Clinical trials: MYOPATHY
Duchenne Muscular Dystrophy (DMD)
Evaluation of the Safety, Tolerability, and Efficacy of LE051 in Patients With Duchenne Muscular Dystrophy
The purpose of this study is to evaluate the safety, tolerability, and efficacy of LE051 intravenous therapy in DMD patients treated with exon 51 skipping therapy.
- Trial name
- NCT06900049
- Testing
- LE051
- Where
- China
- Volunteers
- 12 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Tennis Elbow
Ozone Therapy in Lateral Epicondylopathy
Lateral epicondylopathy (LE) is a common cause of elbow pain. In the literature, there are few studies evaluating the efficacy of ozone injection in LE. To our knowledge, there is no study comparing it with exercise therapy.
- Trial name
- O2-O3 (NCT07240155)
- Testing
- Ozone treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Dokuz Eylul University
Systemic Lupus Erythematosus (SLE), Systemic Sclerosis (SSc)
A Study to Assess CLBR001+SWI019 in Subjects With Autoimmune Diseases
The goal of this clinical trial is to evaluate CLBR001 and SWI019 as a treatment for patients with autoimmune disorders, including systemic lupus erythematosus, systemic sclerosis, and idiopathic inflammatory myositis.
- Conditions
- Systemic Lupus Erythematosus (SLE), Systemic Sclerosis (SSc), Idiopathic Inflammatory Myopathy (IIM)
- Trial name
- NCT06913608
- Testing
- CLBR001 + SWI019
- Sponsor
- Calibr, a division of Scripps Research
Fibromyalgia, Hormonal Responses to Exercise in Patients With Fibromyalgia.
Effects of Whole-Body Vibration Exercise on Serum IGF-1 in Fibromyalgia
The purpose of this study was to investigate the acute and chronic effect of whole-body vibration exercise on serum insulin-like growth factor-1 levels in women with fibromyalgia (FM).
- Trial name
- NCT00650715
- Testing
- Vibratory platform, PowerPlate®, Badhoevendorp, Netherlands
- Where
- Spain
- Volunteers
- 24 people
- Sponsor
- Institut Nacional d'Educacio Fisica de Catalunya
Temporal Arteritis
Aetiology of TemporaL Arteritis Study
Giant Cell Arteritis (GCA) is the most common vasculitis and has significant morbidity in terms of blindness, stroke, and tissue necrosis.
- Trial name
- ATLAS (NCT02584517)
- Sponsor
- University of Oxford
Hemiplegia
Rotator Cuff Tears in Hemiplegic Shoulder
The purpose of the study is to evaluate the prevalence of rotator cuff tears in the shoulders of hemiplegic patients of different severity.
- Trial name
- NCT00998868
- Where
- South Korea
- Volunteers
- 51 people
- Sponsor
- Seoul National University Hospital
Rhabdomyolysis, Acute Kidney Injury
Use of a Vacuum Mattress During Laparoscopic Sleeve Gastrectomy to Reduce the Concentration of Rhabdomyolysis Markers and Acute Renal Failure
This prospective clinical trial aimed to assess the usefulness of the usage of a vacuum mattress during laparoscopic sleeve gastrectomy (LSG) in the reduction of levels of rhabdomyolysis markers (myoglobin, creatine kinase…
- Conditions
- Rhabdomyolysis, Acute Kidney Injury, Bariatric Surgery Candidate
- Trial name
- NCT06338423
- Testing
- vacuum mattress, Standard Mattress
- Where
- Poland
- Volunteers
- 1,184 people, healthy volunteers welcome
- Sponsor
- Jagiellonian University
Lateral Epicondylitis
Active Release Technique and Graston Technique in Patients With Lateral Epicondylitis
This study will be a randomized control trial and will be conducted in Pakistan Railway Hospital Rawalpindi. A sample of 36 participants will be taken. Patients will be divided into two groups by sealed envelop method.
- Trial name
- NCT05070559
- Testing
- Active Release Technique, Graston Technique Group
- Where
- Pakistan
- Volunteers
- 36 people
- Sponsor
- Riphah International University
Bruxism, Self-management
Impact of Self-Management Strategies in Self-Reported Bruxism
This study aim to evaluate the effects of a 6-week self-management program on pain, muscle stiffness, and temporomandibular joint (TMJ) functions in sedentary individuals aged 18-40 with bruxism.
- Conditions
- Bruxism, Self-management, Pain, Proprioception
- Trial name
- NCT06914388
- Testing
- Self-Management Strategies
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Cyprus International University
Cerebral Palsy, Spasticity, Muscle
Shock Wave Therapy for Management of Spasticity in Patients With Cerebral Palsy
Spasticity is the most common motor disorder in cerebral palsy (CP). The objectives of his therapeutic approach include; reducing pain, ease of use of orthopedic aids, improving posture, minimizing contractures and deformity, and…
- Conditions
- Cerebral Palsy, Spasticity, Muscle, Extracorporeal Shock Wave Therapy
- Trial name
- NCT05702606
- Testing
- Radial extracorporeal shock wave therapy (rESWT)
- Where
- Spain
- Volunteers
- 73 people
- Sponsor
- Fundacio Aspace Catalunya
Lateral Epicondylitis, Patient Engagement
Comparison of PELOID Therapy and Kinesio Tape Effectiveness in Patients With Lateral Epicondylitis
In this study, the difference in effectiveness between PELOID therapy and kinesio tape in the treatment of lateral epicondylitis; It was planned to evaluate the effects of these treatments on pain, functionality, activities of…
- Trial name
- NCT04687943
- Testing
- PELOID therapy, kinesio tape, exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 3 people
- Sponsor
- Konya Meram State Hospital
Fibromyalgia
Occipital Nerve Stimulation in Fibromyalgia
The aim of this study is to investigate whether greater occipital nerve stimulation is effective in the treatment of fibromyalgia related pain.
- Trial name
- NCT00917176
- Testing
- Occipital nerve stimulation
- Where
- Belgium
- Sponsor
- University Hospital, Antwerp
Dupuytren Disease
Percutaneous Aponeurotomy in the Treatment of Dupuytren's Disease
The efficiency of percutaneous aponeurotomy in the treatment of Dupuytrens disease is well known. However, the duration of the clinical improvement after aponeurotomy is not well known.
- Trial name
- APADUP (NCT02474576)
- Testing
- Percutaneous aponeurotomy
- Where
- France
- Volunteers
- 130 people
- Sponsor
- Groupe Hospitalier Diaconesses Croix Saint-Simon
Pain, Fibromyalgia
Real-time Pain Monitoring in Fibromyalgia Patients
This study aims to examine whether the pain of fibromyalgia patients can be reduced with utilization of real-time pain monitoring system (PAAS).
- Trial name
- NCT03571009
- Testing
- utilization of PAAS
- Volunteers
- 25 people
- Sponsor
- Ji Hyeon Ju
Amyotrophic Lateral Sclerosis, Muscular Dystrophy
Innovative Ultrasound Technology in Neuromuscular Disease
This study is utilizing ultrasound measurement to measure neuromuscular disease status in adult patients. The hypothesis is the by quantifying ultrasound data, it is possible that ultrasound can be utilized as a tool to determine…
- Conditions
- Amyotrophic Lateral Sclerosis, Muscular Dystrophy, Radiculopathy, Myopathy
- Trial name
- AQUIRe (NCT02104921)
- Where
- United States
- Volunteers
- 223 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Acute Kidney Injury, Critical Illness Myopathy
Critical Illness Myopathy and Trajectory of Recovery in AKI Requiring CRRT
The purpose of this study is to determine whether patients with acute kidney injury requiring renal replacement therapy have a higher incidence of muscle wasting than controls and whether the course of recovery is longer compared…
- Conditions
- Acute Kidney Injury, Critical Illness Myopathy, Dialysis; Complications
- Trial name
- NCT05287204
- Testing
- Musculoskeletal ultrasound, Assessments of muscle strength and physical function, Metabolomics
- Where
- 3 sites in United States
- Volunteers
- 10 people
- Sponsor
- University of Iowa
Trigeminal Neuralgia, Temporomandibular Disorder
Comorbid Painful TMD Among Trigeminal Neuralgia
An observational study following up with trigeminal neuralgia patients to understand their comorbid facial pain condition, specifically temporomandibular disorder.
- Conditions
- Trigeminal Neuralgia, Temporomandibular Disorder, Myofascial Pain, Trigeminal Neuropathy
- Trial name
- TNTMD (NCT05914558)
- Testing
- Clinical appointment
- Where
- 2 sites in United States
- Sponsor
- University of Minnesota
Cholecystitis; Gallstone, Mechanical Ventilation Pressure High
The Effect of Ventilation Modes on Cerebral Oxymetry In Operation
In laparoscopic cholecystectomy method, Insufflation of CO2 in abdominal cavity causes positioning of the diaphragm upwards, a decrease in lung's volume and its compliance, an increase in the airway resistance, mismatch between…
- Conditions
- Cholecystitis; Gallstone, Mechanical Ventilation Pressure High, Intraabdominal Hypertension
- Trial name
- NCT04723043
- Testing
- mechanical ventilation modes
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Cerebrovascular Accident
A Multicenter, Double-Blind, Randomized, Placebo-Controlled Study to Evaluate the Efficacy and Safety of GSK1358820 (Botulinum Toxin Type A) in Chinese Subjects With Post-stroke Upper Limb Spasticity
This trial is a multicenter, double-blind, randomized, placebo-controlled study to compare GSK1358820 (Botulinum Toxin Type A, also known as "OnabotulinumtoxinA" or "Botox") with placebo on the efficacy and safety of treatment in…
- Trial name
- NCT01153815
- Testing
- GSK1358820(Botulinum toxin type A)
- Where
- 13 sites in China
- Volunteers
- 170 people
- Sponsor
- GlaxoSmithKline
Fibromyalgia, Chronic Fatigue Syndrome
Treatment of CFS & Fibromyalgia With Recovery Factors
The study will explore if Recovery Factors improve symptoms in fibromyalgia and chronic fatigue syndrome
- Trial name
- NCT04381793
- Testing
- Recovery Factors
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- Practitioners Alliance Network
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