Clinical trials: MYOPATHY
Pain, Chronic, Fatigue Syndrome, Chronic
Activate For Life: mHealth Intervention To Address Pain And Fatigue In Low-income Older Adults Aging In Place
The Overall Aim of the present proposal is to evaluate the feasibility of an integrated mind-body intervention, Activate for Life, to improve overall physical activity and mental health and reduce pain and fatigue, resulting in…
- Conditions
- Pain, Chronic, Fatigue Syndrome, Chronic, Aging
- Trial name
- Activate (NCT03853148)
- Testing
- Otago, Gentle yogic breathing, Behavioral Activation
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Depression, Depressive Disorder
Study Evaluating Desvenlafaxine Succinate Sustained Release (DVS SR) Versus Placebo in Peri- and Postmenopausal Women
Desvenlafaxine succinate (DVS) is a potent and selective serotonin and norepinephrine reuptake inhibitor (SNRI). The sustained-release (SR) formulation, DVS SR, is being studied in the development program for the treatment of…
- Conditions
- Depression, Depressive Disorder, Depressive Disorder, Major
- Trial name
- NCT00369343
- Testing
- Desvenlafaxine administered as a succinate salt in a sustained-release form (DVS SR)
- Where
- 37 sites in United States
- Volunteers
- 381 people
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Lateral Epicondylitis (Tennis Elbow)
The Effect of Adding Deep Friction Massage to Eccentric Training Exercises in Lateral Epicondylitis
Background: Lateral epicondylitis (LE) often benefits from eccentric training exercises, but combining them with deep friction massage (DFM) might enhance outcomes.
- Trial name
- NCT06597643
- Testing
- Eccentric Training, Deep Friction Massage
- Volunteers
- 46 people
- Sponsor
- Cairo University
Fibromyalgia, Pain
"Using a Multisite TENS SysteM to Improve Fibromyalgia-related Symptoms.
Fibromyalgia is a debilitating pain condition that is characterized by the chronic occurrence of pain affecting the musculoskeletal system, a sensitivity to pressure stimuli, and a low threshold to noxious stimuli.
- Trial name
- EXOFIB3 (NCT06702176)
- Testing
- EXOPULSE MOLLII SUIT active
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Institut De La Colonne Vertebrale Et Des Neurosciences
Temporomandibular Disorders (TMD), Manual Therapy
Effectiveness of the Fascial Distortion Model in Temporomandibular Disorders: A Randomized Sham-controlled Trial
The aim of the study was to investigate the effectiveness of Manual Therapy Based on the Fascial Distortion Model in individuals with temporomandibular disorders compared to sham control.
- Conditions
- Temporomandibular Disorders (TMD), Manual Therapy, Fascial Distortion
- Trial name
- NCT06627855
- Testing
- Fascial Distortion Model
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Karabuk University
Temporomandibular Joint Dysfunction
The Effects of Trigger Point Treatment in Temporomandibular Joint Dysfunction
The aim of this study to investigate the effectiveness of trigger point treatments (ischemic compression) on pain intensity, chronic pain severity, range of motion(ROM), pain pressure threshold (PPT) and functionality on patient…
- Trial name
- NCT04122352
- Testing
- Ischemic compression, Exercises (Rocabodo's 6x6 exercises and posture exercises)
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Istanbul University - Cerrahpasa
Widspread Chronic Pain, Fibromyalgia
The Effect of Vagus Nerve Stimulation on Pain and Functional Activities in Individuals With Chronic Widespread Pain
The goal of this clinical trial is to examine the effect of vagus nerve stimulation (VNS) on chronic, widespread pain in adults.
- Trial name
- NCT07080749
- Testing
- Vagal nerve stimulation through deep exhalation exercise, Vagal nerve stimulation through ear electrical stimulation, No intervention (observational study)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of North Georgia
Fibromyalgia
Lifestyle Physical Activity to Reduce Pain and Fatigue in Adults With Fibromyalgia
The purpose of this study is to determine the effect of 3 months of daily, 30-minute lifestyle physical activity on pain and fatigue in inactive adults with fibromyalgia (FM).
- Trial name
- NCT00383084
- Testing
- Lifestyle physical activity (LPA), Fibromyalgia education
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- Johns Hopkins University
Tennis Elbow
Eccentric Exercise or Radiofrequent Microtenotomy as Treatment of Lateral Epicondylalgia
The aim is to study the effects related to function and pain during eccentric exercise and surgery with radiofrequency microtenotomy as post-surgical rehabilitation, compared with only eccentric exercise, in patients with lateral…
- Trial name
- NCT02304952
- Testing
- Radiofrequency microtenotomy, Eccentric exercise, Arthrocare Topaz MicroDebrider
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- St Goran's Hospital
Fibromyalgia
UHCDS a-tDCS Combined With Therapeutic Exercise in Fibromyalgia Patients
The purpose of this study is to assess the effects on fatigue and sleep of Unihemispheric Concurrent Dual-Site anodal Transcranial Direct Current Stimulation combined with therapeutic exercise in Fibromyalgia patients.
- Trial name
- NCT05726149
- Testing
- Real UHCDS a-tDCS, Therapeutic exercise
- Where
- Spain
- Volunteers
- 90 people
- Sponsor
- University of Castilla-La Mancha
Chronic Pain, Pain, Chronic
An Evaluation of a Public Health Campaign Related to Persistent Pain in the United Kingdom
The goals of this study are To define what the public perceptions of persistent pain using a national survey Explore relationships between the reported pubic beliefs and demographic factors collected.
- Conditions
- Chronic Pain, Pain, Chronic, Pain, Back, Musculoskeletal Pain
- Trial name
- NCT06151678
- Testing
- Pain Education
- Where
- United Kingdom
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Teesside University
Bandages, Muscle Soreness
Kinesio Taping in Muscle Damage Response Induced by Eccentric Exercise
Sixty volunteers with a mean age of 21,8 ± 2,6 years participated in this study, randomly distributed into one of the following groups: control, Kinesio taping group with tension in the anterior arm region and Kinesio taping…
- Trial name
- NCT02945098
- Testing
- Kinesio Taping
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Rio Grande do Norte
Pain, Head, Pain Syndrome
Botulinum Toxin Versus Placebo Injections to Temporalis and Masseter Muscles
This study aims to determine whether the injection of botulinum toxin A or placebo (unpreserved 0.9% sodium chloride) into the masseter and temporalis muscles provides pain relief and improved jaw function in those who suffer…
- Conditions
- Pain, Head, Pain Syndrome, Temporomandibular Disorder, Myofascial Pain Syndrome
- Trial name
- NCT03223298
- Testing
- Botulinum toxin type A, 0.9% Sodium Chloride Injection
- Where
- 2 sites in United States
- Volunteers
- 75 people
- Sponsor
- Weill Medical College of Cornell University
Multiple Sclerosis, Spasticity
A Long-term Safety Extension Study of Delta-9-tetrahydrocannabinol (THC) and Cannabidiol (CBD) in Multiple Sclerosis
An extension study to evaluate the long-term safety, tolerability and efficacy of GW-1000-02 treatment in multiple sclerosis.
- Trial name
- NCT01610687
- Testing
- GW-1000-02
- Where
- United Kingdom
- Volunteers
- 137 people
- Sponsor
- Jazz Pharmaceuticals
Muscular Dystrophies, Scapular Dyskinesis
Evaluation of a Textile Scapula Orthosis
Shoulder instability due to muscle weakness is a common problem in disorders of the upper extremities. During arm motion, the scapula acts as a dynamic base for the humeral head.
- Conditions
- Muscular Dystrophies, Scapular Dyskinesis, Muscular Dystrophy, Facioscapulohumeral, Muscle Weakness
- Trial name
- ScapOrthosis (NCT04154098)
- Testing
- Scapula orthosis assistance, Manual scapula assistance, No assistance
- Where
- 2 sites in Germany, Switzerland
- Volunteers
- 8 people
- Sponsor
- Swiss Federal Institute of Technology
Fibromyalgia
Community-based Intervention for Fibromyalgia: A Pilot Trial
Fibromyalgia (FM) is a multi-factorial chronic pain condition characterized by fluctuating and heterogeneous symptoms. This leads to both reduced patient function and quality of life and consequentially, significant economic…
- Trial name
- NCT03270449
- Testing
- Multidisciplinary intervention
- Where
- Canada
- Volunteers
- 84 people
- Sponsor
- University of British Columbia
Duchene Muscular Dystrophy, Becker Muscular Dystrophy
Multiparametric Ultrafast Ultrasound Biomarkers for Duchenne and Becker Muscular Dystrophies
The purpose of this research study is to determine the potential of a multiparametric ultrasound approach to non-invasively monitor disease progression and to serve as an objective outcome measure for future clinical trials in…
- Trial name
- INNOVAN (NCT07378553)
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Nantes University Hospital
Intensive Care (ICU) Myopathy, Functional Independence
Correlation Between Spirometry and Functional Independence in Adult Post-ICU Patients
Several complications and comorbidities are frequently found in patients admitted to an Intensive Care Unit (ICU), including acquired ICU muscle weakness and physical and cognitive limitations.
- Trial name
- NCT03619915
- Testing
- Spirometry, Functional Independence Measure
- Volunteers
- 197 people
- Sponsor
- Universidade Estadual do Oeste do Paraná
Polymyositis, Dermatomyositis
Allogeneic Mitochondria (PN-101) Transplantation for Refractory Polymyositis or Dermatomyositis
To determine the maximum tolerated dose (MTD) based on the safety and tolerability after single-dose administration of PN-101 in patients with refractory polymyositis or dermatomyositis.
- Trial name
- NCT04976140
- Testing
- PN-101
- Where
- 3 sites in South Korea
- Volunteers
- 9 people
- Sponsor
- Paean Biotechnology Inc.
Chronic Pain
Home-based Transcranial Stimulation in the Treatment of Patients With Refractory Chronic Pain
Refractory chronic pain represents a serious and limiting health condition which does not respond to standard pharmacological therapy.
- Trial name
- NCT05099406
- Testing
- Transcranial electrical stimulation
- Where
- Spain
- Volunteers
- 120 people
- Sponsor
- University of Santiago de Compostela
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