Clinical trials: Lutein
Retinitis Pigmentosa
Effects of Lutein in Retinitis Pigmentosa
Phase I/II double-masked, randomized, placebo-controlled, cross-over trial to determine effects of lutein on vision in retinitis pigmentosa, including safety and effective dosage assessment
- Trial name
- NCT00029289
- Testing
- Lutein (10 or 30 mg/day) capsules
- Where
- United States
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Intermediate Age-Related Macular Degeneration With Reticular Pseudodrusen
Lutein Iontophoresis in Intermediate AMD and Reticular Pseudodrusen - a Retrospective Study
There is limited data available on the efficacy and safety of Transscleral Lutein Iontophoresis (TSLI) in patients with in-termediate age-related macular degeneration (iAMD) and reticular pseudodrusen (RPD).
- Trial name
- NCT07420361
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Mario Damiano Toro
Exudative Age-related Macular Degeneration
Macular Pigment Density Evolution in Unilateral Wet AMD Versus Non AMD Patients With or Without Lutein and Zeaxanthine Supplementation
•Purpose: Age-related Macular Degeneration ( AMD) is the leading cause of blindness and visual impairment in industrialized countries.
- Trial name
- NCT01404845
- Testing
- Nutrof Total, food supplement without Lutein and Zeaxanthin
- Where
- 2 sites in France
- Volunteers
- 200 people
- Sponsor
- Affordance
Dry Eye Syndrome (DES)
Dietary Supplementation on Tear Secretion and Inflammation in DES
The goal of this clinical trial is to explore the effect of supplementation of fish oil, lutein and zeaxanthin on the symptoms of dry eye syndrome, antioxidant capacity, oxidative stress and anti-inflammatory capacity in DES…
- Trial name
- DES (NCT06738446)
- Testing
- Multicomponent dietary supplement group
- Where
- Taiwan
- Volunteers
- 52 people
- Sponsor
- Shih Chien Huang
Healthy Nutrition
DHA & Lutein and fMRI Brain Mapping in Healthy Children
Studies suggest that lutein and n-3 fatty acids may influence the development of a child's brain and may be related to how well children learn.
- Trial name
- NCT01789866
- Where
- Canada
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Stage 3 AMD
Lutein by Scleral Iontophoresis in AMD
The objective of the clinical investigation is to evaluate the performance, safety and degree of tolerability resulting from the use of the iontophoresis medical device in adult subjects diagnosed with AMD stage 3 (AREDS…
- Trial name
- NCT06925893
- Where
- Italy
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Federico II University
Macular Pigment Optical Density
"Visiobiane Anti-age" Effects on Vision Parameters
The purpose of this study is to determine the benefits of "Visiobiane Anti-age" dietary supplement on macular pigment optical density, contrast sensibility and visual acuity.
- Trial name
- NCT00449917
- Testing
- lutein, DHA, vitamins
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- PiLeJe
Carotid Atherosclerosis, Carotid Intimal Medial Thickness 1
Effects of Lutein Supplementation on Subclinical Atherosclerosis
This study is to investigate the possible positive effects of lutein and lycopene supplementation on early atherosclerosis in Beijing.
- Trial name
- NCT01534533
- Testing
- Lutein group, Combination group, Normal lutein control group
- Where
- China
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- Peking University
Age Related Macular Degeneration
Association of MPOD Values With Blue Light.
This study aims to investigate in healthy adults 18-65 years of age the association of electronic device blue light exposure and macular pigment optical density (MPOD) considering usual dietary intake of lutein and zeaxanthin…
- Trial name
- AMPBL19 (NCT04779398)
- Where
- Australia
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- The University of Queensland
Epiretinal Membrane, Macular Hole
Association of Lutein, Zeaxanthin and Brilliant Blue in Chromovitrectomy
The aim of this study is to test the efficacy of the combination of dye Lutein, Zeaxanthin and brilliant blue to stain the internal limiting membrane as well as the epiretinal membranes during the Vitrectomy surgery.
- Conditions
- Epiretinal Membrane, Macular Hole, Proliferative Diabetic Retinopathy
- Trial name
- NCT01627977
- Testing
- Dye of Lutein, Zeaxanthin and Brilliant Blue
- Where
- Brazil
- Volunteers
- 18 people
- Sponsor
- Federal University of São Paulo
Healthy Subjects
Lutein Absorption in Healthy Adults
This study will evaluate the absorption of lutein when consumed in different oil blends.
- Trial name
- NCT01730898
- Testing
- Study product containing lutein
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Abbott Nutrition
Macular Pigment Optical Density
Wenzhou Dry Age-related Macular Degeneration (AMD) Progression Study
To evaluate the correlation between macular pigment optical density (MPOD) levels and risk of progression in patients with age-related macular degeneration
- Trial name
- NCT03433885
- Where
- China
- Volunteers
- 300 people
- Sponsor
- The Eye Hospital of Wenzhou Medical University
Carotenoids
Yellow Potatoes and Carotenoids
This study will assess the effects of daily intake of yellow and white potatoes on plasma lutein and zeaxanthin concentrations. Skin carotenoid levels will be assessed using the Veggie Meter.
- Trial name
- NCT07606001
- Testing
- Yellow-flesh potatoes, White-flesh potatoes
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Florida
Cognitive Function
Influence of Eggs on Cognitive Performance
This clinical trial aims to evaluate the nutrients in eggs in healthy adult's cognitive performance. The main questions it aims to answer are: How do the nutrients in eggs impact visual cognitive performance (VCP) in generally…
- Trial name
- NCT06465888
- Testing
- egg whites, whole eggs, Omega-3 eggs
- Where
- United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
Alzheimer's Disease
Lutein and Alzheimer's Disease Study
Oxidative damage by free radicals may be involved in causing Alzheimer's disease (AD). Free radicals may lead to death of nerve cells and decline in brain function.
- Trial name
- LAD (NCT00596024)
- Testing
- lutein/zeaxanthin
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Oregon Health and Science University
Glaucoma, Open-Angle
European Nutrition in Glaucoma Management Trial
European Nutrition in Glaucoma Management (ENIGMA) trial will evaluate the effect of 18-month supplementation with lutein, zeaxanthin and meso-zeaxanthin on macular pigment (MP) levels, vision, cognition and serum biomarkers of…
- Trial name
- ENIGMA (NCT04460365)
- Testing
- 10 mg Lutein, 2 mg zeaxanthin, 10 mg meso-zeaxanthin
- Where
- Ireland
- Volunteers
- 64 people
- Sponsor
- Centre for Eye Research Ireland
DML Stage 3
LUTEIN BY SCLERAL IONTOPHORESIS IN PATIENTS WITH STAGE 3 AGE-RELATED MACULAR DEGENERATION (AMD)
The objective of the clinical investigation is to evaluate the performance, safety and degree of tolerability resulting from the use of the iontophoresis medical device in adult subjects diagnosed with AMD stage 3 (AREDS…
- Trial name
- NCT06465342
- Volunteers
- 80 people
- Sponsor
- OFFHEALTH S.p.A.
n-3 Polyunsaturated Fatty Acids, Selenium
Enriched QUARTET® Hen Eggs and Cardiovascular Function
Role of oxidative stress in the development of cardiovascular diseases is well known and extensively investigated, because of its direct effects on vascular function, but also on the activation of the immune response.
- Conditions
- n-3 Polyunsaturated Fatty Acids, Selenium, Vitamin E, Lutein
- Trial name
- NCT04564690
- Testing
- QUARTET® hen eggs (enriched in n-3 PUFA, selenium, vitamin E and lutein), Regular hen eggs
- Where
- Croatia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Josip Juraj Strossmayer University of Osijek
Minimal Erythema Dose, Skin Viscoelasticity
The Effect of 12-Week Dietary Intake of Lutein on Minimal Erythema Dose and Other Skin Parameters
The double-center, randomized, placebo-controlled, one-period effectiveness study will include 30 subjects (women, aged between 25 to 55 years, Fitzpatrick phototype II and III).
- Conditions
- Minimal Erythema Dose, Skin Viscoelasticity, Dermis Density
- Trial name
- VIST Lutein (NCT03811977)
- Testing
- Lutein syrup
- Where
- Slovenia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- VIST - Faculty of Applied Sciences
Biological Availability of Vitamins and Micronutrients
Effect of Genetic Variants on Fat-soluble Vitamin Bioavailability
The aim was to identify minor genetic variations (single nucleotide polymorphisms) that explain the interindividual variability in bioavailability of fat soluble micronutrients (fat soluble vitamins and carotenoids).
- Trial name
- VITAGENES (NCT02100774)
- Where
- France
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement