Clinical trials: Magnesium
Morbid Obesity
Impact of Pyloric Injection of Magnesium Sulfate and Lidocaine Mixture on Outcome After Sleeve Gastrectomy
Postoperative nausea and vomiting is a common adverse effect after sleeve gastrectomy, mostly due to increased intragastric pressure.
- Trial name
- NCT03729505
- Testing
- Pyloric injection of magnesium sulfate and lidocaine mixture, Pyloric injection of saline
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Mansoura University
Elevated Blood Glucose
Whole-Food Magnesium for Mental and Cardiometabolic Health
This randomized, double-blind, placebo-controlled clinical trial will evaluate the effects of daily supplementation with E-Z Mg™, a commercially available whole-food-based magnesium supplement, on sleep, mood, fatigue, and…
- Trial name
- NCT07865351
- Testing
- Low-Dose Whole-Food-Based Magnesium Supplement, Moderate-Dose Whole-Food-Based Magnesium Supplement
- Volunteers
- 45 people
- Sponsor
- George Mason University
Polycystic Ovary Syndrome, Obesity
Omega 3 Polyunsaturated Fatty Acids (PUFA) or Magnesium in Obese Polycystic Ovary Syndrome Patients
Polycystic ovary syndrome (PCOS) is the most prevalent endocrine disorder in reproductive age women. PCOS is usually characterized by an excessive androgen production, menstrual irregularities, and polycystic ovaries.
- Trial name
- OMgObPCOS (NCT02521753)
- Testing
- Metformin, Magnesium, PUFA
- Where
- Mexico
- Volunteers
- 123 people
- Sponsor
- Coordinación de Investigación en Salud, Mexico
Migraine
A Combination of Coenzyme Q10, Feverfew and Magnesium for Migraine Prophylaxis : a Prospective Observational Study
Adult patients suffering from migraine according to the criteria of the International Headache Society were enrolled by general practitioners (≥2 migraine attacks during previous month; exclusion of chronic migraine and…
- Trial name
- NCT02901756
- Testing
- Antemig
- Volunteers
- 132 people
- Sponsor
- PiLeJe
Patient With Neuropathic Pain
Impact of Oral Magnesium on Neuropathic Pain
Use lay language. The aim of this study is to evaluate on pain scores (neuropathic pain questionnaire and pain numeric scale) and on quality of life, the effect of oral magnesium intake on patients with neuropathic pain comparing…
- Trial name
- NCT01121653
- Testing
- Magnogene ® (magnesium)
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Clermont-Ferrand
Pain
Magnesium vs Placebo for Tonsillectomy
This study is a double-blind randomized controlled trial using intravenous magnesium versus placebo to determine if systemic magnesium can decrease postoperative pain in pediatric patients undergoing tonsillectomy.
- Trial name
- NCT02218424
- Testing
- Magnesium, Normal saline
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Hypertension, Endothelial Dysfunction
Effects of Magnesium Supplementation on Vascular Structure and Function in Hypertensive Patients
Introduction: Magnesium has been the target for many experimental and clinical studies due to the negative correlation between its serum and intracellular levels and the prevalence of hypertension and other cardiovascular…
- Trial name
- MG600 (NCT01151683)
- Testing
- magnesium
- Where
- Brazil
- Volunteers
- 52 people
- Sponsor
- Rio de Janeiro State University
Asthma
Bronchial Challenge Test of Magnesium-treated Asthmatics
The present study is part of a project titled 'Magnesium in asthma and chronic obstructive pulmonary disease'. The hypothesis of the main project is that a daily magnesium supplement will benefit patients with asthma and chronic…
- Trial name
- NCT01118923
- Testing
- Magnesium supplement (magnesium hydroxide/ -oxide)
- Where
- Denmark
- Volunteers
- 12 people
- Sponsor
- University of Aarhus
Alcohol Withdrawal Syndrome
MAGnesium Adjunction in Alcohol Withdrawal Syndrome: a Multicenter Assessment (MAGMA)
This study examine the efficacy of oral magnesium supplementation as an adjuvant therapy for decreasing intensity of alcohol withdrawal symptoms among inpatients requiring pharmacological treatment of their AWS.
- Trial name
- MAGMA (NCT03033823)
- Testing
- Magnesium
- Where
- 11 sites in France
- Volunteers
- 105 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Erosive Esophagitis
A Multicenter, Randomized, Double Blind, Double Dummy, Parallel-Group Efficacy Study Comparing 8 Weeks of Treatment With Esomeprazole Magnesium (40mg qd) to Lansoprazole (30mg qd) for the Healing of Erosive Esophagitis in Patients With Moderate or Severe Erosive Esophagitis
This study looks at the healing rates in patients with Erosive Esophagitis (EE) when treated with either esomeprazole or lansoprazole
- Trial name
- NCT00641602
- Testing
- Esomeprazole, Lansoprazole
- Volunteers
- 1,000 people
- Sponsor
- AstraZeneca
Atrial Fibrillation (AF), Magnesium Sulfate
Evaluation of the Role of Magnesium in Prevention of AF Post Cardiac Surgery
Atrial fibrillation (AF) is a common complication after cardiac surgery. Most studies suggest that the frequency ranges between 25-40%.
- Conditions
- Atrial Fibrillation (AF), Magnesium Sulfate, Post Cardiac Surgery Patients
- Trial name
- Magnesium AF (NCT06675500)
- Testing
- Magnesium sulphate
- Where
- Egypt
- Volunteers
- 130 people
- Sponsor
- Ain Shams University
Colorectal Cancer
A Multi-centre Study Comparing the Polyp Detection Rate of Two Different Types of Bowel Preparation: a 2-litre Solution (MOVIPREP®) Versus a Hyperosmotic and Stimulant Combined Low Volume Bowel Preparation (Sodium Picosulfate and Magnesium Citrate)
To compare the polyp and adenoma detection rate of MOVIPREP versus an oral Sodium Picosulfate/Magnesium Citrate solution.
- Trial name
- NCT01689792
- Testing
- MOVIPREP, CitraFleet
- Where
- Germany
- Volunteers
- 398 people
- Sponsor
- Norgine
Hand Fractures
The Efficacy and Safety of Magnesium Alloy Screw as a Novel Bioabsorbable Material in Patients Due to Hand Fractures
This study evaluates the safety and efficacy of biodegradable magnesium alloy screw, in patients with hand fractures who require internal fixation (to obtain a product license from the Ministry of Food and Drug Safety in Korea…
- Trial name
- NCT02456415
- Testing
- K-MET™ Bioresorbable Bone screw
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- U&I Corporation
Preterm Labor, Cerebral Palsy
Calcium Channel Blockers Compared to Magnesium Sulfate in Fetal Cerebral Blood Flow
The aim of this study is to investigate the possible use of calcium channel as a neuroprotectant in cases with PTL. This will be done by comparing the effect they have on cerebral blood vessels with the already established MgSo4.
- Trial name
- NCT02591004
- Testing
- Magesium sulphate, Nifedipine, Doppler on fetal middle cerebral artery
- Where
- Egypt
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Kasr El Aini Hospital
Healthy Volunteers
Clinical Evaluation of the Magnesium Absorption Kinetics in Human Plasma Upon Oral Intake of Magnesium-based Products
The goal of this clinical trial is to study the effect of four magnesium-based products on the magnesium concentration in plasma of volunteers upon oral intake.
- Trial name
- NCT06225349
- Testing
- Dietary supplementation with Microencapsulated Magnesium, Dietary supplementation with Magnesium Oxide, Dietary supplementation with Magnesium Citrate
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Bionos Biotech S.L.
Magnesium Deficiency, Heart Failure
The Impact of Magnesium on Exercise Tolerance, Quality of Life and Clinical Outcomes in Chronic Heart Failure Patients
Magnesium supplementation could improve cardiac performance. Patients with chronic heart failure (CHF) are magnesium deficient and we hypothesized that 1 year supplementation of oral magnesium comparted to placebo will improve…
- Trial name
- NCT03840226
- Testing
- Magnesium Oxide
- Where
- Israel
- Volunteers
- 320 people
- Sponsor
- Sheba Medical Center
Chronic Cough
Study to Investigate the Efficacy and Safety of SC0023, in Adults With Refractory or Unexplained Chronic Cough
This is a randomized, double-blind, placebo controlled cross-over study to investigate the efficacy and safety of SC0023 (an oral spray of magnesium based alkaline hypertonic divalent salt) in adults with refractory or…
- Trial name
- REACH (NCT07003347)
- Testing
- oral spray of MgCl2, Saline
- Where
- Saudi Arabia
- Volunteers
- 7 people
- Sponsor
- Kholood Altassan
Colorectal Cancer
Calcium: Magnesium Balance, Microbiota, and Necroptosis and Inflammation
Transient receptor potential melastatin 7 (TRPM7), a magnesium (Mg) -regulated chanzyme possessing both ion channel and kinase activities, has a much stronger affinity to Mg2+ than calcium (Ca)2+.
- Trial name
- NCT04229992
- Testing
- Magnesium glycinate
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Kidney Diseases, End-Stage Kidney Disease
Outcomes of a Higher vs. Lower Hemodialysate Magnesium Concentration (Dial-Mag)
Many patients on hemodialysis have low levels of magnesium. Magnesium is needed to keep the heart, kidneys, and other organs working properly.
- Conditions
- Kidney Diseases, End-Stage Kidney Disease, Hemodialysis
- Trial name
- NCT04079582
- Testing
- Dialysate magnesium formulation of 1.5 mEq/L (0.75 mmol/L)., Dialysate magnesium formulation of ≤1.0 mEq/L (≤0.5 mmol/L).
- Where
- Canada
- Volunteers
- 25,000 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Stroke, Cognition
Magnesium and Cognition After Stroke
Cognitive impairments such as memory impairments, word-finding difficulties, compromised orientation and perception are often observed in stroke patients.
- Conditions
- Stroke, Cognition, Magnesium, Neurologic Disorder
- Trial name
- NCT05132517
- Testing
- Kölner Neuropsychologische Screening für Schlaganfall-Patienten
- Where
- Germany
- Volunteers
- 80 people
- Sponsor
- BDH-Klinik Hessisch Oldendorf