Clinical trials: MYOPATHY
Temporomandibular Joint Disorders, Temporomandibular Sprain
Intra-articular Magnesium Sulfate for Tmj Dysfunction
mixing the magnesium sulfate with dextrose for management of tmj pain will be studied using intra-articular injection of the solution
- Trial name
- NCT03675659
- Testing
- intra-articular injection
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Cairo University
Abdominal Compartment Syndrome
Abdominal Compartment Syndrome and Ruptured Aortic Aneurysm : Validation of a Predictive Test
It is an observational study on ruptured abdominal aortic aneurysm and abdominal compartment syndrome. the aim of this study is to assess the qualities of a predictive score on the occurence of this syndrome after surgery of…
- Trial name
- SCA-AAR (NCT02859662)
- Testing
- ruptured aortic aneurysm
- Where
- 10 sites in France
- Volunteers
- 165 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Central Nervous System Sensitization
Correlation Between Central Sensitization Inventory and Posturographic Data
To investigate the use of balance as a screening tool for Central Sensitization, a condition of the nervous system that is associated with the development and maintenance of chronic pain.
- Trial name
- NCT03058003
- Testing
- Posturography Evaluation, Central Sensitization Inventory
- Where
- 2 sites in United States, Australia
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Caps Research Network
Fibromyalgia, Chronic Fatigue Syndrome
Tracking Peripheral Immune Cell Infiltration of the Brain in Central Inflammatory Disorders Using [Zr-89]Oxinate-4-labeled Leukocytes.
This study will use brain Positron Emission Tomography/ Magnetic Resonance Imaging (PET/MRI) and an investigational radioactive drug called [Zr-89]oxine to track the location of white blood cells (also called leukocytes) in the…
- Conditions
- Fibromyalgia, Chronic Fatigue Syndrome, Multiple Sclerosis, Healthy
- Trial name
- NCT03807973
- Testing
- [Zr-89]Oxine-labeled leukocytes PET/MRI
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Spasticity
Imaging of 3D Innervation Zone Distribution in Spastic Muscles From High-density Surface EMG Recordings
The purpose of this study is to evaluate if it is possible to use a new 3D imaging method to guide Botulinum neurotoxin (BTX) injection for muscle spasticity management after stroke.
- Trial name
- NCT03302741
- Testing
- Botulinum neurotoxin (BTX), Physical Therapy, Standard BTX injection (ultrasound guided)
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- The University of Texas Health Science Center, Houston
Fibrodysplasia Ossificans Progressiva
A Study to Examine the Safety, Tolerability and Effects on Abnormal Bone Formation of REGN2477 in Patients With Fibrodysplasia Ossificans Progressiva
This is a three period study design consisting of a 6-month, randomized, double-blind placebo-controlled treatment (period 1) followed by a 6-month, open-label treatment (period 2) and a follow-up treatment period (period 3).
- Trial name
- LUMINA-1 (NCT03188666)
- Testing
- REGN2477
- Where
- 11 sites in United States, Canada and 6 more
- Volunteers
- 44 people
- Sponsor
- Regeneron Pharmaceuticals
Inclusion Body Myositis
Cell Therapy for IBM by Muscle Injection of ADSVF
Inclusion Body Myositis is a slowly but disabling myopathy, the most frequent in patients over 50 years old. No treatments (in particular immunosuppressive) are known to be efficient.
- Trial name
- ADSVF-in-IBM (NCT05032131)
- Testing
- ADSVF
- Where
- France
- Volunteers
- 32 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Temporomandibular Joint Disorders
Characteristics of Cytokine Response in Patients With Temporomandibular Disorders Treated With Occlusal Splint Therapy
The goal of this intervention study is to determine the effect of occlusal splint (OS) therapy on the concentration of inflammatory cytokines in serum and gingival crevicular fluid (GCF) in patients with temporomandibular…
- Trial name
- NCT06043024
- Testing
- Stabilization occlusal splint
- Where
- Croatia
- Volunteers
- 36 people
- Sponsor
- Josip Juraj Strossmayer University of Osijek
Duchenne Muscular Dystrophy
A Phase I/II Study of BMN053 in Subjects With Duchenne Muscular Dystrophy (DMD)
The purpose of the study is to see whether BMN053 is safe and effective to use as medication for Duchenne muscular dystrophy (DMD) patients with a mutation around location 53 in the DNA for the dystrophin protein.
- Trial name
- NCT01957059
- Testing
- Regimen Selection Phase Group 2, Regimen Selection Phase Group 3, Treatment Phase Group 4
- Where
- 6 sites in Belgium, France and 3 more
- Volunteers
- 9 people
- Sponsor
- BioMarin Pharmaceutical
Musculoskeletal Pain
Emotional Awareness and Expression Therapy (EAET) or Cognitive Behavior Therapy (CBT) for Older Veterans With Chronic Musculoskeletal Pain
A randomized clinical trial for Veterans age 50 years and older with chronic musculoskeletal pain in which Emotional Awareness and Expression Therapy (EAET) is compared against Cognitive Behavior Therapy (CBT) to evaluate…
- Trial name
- NCT03844880
- Testing
- Emotional Awareness and Expression Therapy, Cognitive Behavior Therapy
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- VA Greater Los Angeles Healthcare System
Chronic Pain, Temporomandibular Disorder
An Internet-based Multimodal Pain Program for Chronic Temporomandibular Disorder Pain
Background Chronic temporomandibular disorders (TMD) pain is an undertreated condition in Sweden despite the fact that national guidelines includes effective treatment options.
- Trial name
- NCT04363762
- Testing
- Internet-based multimodal pain program, Occlusal splint
- Volunteers
- 40 people
- Sponsor
- Malmö University
Fibromyalgia
Evaluate the Clinical Efficacy of Whole Body Cryotherapy in the Cryosense Cabin for the Treatment of Fibromyalgia
The aim of this study is to evaluate the effectiveness of an intervention with sessions of 3 minutes of whole body cryotherapy (WBC) in the Cryosense cabin. Measurement period time: 8 weeks.
- Trial name
- NCT03425903
- Testing
- Whole body cryotherapy sessions
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Tecnología e Innovación Médico Estética S.L.
Fibromyalgia, Interoception
The Role of Interoceptive Sensitivity in Central Sensitization Symptom Severity in Fibromyalgia
In fibromyalgia, the increased central sensitization symptom burden can lead to a disruption in the individual's interoception and difficulties in managing symptoms.
- Conditions
- Fibromyalgia, Interoception, Central Sensitization
- Trial name
- NCT07878286
- Testing
- Central Sensitization Inventory, The Multidimensional Assessment of Interoceptive Awareness scale-2, Revised Fibromyalgia Impact Questionnaire
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
Disuse Osteoporosis, Atrophy, Disuse
Activity Dependent Rehabilitation Model to Improve Bone and Muscle Outcomes
For many after spinal cord injury (SCI) there is immobilization, muscle atrophy, bone loss, fracture risk during transferring (or falls), and the risk of secondary complications, and increase in attendance care and cost.
- Conditions
- Disuse Osteoporosis, Atrophy, Disuse, Nervous System, Structural; Marker
- Trial name
- NCT02309983
- Testing
- Electrical Stimulation, Stand Retraining with Body Weight Support (BWS)
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Kessler Foundation
Contracture, Spasticity, Muscle
Effect of Cryoneurolysis on Pain in Patients With Hand Contracture.
Contracture which is defined as a limitation of the maximum passive range of motion due to changes in periarticular soft tissue can contributes to severe pain and increased disabilities.
- Trial name
- NCT06051656
- Where
- Canada
- Volunteers
- 25 people
- Sponsor
- Vancouver Island Health Authority
Lateral Epicondylitis, Elbow Tendinopathy
Upper Extremity-based Exercises and Elbow-focused Exercises in LET
The aim of the study is to investigate the effects of rotator cuff and scapular muscle strengthening exercises applied in addition to the 8-week elbow focused rehabilitation program in lateral elbow tendinopathy, by comparing it…
- Trial name
- NCT05809622
- Testing
- Elbow focused rehabilitation, Scapular and rotator cuff muscles strengthening
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people
- Sponsor
- Istanbul University - Cerrahpasa
Systemic Lupus Erythematosus (SLE), Diffuse Systemic Sclerosis
YTS109 in Pediatric Relapsed/Refractory Autoimmune Diseases
This exploratory, single-arm, open-label study will evaluate the safety and preliminary efficacy of YTS109 cell therapy in pediatric patients with relapsed/refractory autoimmune diseases, including systemic lupus erythematosus…
- Conditions
- Systemic Lupus Erythematosus (SLE), Diffuse Systemic Sclerosis, Idiopathic Inflammatory Myopathies (IIMs), ANCA Associated Vasculitis (AAV)
- Trial name
- NCT07439029
- Testing
- YTS109 cell
- Where
- China
- Volunteers
- 12 people
- Sponsor
- Children's Hospital of Fudan University
Brain Injuries, Disorder of Consciousness
Long Term Effects of Soft Splints on Stroke Patients and Patients With Disorders of Consciousness
The purpose of this study is to assess the effects on upper limb spasticity of soft splints worn during three weeks three hours a day by patients with stroke or disorders of consciousness.
- Conditions
- Brain Injuries, Disorder of Consciousness, Stroke, Spasticity as Sequela of Stroke
- Trial name
- NCT03008486
- Testing
- Real soft splint (6 cm)
- Where
- Belgium
- Volunteers
- 12 people
- Sponsor
- Géraldine Martens
Myofascial Pain Syndromes, Massage
Manual Therapy Techniques for Cervical Pain: Algometric Evaluation
The main objective of this study is to evaluate the effectiveness of different manual therapy techniques in the treatment of cervical pain related to the upper trapezius muscle.
- Conditions
- Myofascial Pain Syndromes, Massage, Stretching
- Trial name
- NCT06982456
- Testing
- Manual Therapy on the Upper Trapezius with or without Passive Stretching
- Where
- Spain
- Volunteers
- 105 people
- Sponsor
- Universidad de Murcia
Tendinopathy
The Effect of Multiple Injection of Platlet-rich Plasma in Chronic Patellar Tendinopathy
According to previous studies, the effect of PRP to patellar tendinopathy could last longer. However, the type, concentration, time and frequent of injection are still debated。 This study is to understand the effect of multiple…
- Trial name
- NCT03986372
- Testing
- Platlet-rich plasma
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Chang Gung Memorial Hospital
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