Clinical trials: Lymphedema Lower Extremity
Limb Volume, Measuring Edema
Measuring Volume Using a 3D Scanner and iPad to Grade the Swelling of Legs
We used a new and easy-to-measure iPad 3D scanner to measure swelling in lower limbs because current technology is not easily available or affordable.
- Trial name
- NCT06944041
- Testing
- STO3 sensor (Structure Inc., Boulder, CO)
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- The RANE Center for Venous and Lymphatic Diseases at St. Dominic's Hospital
Lymphedema of Leg, Lymphedema Congenital
Physiological Study to Assess Mechanism of Action of MOBIDERM® in Lower-limb Lymphedema Patients
MOBIDERM® demonstrated his interest through clinical studies on the treatment of lower or upper limb lymphedema (Mestre et al 2017; Quéré et al. 2014).
- Conditions
- Lymphedema of Leg, Lymphedema Congenital, Lymphedema Primary, Lymphedema, Secondary
- Trial name
- ACTIODERM (NCT04252690)
- Testing
- MOBIDERM® autofit : auto-adjustable compression stocking
- Where
- France
- Volunteers
- 9 people
- Sponsor
- Thuasne
Compression; Vein, Venous Insufficiency
Digital Supported Compression Bandaging in Patients With Chronic Edema in the Lower Limbs
Patients with chronic edema of the lower limb referred to compression bandaging in a hospital setting will be invited to participate in the validation study of a novel sensor (CIMON), which have been developed for assessing the…
- Conditions
- Compression; Vein, Venous Insufficiency, Lymphedema of Leg, Digital Technology
- Trial name
- CIMON (NCT06438133)
- Testing
- CIMON, Sens Motion
- Where
- 5 sites in Denmark
- Volunteers
- 52 people
- Sponsor
- Carsten Bogh Juhl
Lymphedema, Secondary Lymphedema
Efficacy of Complete Decongestive Therapy for Limb Lymphedema: Response Profile and Predictive Modeling
Background: Complete decongestive therapy (CDT) is the standard treatment for lymphedema, but response varies by localization and laterality.
- Conditions
- Lymphedema, Secondary Lymphedema, Breast Cancer-Related Lymphedema, Upper Extremity Lymphedema
- Trial name
- LYMPH-PROG (NCT07878598)
- Testing
- Intensive phase of Complete Decongestive Therapy
- Where
- Russia
- Volunteers
- 150 people
- Sponsor
- Ryazan State Medical University
Gynecologic Cancer, Lymphedema of Leg
Home-based Intermittent Pneumatic Compression Therapy for Gynecologic Cancer
Investigators conducted a prospective study of cancer patients to investigate the efficacy, quality of life, satisfaction, and safety of a home-based intermittent pneumatic compression (IPC) device during the maintenance phase of…
- Trial name
- NCT05193357
- Testing
- home-based intermittent pneumatic compression (IPC) device
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- Samsung Medical Center
Chronic Leg Ulcer, Kaposi Sarcoma
Compression Therapy for Leg Ulcers and Kaposi Sarcoma in Western Kenya
The efficacy of locally sourced compression therapy in the management of chronic leg ulcers and Kaposi Sarcoma in western Kenya will be studied in a rural setting
- Conditions
- Chronic Leg Ulcer, Kaposi Sarcoma, HIV/AIDS and Infections
- Trial name
- NCT03404297
- Testing
- Locally sourced compression therapy
- Where
- 2 sites in Kenya
- Volunteers
- 30 people
- Sponsor
- Indiana University
Lymphedema
Ubenimex in Adult Patients With Lymphedema of The Lower Limb (ULTRA)
This proof-of-concept study is designed as a randomized, double-blind, placebo-controlled study comparing ubenimex at 150 mg, 3 times daily (total daily dose of 450 mg) with placebo for 6 months treatment period in patients with…
- Trial name
- NCT02700529
- Testing
- ubenimex
- Where
- 4 sites in United States, Australia
- Volunteers
- 54 people
- Sponsor
- Eiger BioPharmaceuticals
Lymphedema, Lymphedema of Leg
A Clinical Study to Evaluate the Effectiveness of a Novel Portable Non-Pneumatic Active Compression Device vs. an Advanced Pneumatic Compression Device for Treating Lower Extremity Lymphedema
To evaluate the Koya wearable device - a Novel Portable Non-Pneumatic Active Compression Device (NPCD) in contrast to an advanced pneumatic compression device (APCD)
- Conditions
- Lymphedema, Lymphedema of Leg, Chronic Venous Insufficiency, Venous Insufficiency
- Trial name
- TEAYS (NCT05507346)
- Testing
- Cross over Device (PCD or Dayspring - alternate to first group)
- Where
- United States
- Volunteers
- 121 people
- Sponsor
- Koya Medical, Inc.
Urogenital Cancer, Lower Limb Lymphedema
Lymphoedema and Nocturia/Nocturnal Polyuria After Pelvic LND for Urogenital Cancer
After the treatment of urogenital cancer, a person may develop lymphoedema of the leg(s) and/ or midline region. Clinical symptoms include abnormal tissue swelling, sensation of limb heaviness, erythema, pain, and impaired limb…
- Conditions
- Urogenital Cancer, Lower Limb Lymphedema, Nocturia, Nocturnal Polyuria
- Trial name
- UroLymph (NCT05300308)
- Testing
- usual care
- Where
- Belgium
- Volunteers
- 150 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Lymphedema Lower Extremity
Psychometric Properties of a Lymphedema-specific Quality of Life Questionnaire in Lower Limb Lymphedema
The goal of this observational study is to cross-validate the Lymphedema Functioning, Disability and Health Questionnaire for Lower Limb Lymphedema (Lymph-ICF-LL) in French and to investigate the responsiveness of the original…
- Trial name
- NCT07075549
- Testing
- Maintenance phase of Decongestive Lymphatic Therapy, Intensive phase of Decongestive Lymphatic Therapy
- Where
- 3 sites in Belgium, France
- Volunteers
- 451 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Lower Extremity Lymphedema
Aerobic Exercise Effects in Lower Extremity Lymphedema
Lower extremity lymphedema negatively affects patients' functional status, quality of life, and activities of daily living. Complete decongestive therapy (CDT) is considered the gold-standard conservative treatment for patients…
- Trial name
- NCT07726277
- Testing
- aerobic exercise program, complet decongestive therapy
- Volunteers
- 50 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Ovarian Cancer, Uterine Cancer
Gynecologic Cancer Lymphedema Questionnaire as a Clinical Care Tool to Identify Lower Extremity Lymphedema
The purpose of this study is to evaluate if the Gynecologic Cancer Lymphedema Questionnaire (GCLQ) truly detects symptoms or signs of lower extremity lymphedema in patients with diagnosed lower extremity lymphedema.
- Conditions
- Ovarian Cancer, Uterine Cancer, Vaginal Cancer, Lymphedema
- Trial name
- NCT00944944
- Testing
- limb volume measurements and GCLQ lymphedema symptom assessment questionnaire, GCLQ lymphedema symptom assessment questionnaire
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Lymphedema, Lymphedema Lower Extremity
Aerobic Training in Lower Extremity Lymphedema
This randomized controlled study aims to evaluate the effects of aerobic exercise training on gait, postural control, lower extremity muscle strength, and functional status in individuals with bilateral lower extremity…
- Trial name
- NCT07414615
- Testing
- Complex Decongestive Physiotherapy (CDP), Aerobic Training
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Bezmialem Vakif University
Lymphedema
Pedal Pump and Leg Lymphedema
Chronic lymphedema in the lower extremities is a common problem found in older adults that can result in cellulitis, poor wound healing, venous stasis ulcers, and other comorbidities.
- Trial name
- NCT06235463
- Testing
- Osteopathic Pedal Pump, Light Touch Treatment
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Rowan University