Clinical trials: MRI Imaging
Bipolar Disorder
The Treatment of Children and Adolescents With Treatment-Resistant Depression
This study seeks to learn about brain function in adolescents with depression and to determine whether adding lithium carbonate to antidepressant medication can reduce depression in children and adolescents.
- Trial name
- NCT00029640
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- National Institute of Mental Health (NIMH)
Prostate Cancer
ZD4054 With Positron Emission Tomography/Magnetic Resonance Imaging (PET/MRI) for Prostate Cancer
The purpose of this research study is to assess the effects of ZD4054 on prostate cancer that has spread to the bones by using new imaging techniques.
- Trial name
- NCT01119118
- Testing
- ZD4054
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- University of Wisconsin, Madison
Acute Stroke, Hyperglycemia
SELESTIAL: Trial of Insulin to Control Blood Sugar After Acute Stroke Using Magnetic Resonance Imaging (MRI) End-Points
High blood sugar (hyperglycaemia) affects 40% of acute stroke patients and has a major adverse effect on survival and recovery. Increased production of lactic acid in brain tissue that has a poor blood supply is postulated to be…
- Trial name
- NCT00124826
- Testing
- Insulin
- Where
- United Kingdom
- Volunteers
- 45 people
- Sponsor
- University of Glasgow
Healthy Volunteers, Musculoskeletal Complication
Use of Specially Designed Pediatric MR Coils on Clinical Scanners
The purpose of this research study is to test the use of new Magnetic Resonance Imaging (MRI) coils. An MRI takes pictures of body parts using a large magnet and a computer.
- Trial name
- NCT01795989
- Testing
- 1.5T MRI Elbow Coil
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Healthy Adults
Myocardial Blood Volume Measurement by Real-Time Myocardial Perfusion Echocardiography Correlates to Myocardial Compressibility by Cardiac Magnetic Resonance Imaging in Healthy Subjects
This study is being done to find out the normal amount of blood within the heart muscle and the variations in this blood flow between a cardiac MRI and TTE.
- Trial name
- NCT04724304
- Testing
- Real-Time Myocardial Echocardiography (RTMPE), Magnetic resonance image (MRI)
- Where
- United States
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Central Nervous System Diseases
Efficacy and Safety Study to Evaluate Gadavist (Gadobutrol) as Contrast Agent in Magnetic Resonance Imaging (MRI) of Brain or Spine Diseases in Chinese Patients
The purpose of this study is to determine if the contrast agent is effective and safe in the Magnetic Resonance Imaging (MRI) of brain or spine diseases in patients of Chinese origin.
- Trial name
- NCT00395460
- Testing
- Gadobutrol (Gadavist, Gadovist, BAY86-4875), Magnevist
- Where
- 4 sites in China
- Volunteers
- 147 people
- Sponsor
- Bayer
Coronary Artery Disease
Magnetic Resonance Imaging (MRI) Viability: Comparison of Myocardial Viability by Positron Emission Tomography and MRI
The purpose of this study is to compare cardiac MRI with positron emission tomography (PET) with fluorodeoxyglucose (FDG) to determine if cardiac MRI images are as good as, or better, than PET with FDG.
- Trial name
- NCT00166179
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- Emory University
Cerebral Palsy
ePrime: Evaluation of Magnetic Resonance (MR) Imaging to Predict Neurodevelopmental Impairment in Preterm Infants
Preterm infants face an uncertain future because premature birth often leads to problems with brain development and can cause cerebral palsy.
- Trial name
- ePrime (NCT01049594)
- Where
- 13 sites in United Kingdom
- Volunteers
- 625 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Complex Atypical Hyperplasia, Endometrial Cancer
18-fluorofuranylnorprogesterone (FFNP) PET/MRI as a Potential Biomarker of Response to Progesterone Therapy
Purpose: The purpose of this study is to evaluate FFNP PET/MRI's utility for predicting response to Levonorgestrel-releasing Intrauterine Device (LR-IUD) hormonal therapy for Complex Atypical hyperplasia (CAH) and Endometrial…
- Trial name
- NCT05483023
- Testing
- 18F-fluorofuranylnorprogesterone PET / MRI
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Multiple Sclerosis, Neuromyelitis Optica Spectrum Disorders
Multimodel Magnetic Resonance Imaging (MRI)of Multiple Sclerosis and Neuromyelitis Optica Spectrum Disorders
To investigate multimodel MRI exploring the pathophysiology of multiple sclerosis and neuromyelitis optica spectrum disorders. The investigators use multimodel MRI to evaluate the extent of blood-brain barrier and white matter…
- Trial name
- NCT02836327
- Testing
- Magnetic Resonance Imaging
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Chinese PLA General Hospital
Multiple Sclerosis, Magnetic Resonance Imaging
Risk Factors in Early Multiple Sclerosis
The central hypothesis of this protocol is that it is possible, using First Degree Relatives (FDRs) of patients with Multiple Sclerosis (MS) and assessing a variety of both known and unknown risk factors for MS, to define a risk…
- Conditions
- Multiple Sclerosis, Magnetic Resonance Imaging, Biomarkers, Clinically Isolated Syndrome
- Trial name
- RISEMS (NCT03586986)
- Testing
- Brain MRI
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- University of Colorado, Denver
Prostatic Neoplasms
Functional MR-guided Stereotactic Body Radiation Therapy of Prostate Cancer
To improve radiation therapy of prostate cancer, the investigators must be able to accurately identify the tumour. By using advanced functional imaging techniques available on state-of-the-art MRI scanners to clearly show the…
- Trial name
- NCT01976962
- Testing
- Stereotactic body RT with MR-guided boost
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- CancerCare Manitoba
Lumbar Radiculopathy, Magnetic Resonance Imaging
Diffusion Tensor (DTI) for the Assessement of Therapeutic Evolution of Patients With Acute Lumbar Radiculalgia
Diffusion tensor imaging (DTI) is a non-invasive MRI technique offering a functional approach that provides morphological information about the microstructures of the nerve roots.
- Conditions
- Lumbar Radiculopathy, Magnetic Resonance Imaging, Diffusion Tensor Imaging
- Trial name
- DiTi-Aïe (NCT04507113)
- Testing
- DTI sequence acquisition
- Where
- France
- Volunteers
- 150 people
- Sponsor
- Lille Catholic University
MRI
Aortic Dissection With 4-dimensional Phase-contrast Magnetic Resonance Imaging
We prospectively collected information on consecutive patients who had been evaluated using 4D PC-MRI for aortic pathology in a tertiary hospital between April 2018 and Feb 2020.
- Trial name
- NCT04481542
- Testing
- MRI
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- Chang Gung Memorial Hospital
Relapsing Remitting Multiple Sclerosis, Secondary Progressive Multiple Sclerosis
Non-inferiority Study of Ocrelizumab and Rituximab in Active Multiple Sclerosis
The DanNORMS study is a phase 3, non-inferiority clinical trial examining whether treatment of active multiple sclerosis with rituximab is non-inferior to ocrelizumab regarding efficacy and safety.
- Conditions
- Relapsing Remitting Multiple Sclerosis, Secondary Progressive Multiple Sclerosis, Primary Progressive Multiple Sclerosis
- Trial name
- DanNORMS (NCT04688788)
- Testing
- Rituximab, Ocrelizumab, Fexofenadine
- Where
- 11 sites in Denmark
- Volunteers
- 600 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Ulcerative Colitis, Irritable Bowel Syndrome
Cerebral Resonance Magnetic Imaging During Rectal Distention
Irritable bowel syndrome is responsible for chronic abdominal pain, diarrhea and/or constipation. It is a very frequent problem. However, the exact cause of irritable bowel syndrome remains unknown.
- Trial name
- NCT00213330
- Testing
- rectal distension
- Where
- France
- Volunteers
- healthy volunteers welcome
- Sponsor
- University Hospital, Rouen
Rectal Diseases, Rectal Neoplasms
Functional MRI of Hypoxia-mediated Rectal Cancer Aggressiveness
The purpose of this study is to establish a reliable method for detection of rectal cancer patients with aggressive tumor at risk of metastatic disease and death by functional MRI.
- Conditions
- Rectal Diseases, Rectal Neoplasms, Gastrointestinal Diseases, Gastrointestinal Neoplasms
- Trial name
- OxyTarget (NCT01816607)
- Testing
- new functional magnetic resonance imaging (MRI) protocols
- Where
- Norway
- Volunteers
- 192 people
- Sponsor
- University Hospital, Akershus
Cerebral Palsy, Lower Urinary Tract Symptoms
Incontinence and MRI Results in Children with Cerebral Palsy
More than 50 % of children and adults with cerebral palsy experience lower urinary tract symptoms (LUTS). This can negatively influence quality of life of the child and the total social environment.
- Trial name
- NCT05060211
- Testing
- Vancouver symptom score for dysfunctional elimination syndroms, Magnetic resonance imaging
- Where
- Belgium
- Volunteers
- 125 people
- Sponsor
- University Hospital, Ghent
Healthy Volunteer
A Study to Assess the Electrophysiology, Safety, Tolerability, Pharmacokinetics and Pharmacodynamics Response Using Magnetic Resonance Imaging of SAGE-718 Using a Ketamine Challenge in Healthy Subjects
This study is a phase 1, double-blind, placebo-controlled crossover study of SAGE-718 using a ketamine challenge, to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamic response using magnetic resonance…
- Trial name
- NCT03770780
- Testing
- SAGE-718
- Where
- 2 sites in United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Supernus Pharmaceuticals, Inc.
Gliomas, Malignant, Metastases to Brain
Intraoperative Sonographically Versus Fluorescence-guided Resection of Contrast-enhancing Gliomas and Brain Metastases
Objective of the study is to determine whether intraoperative ultrasound guided resection of gliomas with contrast enhancement in magnetic resonance imaging and brain metastases can achieve as high rate of gross total resection…
- Trial name
- SONOFLUO (NCT05475522)
- Testing
- Ultrasound guided brain tumor resection, 5-aminolevulinic acid fluorescence-guided brain tumor resection
- Where
- Russia
- Volunteers
- 134 people
- Sponsor
- Sklifosovsky Institute of Emergency Care