Clinical trials: Lymphedema of Upper Limb
Lymphedema of Upper Arm
Ultrasonographic Evaluation of Changes After Complex Decongestive Therapy
The aim of this study is to evaluate tissue changes via ultrasound after complex decongestive therapy.
- Trial name
- NCT04139291
- Testing
- Complex decongestive therapy phase 1
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Marmara University
Breast Cancer Lymphedema
Effect of ALND With Vein Branches Reservation on Postoperative Upper Limb Edema and Dysfunction in Breast Cancer
The purpose of this study is to compare the effects of axillary lymph node dissection with or without axillary vein branches reservation on the affected upper limb edema and dysfunction in breast cancer patients, and to explore…
- Trial name
- PLEDGE-Surgery (NCT05120180)
- Testing
- axillary lymph node dissection with vein branches reservation, axillary lymph node dissection without vein branches reservation
- Where
- 3 sites in China
- Volunteers
- 258 people
- Sponsor
- Xiangyun Zong
Lymphedema, Breast Cancer, Lymphedema of Upper Limb
Does Inclusion of Diaphragmatic Breathing Exercises in Complete Decongestive Therapy Provide Further Benefits in Patients With Breast Cancer Related Lymphedema
Complete decongestive therapy is proven to be effective in reducing lymphedema related symptoms such as swelling and pain. Breathing exercises, on the other hand, may also help managing lymphedema symptoms.
- Trial name
- NCT05754346
- Testing
- Complete Decongestive Therapy, Upper extremity exercises combined with diaphragmatic breathing exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Izmir Bakircay University
Lymphedema
Sahid Method for Secondary Unilateral Lower Limb Lymphedema
Manual lymphatic drainage (MLD) is a non-invasive technique frequently used in the management of lymphedema. The Paloma Sahid Method is a patented approach to lymphatic drainage that combines specific manual and mechanical…
- Trial name
- NCT07198698
- Testing
- Paloma Sahid Method, a patented technique (PCT/CL2023/050061)
- Where
- Chile
- Volunteers
- 32 people
- Sponsor
- University Diego Portales
Breast Cancer, Upper Extremity Lymphedema
Immunotherapy for the Treatment of Breast Cancer Related Upper Extremity Lymphedema (BCRL)
The purpose of this study is to assess the efficacy of QBX258, a compound developed by Novartis Corporation composed of two antibodies, in reducing arm volume excess in women with stage I-II breast cancer related lymphedema.
- Trial name
- NCT02494206
- Testing
- QBX258
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Breast Cancer (Locally Advanced or Metastatic), Lymphedema Arm
The Effect of Self-Management Interventions Among Patients With Breast Cancer Related-Lymphedema
To manage lymphedema, it's important to be aware of symptoms and risk factors, evaluate the afflicted extremity, prevent infections, care for the skin, protect the extremity from trauma, maintain a healthy weight, and exercise…
- Trial name
- (BCRL) (NCT07803549)
- Testing
- Self-management Interventions
- Where
- Jordan
- Volunteers
- 100 people
- Sponsor
- Al-Zaytoonah University of Jordan
Breast Cancer Related Lymphedema, Lymphedema, Secondary
Adjustable Compression Wrap Versus Compression Sleeve to Control Breast Cancer-related Lymphedema
This is a randomized clinical trial, in which the use of an Adjustable compression wrap as a compressive therapy to control the upper limb volume of with lymphedema women secondary to breast cancer will be investigated, in…
- Conditions
- Breast Cancer Related Lymphedema, Lymphedema, Secondary, Lymphedema of Upper Arm, Breast Neoplasms
- Trial name
- NCT04881604
- Testing
- Adjustable Compression Wrap, Compression Sleeve
- Where
- Brazil
- Volunteers
- 72 people
- Sponsor
- Instituto Nacional de Cancer, Brazil
Lymphedema
Lymphedema Study for Arm or Leg Lymphedema
This study compares the effectiveness of a study drug versus placebo in the treatment of lymphedema.
- Trial name
- NCT02257970
- Testing
- Ketoprofen
- Where
- United States
- Volunteers
- 117 people
- Sponsor
- Stanford University
Breast Cancer, Lymphedema
Effectiveness of Accelerated Intervention With Compression Sleeve in Mild and Moderate Breast Cancer-related Lymphedema
The purpose of this study is to determine whether accelerated treatment with custom-made compression sleeve is more effective than standard procedure in the treatment of mild and moderate arm lymphedema secondary to primary…
- Trial name
- NCT01954654
- Testing
- Custom-made compression sleeve and -gauntlet, Educational information, recommendation and instruction
- Where
- Denmark
- Volunteers
- 84 people
- Sponsor
- Mette Brodersen Jerver
Lymphedema
Identification of the Optimal Functional Lymphatic Vessel for Lymphaticovenous Anastomosis
The aim of this study is to further explore the optimal screening factors for functional lymphatic vessels in lymphaticovenous anastomosis in patients with lymphedema.
- Trial name
- NCT06191081
- Testing
- lymphaticovenous anastomosis
- Where
- China
- Volunteers
- 41 people
- Sponsor
- Taizhou Hospital
Limb Volume Measurement
The Validity and Reliability of Self Measurement of Upper Limb Volume
Lymphedema is a common, chronic, side effect resulting from the treatment of breast cancer.Insufficiency in the lymphatic system causes edema in the upper limb.
- Trial name
- NCT01225783
- Testing
- Self measurement of limb volume +water displacement
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Meir Medical Center
Invasive Breast Cancer, Ductal Carcinoma in Situ of the Breast
Axillary Reverse Mapping (ARM) Technique
The purpose of this pilot study is to compare a new surgical technique (axillary reverse mapping) to standard axillary surgery in patients diagnosed with invasive or in situ breast cancer.
- Trial name
- ARM (NCT03109522)
- Testing
- axillary reverse mapping (ARM), Standard axillary surgery (SLNB or ALND)
- Where
- 2 sites in Canada
- Volunteers
- 130 people
- Sponsor
- McMaster University
Breast Cancer Lymphedema
The Effect of Hand Exercises on Upper Limb Volume, Quality of Life, and Hand Function in Breast Cancer Survivors
The purpose of this study is to determine whether the addition of simple hand mobility and grip strengthening exercises to the usual care for upper extremity lymphedema will reduce limb volume and improve the quality of life…
- Trial name
- NCT05983380
- Testing
- Hand Mobility and Grip Strengthening Exercises, Usual Care
- Where
- 3 sites in United States
- Volunteers
- 50 people
- Sponsor
- Texas Woman's University
Breast Cancer, Breast Cancer Female
Factors Affecting Functionality in Breast Cancer Survivors
Breast cancer is the most frequent cancer type in women globally. In conjunction with the new developments, breast cancer survival has increased therefore the management of long-term complications has gained importance.
- Conditions
- Breast Cancer, Breast Cancer Female, Breast Cancer Lymphedema, Breast Carcinoma in Situ
- Trial name
- NCT04245657
- Testing
- Tissue Dielectric Constant Measurement, Muscle strength measurement, Hand-Grip Strength Measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 111 people
- Sponsor
- Izmir Bakircay University
Lymphedema Arm
Mobile Self-Management Training for Lymphedema Prevention
Breast cancer is the most common cancer among women in the world and in our country and affects women negatively in many ways. Depending on the treatment, patients experience serious problems.
- Trial name
- lymphedema (NCT07043140)
- Testing
- mobile application
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Inonu University
Lymphedema, Secondary Lymphedema
Efficacy of Complete Decongestive Therapy for Limb Lymphedema: Response Profile and Predictive Modeling
Background: Complete decongestive therapy (CDT) is the standard treatment for lymphedema, but response varies by localization and laterality.
- Conditions
- Lymphedema, Secondary Lymphedema, Breast Cancer-Related Lymphedema, Upper Extremity Lymphedema
- Trial name
- LYMPH-PROG (NCT07878598)
- Testing
- Intensive phase of Complete Decongestive Therapy
- Where
- Russia
- Volunteers
- 150 people
- Sponsor
- Ryazan State Medical University
Lymphedema of Upper Arm, Breast Cancer
Noninvasive Assessment of Lymphedema Among Breast Cancer Survivors
This proof of concept study will evaluate the ability of a new, ultrasound based technology called Bullseye Constructive Shearwave Interference (CSI) (trade name, Bullseye Elasticity Quantification) to measure lymphedema of the…
- Trial name
- NCT05278871
- Testing
- Constructive Shearwave Interference (CSI)
- Where
- 2 sites in United States
- Volunteers
- 21 people
- Sponsor
- Microelastic Ultrasound Systems Inc
Lymphedema of Upper Limb
MRL in the Upper Extremity
Objective: The aim of this study is to examine the feasibility and applicability of the MRL protocol for the upper extremity in Maastricht University Medical Center, and to examine the differences of the lymphatic system between…
- Trial name
- NCT04575636
- Testing
- Magnetic Resonance Lymphography
- Where
- Netherlands
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Breast Cancer, Physical Activity
Supervised Resistance TRaining amONG Women at Risk of Breast Cancer Related Lymphedema
Breast cancer (BC) is the most common neoplasm in Chile, and its medical treatment leads to high survival. One-third of survivors will develop BC-related lymphedema.
- Conditions
- Breast Cancer, Physical Activity, Lymphedema of Upper Arm
- Trial name
- STRONG-B (NCT04821609)
- Testing
- Resistance Training
- Where
- Chile
- Volunteers
- 106 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Breast Cancer, Shoulder Dysfunction
Exercise Prehabilitation of Breast Cancer
This prospective prehabilitation trial evaluated the effectiveness of an individualized exercise program initiated before breast cancer surgery and maintained for 12 months.
- Conditions
- Breast Cancer, Shoulder Dysfunction, Quality of Life, Postoperative Recovery
- Trial name
- Prehab of BC (NCT07240584)
- Testing
- Exercise-Based Prehabilitation Program
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- University of Health Sciences Balikesir Hospital Eduation and Research