Clinical trials: Macular Detachment
Posterior Capsule Opacification, Retinal Degeneration
Changes of Macular Pigment and Parameters of Eyes After YAG Laser Treatment in Cases With Capsule Opacification
It has been hypothesized that potential effects of laser Nd: YAG laser posterior capsulotomy may affect macular pigment as well as choroidal thickness, macular thickness and anterior chamber parameters, so it was aimed to…
- Conditions
- Posterior Capsule Opacification, Retinal Degeneration, Retinal Detachment, Anterior Chamber Angle Congestion
- Trial name
- NCT03321253
- Testing
- Nd: YAG laser posterior capsulotomy
- Volunteers
- 38 people
- Sponsor
- Afyon Kocatepe University Hospital
Macular Holes, Retinal Detachment
Amniotic Membrane Visio-AMTRIX in Recurrent Macular Hole
The purpose of this open, multicenter trial is to assess the impact of the use of an amniotic membrane graft on the closure of macular hole-associated retinal detachment in patients with failed previous macular surgery.
- Trial name
- NCT05191628
- Testing
- Visio-AMTRIX
- Where
- France
- Volunteers
- 12 people
- Sponsor
- TBF Genie Tissulaire
Proliferative Diabetic Retinopathy, Macular Degeneration
Analysis of Aqueous and Vitreous Humor
Clinical Retina research studies often collect aqueous samples in hopes of estimating levels of drug or cytokines in the vitreous. Little is known about how well vitreous and aqueous correlate.
- Conditions
- Proliferative Diabetic Retinopathy, Macular Degeneration, Macular Hole, Neovascular Glaucoma
- Trial name
- ARK (NCT02067013)
- Testing
- Ranibizumab, No Ranibizumab
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- California Retina Consultants
Proliferative Diabetic Retinopathy
Macular Tractional Retinoschisis in Proliferative Diabetic Retinopathy
Objective: To evaluate the clinical manifestations and surgical prognosis of macular tractional retinoschisis in proliferative diabetic retinopathy. Design: Retrospective case series.
- Trial name
- NCT01312207
- Where
- Taiwan
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Pigment Epithelial Detachment
Aflibercept in Patients With Pigment Epithelial Detachments (PED)
Uncontrolled single site non randomized non interventional study to determine the safety and efficacy of intravitreal injections of Aflibercept in patients with recent vision loss due to retinal pigment epithelial detachment…
- Trial name
- NCT03370380
- Testing
- Aflibercept
- Where
- Germany
- Volunteers
- 18 people
- Sponsor
- University Hospital Muenster
Epiretinal Membrane Surgery
Post-surgical Functional Results in Patients With Epiretinal Membrane Undergoing Controlled Macular Detachment
This study aims to evaluate postsurgical functional changes in patients with advanced epiretinal membrane (ERM) (stages 3 and 4) by integrating a controlled macular detachment with a balanced salt solution to the conventional ERM…
- Trial name
- DMER25 (NCT07095907)
- Testing
- Pars plana vitrectomy with epiretinal membrane peeling and controlled macular detachment
- Where
- Mexico
- Volunteers
- 36 people
- Sponsor
- Asociación para Evitar la Ceguera en México
Retinal Detachment
Pneumatic Retinopexy Versus Vitrectomy With Gas for Retinal Detachment Due to Myopic Macular Hole
To undertake a prospective randomized clinical study for treating retinal detachment due to myopic macular holes, utilizing pneumatic retinopexy versus pars plana vitrectomy with gas tamponade.To determine the efficiency of…
- Trial name
- RDMH (NCT00485199)
- Testing
- Pneumatic Retinopexy, Vitrectomy with Gas
- Where
- 14 sites in China
- Volunteers
- 231 people
- Sponsor
- Peking University
Rhegmatogenous Retinal Detachment, Primary Vitrectomy
Primary Vitrectomy With Silicone Oil or SF6 for Rhegmatogenous Retinal Detachment
Rhegmatogenous retinal detachment (RRD) is the separation of the neurosensory retina from the retinal pigment epithelium caused by the presence of a break that leads to the passage of fluid from the vitreous cavity into the…
- Trial name
- NCT05377606
- Testing
- Pars plana vitrectomy with silicone oil, Pars plana vitrectomy with SF6
- Where
- Egypt
- Volunteers
- 62 people
- Sponsor
- Cairo University
Age-Related Macular Degeneration (AMD), Diabetic Retinopathy (DR)
Proteomic Biomarker Identification in Age-Related Macular Degeneration, Diabetic Retinopathy and Retinal Detachment
This prospective interventional translational study aims to identify and validate protein biomarkers associated with major ophthalmological diseases, including age-related macular degeneration, diabetic retinopathy (DR), and…
- Conditions
- Age-Related Macular Degeneration (AMD), Diabetic Retinopathy (DR), Retinal Detachment
- Trial name
- PRO Project (NCT07500324)
- Testing
- Biological Sample Collection
- Where
- Italy
- Volunteers
- 260 people
- Sponsor
- Fondazione G.B. Bietti, IRCCS
Macular Hole, RPE Detachment
Comparison of a Spectral OCT/SLO With the Stratus OCT for Imaging Various Retinal Pathologies
The purpose of this study is to compare the newly released Spectral OCT/SLO (OTI, Toronto, Canada) with the Zeiss Stratus OCT (Carl-Zeiss Meditec, Dublin, CA) with regards to the quality of the images obtained as well as the ease…
- Conditions
- Macular Hole, RPE Detachment, Epiretinal Membrane, Posterior Vitreous Detachment
- Trial name
- NCT00408720
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- The New York Eye & Ear Infirmary
Retinal Detachment, Macular Edema
OCT Macula Biomarkers Before Silicone Oil Removal and Visual Outcome After Silicone Oil Removal
Silicone oil is commonly used as a temporary intraocular tamponade to support the retina during vitreoretinal surgery for complex retinal detachment and other severe retinal conditions.
- Conditions
- Retinal Detachment, Macular Edema, Silicone Oil Tamponade, Epiretinal Membrane
- Trial name
- NCT07865468
- Volunteers
- 30 people
- Sponsor
- Assiut University
Vitrectomy, Retinal Detachment
Pars Plana Vitrectomy With 25-gauge 20000 Cpm, Bevel-tip Cutter
Report efficiency and clinical outcomes using 25-gauge, bevel-tip, 20000 cut per minute vitrectomy probe among eyes with various vitreo-retinal diseases
- Conditions
- Vitrectomy, Retinal Detachment, Vitreous Hemorrhage, Macular Holes
- Trial name
- HYPE (NCT04404296)
- Testing
- 25-gauge, bevel-tip, 20000 cut per minute pars plana vitrectomy
- Where
- Philippines
- Volunteers
- 50 people
- Sponsor
- Peregrine Eye and Laser Institute
Retinal Detachment, Epiretinal Membrane
PIONEER: Intraoperative and Perioperative OCT Study
OCT provides high-resolution information regarding the anatomic structure of the tissues of the eye in a 2-dimensional and 3-dimensional view. Much of this information is not able to be recognized by a clinician.
- Conditions
- Retinal Detachment, Epiretinal Membrane, Macular Hole, Fuchs Endothelial Dystrophy
- Trial name
- PIONEER (NCT02423161)
- Where
- United States
- Volunteers
- 750 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Retinal Detachment, Macular Pucker
Zeiss RESIGHT Disposable Lenses Evaluation Study
To evaluate the intra-operative efficacy of a new intra-operative viewing device.
- Conditions
- Retinal Detachment, Macular Pucker, Macular Holes, Vitreomacular Traction
- Trial name
- RESIGHT (NCT05860985)
- Testing
- ZEISS disposable
- Where
- Belgium
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Retinal Detachment, Macular Hole
Head Position Monitoring After Pars Planar Vitrectomy
In ophthalmic surgical practice, particularly for treating retinal detachment and macular hole disorders, vitrectomy procedures are routinely performed to remove the vitreous body followed by the injection of tamponade agents…
- Trial name
- HPMPPV (NCT06985030)
- Testing
- gyroscope embedded eye-sheild
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Seoul National University Hospital
Macular Detachment, Macular Retinoschisis
Macular Detachment Associated With Intrachoroidal Cavitation
Evaluation of clinical characteristics and surgical outcome for macular detachment associated with peripapillary intrachoroidal cavitation with or without pathologic myopia.
- Conditions
- Macular Detachment, Macular Retinoschisis, Intrachoroidal Cavitation
- Trial name
- NCT01959724
- Testing
- Vitrectomy
- Where
- Japan
- Volunteers
- 69 people
- Sponsor
- Kyorin University
Diabetic Retinopathy, Macular Traction Retinal Detachment
Intravenous Tranexamic Acid in Diabetic Macular TRD Surgeries
The goal of this observational study is to learn about safety and results of peroperative and intraoperative intravenous Tranexamic acid for diabetic macular tractional detachment eye surgeries .
- Trial name
- TXA-DMTRD (NCT06560073)
- Where
- India
- Volunteers
- 102 people
- Sponsor
- Ahalia Foundation Eye Hospital
Macular Retinoschisis, Macular Detachment
Macular Retinoschisis and Detachment Associated With Glaucomatous Optic Neuropathy
Clinical features, optical coherence tomography findings and surgical outcome in eyes with macular retinoschisis and detachment with normal tension glaucoma but without optic disc pit or high myopia were evaluated.
- Conditions
- Macular Retinoschisis, Macular Detachment, Normal Tension Glaucoma
- Trial name
- NCT01862627
- Testing
- Optical coherence tomography
- Where
- Japan
- Volunteers
- 11 people
- Sponsor
- Kyorin University
Cataract
Caffeine and Cataract After Pars Plana Vitrectomy
Assessment of cataract development in patients with regular caffeine consumption and those without caffeine consumption after pars plana vitrectomy.
- Trial name
- NCT06358664
- Testing
- Pars plana vitrectomy
- Where
- Austria
- Volunteers
- 74 people
- Sponsor
- Vienna Institute for Research in Ocular Surgery
Retinal Detachment, Full Thickness Macular Hole
Inflammasomes in Cell Death in FTMH, ERM, and RRD
Prospective study evaluating the role of inflammasomes in cell death in retinal detachment, full thickness macular hole, and epiretinal membrane.
- Conditions
- Retinal Detachment, Full Thickness Macular Hole, Epiretinal Membrane
- Trial name
- NCT03332758
- Testing
- Pars plana vitrectomy, External drainage
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Allen C. Ho, MD