Clinical trials: Lymphedema, Secondary, open to volunteers
Lymphedema of Upper Limb
Novel MRI Techniques on Evaluation of Lymphedema
In this project, the investigators aim to investigate the imaging approaches for breast cancer-related secondary lymphedema. The clinical study aims to optimize the conventional MRI methods for mapping lymphedema and assess the…
- Trial name
- NCT05804643
- Testing
- Diffusion magnetic resonance imaging
- Where
- Taiwan
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Head and Neck Squamous Cell Carcinoma, Lymphedema, Secondary
Reconstruction of Cervical Lymphatic System During Head and Neck Squamous Cell Carcinoma Surgery
Head and neck squamous cell carcinoma is one of the most common malignant tumors. At present, the standard treatment of head and neck squamous cell carcinoma recommended by the National Comprehensive Cancer Network(NCCN)…
- Conditions
- Head and Neck Squamous Cell Carcinoma, Lymphedema, Secondary, Neck Lymph Dissection, Vascularized Lymph Node Transplantation
- Trial name
- NCT06815705
- Testing
- Vascularized lymphatic transplantation
- Where
- China
- Volunteers
- 23 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Lymphedema
Use of Reconstructive Microsurgery for the Treatment of Lymphedema
Lymphedema is a chronic condition characterized by the accumulation of lymphatic fluid in tissues, frequently resulting from oncological treatments, trauma, or cancer.
- Trial name
- NCT07889856
- Testing
- Surgery with and without the aid of Indocyanine Green (ICG)
- Where
- Italy
- Volunteers
- 15 people
- Sponsor
- Istituto Ortopedico Rizzoli
Lymphedema
Study of Lymphatic Dysfunction in Primary and Secondary Lymphedema
Lymphedema is a disorder of the lymphatic vascular system characterized by impaired lymphatic return and swelling of the extremities and accumulation of undrained interstitial fluid/lymph that results in fibrosis and adipose…
- Trial name
- LYMPHODYS (NCT05629026)
- Testing
- Micro-biopsies
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Toulouse
Postmastectomy Lymphedema Syndrome, Breast Cancer Surgery Pain
Deep Learning for Musculoskeletal Complications in Breast Cancer
Survival after breast cancer has increased due to early diagnosis and advances in treatment methods. Musculoskeletal problems related to cancer and its treatment constitute a significant part of the daily practice of physiatrists…
- Conditions
- Postmastectomy Lymphedema Syndrome, Breast Cancer Surgery Pain, Osteoporosis Secondary, Shoulder Adhesive Capsulitis
- Trial name
- NCT07236658
- Testing
- physical examination
- Where
- Turkey (Türkiye)
- Volunteers
- 133 people
- Sponsor
- Ankara Etlik City Hospital
Breast Neoplasms
Effect of Preoperative Exercise on the Prevention of Secondary Lymphedema in Breast Cancer Patients
Research purpose: Lymphedema is a very common complication in breast cancer patients. However, since there is currently no curable treatment, it is important to prevent and reduce the severity of lymphedema.
- Trial name
- NCT06421285
- Testing
- Aerobic exercise, Strength training, Flexibility exercise
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Asan Medical Center
Lymphedema, Lymphedema Arm
Screening For BCRL In Targeted Therapy For Breast Cancer
This a prospective, longitudinal study designed to track edema and Breast Cancer Related Lymphedema (BCRL) onset in breast cancer patients taking targeted therapy treatments for early and metastatic breast cancer.
- Conditions
- Lymphedema, Lymphedema Arm, Lymphedema of Upper Arm, Lymphedema of Upper Limb
- Trial name
- NCT05142800
- Testing
- Perometer, SOZO device
- Where
- United States
- Volunteers
- 261 people
- Sponsor
- Massachusetts General Hospital
Lymphedema
Sahid Method for Secondary Unilateral Lower Limb Lymphedema
Manual lymphatic drainage (MLD) is a non-invasive technique frequently used in the management of lymphedema. The Paloma Sahid Method is a patented approach to lymphatic drainage that combines specific manual and mechanical…
- Trial name
- NCT07198698
- Testing
- Paloma Sahid Method, a patented technique (PCT/CL2023/050061)
- Where
- Chile
- Volunteers
- 32 people
- Sponsor
- University Diego Portales
Secondary Lymphedema
Scapulothoracic Stabilization and Postural Training in Upper Extremity Lymphedema
This single-center randomized controlled trial aims to investigate the effects of adding scapulothoracic stabilization and postural training to standard lymphedema care in women with secondary upper extremity lymphedema following…
- Trial name
- NCT07697495
- Testing
- Complex Decongestive Therapy, Scapulothoracic Stabilization and Postural Training
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Toros University
Secondary Lymphedema
mRNA Therapy to Restore Lymphatic Flow in Secondary Lymphedema
Lymphedema is a common complication of breast cancer treatment, affecting approximately a quarter of patients. Those affected can have an uncomfortable, unsightly and sometimes functionally impaired limb prone to episodes of…
- Trial name
- LymphARN (NCT07793656)
- Testing
- APERNAVEC
- Where
- France
- Volunteers
- 9 people
- Sponsor
- University Hospital, Toulouse
Breast Cancer, Axillary Nodal Disease
IIT2023-09-Chung-UpfrontTAD: Upfront TAD/SNB in Patients With Breast Cancer With Nodal Metastases
The purpose of the study is to determine the recurrence rates and survival of patients with clinical T1-2N0 ER+/Her2- invasive breast cancer who have biopsy proven image detected nodal disease treated with upfront lumpectomy or…
- Conditions
- Breast Cancer, Axillary Nodal Disease, Female Breast Cancer, Axilla; Breast
- Trial name
- NCT06092892
- Testing
- Breast Surgery (BCS or mastectomy) with TAD/SNB, Adjuvant Radiation Therapy
- Where
- 3 sites in United States
- Volunteers
- 45 people
- Sponsor
- Alice Chung
Primary Lymphedema, Secondary Lymphedema
Biological Profile of Primary and Secondary Lymphedema: Inflammatory, Endothelial, Metabolic, Lymphatic, and Fibrotic Markers
This observational, cross-sectional study aims to characterize the biological profile of primary and secondary lymphedema by investigating five interconnected biological domains: T helper 2 (Th2)-related inflammation, endothelial…
- Trial name
- LYMPH5 (NCT07770399)
- Where
- Slovenia
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University Medical Centre Ljubljana
Lymphedema Arm, Lymphedema Due to Radiation
Effectiveness of a Therapeutic Exercise Program With Specific Upper Limb Exercises to Reduce Lymphedema and Neuropathy in Breast Cancer Patients: A Pre-post Study (LYNMA)
This study aims to evaluate the effectiveness of a therapeutic exercise program designed specifically for women with breast cancer.
- Conditions
- Lymphedema Arm, Lymphedema Due to Radiation, Lymphedema, Breast Cancer, Peripheral Neuropathy Due to Chemotherapy
- Trial name
- LYNMA (NCT07170631)
- Testing
- Therapeutic exercise
- Volunteers
- 30 people
- Sponsor
- Universitat Internacional de Catalunya
Lymphedema, Secondary, Lymphedema of Upper Limb
The N-LVA Study: RCT Comparing LVA vs. Sham Surgery in Cancer-related Lymphedema
The goal of this randomized controlled trial is to compare the effectiveness and cost-effectiveness of lymphaticovenous anastomosis (LVA) with sham surgery for patients suffering from unilateral cancer-related lymphedema in…
- Conditions
- Lymphedema, Secondary, Lymphedema of Upper Limb, Lymphedema, Lower Limb, Lymphedema Arm
- Trial name
- NCT06082349
- Testing
- Lymphaticovenous anastomosis
- Where
- 3 sites in Netherlands
- Volunteers
- 110 people
- Sponsor
- Maastricht University Medical Center
Lymphedema Arm
Lymphovenous Bypass Procedure for Secondary Prevention of Lymphedema in Breast Cancer
This study aims to evaluate the effectiveness of the Lymphovenous Bypass (LVB) procedure compared to physiotherapy alone as secondary prevention of lymphedema in breast cancer patients undergoing axillary lymph node dissection.
- Trial name
- NCT07233863
- Testing
- Lymphovenous bypass (LVB)
- Where
- Indonesia
- Volunteers
- 136 people
- Sponsor
- Dharmais National Cancer Center Hospital