Clinical trials: Lymphatic Function
Intermittent Fasting, Dyslipidemias
Intermittent Fasting in Dyslipidemia
World Health Organization report notifies of the escalating global burden of cardiovascular diseases (CVD), projecting that it will become the major worldwide cause of death and disability by 2020.
- Conditions
- Intermittent Fasting, Dyslipidemias, HDL Cholesterol, Low Serum, Hepatic Enzymes and Function Abnormalities
- Trial name
- NCT03805776
- Testing
- Fasting (diet restruction for specific period)
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Anemia
High Dose IV Iron Plus ESA in Chemotherapy-induced Anemia
This study is a multicenter, prospective, randomized phase 3 clinical study comparing the efficacy and safety of the combination treatment of ESA and high-dose IV iron (darbepoietin alfa + ferric derisomaltose/iron isomaltoside)…
- Trial name
- NCT05768997
- Testing
- Ferric Derisomaltose Injection, Darbepoetin Alfa Injection
- Where
- South Korea
- Volunteers
- 312 people
- Sponsor
- Hallym University Medical Center
Immune Thrombocytopenia
Association of Platelet Parameters With Bleeding Severity in Children With ITP
Patients with severe immune thrombocytopenia (ITP) present with similarly low platelet counts but varying bleeding symptoms, making it difficult to predict the disease course and to decide on an appropriate treatment plan.
- Trial name
- ITP-APPS (NCT03810352)
- Where
- 6 sites in United States
- Volunteers
- 95 people
- Sponsor
- Boston Children's Hospital
Anemia
Effect of Aerobic Training Supported by AI-Based Monitoring on Functional Performance in University Students With Anemia
This study aims to examine the impact of aerobic training supported by AI-based monitoring on functional performance in university students with anemia.
- Trial name
- NCT07882706
- Testing
- Aerobic Treadmill Training, AI-Supported Adaptive Cognitive Training, Standard Care for Anemia
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Hemophilia
Assessment of Proprioceptive and Functional Characteristics in Patients With Hemophilia
Analyze and evaluate the skeletal muscle of patients affected with hemophilia in the Region of Murcia. Describe the periarticular muscular deficit of the lower limbs, depending on the degree of injury: acute and chronic, or…
- Trial name
- HE-BALANCE (NCT02165592)
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universidad Católica San Antonio de Murcia
Obesity, Weight Loss
Evaluation of Bariatric Endoscopic Antral Myotomy (BEAM) as a Treatment for Obesity
In the proposed study, we will be evaluating the effects of pylorus sparing antral myotomy alone, without concomitant endoscopic sleeve gastroplasty (ESG), on weight loss for subjects undergoing the procedure with a history of…
- Conditions
- Obesity, Weight Loss, Delayed Gastric Emptying Following Procedure, Obesity, Mild
- Trial name
- BEAM (NCT05713071)
- Testing
- Bariatric Endoscopic Antral Myotomy
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Brigham and Women's Hospital
Sickle Cell Anemia, Muscle Dysfunction
Physical Rehabilitation in Sickle Cell Anemia
Sickle cell anemia (SCA) is one of the most neglected diseases worldwide, according to the World Health Organization. In the adult population with SCA, the systemic effects of the disease, such as respiratory and peripheral…
- Conditions
- Sickle Cell Anemia, Muscle Dysfunction, Quality of Life, Physical Activity
- Trial name
- NCT04705792
- Testing
- Physical activity
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- Centro Universitário Augusto Motta
Melanoma
Prospective Measurement of Post-Treatment Lymphedema
The goal of this study is to measure the amount of limb swelling (lymphedema) that sometimes occurs after melanoma treatment, and to find out how people feel and react to the diagnosis and treatment of melanoma.
- Trial name
- NCT00495950
- Testing
- Questionnaire
- Where
- United States
- Volunteers
- 350 people
- Sponsor
- M.D. Anderson Cancer Center
Hemophilic Arthropathy
The Effects of Exercises on Gait in Hemophilic Individuals
Arthropathy characterized by synovitis, cartilage degeneration, subchondral and interosseous cysts occur due to hemorrhage in hemophilia.
- Trial name
- NCT04297696
- Testing
- Therapeutic exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 19 people
- Sponsor
- Cukurova University
Acute Lymphoblastic Leukemia
Endothelial Function, Arterial Stiffness and Components
Specific Aim: Compare the endothelial function, arterial stiffness and components of metabolic syndrome of childhood Acute Lymphoblastic Leukemia (ALL) survivors to healthy sibling controls.
- Trial name
- NCT01439217
- Where
- 2 sites in United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Head and Neck Cancer
Effects of a Home-Based Exercise Program During Radiotherapy
The purpose of this study is to examine the effects of exercise on individuals with head and neck cancer who are receiving postoperative radiotherapy. The study is based on three primary hypotheses: 1.
- Trial name
- NCT07376213
- Testing
- Home-based exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Burak Ertürk
Iron Deficiency, Anemia
The Effects of Iron and Omega-3 Fatty Acid Supplementation on Cognition and Immune Function in Iron Deficient Children
The aim of this study is to determine if providing iron and a mixture of DHA and EPA, alone and in combination, to children with iron deficiency and poor n-3 fatty acid intake will improve their cognitive performance, activity…
- Trial name
- FeFA (NCT01092377)
- Testing
- DHA and EPA Fish Oil capsule, Iron tablet
- Where
- South Africa
- Volunteers
- 320 people
- Sponsor
- North-West University, South Africa
Hodgkin Lymphoma, Diffuse Large B Cell Lymphoma
To Decrease Fatigue With Light Therapy
Cancer related fatigue (CRF) is one of the most prevalent and distressing long-term complaints reported by (non-) Hodgkin survivors.
- Trial name
- SPARKLE (NCT03242902)
- Testing
- Light therapy intensity 1, Light therapy intensity 2
- Where
- 9 sites in Netherlands
- Volunteers
- 166 people
- Sponsor
- The Netherlands Cancer Institute
Sickle Cell Disease
Voxelotor Brain Oxygenation and Neurocognitive Study
This is an open label, single arm multicenter trial to evaluate the effect of voxelotor treatment on cerebral blood flow (CBF) and neurocognitive function in adolescent and young adult participants (12-30 years of age) with…
- Trial name
- NCT05228821
- Testing
- Voxelotor Oral Tablet
- Where
- 2 sites in United States
- Sponsor
- Pfizer
Lymphedema of Upper Limb
Evaluation of Respiratory Parameters in Patients With Upper Limb Lymphedema
The aim of our study is to assess disease severity, respiratory muscle strength, respiratory functions, pectoralis minor muscle shortening, functionality, and quality of life (QoL) in patients with upper limb lymphedema (ULL)…
- Trial name
- NCT06568978
- Testing
- Assessments of respiratory parameters
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Asthma; Eosinophilic
Evaluating the Effect of Benralizumab in Severe, Poorly-controlled Eosinophilic Asthma Using Inhaled Hyperpolarized 129-Xenon MRI
The purpose of this study is to evaluate the effect of a drug called benralizumab in individuals with severe, poorly controlled asthma with eosinophilic airway inflammation.
- Trial name
- AERFLO (NCT03733535)
- Testing
- Benralizumab, 129 Xenon
- Where
- Canada
- Volunteers
- 29 people
- Sponsor
- Dr. Grace Parraga
Sarcoidosis, Pulmonary Rehabilitation
Comparison of the Effects of Yoga and Conventional Physiotherapy Programs in Sarcoidosis
Sarcoidosis is a multisystem disease, characterized by the formation of immune granulomas with various clinical symptoms depending on the involved organs, which can involve many organs and systems associated with emotional and…
- Conditions
- Sarcoidosis, Pulmonary Rehabilitation, Yoga
- Trial name
- NCT06848608
- Testing
- traditional physiotherapy group, yoga program
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Saglik Bilimleri Universitesi
Epilepsy in Children, Coagulation and Hemorrhagic Disorders
The Prevalence and Risk Factors of Coagulopathy in Pediatric Epilepsy Surgery Patients
The hematologic consequences of novel Anti-seizure medications (ASMs) are rarely reported. Whether coagulation dysfunctions increase the risk of peri-operative bleeding remains controversial.
- Conditions
- Epilepsy in Children, Coagulation and Hemorrhagic Disorders, Epilepsy; Seizure, Antiepileptic Adverse Reaction
- Trial name
- NCT05675254
- Where
- China
- Volunteers
- 494 people
- Sponsor
- Children's Hospital of Fudan University
Obstructive Sleep Apnea (OSA), OSA
Automated Manual Lymphatic Drainage Therapy to Improve Glymphatic Function in OSA Patients
The purpose of this research is to investigate whether enhancing systemic lymphatic drainage improves glymphatic function in patients with obstructive sleep apnea (OSA).
- Conditions
- Obstructive Sleep Apnea (OSA), OSA, Obstructive Sleep Apnea
- Trial name
- NCT07301762
- Testing
- Automated manual lymphatic drainage therapy (AMLDT) device
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Mayo Clinic
Breast Cancer, Breast Cancer Lymphedema
The Recovery of Reaching Movement in Breast Cancer Survivors: Two Different Rehabilitative Protocols in Comparison
This study emphasizes the importance of rehabilitation in breast cancer survivors after mastectomy, even during the course of radiotherapy and chemotherapy, both for good efficacy in reducing pain and for functional recovery of…
- Conditions
- Breast Cancer, Breast Cancer Lymphedema, Pain, Pain, Postoperative
- Trial name
- NCT04166279
- Testing
- Single rehabilitative treatment, Group rehabilitative treatment
- Where
- Italy
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University of Roma La Sapienza