Clinical trials: Lymph Node Neoplasm
Rectal Cancer, Gastric Adenocarcinoma
Carnoy's Solution Versus Formalin in Rectal and Gastric Cancer Specimens Following: a Randomized Trial
This study evaluates the number of lymph nodes dissected in specimens following fixation with 10% neutral buffered formaldehyde or Carnoy's solution. Specimens were randomized for fixation in each solution.
- Trial name
- NCT02629315
- Testing
- Carnoy's solution, 10% neutral buffered formaldehyde
- Volunteers
- 130 people
- Sponsor
- Instituto do Cancer do Estado de São Paulo
Malignant Neoplasm of Breast
ICG Fluorescence Technique for the Detection of Sentinel Lymph Nodes
Objectives of Clinical Trial The main objective of this clinical trial is to show the efficacy of fluorescence lymphangiography with indocyanine green (ICG) for the detection of sentinel lymph nodes.
- Trial name
- NCT01395706
- Testing
- ICG Fluorescence technique
- Where
- Germany
- Volunteers
- 125 people
- Sponsor
- Pulsion Medical Systems SE
Colon Cancer
A Prospective Randomized Study Comparing Sentinel Lymph Node (SLN) Evaluation With Standard Pathological Evaluation for the Staging of Colon Carcinoma
The objective of this trial is to define the rate of upstaging of colon carcinoma lymph node metastasis with sentinel lymph node (SLN) mapping.
- Trial name
- NCT01623258
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Walter Reed Army Medical Center
Biliary Tract Cancer
A Phase II Trial of Preoperative Chemotherapy for Biliary Tract Cancer (BTC) With Node Metastasis
To evaluate the efficacy and the safety of preoperative chemotherapy with Gemcitabine/ Cisplatin /S-1 for biliary tract cancers with lymph node metastasis by FDG-PET.
- Trial name
- NCT01821248
- Testing
- Gemcitabine, Cisplatin, S-1
- Where
- Japan
- Volunteers
- 25 people
- Sponsor
- Kansai Hepatobiliary Oncology Group
Advanced Gastric Cancer
Clinical Study on the Harvesting Lymph Nodes With Carbon Nanoparticles for Advanced Gastric Cancer
Carbon Nanoparticles (CNP),with a mean size of 150 nm,can be taken up selectively by lymphatics after injection into the tissue and draining regional lymph nodes are thereby colored black,which may provide surgeons the guidance…
- Trial name
- NCT02123407
- Testing
- Carbon Nanoparticles, Gastrectomy with D2 dissection
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Peking University
Breast Cancer
Response-Based Local Therapy for Regionally Advanced Breast Cancer
The goal of this interventional clinical trial is to evaluate if an individualized treatment strategy (involving radiation boost, surgery, and systemic consolidation) can improve progression-free survival in patients with breast…
- Trial name
- NCT07376538
- Testing
- Response-adapted comprehensive treatment strategy
- Where
- China
- Volunteers
- 157 people
- Sponsor
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Laparoscopic Hysterectomy and Sentinel Lymph Node Biopsy
Complications of Laparoscopic Hysterectomy and Sentinel Lymph Node Biopsy for Endometrial Carcinoma
Endometrial adenocarcinoma is believed to be a more treatable malignancy. Poor prognosis is associated with age, grade and depth of myometrial invasion, lymph node status, tumor size, invasion of lymphovascular space and…
- Trial name
- NCT04894552
- Testing
- Laparoscopic Hysterectomy and Sentinel Lymph Node Biopsy for Endometrial Carcinoma
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Ain Shams Maternity Hospital
Prostate Cancer, Bladder Cancer
Study of Ferumoxytol Enhanced MRI for Detecting Lymph Node Metastases in Prostate, Bladder, and Kidney Cancers
Background: People with prostate, bladder, or kidney cancer often have their cancer spread (metastasize) to lymph nodes. It is important for your doctor to know if this has occurred but currently it can be hard to determine if…
- Conditions
- Prostate Cancer, Bladder Cancer, Kidney Cancer
- Trial name
- NCT02141490
- Testing
- Ferumoxytol, Magnetic Resonance Imaging (MRI)
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- National Cancer Institute (NCI)
Colon Neoplasms, Right Colon Tumors
Multicenter Prospective Study Protocol for Validating Surgical Quality Standards in D3 Lymphadenectomy for Oncological Right Hemicolectomy
Introduction: D3 lymphadenectomy (D3L) for right hemicolectomy, proposed by Eastern guidelines, aims to improve oncological outcomes by extending resection to include lymphatic drainage zones beyond those addressed by complete…
- Conditions
- Colon Neoplasms, Right Colon Tumors, Lymphadenectomy
- Trial name
- D3L (NCT07847216)
- Testing
- Right Colectomy & D3 Lymphadenectomy
- Volunteers
- 120 people
- Sponsor
- Fundació d'investigació Sanitària de les Illes Balears
Breast Cancer Related Lymphedema, Lymphedema Arm
The Effectiveness of Lymphatic Bypass Supermicrosurgery
This study evaluate the effectiveness of lymphatic bypass supermicrosurgery (LBS) and axillary lymph node dissection (ALND) compare to ALND alone to prevent breast cancer treatment-related lymphedema (BCRL).
- Trial name
- ELYBS (NCT05682885)
- Testing
- Lymphatic Bypass Supermicrosurgery
- Where
- Indonesia
- Volunteers
- 140 people
- Sponsor
- Dharmais National Cancer Center Hospital
Melanoma
Pilot Study of IFN α2b for Melanoma Patients
The presence of malignant cells in lymph nodes is a critical parameter in the staging of melanoma cancer patients. Assessment of lymph nodes is currently done by histopathology alone.
- Trial name
- NCT00871533
- Testing
- IFNα2b, PEG- IFNα2b
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Pittsburgh
Breast Cancer, Triple Negative Breast Cancer
Avoiding Sentinel Lymph Node Biopsy in Breast Cancer Patients After Neoadjuvant Chemotherapy
This study evaluates whether SLNB can safely be omitted in breast cancer patients with HER2+ or TN tumors who achieve a radiological complete response on MRI after neoadjuvant systemic therapy
- Conditions
- Breast Cancer, Triple Negative Breast Cancer, HER2-positive Breast Cancer, Sentinel Lymph Node
- Trial name
- ASICS (NCT04225858)
- Testing
- Omission of sentinel lymph node biopsy
- Volunteers
- 340 people
- Sponsor
- The Netherlands Cancer Institute
Papillary Thyroid Cancer, Lymph Node Metastasis
Frozen Section-Guided Selective Ipsilateral Central Neck Dissection in Bethesda V-VI Thyroid Nodules
The goal of this observational pilot cohort study is to evaluate the feasibility and clinical implications of frozen section analysis-guided selective ipsilateral central neck dissection in adult patients undergoing primary…
- Trial name
- NCT07659717
- Testing
- Frozen section analysis (FSA)
- Where
- Italy
- Volunteers
- 66 people
- Sponsor
- Eleonora Lori, MD
Thyroid Cancer, Thyroidectomy With Central Lymph Node Dissection
Does Parathyroid Autofluorescence Reduces Unintensional Parathyroidectomy During Total Thyroidectomy With Central Lymph Node Compartment Dissection
The aim of the study is to evaluate the effectiveness of autofluorescence in the intraoperative preservation of parathyroids during total thyroidectomy with central lymph node compartment dissection.
- Trial name
- FLUOBCC (NCT04339478)
- Where
- 2 sites in Greece, Jordan
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Rectal Cancer
Preoperative Assessment of Mesorectal Lymph Nodes by Dual Energy CT. PUMK-DECT
Endpoints subproject 1: To develop a reproducible method for the detection of lymph nodes by DECT in operation specimens from rectal resection for cancer.
- Trial name
- NCT02592304
- Testing
- Dual energy computed tomography
- Where
- Denmark
- Volunteers
- 70 people
- Sponsor
- Odense University Hospital
Lung Cancer
Endobronchial Ultrasound Elastography: the Utility of Strain Ratio for Lymph Node Staging in Lung Cancer Patients
The aim of this pilot study is to evaluate EBUS elastography strain ratio in assessment of mediastinal lymph nodes in patients with suspicion for lung cancer for the first time.
- Trial name
- NCT02009319
- Where
- Slovenia
- Volunteers
- 33 people
- Sponsor
- The University Clinic of Pulmonary and Allergic Diseases Golnik
Breast Cancer
Spot tm Tattooing of Biopsied Axillary Lymph Nodes With Ultrasound Guided in Breast Cancer Patients Prior to Surgery
To assess feasibility and clinical utility of marking biopsied axillary lymph nodes with Spot at time of biopsy.
- Trial name
- NCT02617264
- Testing
- SPOT
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Kaplan Medical Center
Breast Cancer
Surgical Resection With or Without Axillary Lymph Node Dissection in Treating Women With Node-Negative Breast Cancer and Sentinel Lymph Node Micrometastases
RATIONALE: Surgery to remove lymph nodes in the armpit in patients with sentinel lymph node micrometastases may remove cancer cells that have spread from tumors in the breast.
- Trial name
- 23-01 (NCT00072293)
- Testing
- Axillary lymph node dissection, No axillary lymph node dissection
- Where
- 31 sites in Australia, Belgium and 8 more
- Volunteers
- 931 people
- Sponsor
- ETOP IBCSG Partners Foundation
Breast Neoplasms
Frozen Section Examination of Sentinel Lymph Nodes in Breast Cancer
This prospective randomized clinical study evaluates the role of intraoperative frozen section examination of sentinel lymph nodes in patients with breast cancer.
- Trial name
- NCT07591506
- Testing
- Intraoperative Frozen Section Examination of Sentinel Lymph Node, Routine Postoperative Histopathological Evaluation of Sentinel Lymph Node
- Where
- Turkey (Türkiye)
- Volunteers
- 142 people
- Sponsor
- Izmir City Hospital
Thyroid Cancer
The Effect of the Number of Central Lymph Nodes on Changes in Parathyroid Function
This study collected data from patients who underwent thyroidectomy in the Breast and Thyroid Surgery Department of Shandong Provincial Hospital from January 2020 to December 2023 by reviewing medical records.
- Trial name
- NCT06432244
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Shandong Provincial Hospital
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