Clinical trials: Lymphedema of Limb
Primary Lower Limb Lymphedema, Secondary Lower Limb Lymphedema
Pilot Efficacy Study of the Stendo Pulsating Suit in Patient With Leg Lymphoedema
This study aims at evaluating the efficacy of the Stendo pulsating suit in patients with a leg lymphedema hospitalized for intensive Complex Decongestive Physiotherapy (CDP).
- Trial name
- NCT02234674
- Testing
- Current intensive CDP, intensive CDP where Stendo pulsating suit replaces pressotherapy
- Where
- France
- Volunteers
- 25 people
- Sponsor
- Stendo
Lymphedema, Lower Limb
The Effect of Dynamic Neuromuscular Stabilization Exercises in Patients With Lower Extremity Lymphedema
After lower extremity lymphedema, individuals physical activity levels and functionality remain very low. This decrease can cause balance problems over time.
- Trial name
- NCT06545383
- Testing
- Dynamic Neuromuscular Stabilization Exercises, Exercise
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Istanbul University - Cerrahpasa
Lower Limb Lymphedema
Use of the Unstable Shoes in Lower Limb Lymphedema.
Lymphedema is an external manifestation of lymphatic system insufficiency and deranged lymph transport. It is defined as accumulation in the extracellular space of protein-rich fluid, due to a mechanical failure of the lymphatic…
- Trial name
- NCT05996939
- Testing
- To compare the efficacy of unstable shoes with that of conventional sports shoes in people with lower-limb primary and secondary lymphedema.
- Volunteers
- 26 people
- Sponsor
- Universidad Europea de Madrid
Lymphedema, Genital Neoplasm
Lymphedema After Gyneco-oncologic Treatment
Trial developed to inventory the incidence of early and advanced stage lower limb lymphedema in patients diagnosed with and treated for gynaecologic cancer.
- Trial name
- Gynolymph (NCT05469945)
- Testing
- Compressive garments class II
- Where
- 2 sites in Belgium
- Volunteers
- 218 people
- Sponsor
- University Hospital, Ghent
Lymphedema of Leg
Hydrophobic Tubes for the Treament of Lower and Upper Limb Lymphedema
Lymphedema is a chronic condition causing fluid buildup in affected limbs. Traditional treatments often fall short, but subcutaneous implantation of hydrophobic silicone tubes shows promise, creating artificial drainage pathways.
- Trial name
- NCT05970068
- Testing
- implantation of hydrophobic tubes for edema fluid drainage, Best Medical Treatment
- Where
- Portugal
- Volunteers
- 20 people
- Sponsor
- Universidade do Porto
Ovarian Cancer, Uterine Cancer
Gynecologic Cancer Lymphedema Questionnaire as a Clinical Care Tool to Identify Lower Extremity Lymphedema
The purpose of this study is to evaluate if the Gynecologic Cancer Lymphedema Questionnaire (GCLQ) truly detects symptoms or signs of lower extremity lymphedema in patients with diagnosed lower extremity lymphedema.
- Conditions
- Ovarian Cancer, Uterine Cancer, Vaginal Cancer, Lymphedema
- Trial name
- NCT00944944
- Testing
- limb volume measurements and GCLQ lymphedema symptom assessment questionnaire, GCLQ lymphedema symptom assessment questionnaire
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Breast Cancer Lymphedema
Effect of the Axillary Lymphatic /Vein Reflux Ratio on Postoperative Upper Limb Edema and Dysfunction in Breast Cancer
The purpose of this study is to compare the difference in the incidence of upper limb edema and dysfunction between the Preponderant lymphatic reflux group (high ratio of axillary lymphatic reflux to axillary vein reflux) and the…
- Trial name
- PLEDGE-R (NCT05246592)
- Testing
- Branches Sparing, None Branches Sparing
- Where
- 3 sites in China
- Volunteers
- 258 people
- Sponsor
- Xiangyun Zong
Lymphedema, Lymphedema Lower Extremity
Aerobic Training in Lower Extremity Lymphedema
This randomized controlled study aims to evaluate the effects of aerobic exercise training on gait, postural control, lower extremity muscle strength, and functional status in individuals with bilateral lower extremity…
- Trial name
- NCT07414615
- Testing
- Complex Decongestive Physiotherapy (CDP), Aerobic Training
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Bezmialem Vakif University
Lymphedema, Lymphedema Arm
The Robot-LVA Study: Robot-assisted Microsurgical Lymphaticovenous Anastomosis in Breast Cancer-related Lymphedema
This study assesses the performance of robot-assisted microsurgery. Lymphaticovenous anastomosis (LVA) is the most difficult procedure in microsurgery at this moment.
- Conditions
- Lymphedema, Lymphedema Arm, Lymphedema of Upper Arm, Lymphedema of Upper Limb
- Trial name
- NCT06532955
- Testing
- Lymphaticovenous anastomosis using Microsure Motion Stabilizer, Lymphaticovenous anastomosis (manual)
- Where
- Netherlands
- Volunteers
- 60 people
- Sponsor
- Maastricht University Medical Center
Lower Extremity Lymphedema
Respiratory and Relaxation Training in Lower Extremity Lymphedema
This randomized controlled trial aims to investigate the effectiveness of respiratory and relaxation training added to standard complex decongestive therapy (CDT) on muscle oxygenation, functional capacity, and limb volume in…
- Trial name
- NCT07697482
- Testing
- Complex Decongestive Therapy, Respiratory and Relaxation Training
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Toros University
Lymphedema, Lymphedema Arm
Screening For BCRL In Targeted Therapy For Breast Cancer
This a prospective, longitudinal study designed to track edema and Breast Cancer Related Lymphedema (BCRL) onset in breast cancer patients taking targeted therapy treatments for early and metastatic breast cancer.
- Conditions
- Lymphedema, Lymphedema Arm, Lymphedema of Upper Arm, Lymphedema of Upper Limb
- Trial name
- NCT05142800
- Testing
- Perometer, SOZO device
- Where
- United States
- Volunteers
- 261 people
- Sponsor
- Massachusetts General Hospital
Breast Cancer Lymphedema, Post-Mastectomy Secondary Lymphedema
New Therapeutic Approach in Upper Limb Lymphedema Secondary to Breast Cancer: Activity-oriented Proprioceptive Antiedema Therapy (TAPA)
This study evaluates the effectiveness of an experimental proposal therapy for upper limb lymphedema secondary to breast called Activity-oriented proprioceptive antiedema therapy (TAPA) facing the consensual gold standard…
- Trial name
- NCT03762044
- Testing
- Activity-oriented Proprioceptive Antiedema Therapy (TAPA), Complete Decongestive Therapy (CDT)
- Where
- Spain
- Volunteers
- 51 people
- Sponsor
- Hospital Universitario Reina Sofia de Cordoba
Lower Extremity Lymphedema
Daphnetin Capsules for Lower Limb Lymphoedema Following Gynaecological Surgery
This clinical trial is designed to learn more about treating patients with lower limb lymphoedema following gynaecological surgery.
- Trial name
- NCT06329167
- Testing
- Daphnetin, Aescuven
- Where
- China
- Volunteers
- 100 people
- Sponsor
- The First Hospital of Jilin University
Lymphedema, Cancer
Complex Decongestive Physiotherapy Applied After Lymphovenous Anastomosis Surgery
Type of this study: Prospective randomized controlled study. The aim of our study is to compare patients with lymphedema who have undergone lymphovenous anastomosis surgery receiving Complex Decongestive Physiotherapy (CDP)…
- Trial name
- NCT06167993
- Testing
- Complex Decongestive Physiotherapy
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 26 people
- Sponsor
- Necmettin Erbakan University
Breast Cancer Surgery, Transcutaneous Electric Nerve Stimulation
Effects of Transcutaneous Electrical Nerve Stimulation on Breast Surgery
The aim of this randomized controlled trial was to evaluate the effects of transcutaneous electrical nerve stimulation (TENS) on postoperative pain, lymphedema development, shoulder range of motion, and quality of life in women…
- Trial name
- NCT06973265
- Testing
- TENS
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Seda Akutay
Endometrial Cancer, Lymphedema
Prevalence of Self Reported Lymphedema in Patients With Endometrial Cancer
The investigators are interested in understanding how the patient has been doing since their surgery for endometrial cancer and if they are experiencing any symptoms related to lymphedema (swelling) in the your lower body.
- Trial name
- NCT02912767
- Testing
- questionnaire
- Where
- United States
- Volunteers
- 625 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Lower Limb Lymphedema
Development of a Clinical Screening, Diagnostic and Evaluation Tool for Patients With Lower Limb Lymphedema: Aim 4
Research investigating measurement properties for evaluating the decongestive treatment effect on different edema characteristics (e.g.
- Trial name
- EvaLymph-Leg4 (NCT06038864)
- Testing
- 2 clinical evaluations with 1 month in between
- Where
- 2 sites in Belgium, Netherlands
- Volunteers
- 120 people
- Sponsor
- KU Leuven
Lymphedema
Effects of Inspiratory Muscle Training on Lymphedema
The aim of this study is to examine the effect of inspiratory muscle training on lymphedema volume, subcutaneous tissue thickness, upper extremity functionality and sleep quality in the treatment of upper extremity lymphedema.
- Trial name
- NCT06521268
- Testing
- Inspiratory muscle training, Decongestive treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Biruni University
Primary Lymphedema
Primary Lymphedema and Mutation CELSR1 (Cadherin EGF LAG Seven-pass G-type Receptor 1)
The investigators will describe the expression of mutation CELSR1 with codon stop and amino acids substitution mechanism in primary lymphedema, in both clinical examination and imaging exploration
- Trial name
- CELSR1 (NCT04919655)
- Where
- France
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Lower Limb Lymphedema, Urogenital Cancer
Lymphoedema and Nocturia/ Nocturnal Polyuria After Pelvic Lymph Node Dissection for Urogenital Cancer
After the treatment of urogenital cancer, a person may develop lymphoedema of the leg(s) and/ or midline region. Lymphoedema is the result of a dysfunction in the lymphatic system and is characterized by excessive retention of…
- Trial name
- UroLymph (NCT05266157)
- Testing
- Manual lymph drainage, Usual care
- Where
- Belgium
- Volunteers
- 30 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven