Clinical trials: MYOPATHY
Myofacial Pain, Myofacial Pain Syndrome
Evaluation of the Effect of Adding Sodium Bicarbonate to Lidocaine in the Treatment of Myofascial Pain Syndrome
This study is designed to evaluate a method to improve the treatment of myofascial pain syndrome (MPS), a common condition that causes muscle pain, tenderness, and reduced movement due to the presence of trigger points in…
- Conditions
- Myofacial Pain, Myofacial Pain Syndrome, Myofacial Pain Syndromes, Trigger Point Pain, Myofascial
- Trial name
- BIC-LIDO-MPS (NCT07572994)
- Testing
- Lidocaine 2 %, Lidocaine + Sodium Bicarbonate
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Cairo University
Fibromyalgia
Effect of EMDR in the Treatment of Fibromyalgia
The goal of this randomized-controlled study is to investigate the impact of EMDR therapy on fibromyalgia symptoms, depression, sleep quality, and traumatic stress in fibromyalgia patients.
- Trial name
- EMDR (NCT06265194)
- Testing
- EMDR, TAU
- Volunteers
- 79 people
- Sponsor
- Academy of Therapeutic Sciences, Turkey
Arthritis, Osteoarthritis Hand
Novel Splinting Technique Using 3D Models
The purpose of the study is to determine the feasibility of a non-contact custom splint fabrication method for patients with chronic diseases suffering from hypersensitive skin or compromised skin integrity.
- Conditions
- Arthritis, Osteoarthritis Hand, Scleroderma, Systemic, Scleroderma, Diffuse
- Trial name
- NCT05351060
- Testing
- Custom Fabricated Splint
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Giovanna Fichera
Neck Pain, Neck Pain Musculoskeletal
Neck Musculoskeletal Symptoms Among Turkish Endodontists
This observational study aims to evaluate the prevalence, severity, and characteristics of neck musculoskeletal symptoms among Turkish endodontists.
- Conditions
- Neck Pain, Neck Pain Musculoskeletal, Musculoskeletal Assessment, Musculoskeletal Disorder of the Neck
- Trial name
- ENDO-NECK (NCT07516782)
- Testing
- No intervention (observational study)
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Atlas University
Fibromyalgia
Effects of Box Breathing Exercise in Patients With Fibromyalgia
Fibromyalgia is a chronic condition that can cause widespread pain, sleep problems, fatigue, gastrointestinal symptoms, and reduced comfort.
- Trial name
- NCT07722923
- Testing
- Box Breathing Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Artvin Coruh University
Bethlem Myopathy, Ullrich Congenital Muscular Dystrophy 1, Digenic, Col6A1/Col6A2
Global Registry for COL6-related Dystrophies
The Global Registry for COL6-related dystrophies (www.collagen6.org) is a database for individuals who have been diagnosed with Bethlem Myopathy, Ullrich Congenital Muscular Dystrophy (UCMD) or an intermediate form of these…
- Conditions
- Bethlem Myopathy, Ullrich Congenital Muscular Dystrophy 1, Digenic, Col6A1/Col6A2, Ullrich Congenital Muscular Dystrophy 1, Autosomal Recessive, Ullrich Congenital Muscular Dystrophy 1, Autosomal Dominant
- Trial name
- NCT04020159
- Testing
- Patient Registry
- Where
- United Kingdom
- Volunteers
- 1,000 people
- Sponsor
- Newcastle-upon-Tyne Hospitals NHS Trust
X-Linked Myotubular Myopathy
A Study to Check Liver Health in Boys With XLMTM, a Serious Genetic Muscle Condition
XLMTM (X-linked myotubular myopathy) is a serious genetic muscle condition. It is caused by changes in the MTM1 gene which stops or slows down normal muscle development, causing severe muscle weakness.
- Trial name
- EXCEL (NCT06581146)
- Testing
- No Intervention
- Where
- 11 sites in United States, Canada and 1 more
- Volunteers
- 50 people
- Sponsor
- Astellas Gene Therapies
Hemiplegia, Spastic
Influence of Radial Extracorpeal Shock Wave in Hemiplegic Shoulder Patients
The purposes of this study are to examine sonographic structural changes pre and post the radial extracorporeal shock wave intervention in hemiplegic shoulder pain, and to assess the relationships between sonographic structural…
- Trial name
- NCT04859673
- Testing
- radial extracorpeal shock wave
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Delta University for Science and Technology
Temporomandibular Disorder
Efficacy and Safety of JHG002 for Chronic Temporomandibular Joint Dysfunction: A Multicenter Randomized Controlled Trial
This study is a 2-arm parallel, assessor blinded, multi-centre, randomised controlled trial.
- Trial name
- NCT04087005
- Testing
- hominis placental pharmacopuncture
- Where
- 2 sites in South Korea
- Volunteers
- 82 people
- Sponsor
- Jaseng Medical Foundation
Fibromyalgia
Cymbalta for Fibromyalgia Pain - Predictive Value of Small Fiber Changed
Subjects with Fibromyalgia who respond to Duloxetine have specific nerve fiber characteristics. This can be used to predict which future patients will respond to Duloxetine.
- Trial name
- NCT01619566
- Testing
- Duloxetine
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, San Diego
Shoulder Impingement Syndrome, Adhesive Capsulitis
Sayed Issa's Hybrid Shoulder Arthroscopic-Open Surgical Management (HSSM)
Sayed Issa's Hybrid Shoulder Arthroscopic-Open Surgical Management (HSSM) is a limited lateral approach to the shoulder arthroscopically guided.
- Conditions
- Shoulder Impingement Syndrome, Adhesive Capsulitis, Rotator Cuff Tear, Hill-Sachs Lesion
- Trial name
- HLSSM (NCT05897866)
- Testing
- Sayed Issa's Hybrid Shoulder Arthroscopic-Open Surgical Management
- Where
- Syria
- Volunteers
- 44 people
- Sponsor
- Issa, Abdulhamid Sayed, M.D.
Post-Exercise Recovery, Muscle Soreness
Shower Gel and Participant-Reported Post-Exercise Soreness in Regular Exercisers
The objective of this study is to evaluate any potential claims for a topical shower gel product about perceived recovery and other aspects of user experience and consumer satisfaction following HYROX exercise training.
- Trial name
- NCT07908290
- Testing
- Topical shower gel, Comparator
- Where
- Ireland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The Humanix
Dupuytren Contracture
BOND Study: the Benefit Of Night Splinting in Dupuytrens'
The BOND study is a prospective, randomised single blinded controlled trial to assess the effect of night splinting in patients who have had collagenase injection and manipulation therapy for Dupuytren's Contracture.
- Trial name
- BOND (NCT03031080)
- Testing
- Thermoplastic Hand Splint
- Where
- United Kingdom
- Volunteers
- healthy volunteers welcome
- Sponsor
- Liverpool University Hospitals NHS Foundation Trust
Myositis, Myasthenia Gravis
Rituximab for the Treatment of Refractory Inflammatory Myopathies and Refractory Myasthenia Gravis
The traditional treatment of inflammatory myopathies (IM) and generalized myasthenia gravis (MG) is immunosuppressive therapy, usually beginning with corticosteroids.
- Trial name
- FORCE (NCT00774462)
- Testing
- Rituximab
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Intra-Abdominal Hypertension, Abdominal Compartment Syndrome
WSACS 2026 Delphi Consensus on the Practical Management of Intra-abdominal Hypertension and Abdominal Compartment Syndrome
The Abdominal Compartment Society (WSACS) is updating its 2013 clinical practice guidelines on intra-abdominal hypertension (IAH) and the abdominal compartment syndrome (ACS).
- Trial name
- WSACS-DELPHI-2 (NCT07915362)
- Testing
- Delphi structured interview via online survey
- Where
- Poland
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Medical University of Lublin
Post Operative Pain, Impacted Third Molar Tooth
Jaw Muscle Pain Post Wisdom Molar Surgery
The proposed design is a triple-blind, placebo-controlled randomized prospective phase II trial to assess the feasibility of employing the Temporo-masseteric Nerve Block (TMNB) injection to decrease jaw muscle pain, overall pain…
- Conditions
- Post Operative Pain, Impacted Third Molar Tooth, Muscle Pain
- Trial name
- NCT07094542
- Testing
- Temporo-masseteric Nerve Block Injection, Oral Pain Medications only
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Rutgers, The State University of New Jersey
Motor Neuron Disease, Amyotrophic Lateral Sclerosis (ALS)
Safety and Efficacy on Spasticity Symptoms of a Cannabis Sativa Extract in Motor Neuron Disease
The clinical primary hypothesis is that there will be a difference between a Cannabis Sativa extract and placebo in their effect on spasticity in Motor Neuron Disease (MND) patients with signs of involvement of the upper motor…
- Trial name
- CANALS (NCT01776970)
- Testing
- Cannabis Sativa extract Oromucosal spray
- Where
- 4 sites in Italy
- Volunteers
- 60 people
- Sponsor
- Ospedale San Raffaele
Musculoskeletal Pain, Breast Cancer
Phase 3 Study Randomized Evaluating the Efficacy of Auriculotherapy in Patients With Musculoskeletal Pain by Aromatase Inhibitors
Auriculotherapy is a complementary medicine, with few side effects, without contraindication, inexpensive and not very restrictive.Its efficacy has been found in several tests especially for the treatment of intraoperative pain.
- Trial name
- TRIPLE-A (NCT03096041)
- Testing
- Auriculotherapy for analgesic use
- Where
- 7 sites in France
- Volunteers
- 197 people
- Sponsor
- Centre Francois Baclesse
Cerebral Palsy, Spastic
Whole Body Vibration in Children With Cerebral Palsy
Some positive effects of whole body vibration applications in reducing spasticity, improving walking ability, and increasing walking speed have been reported in children with CP, but the evidence is not strong enough.
- Trial name
- CP (NCT05636241)
- Testing
- conventional physiotherapy program, whole body vibration training program
- Where
- Turkey (Türkiye)
- Volunteers
- 13 people
- Sponsor
- Kutahya Health Sciences University
Muscular Dystrophy, Duchenne
Modified Diet Trial: A Study of SMT C1100 in Paediatric Patients With DMD Who Follow a Balanced Diet
Placebo-controlled, multi-centre, randomized, double-blind dose escalation study. The aim is to evaluate the pharmacokinetics (PK) and safety of SMT C1100 in paediatric patients with Duchenne Muscular Dystrophy (DMD) who follow a…
- Trial name
- NCT02383511
- Testing
- SMT C1100
- Where
- 4 sites in United Kingdom
- Volunteers
- 12 people
- Sponsor
- Summit Therapeutics
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