Clinical trials: MGD-Meibomian Gland Dysfunction
Meibomian Gland Dysfunction
Fast Infrared Meibography (Photography)
Infrared meibography is a useful technique in the evaluation of meibomian gland disease (MGD). MGD is a major cause of dry eye symptoms, affecting a large number of patients seen in the Corneo-Plastic Unit (CPU).
- Trial name
- NCT02596919
- Testing
- photography
- Where
- United Kingdom
- Volunteers
- 15 people
- Sponsor
- Queen Victoria Hospital NHS Foundation Trust
Dry Eye
Transcutaneous Auricular Vagus Nerve Stimulation in Dry Eye Disease With Meibomian Gland Dysfunction
Objective: To evaluate the effect of transcutaneous auricular vagus nerve stimulation (taVNS) for the patients with dry eye disease with meibomian gland dysfunction. Methods: We enrolled 270 patients at Beijing Tongren Hospital.
- Trial name
- NCT06544447
- Testing
- taVNS, Hyaluronic acid eye drops
- Where
- China
- Volunteers
- 135 people
- Sponsor
- Beijing Tongren Hospital
Dry Eye
Comparing Efficacy of Tea Tree Oil Versus Topical Azithromycin in Treating Dry Eye
This study aims to compare the effects of azithromycin and tea tree oil on the clinical outcomes and inflammatory profile of patients with MGD-associated DED.
- Trial name
- NCT06921525
- Testing
- Tea Tree Oil Topical Application Oil, Azithromycin Ophthalmic Solution
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Ehab Mohamed Elsayed Mohamed Saad
Meibomian Gland Dysfunction
Effect of Eye Make up on Ocular Surface
The aim of this study is to compare the degree of tear film instability and severity of meibomian gland loss between subjects who use eyeliner, mascara, a combination of both and those who do not use eyeliner.
- Trial name
- NCT04478955
- Testing
- Schirmer test
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Erol Olcok Corum Training and Research Hospital
Meibomian Gland Dysfunction
Evaluation of the LipiFlow System With a New Activator
Minimum 50 eyes and up to 100 eyes will be treated in this prospective, open-label clinical study. The investigator or designee will perform LipiFlow treatment with the Activators LFD-2100 on both eyes of a subject.
- Trial name
- NCT04500821
- Testing
- Activator LFD-2100
- Where
- 3 sites in United States
- Volunteers
- 44 people
- Sponsor
- Johnson & Johnson Surgical Vision, Inc.
Dry Eye, Meibomian Gland Dysfunction
To Evaluate the Efficacy of Diquafosol Sodium in the Treatment of MGD in Different Treatment Pattern
MGD is a chronic, diffuse abnormality of the meibomian glands, commonly characterized by terminal duct obstruction and/or qualitative/quantitative changes in the glandular secretion.
- Trial name
- NCT05383612
- Testing
- Warm compresses, 3% Diquafosol Sodium Eye Drops
- Where
- China
- Volunteers
- 140 people
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Dry Eye Syndrome
Evaluation of Factors Affecting the Tear-film Lipid Layer Thickness
In this study, the investigators aim to determine the effects of age, sex, history of ocular surgery and contact lens use, and ocular surface and meibomian gland parameters on the lipid layer thickness (LLT) in normal subjects…
- Trial name
- NCT02645045
- Where
- South Korea
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Meibomian Gland Dysfunction
Eyelid Warming Technology for Meibomian Gland Dysfunction
Meibomian gland dysfunction (MGD), an extremely common clinical condition (seen in more than half of some Asian populations), affects the lipid producing meibomian glands in the eyelids.
- Trial name
- NCT01448369
- Testing
- Blephasteam, EyeGiene, Hot compresses
- Where
- Singapore
- Volunteers
- 75 people
- Sponsor
- Singapore National Eye Centre
Dry Eye Disease (DED), Meibomian Gland Dysfunction (Disorder)
Effect of Oral Isotretinoin on Ocular Surface and Meibomian Glands
The aim of the study was to evaluate meibomian gland morphology using non-contact meibography and ocular surface changes in patients with acne vulgaris treated with isotretinoin as indicators of dry eye, which is known to be a…
- Conditions
- Dry Eye Disease (DED), Meibomian Gland Dysfunction (Disorder), Acne Vulgaris
- Trial name
- NCT07753811
- Testing
- isotretinoin
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Benha University
Dry Eye, Meibomian Gland Dysfunction
Crosslinked Hyaluronic Acid With Liposomes and Crocin in Dry Eye
A total of 50 eyes were analyzed (25 patients). The subjects selected were over 18 years of age. No gender distinction was made in the choice of subjects. All subjects were carriers of silicone hydrogel contact lenses.
- Conditions
- Dry Eye, Meibomian Gland Dysfunction, Dry Eye Syndromes
- Trial name
- NCT03617315
- Testing
- Hylauronic Acid
- Where
- Spain
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Seville
Meibomian Gland Dysfunction
The Influence of Meibomian Gland Expression on Corneal Aberrations in MGD Patients
To evaluate the influence of corneal-aberrations before and after the meibomian gland thermal massage treatment.
- Trial name
- NCT05028491
- Where
- China
- Volunteers
- 62 people
- Sponsor
- Wenzhou Medical University
Meibomian Gland Dysfunction
EyeBag Effectiveness in Meibomian Gland Dysfunction
Meibomian gland dysfunction (MGD) is a common condition that causes the secretion from meibomian glands in the eyelids to become blocked. Normally, the secretion helps to maintain a healthy tear film.
- Trial name
- MGD (NCT01870180)
- Testing
- EyeBag
- Where
- United Kingdom
- Volunteers
- 18 people
- Sponsor
- Aston University
GVHD, Meibomian Gland Dysfunction (Disorder)
Autologous Serum Obtained by a Closed-Circuit Collection Device
Autologous serum eye drops (ASED) are an established therapy for ocular surface diseases; however, their preparation can be costly and may not be available due to the need for germ-free conditions.
- Conditions
- GVHD, Meibomian Gland Dysfunction (Disorder), Stevens-Johnson Syndrome, Limbal Keratoconjunctivitis
- Trial name
- NCT07014059
- Testing
- Autologous Serum 20%
- Where
- Brazil
- Volunteers
- 16 people
- Sponsor
- GIANCARLO FATOBENE
Meibomian Gland Dysfunction
Intense Pulsed Light Therapy in Meibomian Gland Dysfunction
to evaluate the effect of intense pulsed light on resistant patients with Meibomian gland dysfunction
- Trial name
- NCT04904874
- Testing
- intense pulsed light
- Where
- Kuwait
- Volunteers
- 50 people
- Sponsor
- Dar Al Shifa Hospital
Dry Eye Syndromes
Efficiency and Changes of Cytokines Expression in Tear After Intense Pulsed Light Treating Dry Eye Disease
The aim of the current study is to investigate changes of tear cytokines levels as well as the efficacy and the reduction of demodex infestation after OPT IPL treatment in patients with meibomian gland dysfunction-Associated…
- Trial name
- NCT04165785
- Testing
- OPT IPL, MGX
- Where
- China
- Volunteers
- 64 people
- Sponsor
- First Affiliated Hospital of Harbin Medical University
Contact Lens Discomfort, Meibomian Gland Dysfunction
Meibomian Gland Dysfunction Management
The purpose of this study is to compare electronic debridement of the eyelid margin (BlephEx) to manual debridement of the eyelid margin as treatment options for patients intolerant to contact lens wear consequent to Meibomian…
- Trial name
- NCT03652337
- Testing
- BlephEx, Manual debridement
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of the Incarnate Word
Dry Eye, Meibomian Gland Dysfunction
IPL and MGX Versus MGX Alone in the Treatment of Dry Eye Disease Secondary to MGD
The aim of the current study is to examine the contribution of intense pulsed light (IPL) for relieving signs and symptoms of dry eye due to meibomian gland dysfunction.
- Trial name
- NCT03265652
- Testing
- Intense Pulsed Light (IPL) therapy
- Where
- Israel
- Volunteers
- 24 people
- Sponsor
- Lumenis Be Ltd.
Dry Eye Syndromes
Treatment Regimens in Meibomian Gland Dysfunction
This study seeks to explore the relevance of inflammation in dry eye patients with MGD and compare the efficacy of LipiFlow treatment followed by lid hygiene and lubricant treatment with Systane Ultra or LipiFlow treatment…
- Trial name
- NCT05594745
- Testing
- Lifitegrast Ophthalmic, Systane Free, Lipiflow
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Tauber Eye Center
Moderate and Severe Meibomiang Gland Dysfunction (Stage 3 or Stage 4 Meibomiang Gland Dysfunction)
Changes of Keratometric Value and Ocular Aberration After Treatment of Meibomian Gland Dysfunction
Ocular aberration may play a role in determining optical quality. Recently performed study reported that ocular aberration of preocular tear film would be important factor in not only diagnosing the dry eye but also determining…
- Trial name
- NCT01692665
- Sponsor
- Yonsei University
Meibomian Gland Dysfunction
Effect of Meibomian Gland Probing on Ocular Surface in Ocular Rosacea
Meibomian glands (MG) are modified sebaceous glands associated with the tarsus (collagenous structural component) of the upper and lower eyelids.
- Trial name
- NCT02735681
- Testing
- meibomian gland probing, Left eye Meibomian Gland Probing Control Group
- Where
- United States
- Sponsor
- University of Arkansas