Clinical trials: MANDIBLE
Partial-edentulism
Clinical Evaluation of NiTiDent Tuah Porous NiTi Dental Implants
The purpose of this prospective, open-label, randomized, double arm multicenter study is to evaluate the safety and clinical performance of a newly developed NiTiDent Tuah porous NiTi dental implant (from Nitium Technology Sdn…
- Trial name
- NCT04618055
- Testing
- NiTiDent Tuah Porous NiTi Dental Implants, Control Dental Implant Systems
- Where
- 3 sites in Malaysia
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Nitium Technology Sdn Bhd
Horizontal Bone Augmentation
A 1-year Clinical Investigation on the the CREOS™ XENOGAIN Bone Graft SUBSTITUTE
This clinical investigation is a prospective, multi-centre study to evaluate bone gain after horizontal augmentation using creos xenogain bone graft substitute.
- Trial name
- NCT03028922
- Testing
- creos xenogain
- Where
- 6 sites in Germany, Italy and 1 more
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Nobel Biocare
Partial Edentulism, Tooth Disease
TM vs TSV Implants Loaded Early vs Conventional in Anterior and Posterior Areas
Randomized-controlled, multicenter study of Trabecular Metal (TM) and Tapered Screw-Vent (TSV) dental implants loaded early in maxillary and mandibular sites.
- Trial name
- TMEL (NCT02158377)
- Testing
- Trabecular metal dental implants (TM), Tapered screw-vent implants (TSV)
- Where
- 3 sites in Germany
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- ZimVie
Dental Anesthesia, Anesthesia, Local
Study of OraVerse® for Safety and Efficacy in Pediatric Dental Patients
The purpose of this study is to determine whether OraVerse is safe and effective for the reversal of dental anesthesia in children 2 to 5 years of age weighing at least 10 kg.
- Conditions
- Dental Anesthesia, Anesthesia, Local, Anesthesia, Reversal
- Trial name
- NCT01474382
- Testing
- OraVerse
- Where
- 7 sites in United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Novocol Pharmaceutical of Canada, Inc.
Obstructive Sleep Apnea
Validation of an Integrated Digital Solution (SUNrise®) Versus Polysomnography for Obstructive Sleep Apnea Diagnosis
Validation of an integrated digital solution (SUNrise®) of mandibular movement automatic analysis by artificial intelligence versus polysomnography for obstructive sleep apnea diagnosis: a prospective, randomized, parallel-arm…
- Trial name
- SUNSAS (NCT05057975)
- Testing
- Sunrise, polysomnography
- Where
- 19 sites in France
- Volunteers
- 848 people, healthy volunteers welcome
- Sponsor
- Sunrise
Impacted Third Molar, Postoperative Pain
Natural Enzyme Mouthwash After Third Molar Surgery
This clinical study investigates whether a natural enzyme-containing mouthwash (ORAL7®) can improve healing, pain and mouth opening after the surgical removal of impacted lower wisdom teeth (mandibular third molars), compared to…
- Conditions
- Impacted Third Molar, Postoperative Pain, Trismus, Wound Healing
- Trial name
- NCT07627945
- Testing
- ORAL7® Mouthwash, 0.2% Chlorhexidine Gluconate Mouthwash
- Where
- Malaysia
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- MBD MARKETING SDN. BHD.
Temporomandibular Disorder, Motor Imagery
Assessing Motor Imagery Ability of Tongue and Mouth in Subjects With and With no Temporomandibular Disorders
Temporomandibular disorder (TMD) is the symptomatic expression of a muscular or an articular impairment at the manducatory tract. TMD affects between 30 to 65% of the population with a higher prevalence for young women.
- Trial name
- TMIQ (NCT04102306)
- Testing
- reliability and validity construct of the TMIQ
- Where
- France
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Cabinet de Kinesitherapie SCM Saint-Alexandre
Deficiency of Alveolar Ridge (Disorder), Alveolar Bone Grafting
Safety and Efficacy Evaluation of the Ivory Dentin Graft Device
Ivory Dentin Graft is at least as good as the competitor treatment group (OsteoBiol Gen Os) for alveolar ridge preservation following tooth extraction.
- Conditions
- Deficiency of Alveolar Ridge (Disorder), Alveolar Bone Grafting, Mandibular Prosthesis User
- Trial name
- IvoryGraft (NCT03150472)
- Testing
- Graft Matrix
- Where
- Israel
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Ivory Graft Ltd.
Pain
Study to Investigate the Analgesic Efficacy of a Single Dose of AZD1940
The primary aim of this study is to investigate if AZD1940 can relieve the pain induced by the surgical removal of one lower wisdom-tooth.
- Trial name
- NCT00659490
- Testing
- AZD1940, Naproxen
- Where
- United States
- Volunteers
- 151 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Edentulous
All-On-4® Treatment Concept
Indication : edentulous patients To evaluate and compare the marginal bone level change around tilted and straight NobelActive implants placed in healed sites with All-on-4-treatment concept after immediate function supporting…
- Trial name
- NCT02186912
- Testing
- Nobel Active, Nobel Procera IBO
- Where
- Germany
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Nobel Biocare
Partial Edentulism, Complete Edentulism
Immediate Function of NobelSpeedy Shorty and Brånemark System® Mk III Shorty Implants in Daily Use
The aim of this study was to evaluate the 7 mm long implants NobelSpeedy Shorty and Brånemark System Mk III Shorty: by determining the marginal bone remodeling, implant survival rate, soft tissue health and maintenance.
- Trial name
- NCT02180230
- Testing
- Shorty implants
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Nobel Biocare
Edentulous
A Clinical Evaluation of NobelProcera Implant Bar Overdenture
AN OPEN 5-YEAR PROSPECTIVE, CLINICAL MULTI-CENTER STUDY on NobelProcera Implant Bar Titanium with Locator attachment and related Overdenture on 4 NobelReplace implants with conical connection (CC) in the mandible/maxilla.
- Trial name
- NCT01720420
- Testing
- NobelReplace CC, NobelProcera Implant Bar
- Where
- 7 sites in Germany, Italy
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Nobel Biocare
Dental Research, Orthodontics
Treatment of the Mandibular Dental Crowding With and Without Corticotomy Surgery
The use of corticotomy surgery in addition to orthodontic standard treatment could accelerate the treatment. Corticotomy involves vertical interdental incisions of the gingiva and the bone with a very low thickness.
- Conditions
- Dental Research, Orthodontics, Surgery, Oral, Maxillofacial Surgery
- Trial name
- CORTICO (NCT03967002)
- Testing
- Test group with corticotomy surgery
- Where
- Switzerland
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Ardentis Cliniques Dentaires
Partial Denture
A Study to Determine the Efficacy of a Denture Adhesive to Seal Out Food Particles From Under the Mandibular Partial Denture
The objective of this study is to evaluate the effectiveness of two denture adhesives at keeping food particles (seeds) from becoming trapped underneath partial denture(s).
- Trial name
- NCT05908890
- Testing
- Experimental Denture Adhesive, Fixodent True Feel Denture Adhesive
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Procter and Gamble
Pain
Study to Investigate the Analgesic Efficacy of a Single Dose of AZD1386
The primary aim of this study is to investigate if AZD1386 can relieve the pain induced by the surgical removal of one lower wisdom-tooth.
- Trial name
- NCT00672646
- Testing
- AZD1386, Naproxen
- Where
- United States
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Aging, Healthy
The Evaluation of Efficacy and Safety of Stylage® XL Lidocaïne for the Restoration and/or Augmentation of Facial Volume
Stylage® XL Lidocaïne is a CE-marketed hyaluronic acid gel indicated for the restoration or augmentation of facial volume by injection into the deep dermis or subcutaneously.
- Trial name
- BeautyVolume (NCT04166292)
- Testing
- Stylage® XL Lidocaïne
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Laboratoires Vivacy
Surgery--Complications, Molar, Third
Probiotic Intervention After Surgical Removal of Mandibular Third Molars
Single-center, double-blind, randomized trial of probiotics L. plantarum KABP-051 (CECT7481) and L. brevis KABP-052 (CECT7480) taken twice daily for 7 days after surgical removal of both mandibular 3rd molars.
- Trial name
- NCT04203771
- Testing
- Probiotic AB-DENTALAC, Surgical removal of mandibular third molars at baseline, Ibuprofen
- Where
- Spain
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- AB Biotics, SA
TMJ Disc Disorder, TMJ Pain
MDR-JuggerKnot Mini Soft Anchor in Maxillofacial TMJ
The objective of this retrospective consecutive series PMCF study is to collect data confirming safety, performance and clinical benefits of the JuggerKnot Mini Soft Anchor (implant and instrumentation) when used for soft tissue…
- Conditions
- TMJ Disc Disorder, TMJ Pain, TMJ Sounds on Opening/Closing the Jaw, TMJ Disease
- Trial name
- NCT04033692
- Testing
- JuggerKnot Mini Soft Anchor
- Volunteers
- healthy volunteers welcome
- Sponsor
- Zimmer Biomet
Tooth Loss
Performance Evaluation of FullCeram Implants in Single Tooth Gaps
Straumann Monotype FullCeram implants serve as a suitable alternative for implant therapy especially in the aesthetic zone The survival rate of Straumann Ceramic implants should be at least 85% (max 6 implant losses out of 40…
- Trial name
- NCT02163395
- Testing
- FullCeram implant
- Where
- 3 sites in Germany
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Institut Straumann AG
Edentulous or Failing Dentition Mandible
The TREFOIL Concept 5 Year Clinical Investigation
Prospective, single cohort, multi-center study evaluating the TREFOIL concept for the treatment of edentulous or patients with failing mandibular dentition over 5 years. 90 patients (15 per centre) will be included.
- Trial name
- NCT02940353
- Testing
- TREFOIL concept
- Where
- 5 sites in United States, Australia and 3 more
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Nobel Biocare