will be patients with planned double-lung transplant, with preoperative ex-vivo reconditioning procedure. The ex-vivo procedure will be performed for lungs considered as limit to be directly implanted…
- Trial name
- Endoth-Exvivo (NCT03987113)
- Testing
- Plasma concentration analysis during and after ex-vivo pulmonary reconditioning
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Hopital Foch
To Compare Lung Transplant Outcomes Between Study Patients and Standard Patients Who Have Already Undergone Lung Transplantation by Conventional Procedures, Lung Transplant
Planned Semi-Elective Lung Tx Study
When suitable donor lungs become available for a consented recipient, and the donor cross clamp time occurs between 6pm and 4am, the transplant procedure (anesthesia starting time) will be allowed to be moved to a 6am start or…
- Trial name
- NCT04601818
- Testing
- Experimental: Preserving of Donor Lungs
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- University of Florida
Covid19
The Impact of Fecal Microbiota Transplantation as an Immunomodulation on the Risk Reduction of COVID-19 Disease Progression With Escalating Cytokine Storm and Inflammatory Parameters
The gut microbiota provides an intestinal biological barrier against pathogens and has a pivotal role in the maintenance of intestinal homeostasis and modulation of the host immune system.
- Trial name
- FeMToCOVID (NCT04824222)
- Testing
- Human fecal microbiota, MBiotix HBI, SOC
- Volunteers
- 366 people
- Sponsor
- Medical University of Warsaw
Lung Transplant Failure
Respiratory Physiotherapy as a Tool to Increase the Number of Solid Organ Donors
The main objective of the project is to determine the variation of PaO2 / FiO2 (PaFi) after the use of mechanical insufflation-exsufflation (MI-E) or mechanical cough assistant in the donor in brain death (DBD) and in the…
- Trial name
- NCT06202859
- Testing
- MIE
- Where
- Spain
- Volunteers
- 160 people
- Sponsor
- Vall d'Hebron Institute Research
Solid Organ Transplant Rejection, COVID-19
AlloSure Guided Immuno-Optimization for COVID-19: An Early Experience
The utilization of AlloSure to help guide immunosuppression management in solid organ transplant recipients diagnosed with COVID-19
- Trial name
- Al-COVE (NCT04341103)
- Volunteers
- 500 people
- Sponsor
- CareDx