Clinical trials: MIGS
Open Angle Glaucoma, Intraocular Pressure
An Extension Trial for Patients With Open-Angle Glaucoma Who Participated in the DF6-CL-20-01 Protocol.
The purpose of this study is to evaluate long term safety and effectiveness of the STREAMLINE® SURGICAL SYSTEM
- Trial name
- NCT06230393
- Testing
- STREAMLINE® SURGICAL SYSTEM
- Where
- Costa Rica
- Volunteers
- 17 people
- Sponsor
- New World Medical, Inc.
Open Angle Glaucoma
MIMS® Retrospective Chart Review
This is a post-market clinical follow-up, retrospective chart review of MIMS® surgical procedures conducted during time period between Sep 2023 and April 2025.
- Trial name
- NCT06614218
- Testing
- Minimally Invasive Micro Sclerostomy
- Where
- Armenia
- Volunteers
- 34 people
- Sponsor
- Sanoculis Ltd
Open Angle Glaucoma
Inferonasal MIMS® Procedure: Long-Term Follow-Up Extension Study
A long-term (24 and 30 months) follow-up extension, prospective, non-interventional, open label study for data collection from subjects who underwent prior MIMS® inferonasal surgery, in continuation of the previous clinical…
- Trial name
- NCT06577857
- Testing
- Inferonasal Minimally Invasive Micro Sclerostomy
- Where
- Armenia
- Volunteers
- 44 people
- Sponsor
- Sanoculis Ltd
POAG, MIGS
Efficacy and Safety of iStent Inject and Inject W in the Management of Primary Open-angle Glaucoma
Primary open-angle glaucoma (POAG) is a chronic eye disease in which the only validated treatment is to lower intraocular pressure (IOP). It is the 2nd leading cause of blindness worldwide.
- Trial name
- EII (NCT05062668)
- Testing
- cataract operation and istent, cataract operation only
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Glaucoma
QoL Assessment in Traditional Glaucoma Surgery and MIGS.
Quality of Life assessment before and after various glaucoma surgery (traditional and microinvasive (MIGS)).
- Trial name
- NCT03613233
- Testing
- Glaucoma surgery
- Where
- Poland
- Volunteers
- 400 people
- Sponsor
- Military Institute od Medicine National Research Institute
Open Angle Glaucoma, Ocular Hypertension
MINIject Global Long-Term Follow-up Study
The study will assess the long-term (up to 5 years) safety and performance in patients with open-angle glaucoma uncontrolled by topical hypotensive medications who had previously been implanted with a MINIject glaucoma implant.
- Trial name
- STAR-GLOBAL (NCT04524416)
- Testing
- Minimally invasive glaucoma surgery (MIGS)
- Where
- 9 sites in Colombia, France and 4 more
- Volunteers
- 116 people
- Sponsor
- iSTAR Medical
Open Angle Glaucoma
Combined Phacoemulsification With iStent Inject W Versus Hydrus for Mild to Moderate Open Angle Glaucoma
The goal of the study is to prospectively evaluate and compare Hydrus microstent to the iStent Inject Wide in combination with cataract surgery in patients with mild to moderate open angle glaucoma.
- Trial name
- NCT05583591
- Testing
- Combined cataract surgery with Hydrus microstent, Combined cataract surgery with iStent Inject W
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Diablo Eye Associates
Cataract Surgery, Glaucoma Surgery
PREFERENTIAL Study
To determine patient preference for the dexamethasone insert or topical prednisolone therapy through at Day 45 as measured by - Modified COMTOL survey.
- Trial name
- NCT04563559
- Testing
- Dextenza 0.4Mg Ophthalmic Insert, Prednisolone Acetate 1% Ophthalmic Suspension [PRED FORTE]
- Sponsor
- Duke University
Glaucoma, Cataract
Evaluation of Microinvasive Glaucoma Surgery: MINIject® Versus Hydrus® Microstent in Combination With Cataract Surgery
The study aims to investigate postoperative outcomes after two different MIGS implants (MINIject or Hydrus) in combination with cataract surgery for patients with glaucoma.
- Trial name
- MINHY (NCT06844292)
- Testing
- MINIject with Cataract Surgery, Hydrus Microstent with Cataract Surgery
- Where
- Austria
- Volunteers
- 152 people
- Sponsor
- Medical University of Graz
Glaucoma, Open-Angle, Glaucoma Eye
MINIject in Patients With Open Angle Glaucoma Using Single Operator Delivery Tool
Study to assess safety and performance of MINIject SO627 in patients with open angle glaucoma.
- Trial name
- NCT03996200
- Testing
- MINIject CS627 implant
- Where
- 3 sites in Colombia, India and 1 more
- Volunteers
- 25 people
- Sponsor
- iSTAR Medical
Primary Open Angle Glaucoma, Cataract
Safety and Efficacy of Three Variants of Canaloplasty With Phacoemulsification to Treat Glaucoma and Cataract
It is a comparative study of Safety and Efficacy of Three Variants of Canaloplasty: ab-externo, ab-interno and minicanaloplasty. Combined With Phacoemulsification to Treat Glaucoma and Cataract.
- Trial name
- NCT02908633
- Testing
- canaloplasty and phacoemulsification
- Where
- Poland
- Volunteers
- 90 people
- Sponsor
- Military Institute od Medicine National Research Institute
Glaucoma, Open Angle, MIGS
Three Year Outcomes of Combined Hydrus Microstent With iTrack Canaloplasty
The goal of this study is to learn if combining minimally invasive glaucoma surgery (MIGS) procedures with different mechanisms of action increases the effectiveness of MIGS.
- Conditions
- Glaucoma, Open Angle, MIGS, Minimally Invasive Glaucoma Surgery, Canaloplasty
- Trial name
- NCT07073937
- Testing
- Retrospective chart review
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Utah
Open Angle Glaucoma
STREAMLINE®SURGICAL SYSTEM Compared to iStent Inject W® in Patients With Open-Angle Glaucoma
A study of the Streamline Surgical System versus competitor
- Trial name
- VENICE (NCT05280366)
- Testing
- Streamline Surgical System, iStent Inject W
- Where
- 20 sites in United States, Costa Rica and 1 more
- Volunteers
- 150 people
- Sponsor
- New World Medical, Inc.
Glaucoma, Glaucoma, Open-Angle
Long Term Outcome of Combined Phacoemulsification and Excisional Goniotomy With the Kahook Dual Blade
Purpose: Characterize changes in intraocular pressure (IOP), IOP-lowering medications, and visual acuity (VA) through 3 years in patients undergoing combined phacoemulsification and excisional goniotomy with the Kahook Dual Blade…
- Conditions
- Glaucoma, Glaucoma, Open-Angle, Cataract, Angle Closure Glaucoma
- Trial name
- NCT04476810
- Testing
- kahook dual blade
- Where
- Saudi Arabia
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Ahmed Al Habash
Glaucoma, Ocular Hypertension
Comparing Refractive and Visual Outcomes of MIGS and Traditional Surgeries
The primary goal of this study is to evaluate refractive and visual outcomes in glaucoma patients who will be having either traditional glaucoma surgery or minimally invasive glaucoma surgery, also known as MIGS.
- Trial name
- NCT03584958
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Wills Eye
Primary Open-angle Glaucoma, Cataract
MINIject Implantation Combined With Cataract Surgery in Patients With POAG and Cataract
The study will assess safety and performance of MINIject implant in patients with open-angle glaucoma uncontrolled by topical hypotensive medications in conjunction with cataract surgery.
- Trial name
- STAR-VI (NCT05432245)
- Testing
- Phacoemulsification combined with minimally invasive glaucoma surgery (MIGS)
- Where
- 4 sites in Panama, Spain and 1 more
- Volunteers
- 30 people
- Sponsor
- iSTAR Medical
Postoperative Care, MIGS
Postoperative Restrictions for Patients Undergoing Minimally Invasive Gynecologic Procedures
The goal of this randomized controlled trial is to assess recovery in patients undergoing benign laparoscopic gynecologic surgery.
- Trial name
- NCT06909058
- Testing
- Study Postoperative Care
- Where
- United States
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Anna Frappaolo
Open Angle Glaucoma, Primary Open Angle Glaucoma
IOP and Medication Reduction in MIGS Procedures
The primary objective of this research is to compare the efficacy of trabecular minimally invasive glaucoma surgery (MIGS) devices (iStent vs iStent Inject vs Hydrus) for intra ocular pressure (IOP) and anti-glaucoma medication…
- Conditions
- Open Angle Glaucoma, Primary Open Angle Glaucoma, Pigmentary Glaucoma, Pseudoexfoliation Glaucoma in Both Eyes
- Trial name
- NCT04202510
- Testing
- Glaucoma and Cataract Surgery
- Where
- United States
- Sponsor
- Wills Eye
Glaucoma, Cataract
Prospective Study on DEXTENZA® Safety And Efficacy Following Concomitant MIGS and Cataract Surgery
In this study, the investigators are comparing dexamethasone ophthalmic insert (DEXTENZA®) to the current standard of care, prednisolone acetate 1% eye drops, in a glaucoma population receiving both cataract and…
- Trial name
- SUSTAIN (NCT04200651)
- Testing
- Dexamethasone Ophthalmic Insert, Prednisolone Acetate 1% Oph Susp
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- The New York Eye Surgery Center
Work-related Injury, Physical Injury
Intraoperative Exercises & Musculoskeletal Pain in Gynecologic Surgeons
The goal of this study is to evaluate the effect of intraoperative microbreaks and exercises on gynecologic surgeon body discomfort by conducting a randomized trial.
- Trial name
- GynIEx (NCT05761288)
- Testing
- Intraoperative microbreaks and exercises
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin