Clinical trials: MYOPATHY
Fibromyalgia
Repetitive Transcranial Magnetic Stimulation in Fibromyalgia
The purpose of this study is to determine the analgesic effectiveness of Repetitive Transcranial Magnetic Stimulation (rTMS) used as an additional procedure to rehabilitation exercises in patient suffering from fibromyalgia.
- Trial name
- STIMALGI (NCT01308801)
- Testing
- active rTMS + rehabilitation exercise
- Where
- France
- Volunteers
- 42 people
- Sponsor
- University Hospital, Grenoble
Burns, Burn Scar
A Prospective Trial of Virtual Home Rehabilitation After Burn Injury
The overarching goal for this prospective randomized controlled trial (PRCT) is to determine whether a virtual-environment, home-rehabilitation program improves functional outcomes for individuals after a burn injury.
- Conditions
- Burns, Burn Scar, Contracture
- Trial name
- NCT03475654
- Testing
- Technology-assisted rehabilitation, Usual care
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- University of Washington
Type 2 Spinal Muscular Atrophy
Efficacy and Safety of Intrathecal OAV101 (AVXS-101) in Pediatric Patients With Type 2 Spinal Muscular Atrophy (SMA)
This was a Phase III multi-center, single dose (1.2 x 10^14 vector genomes), randomized, sham controlled, double-blind study that investigates the efficacy, safety and tolerability of OAV101B in treatment naive, sitting and never…
- Trial name
- STEER (NCT05089656)
- Testing
- OAV101
- Where
- 42 sites in United States, Brazil and 11 more
- Volunteers
- 126 people
- Sponsor
- Novartis Pharmaceuticals
Cramps, Muscle Cramp
The RELAX Trial: Nonpharmaceutical Intervention for Nocturnal Muscle Cramps
The purpose of the study is to learn about reducing the symptoms and severity of nighttime lower body muscle cramps in patients with and without cirrhosis.
- Trial name
- RELAX (NCT05457322)
- Testing
- Behavioral intervention one, Behavioral intervention two
- Where
- 6 sites in United States
- Volunteers
- 99 people
- Sponsor
- University of Michigan
Local Anesthetic Complication, Local Anesthetic Drug Adverse Reaction
Defining Normal Postoperative Magnetic Resonance Imaging After Total Knee Arthroplasty
The aim of this study was to describe the postoperative "baseline" magnetic resonance imaging (MRI) appearance of the ipsilateral thigh musculature after total knee arthroplasty (TKA).
- Trial name
- NCT04821245
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Benaroya Research Institute
Fibromyalgia, Chronic Low Back Pain
Mapping Stress and Pain Interactions (G072323N)
The over-arching goal of this observational (case-control, with a cross-sectional and longitudinal arm) study is to comprehensively map stress system (dys)function (including reactivity and recovery) in people with primary…
- Conditions
- Fibromyalgia, Chronic Low Back Pain, Subacute Low Back Pain
- Trial name
- STRAIN (NCT06892977)
- Where
- Belgium
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University Ghent
Temporomandibular Joint Internal Derangement (ADWR)
Evaluation of Intravenous Sodium Valproate on Interleukin-6 Levels in Patients With TMJ Disc Displacement
This study aims to evaluate if adding the medication Sodium Valproate to a standard jaw procedure (arthrocentesis) can help reduce inflammation and improve healing in patients with certain jaw joint problems.
- Trial name
- NCT07487675
- Testing
- sodium valproate, TMJ Arthrocentesis
- Where
- Egypt
- Volunteers
- 10 people
- Sponsor
- Tanta University
Aphthous Stomatitis, Burning Mouth Syndrome
Evaluation and Treatment of Oral Soft Tissue Diseases
This study offers evaluation and treatment of patients with diseases of the mouth or systemic diseases that involve the mouth. The protocol is not designed to test new treatments; rather, patients will receive current standard of…
- Conditions
- Aphthous Stomatitis, Burning Mouth Syndrome, Lichen Planus, Mouth Disease
- Trial name
- NCT00001601
- Testing
- Electrocardiogram, Biopsies, Diagnostic imaging
- Where
- United States
- Volunteers
- 999 people
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Fibromyalgia
A Brain Imaging Study of Tai Chi on Fibromyalgia
To accomplish our Specific Aims, we propose to conduct a two-session fMRI experiment in up to 30 patients with fibromyalgia (FM) and up to 30 healthy controls.
- Trial name
- NCT01857219
- Testing
- Tai chi
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Chronic Pain, Opioid Use
Neuroimaging of Opioid Phase (OPAL)
The purpose of this study is to compare activity in the brains of female adults with chronic pain and/or opioid use, and healthy female adults that may help to develop new and targeted treatments for adults with chronic pain and…
- Trial name
- OPAL (NCT05905419)
- Testing
- Opioid Phase
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Duke University
Temporomandibular Joint Disorders, Orofacial Pain
Computed Guided Prolotherapy Versus Conventional Prolotherapy
The aim of that study is to compare between conventional prolotherapy and computed guided prolotherapy in treatment of temporomandibular joint (TMJ) internal derangement.
- Trial name
- NCT06132594
- Testing
- Conventional arthrocentesis followed by I-PRF injection, 3d surgical guided Arthrocentesis followed by I-PRF injection
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Primary Dysmenorrhea, Premenstrual Syndrome
The Relationship of Premenstrual Syndrome and Primary Dysmenorrhea With Severity of Temporomandibular Disorders
Premenstrual pain, menstrual pain, other pains, and somatic symptoms may occur together. Therefore, this study aims to examine the severity of temporomandibular disorders in individuals complaining of premenstrual syndrome or…
- Conditions
- Primary Dysmenorrhea, Premenstrual Syndrome, Temporomandibular Disorder
- Trial name
- NCT06052722
- Testing
- Correlation assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Tokat Gaziosmanpasa University
Temporomandibular Disorder, Forward Head Posture
Forward Head Posture Correction Impact on Temporomandibular Dysfunction
The goal of this clinical trial is to test the effect of nerd neck correction on damaged jaw in people who suffers from jaw problems and nerd neck.
- Trial name
- NCT06123351
- Testing
- Denneroll cervical traction orthodontic, stretching and strengthening exercises, Vacuum-formed soft occlusal splint
- Where
- United Arab Emirates
- Volunteers
- 63 people
- Sponsor
- Shima Abdollah Mohammad Zadeh
GNE Myopathy, Hereditary Inclusion Body Myopathy (HIBM)
An Open Label Phase 2 Extension Study of Higher Dose Sialic Acid-Extended Release (SA-ER) Tablets and Sialic Acid-Immediate Release (SA-IR) Capsules in Patients With Glucosamine (UDP-N-acetyl)-2-Epimerase (GNE) Myopathy
The safety objectives of the study are to: evaluate additional long-term safety of SA-ER treatment of participants with GNE myopathy previously treated with SA-ER at dose of 6g/day (Part I); evaluate the safety of 12g /day SA…
- Trial name
- NCT01830972
- Testing
- SA-ER 500 mg, SA-IR 500 mg
- Where
- 4 sites in United States, Israel
- Volunteers
- 59 people
- Sponsor
- Ultragenyx Pharmaceutical Inc
Duchenne Muscular Dystrophy
Efficacy and Safety Study of WVE-210201 (Suvodirsen) With Open-label Extension in Ambulatory Patients With Duchenne Muscular Dystrophy
This is a Phase 2/3, multicenter, randomized, double-blind, placebo-controlled study with an open-label extension period to evaluate the safety and efficacy of WVE-210201 (suvodirsen) in ambulatory male pediatric patients with…
- Trial name
- DYSTANCE 51 (NCT03907072)
- Testing
- WVE-210201 (suvodirsen)
- Where
- 22 sites in United States, Belgium and 6 more
- Volunteers
- 6 people
- Sponsor
- Wave Life Sciences USA, Inc.
Musculoskeletal and Connective Tissue Disorders
Effects of a School-based Exercise Program on Posture, Trunk Range of Motion, and Musculoskeletal Pain
The objective of this study was to evaluate the effects of a school-based exercise program on posture, trunk range of motion and musculoskeletal pain in schoolchildren. This study was a Randomized controlled trial.
- Trial name
- NCT02255695
- Testing
- School-based exercise program
- Where
- Brazil
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Sao Carlos
Dermatomyositis, Juvenile Dermatomyositis
Efficacy and Safety of H.P. Acthar Gel for the Treatment of Refractory Cutaneous Manifestations of Dermatomyositis
This study will assess the safety and efficacy of H.P. Acthar gel for treating the cutaneous manifestations in patients with refractory classic dermatomyositis, juvenile dermatomyositis, and amyopathic dermatomyositis.
- Trial name
- NCT02245841
- Testing
- H.P. Acthar Gel
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- The Cleveland Clinic
Lateral Epicondylitis
Efficacy of One or Two Botulinum Toxin Injections in the Treatment of Chronic Lateral Epicondylalgia: a Retrospective Study (EPITOX)
Despite being a self-limiting injury, lateral epicondylitis (LE) can be difficult to manage. In cases of refractory LE, conservative treatment fails and symptoms persist over 6 months.
- Trial name
- EPITOX (NCT06765694)
- Testing
- Botulinum toxin injection
- Where
- France
- Volunteers
- 80 people
- Sponsor
- University Hospital, Brest
Fibromyalgia
Medical Cannabis for Treating Pain Related to Fibromyalgia
The goal of this interventional study is to learn about the effect of Medicinal Cannabis (Bedrocan®) on Fibromyalgia patients with pain resistant to conventional therapy.
- Trial name
- Bedrocan®-LD (NCT05939466)
- Testing
- Bedrocan®-type cannabis (22% THC, <1% CBD)
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Universita degli Studi della Basilicata
Fibromyalgia
Manual Diaphragmatic Release on Exercise Capacity and Quality of Life in Women With Fibromyalgia
Evaluate the effect of manual diaphragmatic release on exercise capacity, inspiratory muscles strength, symptoms severity, and health-related quality of life in women diagnosed with fibromyalgia.
- Trial name
- NCT07641166
- Testing
- Manual Diaphragmatic Release, Aerobic Training
- Volunteers
- 60 people
- Sponsor
- Middle East University
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