Clinical trials: Magnesium Sulphate
Acute Ischemic Stroke
Intra-arterial Selective Hypothermic Magnesium Sulfate Infusion in Combination With Endovascular Thrombectomy in Acute Ischemic Stroke
The primary objective of this study is to estimate the safety and effectiveness of selective intra-arterial hypothermic magnesium sulfate infusion after endovascular thrombectomy in patients with acute ischemic stroke.
- Trial name
- ICE-MAG (NCT07163299)
- Testing
- Endovascular thrombectomy combination with selective intra-arterial hypothermic magnesium sulfate infusion (350 ml)., Endovascular thrombectomy combination with selective intra-arterial hypothermic magnesium sulfate infusion (500 ml)., Endovascular thrombectomy combination with selective intra-arterial hypothermic magnesium sulfate infusion (650 ml).
- Where
- China
- Volunteers
- 42 people
- Sponsor
- Capital Medical University
Preterm Labor
Efficacy and Safety of MgSO4 as Tocolytics Compared to Ritodrine in Preterm Labor
Ritodrine is the conventional and the only approved tocolytics in Korea(by KFDA), although it was withdrawn from the US market more than 10 years ago.
- Trial name
- NCT02538718
- Testing
- MgSO4, YTP(Ritodrine)
- Where
- 2 sites in South Korea
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Atrial Fibrillation
Low Versus High Dose Magnesium Sulfate in the Early Management of Rapid Atrial Fibrillation
Objective: To assess the efficacy and the safety of high (9g) and low dose (4.5g) of MgS in the immediate treatment of rapid AF.
- Trial name
- NCT00965874
- Testing
- Magnesium Sulfate high dose, Magnesium Sulfate low dose
- Where
- Tunisia
- Volunteers
- 450 people
- Sponsor
- University of Monastir
Magnesium Sulfate, Pregnancy; Pre-Eclampsia
The Effect of Magnesium Use in Reversal of Neuromuscular Block With Sugammadex
Magnesium therapy used for seizure prophylaxis in patients with preeclampsia. Magnesium has been shown to prolong the effect of nondepolarizing neuromuscular blocking agents (NMBA) and neostigmine used to reverse the effect of…
- Conditions
- Magnesium Sulfate, Pregnancy; Pre-Eclampsia, Neuromuscular Blockade
- Trial name
- NCT05558969
- Testing
- pregnant women taking magnesium
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Eskisehir Osmangazi University
Hemorrhage
Controlled Hypotension During Functional Endoscopic Sinus Surgery
It is very important to decrease the bleeding during functional endoscopic sinus surgery (FESS) in order to increase the visibility of the surgical site.
- Trial name
- NCT01956981
- Testing
- Magnesium Sulfate, Dexmedetomidine
- Volunteers
- 60 people
- Sponsor
- TC Erciyes University
Lumbar Spine Disc Herniation
Effects of Addition of Magnesium Sulfate in Spinal Anesthesia on Sensory-Motor Blocks and Postoperative Pain in Lumbar Disk Herniation Surgery
The purpose of this study is to Compare three methods of intrathecal bupivacaine; bupivacaine-fentanyl; bupivacaine-fentanyl-magnesium sulfate on sensory-motor blocks and postoperative pain in patients undergoing lumbar disk…
- Trial name
- NCT01843296
- Testing
- Magnesium Sulfate, Spinal Anesthesia, Bupivacaine
- Where
- Iran
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Isfahan University of Medical Sciences
Preeclampsia
Adding MgSO4 to Epidural Levobupivacaine in CS for Patients With Preeclampsia
This study aims at evaluating the effect of adding magnesium sulphate epidurally as an adjunct to levobupivacaine on the quality of anesthesia and perioperative pain relief in patients with preeclampsia undergoing elective…
- Trial name
- NCT02699827
- Testing
- Levobupivacaine hydrochloride, Magnesium sulphate, Saline 0.9%
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Mohamed Sayed Abdelhafez
Birth Asphyxia
Enhancing Neonatal Sucking Reflex: A Study on the Efficacy of Magnesium Sulphate in Severe Birth Asphyxia
Children's Hospital Multan is a tertiary care teaching hospital in South Punjab, the poorest and most backward area of Punjab, Pakistan, where a significant number of newborns suffer from birth asphyxia.
- Trial name
- NCT06468475
- Testing
- Magnesium Sulphate infusion
- Where
- Pakistan
- Volunteers
- 80 people
- Sponsor
- RESnTEC, Institute of Research
Muscle Relaxation
Effect of Magnesium Sulphate Pretreatment in Pediatric Abdominal Surgery
In this study, the investigators will compare the effect of magnesium sulphate pretreatment on the onset and duration of intense and deep neuromuscular Block of rocuronium versus Cis-Atracurium and on the period of no response to…
- Trial name
- MgSO4/MR (NCT05736744)
- Testing
- MgSO4, Cis-Atracurium
- Where
- 2 sites in Egypt
- Volunteers
- 58 people
- Sponsor
- Assiut University
Spine, Pain
Effect of Magnesium on Neuromonitoring
Intraoperative neurophysiologic monitoring (IONM) is commonly used during complex spinal surgery to monitor the integrity of neural structures and improve the perioperative safety profile.
- Conditions
- Spine, Pain, Spine Surgery, Spine Surgery With Neuromonitoring
- Trial name
- MgNm (NCT06975072)
- Testing
- Magnesium sulfate administration
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of California, San Francisco
Postoperative Pain
TAP Block in Laparoscopic Cholecystectomy.
Ultrasound-guided transversus abdominis plane block is now widely used in abdominal surgery. Recently, magnesium sulphate is used as adjuvant to local anesthetics.
- Trial name
- NCT03612947
- Testing
- Bupivacaine +magnesium sulphate, Bupivacaine only
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Preterm Labor, Cerebral Palsy
Calcium Channel Blockers Compared to Magnesium Sulfate in Fetal Cerebral Blood Flow
The aim of this study is to investigate the possible use of calcium channel as a neuroprotectant in cases with PTL. This will be done by comparing the effect they have on cerebral blood vessels with the already established MgSo4.
- Trial name
- NCT02591004
- Testing
- Magesium sulphate, Nifedipine, Doppler on fetal middle cerebral artery
- Where
- Egypt
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Kasr El Aini Hospital
Lumbar Disc Herniation, Emergence Agitation
Magnesium Sulfate for Prevention of Emergence Agitation in Lumbar Disc Surgery
In this retrospective study, the effect of intraoperative magnesium sulfate infusion on the incidence of postoperative emergence agitation was evaluated in adult patients who underwent elective lumbar microdiscectomy under…
- Conditions
- Lumbar Disc Herniation, Emergence Agitation, Magnesium Sulfate
- Trial name
- NCT07139847
- Testing
- Magnesium Sulfate Infusion, 0.9% Saline Infusion
- Volunteers
- 70 people
- Sponsor
- Ondokuz Mayıs University
Acute Severe Asthma
Compare Efficacy Nebulized and Intravenous Magnesium Sulphate in Thai Children
The purpose of this study is to determine whether nebulized magnesium sulphate is effective in the treatment of acute severe asthma when comparison with intravenous magnesium sulphate
- Trial name
- NCT02112305
- Testing
- isotonic magnesium sulphate, 50% magnesium sulphate
- Where
- Thailand
- Volunteers
- 40 people
- Sponsor
- Queen Sirikit National Institute of Child Health
Cesarean Section
MgSO4 as Adjuvants to Bupivacaine vs Neostigmine in TAP Block in Cesarean Section
The aim of this study is to compare the duration of analgesia obtained by addition of Neostigmine versus MgSO4 as adjuvants to bupivacaine in TAP block in patients undergoing Cesarean Section and to evaluate postoperative…
- Trial name
- NCT06513013
- Testing
- transversus abdominis plane (TAP) block in cesarean section, Magnesium sulfate, Neostigmine
- Where
- Egypt
- Volunteers
- 68 people
- Sponsor
- Assiut University
Bowel Preparation for Colonoscopy
Efficacy and Safety of Oral Sulfate Solution on Bowel Preparation for Colonoscopy
To evaluate whether oral sulfate solution used for colon cleaning in adults prior to colonoscopy was not inferior to 3-liter polyethylene glycol in the proportion of subjects with BBPS score (total colon) ≥6 after colonoscopy
- Trial name
- NCT05465889
- Testing
- Oral sulfate solution (OSS), Polyethylene Glycol Electrolyte
- Where
- China
- Volunteers
- 348 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital
Magnesium Sulfate, Postoperative Pain
Magnesium Sulfate Dose in Obese Patients.
Magnesium sulfate has been applied in various situations due to actual or potential benefits related to neuroprotection, treatment of eclampsia/pre-eclampsia, arterial hypertension, adrenergic reflex under laryngoscopy/intubation…
- Conditions
- Magnesium Sulfate, Postoperative Pain, Obesity
- Trial name
- NCT04003688
- Testing
- Magnesium sulfate through real weight group, Magnesium sulfate through ideal corrected weight group
- Where
- Brazil
- Volunteers
- 74 people
- Sponsor
- University of Sao Paulo General Hospital
Upper Abdominal Cancer Surgery
Effect of Adding Magnesium Sulphate as Adjuvant to Bupivacaine in Ultrasound Guided External Oblique Intercostal Plane Block in Upper Abdominal Cancer Surgery.to Assess the Total Postoperative Opioid Consumption in the First 24 h and Evaluate Post Operative VAS Score
double blind randomized controlled trial will be conducted on upper abdominal cancer surgery cases to study the effect of Adding Magnesium Sulphate as Adjuvant to Bupivacaine in Ultrasound Guided External Oblique Intercostal…
- Trial name
- NCT06677827
- Testing
- Bupivacaine, Magnesium Sulfate and Bupivacaine 0.125%
- Volunteers
- 68 people
- Sponsor
- Assiut University
Patients Undergoing Lumbar Fixation
Effect of Intraoperative Magnesium Sulphate on the Occurrence of Postoperative Delirium
Anaesthesia-related complications and mortality have been significantly reduced in the last years.(1) Nevertheless, anaesthesia-related side effects, such as post-operative delirium and sleep disturbances should not be…
- Trial name
- NCT05632159
- Testing
- Mg sulphate, conventional anaesthesia
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Beni-Suef University
Agitation, Pediatric Disorder
Addition of Magnesium Sulfate to Caudal to Prevent Postoperative Emergence Agitation.
Emergence agitation after sevoflurane anesthesia is still a problem needed to be solved.The aim of the study is to delineate the effect of caudal magnesium sulfate in children undergoing lower abdominal surgery to prevent…
- Trial name
- NCT02164773
- Testing
- Magnesium Sulfate, 0.9%normal saline
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Ain Shams University