Clinical trials: MYOPATHY
Smoking Cessation, Body Composition, Beneficial
The Effect of Cigarette Smoking / Smoking Cessation on Skeletal Muscle Mass, Strength and Functional Capabilities
Tobacco smoke is probably the single most significant source of toxic chemicals that humans are exposed to. Smoking is associated with a variety of pathological conditions such as cardiovascular and pulmonary diseases.
- Conditions
- Smoking Cessation, Body Composition, Beneficial, Muscle Weakness
- Trial name
- NCT02128048
- Testing
- Assessment of body composition and muscle function
- Where
- Israel
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
de Quervain's Tenosynovitis
Sinew Acupuncture for de Quervain's Tenosynovitis
Background: Prevalence of de Quervain's Tenosynovitis (dQt) is estimated at 0.5% among men and 1.3% among women. As there is an increasing length of time in smart phone usage, the prevalence is believed to be higher in the…
- Trial name
- NCT03472443
- Testing
- acupuncture
- Where
- Hong Kong
- Volunteers
- 68 people
- Sponsor
- The University of Hong Kong
Long-chain 3-hydroxyacyl-CoA Dehydrogenase Deficiency, Carnitine Palmitoyltransferase Deficiency 2
Oral Ketones and Exercise Among Patients With Long-chain Fatty Acid Oxidation Disorders
The purpose of the study is to determine if an oral ketone beverage is safe and well-tolerated during moderate intensity exercise in participants with long-chain fatty acid oxidation disorders and if it will raise blood ketones…
- Conditions
- Long-chain 3-hydroxyacyl-CoA Dehydrogenase Deficiency, Carnitine Palmitoyltransferase Deficiency 2, Very Long Chain Acyl Coa Dehydrogenase Deficiency, Trifunctional Protein Deficiency
- Trial name
- NCT05411835
- Testing
- Nutritional Ketone Supplement
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Oregon Health and Science University
Muscle Spasticity, Spinal Cord Injury
Comparing Upper Limb Surgery and Botulinum Toxin for Spasticity: A Paired Design Study
Spasticity is a common complication following central nervous system injuries. Left untreated, spasticity can lead to various complications, hindering activities of daily living and diminishing independence.
- Conditions
- Muscle Spasticity, Spinal Cord Injury, Stroke, Traumatic Brain Injuries
- Trial name
- NCT06733025
- Testing
- Tendon lengthening surgery, BoNT Injections
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- Vastra Gotaland Region
Duchenne Muscular Dystrophy
Historically Controlled Trial of Corticosteroids in Young Boys With Duchenne Muscular Dystrophy
While it has been known for many years that corticosteroid use benefits boys with Duchenne Muscular dystrophy (DMD), most clinicians do not consider treating until after age 3 or 4 years of age.
- Trial name
- NCT02167217
- Testing
- Prednisolone
- Where
- 6 sites in United States
- Volunteers
- 25 people
- Sponsor
- Washington University School of Medicine
Alopecia Areata, Depressive Episode
The Epidemiology, Management, and the Associated Burden of Related Conditions in Alopecia Areata
This study series consists of four related studies and aims to explore and describe many important elements of alopecia areata over three key areas: (1) the current epidemiology of alopecia areata, (2) the prevalence and…
- Conditions
- Alopecia Areata, Depressive Episode, Recurrent Depressive Disorder, Anxiety Disorders
- Trial name
- NCT04239521
- Testing
- Exposure of interest (studies 2 & 3).
- Where
- United Kingdom
- Volunteers
- 51,955 people
- Sponsor
- Momentum Data
Duchenne Muscular Dystrophy
This is a Study to Get More Information About Non Ambulatory Boys & Men With Duchenne Muscular Dystrophy
Many therapeutic trials in DMD exclude non-ambulatory boys and men. Rate of progression in these non-ambulatory patients has been studied but consensus has not been reached for what measures are most reliable and reproducible.
- Trial name
- DMD (NCT01098708)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Washington University School of Medicine
Lateral Epicondylitis
Physiotherapy Applications in Lateral Epicondylitis
This study aims to compare the effectiveness of extracorporeal shock wave therapy (ESWT) and high-intensity laser therapy (HILT) in improving pain, grip strength, and function in patients with lateral epicondylitis.
- Trial name
- NCT07028840
- Testing
- Physiotherapy, Extracorporeal Shock Wave Therapy (ESWT), High-Intensity Laser Therapy (HILT)
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Pamukkale University
Fibromyalgia, Pain
Catastrophizing and Virtual Reality's Impact on Pain in Patients With Fibromyalgia
This study evaluates the potential association between Virtual Reality, pain catastrophizing thoughts and pain measures in fibromyalgia.
- Trial name
- NCT04294914
- Testing
- Cold Pressor Test, Cold Pressor Test + Virtual Reality
- Where
- Denmark
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Aalborg University
Fibromyalgia
Comparison of Muscle Energy Techniques and Breathing Exercises for Functional Improvement in Fibromyalgia
This study is planned to compare the effects of Muscle Energy Techniques (MET) with breathing exercises for improving functional outcomes in patients with fibromyalgia. A randomized controlled trial will be conducted.
- Trial name
- MET (NCT04674878)
- Testing
- METs, Breathing exercise group
- Where
- Pakistan
- Volunteers
- 26 people
- Sponsor
- Riphah International University
Fibromyalgia
Neuromodulatory Effects of Transcranial Pulsed Current Stimulation in Fibromyalgia
Fibromyalgia (FM) is a functional syndrome characterized by musculoskeletal, diffuse and persistent (> 3 months) chronic pain, that is also characterized by sleep disturbances, fatigue, humor changes and cognitive and…
- Trial name
- NCT05321693
- Testing
- Transcranial Pulsed Current Stimulation
- Where
- 2 sites in Brazil
- Volunteers
- 70 people
- Sponsor
- Centro Universitario La Salle
Becker Muscular Dystrophy
Safety and Biomarker Response to (+)-Epicatechin in Becker Muscular Dystrophy
This is a Phase 1, open-label, dose escalation study aimed at evaluating the safety, early efficacy and potential biomarkers of (+)-epicatechin in patients with Becker or Becker-like Muscular Dystrophy (BMD).
- Trial name
- NCT04386304
- Testing
- (+)-Epicatechin
- Where
- 3 sites in United States
- Volunteers
- 22 people
- Sponsor
- Epirium Bio Inc.
Temporomandibular Joint Disorders
Correlation Between Craniovertebral Angle and Temporomandibular Disorders
The purpose of study was investigate the correlation between craniovertebral angle and Temporomandibular disorders.
- Trial name
- NCT07522749
- Where
- Egypt
- Volunteers
- 68 people
- Sponsor
- Cairo University
Muscle Recovery
Investigating the Efficacy of Low or High Dose Tart Cherry on Recovery From Exercise Induced Muscle Damage and Establishing Its Molecular Mechanisms of Action
To determine the dose-response effects of 10-day tart cherry product consumption (0, 30 ml, and 60 ml) on knee extensor isometric strength 24-h and 48-h after muscle damaging exercise and to elucidate the mechanisms of action for…
- Trial name
- NCT04725149
- Testing
- 500 ml base solution, 500 ml containing 30 ml tart cherry concentrate diluted with water and base solution, 500 ml containing 60 ml tart cherry concentrate diluted with water only
- Where
- United Kingdom
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- PepsiCo Global R&D
Muscle Weakness
Effects of Creatine Supplementation on Muscle Mass and Function Among Older Women Subjected to Resistance Training
To determine, in a double blind trial, the effects of creatine supplementation during 12 weeks on muscle mass and function of community living older women subjected to resistance training.
- Trial name
- NCT02188849
- Testing
- Resistance exercise training, Creatine
- Where
- Chile
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Chile
Bruxism, Muscle Disorder
Effect of Spinal Manipulation on Electromyography of the Masseter Muscle
Research Problem: To know the immediate effects of high speed and low amplitude cervical manipulation on the electromyographic activity of the masseter muscles of physiotherapy students at the University of the Americas Course…
- Trial name
- NCT05138926
- Testing
- Cervical Manipulation
- Where
- Chile
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Americas - Chili
Fibromyalgia
Shugan Dingtong Decoction in the Treatment of Fibromyalgia
Fibromyalgia (FM) is a syndrome characterized by chronic and widespread musculoskeletal pain, fatigue sleep disturbances and cognitive and somatic symptoms.
- Trial name
- NCT05508516
- Testing
- Shugan Dingtong decoction, Duloxetine Hydrochloride
- Where
- China
- Volunteers
- 72 people
- Sponsor
- China-Japan Friendship Hospital
Duchenne Muscular Dystrophy, Cardiomyopathy
HOPE-Duchenne (Halt cardiomyOPathy progrEssion in Duchenne)
Male participants with cardiomyopathy secondary to Duchenne muscular dystrophy (DMD) meeting all inclusion and no exclusion criteria will be randomized. All participants will be at least 12 years of age.
- Trial name
- HOPE (NCT02485938)
- Testing
- Allogeneic Cardiosphere-Derived Cells (CAP-1002)
- Where
- 3 sites in United States
- Volunteers
- 25 people
- Sponsor
- Capricor Inc.
Polymyositis, Dermatomyositis
Phase 2 Trial to Evaluate the Efficacy, Safety of Allogeneic Mitochondria (PN-101) in Patients With Refractory Polymyositis or Dermatomyositis
The efficacy of PN-101 in subjects with polymyositis or dermatomyositis will be evaluated at Week 12 using IMACS-TIS in comparison with the placebo control group.
- Trial name
- NCT07122648
- Testing
- PN-101
- Where
- 5 sites in South Korea
- Volunteers
- 36 people
- Sponsor
- Paean Biotechnology Inc.
Muscle Spasticity
Quantitative Evaluation of Muscle Stiffness in Neurological Patients With Muscle Overactivity
Objective: 1. to investigate reliability, validity and responsiveness of shearwave elastography (SWE) to assess muscle stiffness of overactive upper or lower limb muscles in different angle joint positions in patients with…
- Trial name
- NCT05510726
- Testing
- shearwave elastography
- Where
- Belgium
- Volunteers
- 30 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
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