Clinical trials: Lymphatic Edema
Breast Cancer-related Subclinical Lymphedema
Subclinical Lymphedema Treatment Study
Primary Objective To compare the effectiveness of 2 treatment protocols for patients with breast cancer-related subclinical lymphedema identified through bioimpedance spectroscopy, L-dex scores Secondary Objectives To determine…
- Trial name
- SLT (NCT03292198)
- Testing
- 20-30 mmHg compression sleeve and gauntlet, Manual Lymphatic Drainage
- Where
- United States
- Volunteers
- 267 people
- Sponsor
- Mercy Research
Breast Cancer Lymphedema
Axillary Reverse Mapping (ARM) in Breast Cancer Surgery to Prevent Lymphedema. (ARMtrial)
Breast cancer related lymphedema (BCRL) is a debilitating and distressing condition affecting approximately one out of five breast cancer survivors.
- Trial name
- NCT03333226
- Testing
- Axillary Reverse Mapping (ARM)
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- University Hospital of Ferrara
Trachoma, Lymphatic Filariases
Cluster RCT of Co-administration Azithromycin, Albendazole & Ivermectin
Cluster-randomised trial comparing co-administration of Azithromycin/Ivermectin/Albendazole with separate administration of Azithromycin and Ivermectin/Albendazole.
- Trial name
- NCT03570814
- Testing
- Administration of Albendazole on Day 1, Administration of Ivermectin on Day 1, Administration of Azithromycin on Day 1
- Where
- Ethiopia
- Volunteers
- 13,511 people
- Sponsor
- London School of Hygiene and Tropical Medicine
Lymphoedema
Intermittent Pneumatic Compression for Treating Lower Limb Lymphoedema
The treatment of lymphoedema and its associated complications represent a considerable drain on increasingly limited NHS resources.
- Trial name
- IMPRESS (NCT03825263)
- Testing
- Intermittent Pressure Compression
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- University of South Wales
Lower Extremity Lymphedema
Daphnetin Capsules for Lower Limb Lymphoedema Following Gynaecological Surgery
This clinical trial is designed to learn more about treating patients with lower limb lymphoedema following gynaecological surgery.
- Trial name
- NCT06329167
- Testing
- Daphnetin, Aescuven
- Where
- China
- Volunteers
- 100 people
- Sponsor
- The First Hospital of Jilin University
Fetal Hydrops
Precision Medical Research of Non-immune Fetal Hydrops (NIFH)-From Prenatal Diagnosis to Intrauterine Treatment
Based on multi-center clinical research resources, a large-scale prospective cohort study will be conduted to make a more accurate diagnosis and intervention plan of Non-immune fetal hydrops (NIFH), and then establish NIFH…
- Trial name
- NCT02956564
- Testing
- intrauterine intervention
- Volunteers
- 144 people
- Sponsor
- Shanghai First Maternity and Infant Hospital
Lymphedema of Arm
Horse Chestnut Seed Extract for Lymphedema
To help Treat Lymphedema of the Arm in Breast Cancer Survivors with Horse chestnut Seed Extract
- Trial name
- NCT00213928
- Testing
- Horse Chestnut Seed Extract
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- University of Wisconsin, Madison
Lymphedema of Upper Arm, Breast Cancer
Noninvasive Assessment of Lymphedema Among Breast Cancer Survivors
This proof of concept study will evaluate the ability of a new, ultrasound based technology called Bullseye Constructive Shearwave Interference (CSI) (trade name, Bullseye Elasticity Quantification) to measure lymphedema of the…
- Trial name
- NCT05278871
- Testing
- Constructive Shearwave Interference (CSI)
- Where
- 2 sites in United States
- Volunteers
- 21 people
- Sponsor
- Microelastic Ultrasound Systems Inc
Breast Edema, Breast Cancer Related Lymphoedema
Effectiveness of Kinesio Taping in Patients With Chronic Breast and/or Truncal Oedema After Treatment for Breast Cancer.
The goal of the KiTaLymph trial is to investigate whether the application of kinesio tape is effective in women with persistent (>6 months) breast and/or truncal oedema after treatment for breast cancer.
- Conditions
- Breast Edema, Breast Cancer Related Lymphoedema, Breast Cancer Related Lymphedema, Truncal Lymphedema
- Trial name
- KiTaLymph (NCT07080476)
- Testing
- Decongestive lymphatic therapy, Kinesio tape, Compression bra (sub-study)
- Where
- 4 sites in Belgium
- Volunteers
- 128 people
- Sponsor
- Universiteit Antwerpen
Breast Cancer Lymphedema
Tacrolimus as Treatment of Breast Cancer-Related Lymphedema
BACKGROUND Breast cancer-related lymphedema is a severe and life-long side-effect to breast cancer treatment. The condition increases the risk of infections and decreases health-related quality of life (HR-QOL) in patients.
- Trial name
- NCT04541290
- Testing
- Protopic 0.1 % Topical Ointment
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- Odense University Hospital
Lymphedema, Breast Cancer
Gentle Touch for Post-Mastectomy Lymphedema
This is a single-blind, parallel-group Randomized Controlled Trial (RCT) comparing the efficacy of a specialized manual technique, Gentle Touch (GT), versus a control intervention, both added to the usual rehabilitative care.
- Trial name
- GT-BCRL (NCT07257679)
- Testing
- Gentle Touch (GT) Lymphatic Drainage (ANDOS technique), Passive Mobilization and Active-Assisted Exercises for the Upper Limb
- Where
- 2 sites in Italy
- Volunteers
- 36 people
- Sponsor
- I.R.C.C.S. Fondazione Santa Lucia
Breast Neoplasm, Lymphedema
Effectiveness of Fluoroscopy-guided MLD for Treatment of BCRL
The main scientific objective of this multicentric double-blinded randomised controlled trial entails examining the effectiveness of fluoroscopy-guided MLD versus traditional MLD versus placebo MLD, applied as part of the…
- Trial name
- EFforT-BCRL (NCT02609724)
- Testing
- Information, Skin care, Compression therapy
- Where
- 3 sites in Belgium
- Volunteers
- 194 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Lower Extremity Lymphedema
Non-inferiority of Compression Bandage Alone in Lower Extremity Lymphedema Management
Lymphedema is much more than a disease with edema. Impaired lymphatic drainage triggers adipose tissue deposition and fibrosis. Fibrosis causes lymphatic vessel dysfunction. Therefore, treatment of fibrosis is important.
- Trial name
- NCT06750679
- Testing
- Compression bandage, Manual lymphatic drainage added to compression
- Where
- Turkey (Türkiye)
- Volunteers
- 31 people
- Sponsor
- Abant Izzet Baysal University
Compression; Vein, Venous Insufficiency
Digital Supported Compression Bandaging in Patients With Chronic Edema in the Lower Limbs
Patients with chronic edema of the lower limb referred to compression bandaging in a hospital setting will be invited to participate in the validation study of a novel sensor (CIMON), which have been developed for assessing the…
- Conditions
- Compression; Vein, Venous Insufficiency, Lymphedema of Leg, Digital Technology
- Trial name
- CIMON (NCT06438133)
- Testing
- CIMON, Sens Motion
- Where
- 5 sites in Denmark
- Volunteers
- 52 people
- Sponsor
- Carsten Bogh Juhl
Lymphedema, Breast Neoplasm
Presentation of First Time Attenders at Lymphedema Clinics
The first aim of this research project is to identify what factors motivate patients to seek assessment for early lymphedema and further, to gain insight into the signs and symptoms of developing lymphedema and the concurrent…
- Trial name
- NCT03687749
- Where
- 2 sites in Australia, Belgium
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Lymphedema, Cancer
Complex Decongestive Physiotherapy Applied After Lymphovenous Anastomosis Surgery
Type of this study: Prospective randomized controlled study. The aim of our study is to compare patients with lymphedema who have undergone lymphovenous anastomosis surgery receiving Complex Decongestive Physiotherapy (CDP)…
- Trial name
- NCT06167993
- Testing
- Complex Decongestive Physiotherapy
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 26 people
- Sponsor
- Necmettin Erbakan University