Clinical trials: MEN1
Gastrin-Producing Neuroendocrine Tumor, Lung Carcinoid Tumor
Pazopanib Hydrochloride in Treating Patients With Advanced Neuroendocrine Cancer
This phase II trial studies how well pazopanib hydrochloride works in treating patients with advanced neuroendocrine cancer. Pazopanib hydrochloride may stop the growth of tumor cells by blocking some of the enzymes needed for…
- Conditions
- Gastrin-Producing Neuroendocrine Tumor, Lung Carcinoid Tumor, Metastatic Digestive System Neuroendocrine Tumor G1, Multiple Endocrine Neoplasia Type 1
- Trial name
- NCT00454363
- Testing
- Laboratory Biomarker Analysis, Pazopanib Hydrochloride, Pharmacological Study
- Where
- 3 sites in United States
- Volunteers
- 52 people
- Sponsor
- National Cancer Institute (NCI)
Weight Loss, Men
A Novel Approach to Reducing Adiposity Among Young Men
The purpose of this research study is to find out whether a primarily self-guided program can produce changes in weight, body fat and cardiovascular risk among young men.
- Conditions
- Weight Loss, Men, Lifestyle Risk Reduction, Cardiovascular Diseases
- Trial name
- NCT04267263
- Testing
- Self-guided lifestyle intervention
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Virginia Commonwealth University
Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia
A Study to Find the Highest Dose of SNDX-5613 (Revumenib) as a Treatment Option After Hematopoietic Stem Cell Transplant in Children With Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, and Mixed Phenotype Acute Leukemia
This phase I trial tests the safety, best dose, and effectiveness of revumenib given as maintenance therapy after standard hematopoietic stem cell transplant (HSCT) in patients with acute lymphoblastic leukemia, acute myeloid…
- Conditions
- Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, Childhood Acute Lymphoblastic Leukemia, Childhood Acute Myeloid Leukemia
- Trial name
- NCT07498465
- Testing
- Biospecimen Collection, Bone Marrow Aspiration, Bone Marrow Biopsy
- Sponsor
- Children's Oncology Group
Eating Disorder
Reducing Eating Disorder Risk Factors Among College-Aged Males
The purpose of the present study was to investigate the acceptability and efficacy of a cognitive dissonance-based (DB) intervention in reducing eating disorder and muscle dysmorphia risk factors in men with body dissatisfaction.
- Trial name
- NCT03013244
- Testing
- The Body Project: More Than Muscles
- Where
- United States
- Volunteers
- 112 people
- Sponsor
- Florida State University
Obesity
Low Carb Diets & Exercise for Cardiovascular Disease (CVD) Reduction
The purposes of this study are: To investigate the effects of a 6 month low carbohydrate diet in obese men on markers of heart health including blood fats, blood clotting factors, inflammatory markers and levels of body fat.
- Trial name
- NCT01176084
- Testing
- low carbohydrate diet, low carbohydrate diet and exercise
- Where
- United Kingdom
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of Surrey
Healthy
Effects of Growth Hormone Administration on Muscle Strength and Body Composition in Men Over 50 Years Old
The growth hormone (GH) secretion declines gradually with age, with studies demonstrating a progressive reduction of 14% secretion per decade of life beginning in the second decade.
- Trial name
- NCT01853566
- Testing
- growth hormone
- Where
- Brazil
- Volunteers
- 13 people
- Sponsor
- Universidade Federal do Rio de Janeiro
Men, Diet Modification
Dietary Guide in Active Older Adult Men
The present study aimed to determine the effects of negative-calorie diet supplemented with exercise, on weight loss and lipid profile, and to compare its efficiency with low-calorie diet with exercise among elderly adult men…
- Conditions
- Men, Diet Modification, Obesity, Overweight
- Trial name
- NCT03082807
- Testing
- NCDsport, LCDsport
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- P.L.Shupik National Medical Academy of Post-Graduate Education
Testosterone, Androgens
Comparison Between Calculated Bioavailable Testosterone Level With Radio-immunoassay Result.
Currently, the gold standard to obtain bioavailable testosterone results is radioimmunoassay (RIA). However, this assay requires specific equipment.
- Trial name
- TESTOBIO (NCT04807231)
- Testing
- Blood withdrawal
- Where
- France
- Volunteers
- 270 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Cardiovascular Diseases
Effects of the Mediterranean Diet on Cardiovascular Risk Profile in Men and Women
The purpose of this study is to document differences between men and women in changes in metabolic variables associated with cardiovascular risk in response to a 4 weeks isocaloric controlled nutritional intervention based on the…
- Trial name
- ALIMED (NCT01293344)
- Testing
- Controlled nutritional intervention based on the Mediterranean diet
- Where
- Canada
- Volunteers
- 70 people
- Sponsor
- Laval University
Menin Inhibitors, Acute Leukemia
A Real-world Study on the Efficacy and Safety of Menin Inhibitors as Maintenance After Allo-HSCT
The objective of this observational study is to evaluate the efficacy and safety of menin inhibitor maintenance therapy in patients with acute leukemia who have undergone allogeneic hematopoietic stem cell transplantation…
- Conditions
- Menin Inhibitors, Acute Leukemia, Post Hematopoietic Stem Cell Transplantation, Maintenance Therapy
- Trial name
- NCT07559695
- Where
- China
- Volunteers
- 20 people
- Sponsor
- The First Affiliated Hospital of Soochow University
Androgenic Alopecia
Effect of Pumpkin Seed Oil on Hair Growth in Men With Androgenetic Alopecia
Androgenic alopecia is the most common cause of hair loss in men. Finasteride and minoxidil are available in treatment of androgenetic alopecia, although the former causes decreased libido or ejaculate volume, erectile…
- Trial name
- NCT01852487
- Testing
- 400mg /day during 6 months
- Where
- South Korea
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Dream Plus
Depressive Symptoms, Anxiety Generalized
Mobile Phone App for Depression and Anxiety in Young Men Who Are Attracted to Men
The purpose of this study is to determine whether a mobile phone application ("app") for symptoms of depression and anxiety is practical and acceptable to young men who are attracted to men, and whether it reduces their anxiety…
- Trial name
- TODAY! (NCT02072252)
- Testing
- Mobile Phone Application
- Where
- United States
- Sponsor
- Northwestern University
Hypertension, Aging
Wild Blueberries and Cardiovascular Health in Middle-aged/Older Men and Postmenopausal Women
Cardiovascular disease (CVD) is the leading cause of morbidity and mortality worldwide. Aging is the primary risk factor for CVD, in large part due to adverse modifications to the arteries.
- Conditions
- Hypertension, Aging, Endothelial Dysfunction, Men
- Trial name
- WB2020 (NCT04530916)
- Testing
- Blueberry Powder
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Colorado State University
Obesity, Gender
Work-Related Effects of Heat, Activity, and Fat in Middle Aged Men
Obesity is associated with many undesirable health effects and disease, and middle age is associated with increased risk for disease.
- Conditions
- Obesity, Gender, Problem of Aging
- Trial name
- NCT02532725
- Testing
- Cardiopulmonary Exercise Stress Test, Climatic-Controlled Cardiopulmonary Exercise Stress Test, Body Composition Evaluation
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Freeman-Sheldon Research Group, Inc.
Smoking Cessation
Yoga for Men Attempting Smoking Cessation
The purpose of this pilot study is to examine the feasibility and preliminary efficacy of a quit-smoking program that combines behavioral therapy with either yoga, or a health \& wellness program that serves as a contact control.
- Trial name
- NCT02055326
- Testing
- Cognitive Behavioral Therapy for Smoking Cessation, Yoga, Health & Wellness
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- The Miriam Hospital
Vitamin D Deficiency
How Much Vitamin D is Required to be Protective Against Deficiency During the Winter Months?
Vitamin D is essential to bone health. In Canada, it is obtained by sunlight exposure of the skin (between April and October) or by a few foods such as fatty fish, eggs or fortified milk and margarine.
- Trial name
- NCT01437696
- Testing
- Vitamin D
- Where
- Canada
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- McGill University
Vasomotor Symptoms as a Sex Hormone-dependent Disorder in Women and Men, Hot Flashes
A Study to Learn More About How the Study Treatment Elinzanetant (or BAY3427080) Moves Into, Through and Out of the Body, How Safe it is and How it Affects the Body After Taking Single and Multiple Doses in Healthy Women Aged 40 to 65 Years
Researchers are looking for a better way to treat men and women with vasomotor symptoms, a condition of having hot flashes caused by hormonal changes.
- Conditions
- Vasomotor Symptoms as a Sex Hormone-dependent Disorder in Women and Men, Hot Flashes, Healthy Volunteers
- Trial name
- NCT05381142
- Testing
- Elinzanetant (BAY3427080)
- Where
- China
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Bayer
Hyperglycemia, Hyperlipidemia
Healthy Volunteers Study of the Effects of Olanzapine and Ziprasidone
Primary Aim: To test the acute effects of olanzapine or ziprasidone administration, in comparison to placebo, on insulin sensitivity in antipsychotic-naïve healthy young men, measured as whole-body dextrose infusion rates…
- Trial name
- NCT00910988
- Testing
- Olanzapine, Ziprasidone
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Men, Health Behavior
POWERPLAY Phase 2: Development and Evaluation in Male-dominated Workplaces
With funding from the Alberta Ministry of Labour (Grant #095244772), a program called POWERPLAY (www.powerplayatwork.com), designed to promote men's health at work, will be evaluated in workplaces in Alberta.
- Conditions
- Men, Health Behavior, Mental Health Wellness 1, Health Knowledge, Attitudes, Practice
- Trial name
- NCT03781453
- Testing
- POWERPLAY
- Where
- 3 sites in Canada
- Volunteers
- 498 people, healthy volunteers welcome
- Sponsor
- Joan Bottorff
Neuroendocrine Tumors, Von Hippel-Lindau Syndrome
Evaluation of 68Gallium-DOTATATE PET/CT for Detecting Neuroendocrine Tumors
Background: Neuroendocrine tumors (NETs) are rare but have been more common over the past decade. The only treatment for NETs is surgery, but most are found when they are too advanced for surgery.
- Conditions
- Neuroendocrine Tumors, Von Hippel-Lindau Syndrome, Hippel-Lindau Disease
- Trial name
- NCT01967537
- Testing
- 68Gallium DOTATATE, Radio-guided surgery
- Where
- United States
- Volunteers
- 341 people
- Sponsor
- National Cancer Institute (NCI)