Clinical trials: Lymph Node Dissection
Nasopharyngeal Carcinoma, Surgery
Surgery Alone Verus Sugery Combined with Dose-reduced Radiotherapy for Newly Diagnosed Stage I Nasopharyngeal Carcinoma
The goal of this clinical trial is to compare the efficacy and safety of endoscopic nasopharyngectomy combined with retropharyngeal lymph nodes dissection plus bilateral upper neck lymph node dissection or plus postoperative…
- Conditions
- Nasopharyngeal Carcinoma, Surgery, Radiotherapy
- Trial name
- NCT06688760
- Testing
- Endoscopic nasopharyngectomy combine Retropharyngeal lymphadenectomy and Low Dose Radiotherapy, Endoscopic nasopharyngectomy combine Retropharyngeal lymphadenectomy and Double upper neck lymph node dissection
- Where
- 2 sites in China
- Volunteers
- 86 people
- Sponsor
- Ming-Yuan Chen
Colorectal Cancer
Robotic vs Laparoscopic D3-D4 Lymphadenectomy for Colorectal Cancer
Approximately one third of patients with colorectal cancer are diagnosed as locally advanced stage with metastasis to N3 - N4 lymph nodes requiring a D3 - D4 lymphadenectomy.
- Trial name
- NCT05961423
- Testing
- Robotic surgery
- Where
- Taiwan
- Volunteers
- 286 people
- Sponsor
- National Taiwan University Hospital
Breast Neoplasms
Safety and Effectiveness of Robotic-Assisted Remote Surgery for Breast Tumors
This is a multicenter retrospective clinical study. The research aims to explore the safety and efficacy of robotic single-port thoracoscopic minimally invasive surgery for breast cancer patients.
- Trial name
- NCT07850323
- Testing
- Robotic-assisted axillary lymph node dissection
- Where
- China
- Volunteers
- 25 people
- Sponsor
- Guangzhou Women and Children's Medical Center
Endometrial Cancer
Endometrial Cancer International Database
This project aims to determining prognostic factors and individualizing management decision per patient characteristics and endometrial cancer features.
- Trial name
- ECID (NCT04787159)
- Volunteers
- 1,000 people
- Sponsor
- Assiut University
Cutaneous Melanoma, Stage III
The Multicentre Selective Lymphadenectomy Trial - 3
The goal of this clinical trial is to demonstrate that there is no difference (non-inferiorty) in the 2 year recurrence-free survival (RFS) between 2 different surgical approaches for clinical Stage III melanoma.
- Trial name
- MSLT-3 (NCT07049276)
- Testing
- Index lymph node resection, Therapeutic lymph node dissection
- Where
- 8 sites in United States, Australia and 4 more
- Volunteers
- 1,500 people
- Sponsor
- Melanoma Institute Australia
Breast Cancer
Sentinel Lymph Node Biopsy Using Peritumoral Injection With Blue Dye Confirmation
We continue to collect information in support of the hypothesis that the histology of the first draining lymph node (sentinel node) accurately predicts the histology of the rest of the axillary lymph nodes.
- Trial name
- NCT00575744
- Testing
- Sentinel Node Biopsy
- Where
- United States
- Volunteers
- 699 people
- Sponsor
- University of Arkansas
Breast Cancer, Sentinel Lymph Node
Axillary Management in Breast Cancer Patients With Needle Biopsy Proven Nodal Metastases After Neoadjuvant Chemotherapy
The aim of this study is to assess whether, omitting further axillary treatment (ALND and ART) for patients with early stage breast cancer and axillary nodal metastases on needle biopsy, who after NACT have no residual cancer in…
- Conditions
- Breast Cancer, Sentinel Lymph Node, Neoplasm, Breast
- Trial name
- ATNEC (NCT04109079)
- Testing
- Axillary lymph node dissection, Axillary radiotherapy, Breast or chest wall radiotherapy
- Where
- 98 sites in Ireland, United Kingdom
- Volunteers
- 1,900 people
- Sponsor
- University Hospitals of Derby and Burton NHS Foundation Trust
Prostate Cancer
Radiation Therapy After Prostatectomy in Treating Patients With Stage III Prostate Cancer
Randomized phase III trial to compare treatment with or without adjuvant radiation therapy in men with stage III prostate cancer who have had radical prostatectomy and lymphadenectomy recently.
- Trial name
- NCT00394511
- Testing
- low-LET photon therapy
- Volunteers
- 408 people
- Sponsor
- National Cancer Institute (NCI)
Melanoma
Complete Lymph Node Dissection vs Watchful Waiting in Patients With Malignant Melanoma (Thickness of 1,0mm+ and Evidence of Metastases in the Sentinel Node)
Sentinel lymph node biopsy (SLNB) is considered as standard diagnostic procedure in melanoma patients carrying a reasonable risk for metastases.
- Trial name
- DeCOG-SLT (NCT02434107)
- Testing
- Completion Lymphadenectomy, Clinical Monitoring (Palpation and node ultrasound)
- Where
- 41 sites in Germany
- Volunteers
- 483 people
- Sponsor
- University Hospital Tuebingen
Breast Cancer
Surgery to Remove Sentinel Lymph Nodes With or Without Removing Lymph Nodes in the Armpit in Treating Women With Breast Cancer
RATIONALE: Removing the sentinel lymph nodes and examining them under a microscope may help plan more effective surgery for breast cancer.
- Trial name
- NCT00003830
- Testing
- conventional surgery, Sentinel node resection followed by node examination
- Where
- 78 sites in United States, Canada and 1 more
- Volunteers
- 5,611 people
- Sponsor
- NSABP Foundation Inc
Oligometastatic Hormone-Sensitive Prostate Cancer, Prostate Adenocarcinoma
Prospective Study on the Role of Radical Prostatectomy in Oligo-metastatic Hormone-sensitive Prostate Cancer in Patients on Androgen Deprivation Therapy
MAZINGA is a prospective, single-group pilot study evaluating disease control after robot-assisted radical prostatectomy with extended pelvic lymph-node dissection in men with oligometastatic hormone-sensitive prostate…
- Trial name
- MAZINGA (NCT07766486)
- Testing
- Robot-Assisted Radical Prostatectomy With Extended Pelvic Lymph-Node Dissection
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Fondazione del Piemonte per l'Oncologia
Early Gastric Cancer, Indocyanine Green
Indocyanine Green Tracer Using in Laparoscopic Distal Gastrectomy for Early Gastric Cancer
This study aims to explore the value of indocyanine green (ICG) in laparoscopic distal gastrectomy with lymph node dissection for early gastric cancer.The patients with early gastric adenocarcinoma (cT1, N-/+, M0) will be studied.
- Conditions
- Early Gastric Cancer, Indocyanine Green, Lymph Node Dissection
- Trial name
- NCT04973475
- Testing
- Indocyanine Green
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Fujian Medical University
Non-Small Cell Lung Cancer, Lymph Node Metastasis
XR-Assisted PET/CT Navigation for Cervical Lymph Node Dissection in Lung Cancer
This single-arm, prospective feasibility study evaluates an Extended Reality (XR) headset-based preoperative surgical planning workflow that fuses 18F-FDG PET metabolic hotspots with CT anatomy on the OpVerse platform, in…
- Conditions
- Non-Small Cell Lung Cancer, Lymph Node Metastasis, Supraclavicular Lymph Node Metastasis
- Trial name
- XR-NeckLND (NCT07593872)
- Testing
- OpVerse XR Surgical Planning Platform with HoloLens HMD, Cervical / Supraclavicular Lymph Node Dissection
- Volunteers
- 10 people
- Sponsor
- National Taiwan University Hospital
Neck Lymph Node Dissection, Immune Defects
Aerobic Exercises Versus Laser Puncture on Immune Response Following Neck Lymph Node Dissection
Group (1): Twenty cases with decreased white blood cell counts after neck lymph nodes and deficient in blood immunological functions made up this group. They underwent aerobic exercise training on a cycle ergometer.
- Trial name
- NCT06762886
- Testing
- Cycle ergometer, Low-level laser therapy
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Cervical Cancer
Sentinel Concept in Early Stage Cervical Cancer
Aim of present study is to inspect, if the removal alone of sentinel lymph nodes in women with early Cervix Carcinoma lead to, at equal length, overall survival like entire systematic dissection of lymph node and at the same time…
- Trial name
- NCT01157962
- Testing
- Lymphadenectomy in cervical cancer
- Where
- Germany
- Volunteers
- 1,600 people
- Sponsor
- Charite University, Berlin, Germany
Prostate Cancer
SPECT-CT Guided Lymphatic Mapping and Sentinel Lymphadenectomy (LM/SL) in Prostate Cancer
Nodal staging is a key-step in pre-treatment assessment of prostate cancer. In patients with a low probability of nodal metastasis, bilateral pelvic lymphadenectomy is controversial.
- Trial name
- NCT00773318
- Testing
- SPECT/CT guided LM/SL
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Lymphadenectomy
Prophylactic Lymphovenous Bypass Procedure Following Inguinal Lymphadenectomy or Pelvic Lymphadenectomy: A Prospective Observational Study
To learn if LBP can help to prevent lymphedema when it is performed at the time of surgery rather than after a patient has already developed the disease.
- Trial name
- NCT05992909
- Testing
- Lymphovenous bypass procedure
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- M.D. Anderson Cancer Center
Gastric Cancer
Lymph Node 14v Dissection in Clinical Stage T3N+, T4N+ of Gastric Cancer
The purpose of this study is to compare the survival rate according to the presence or absence of 14v lymph node dissection.
- Trial name
- NCT03264807
- Testing
- D2 lymphadenectomy, D2 and #14v lymphadenectomy
- Where
- 12 sites in South Korea
- Volunteers
- 518 people
- Sponsor
- National Cancer Center, Korea
Non-Small Cell Lung Cancer
Station 4L Lymph Node Dissection Versus No Dissection in Clinical Stage I Solid Nodule-Type Invasive NSCLC
This multicenter, prospective, randomized clinical trial will enroll adults aged 18 to 75 years with resectable clinical stage I (T1-T2aN0M0) invasive non-small cell lung cancer presenting as a single solid nodule…
- Trial name
- NCT07801430
- Testing
- Station 4L Lymph Node Dissection
- Where
- China
- Volunteers
- 384 people
- Sponsor
- Fudan University
Prostate Cancer
Early Prostate Cancer Recurrence With PSMA PET Positive Unilateral Pelvic Lesion(s)
Significant advances in molecular nuclear medicine imaging in prostate cancer have been achieved in recent years. In particular, the introduction of prostate-specific membrane antigen (PSMA) -based tracers has significantly…
- Trial name
- ProsTone (NCT04271579)
- Testing
- Salvage Lymphnode dissection
- Where
- Germany
- Volunteers
- 397 people
- Sponsor
- Martini-Klinik am UKE GmbH