Clinical trials: Magnesium Sulphate
Postoperative Pain
Effect of Lidocaine Versus Magnesium on Postoperative Pain in Spine Surgery
The goal in this work is to compare the effect of intravenous single-bolus lidocaine infusion versus intravenous single-bolus magnesium sulfate infusion on postoperative pain, emotional status and quality of life in patients…
- Trial name
- NCT04776369
- Testing
- Lidocaine IV, Magnesium Sulfate Injection, IV saline
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Haitham Mohammad Ahmad Mohammad
Post-mastectomy Pain Syndrome
Adding Magnesium Sulphate to Combined Pectointercostal Plane and Erector Spinae Plane Blocks for Acute and Chronic Post-Mastectomy Pain
Given the burden of chronic postmastectomy pain and the need for effective, opioid-sparing analgesia, the propose of the randomized controlled trial is to evaluate the safety and efficacy of adding magnesium sulphate to the…
- Trial name
- NCT07438366
- Testing
- Pectointercostal Plane Block (PIPB), Erector Spinae Plane Block (ESPB), Magnesium sulfate
- Volunteers
- 60 people
- Sponsor
- South Egypt Cancer Institute
Cancer Breast, Chronic Pain Syndrome
Magnesium Sulphate to Bupivicaine in Serratus Anterior Plane Block in Modified Radical Mastectomy
Modified radical mastectomy may be associated with severe post-operative pain, leading to chronic pain syndrome which usually requires optimal perioperative pain management.
- Trial name
- NCT04429893
- Testing
- magnesium sulphate, bupivicaine
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Alexandria University
Refractory Chronic Cluster Headache
Ketamine + Magnesium for Chronic Cluster Headache (KETALGIA)
Chronic cluster headache (CCH) is a rare primary headache disorder, defined by episodic attacks that occur for more than one year with no remission period or with remission periods lasting < 3 months (ICHD-3 criteria).
- Trial name
- KETALGIA (NCT04814381)
- Testing
- Ketamine + Magnesium sulfate (drug combination)
- Where
- 14 sites in France
- Volunteers
- 93 people
- Sponsor
- University Hospital, Clermont-Ferrand
Atrial Fibrillation
Magnesium Sulphate for Treatment of New Onset Atrial Fibrillation in Medical Intensive Care Unit Patient
The purpose of this study is to determine the efficacy of Magnesium sulphate for the rate and rhythm control of the new onset (within 48 hours) atrial fibrillation in the hemodynamically unstable patients, admitted in the medical…
- Trial name
- EMSAF (NCT01049464)
- Testing
- Magnesium sulphate
- Where
- Thailand
- Volunteers
- 128 people
- Sponsor
- Mahidol University
Pain, Opioid Use, Unspecified, Uncomplicated
The Effect of Magnesium Sulfate Infusion on the Quality of Recovery of Ambulatory Patients
A national survey has revealed that 80% of patients experienced pain after surgery and 86% of these patients had moderate, severe or extreme pain (1).Postoperative pain can extend recovery room stay after surgery and it is also a…
- Trial name
- NCT01433081
- Testing
- administration of magnesium sulfate
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Northwestern University
Functional Endoscopic Sinus Surgery
Comparison Between Pregabalin and Magnesium Sulfate in Hypotensive Anaesthesia
Comparison between pregabalin and magnesium sulfate in hypotensive anaethesia
- Trial name
- NCT05442931
- Testing
- Pregabalin 150mg, Magnesium Sulfate, Nitroglycerin
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Minia University
Neuromuscular Blockade
The Effect of Magnesium Sulphate on the Time Course of Rocuronium Induced Neuromuscular Block
The aim of this study is to investigate whether an optimized pre-treatment with intravenous magnesium enhances the speed of onset of a standard intubation dose of rocuronium.
- Trial name
- MagRoc (NCT00405977)
- Testing
- Physiologic saline, Magnesium sulphate
- Where
- Switzerland
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University Hospital, Geneva
Post Spinal Anesthesia Shivering
Two Doses of IV Magnesium Sulfate for Prevention of Post-Spinal Shivering
The main purpose of the study is to compare the incidence of clinically significant shivering, defined as Grade 3 or 4 on the Crossley-Mahajan shivering scale, within 60 minutes after spinal anesthesia.
- Trial name
- NCT07913828
- Testing
- Magnesium Sulfate 50 mg/kg IV, Magnesium Sulfate 30 mg/kg IV
- Where
- Egypt
- Volunteers
- 82 people
- Sponsor
- Suez Canal University
Anesthesia
Does Adding Magnesium Sulphate to Low Dose Rocuronium Affects Depth of Blockade
This study aim is to compare the effect of magnesium sulphate combined with low dose rocuronium versus standard dose rocuronium
- Trial name
- NCT04510337
- Testing
- standard rocuronium dose, Magnesium sulfate
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- National Cancer Institute, Egypt
Postoperative Pain, Obesity
Comparison of Two Magnesium Sulfate Protocols in Opioid-Free Anesthesia for Bariatric Surgery
This retrospective observational study aims to compare postoperative morphine consumption in patients undergoing bariatric surgery with opioid-free anesthesia (OFA) using two different intravenous magnesium sulfate administration…
- Conditions
- Postoperative Pain, Obesity, Bariatric Surgery, Opioid-free Anesthesia
- Trial name
- OFA-MG (NCT07077031)
- Where
- Spain
- Volunteers
- 110 people
- Sponsor
- Hospital HM Nou Delfos
Analgesia
Dexmedetomidine Versus Magnesium Sulphate Added to Bupivacaine in Infraorbital Nerve Block for Perioperative Analgesia in Paediatric Patients for Cleft Lip Surgery
Regional analgesia is considered the cornerstone for postoperative analgesia in paediatric patients. One of the most common birth defects which require surgical intervention early in life is the cleft lip.
- Trial name
- NCT05624151
- Testing
- Dexmedetomidine +Bupivacaine, Magnesium Sulfate + Bupivacaine, Bupivacaine
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Ain Shams University
Postoperative Analgesia
Magnesium and Ketamine in Postoperative Analgesia
90 female patients scheduled for cancer breast surgeries will be assigned to 2 groups, each of 45. Group (K) will receive a bolus of 0.5 mg/kg ketamine with induction of anaesthesia, followed by ketamine infusion 0.12 mg/kg/hour…
- Trial name
- NCT04111848
- Testing
- Ketamine, ketamine and magnesium
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- National Cancer Institute, Egypt
Infertility Female, Hemodynamic Instability
Lidocaine vs Magnesium Sulfate for Hemodynamic Stability During Emergence in Infertility-Related Laparoscopic Surgery"
This study is being conducted to compare two medications, intravenous lidocaine and intravenous magnesium sulfate, and their ability to keep blood pressure and heart rate stable during the period of waking up from general…
- Trial name
- LidoMagGyna (NCT07359560)
- Testing
- Lidocaine (drug), Normal Saline (Intravenous), magnesium sulfate
- Where
- Egypt
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Renal Neoplasm
Dexamethasone Versus Mg Added to Bupivacaine Used in ESPB for Perioperative Pain Control in Patients Undergoing Unilateral Nephrectomy
Aim of the study: The current study aims to compare the effect of adding dexamethasone versus magnesium sulfate to bupivacaine in ultrasound-guided erector spinae plane block on the severity of postoperative pain.
- Trial name
- NCT06501079
- Testing
- ultrasound guided Erector Spinae Plane Block using 27ml bupivacaine 0.25%
- Where
- Egypt
- Volunteers
- 78 people
- Sponsor
- National Cancer Institute, Egypt
Renal Colic
Treatment of Renal Colic in the Emergency Departement (ED).
to evaluate the analgesic effect of a standard dose of intravenous magnesium added to intramuscular diclofenac compared to intravenous lidocaine combined to intramuscular diclofenac or intramuscular diclofenac alone in patients…
- Trial name
- NCT03199924
- Testing
- Diclofenac, Magnesium Sulfate, Lidocaine
- Where
- Tunisia
- Volunteers
- 600 people
- Sponsor
- University of Monastir
Patient Satisfaction
Patient Satisfaction With Abbreviated Postpartum Magnesium Sulfate for Severe Preeclampsia
Preeclampsia is a common and potentially devastating disease that affects only pregnant or postpartum patients. It is a leading cause of maternal mortality not only worldwide, but in the United States as well.
- Trial name
- NCT05789381
- Testing
- Magnesium sulfate
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Chicago
Perinatal Asphyxia , Moderate to Severe HIE
Magnesium Sulphate in Perinatal Asphyxia
Magnesium sulphate has been shown to be neuroprotective. The investigators hypothesize that magnesium sulphate infusion given to babies with perinatal asphyxia should improve outcome in the immediate neonatal period.
- Trial name
- Magsulf (NCT00553072)
- Testing
- Magnesium sulphate, Normal saline
- Where
- India
- Volunteers
- 40 people
- Sponsor
- Sheri Kashmir Institute of Medical Sciences
Chemotherapeutic Agent Toxicity, Colorectal Cancer
Calcium Gluconate and Magnesium Sulfate in Preventing Neurotoxicity in Patients With Colon Cancer or Rectal Cancer Receiving Oxaliplatin-Based Combination Chemotherapy
RATIONALE: Chemoprotective drugs, such as calcium gluconate and magnesium sulfate, may prevent neurotoxicity caused by oxaliplatin.
- Conditions
- Chemotherapeutic Agent Toxicity, Colorectal Cancer, Neuropathy, Neurotoxicity
- Trial name
- NCT01099449
- Testing
- calcium gluconate, magnesium sulfate, oxaliplatin
- Where
- 405 sites in United States, Puerto Rico
- Volunteers
- 362 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Hemodynamic Response to Laryngoscopy and Tracheal Intubation
Intravenous Magnesium Sulphate Versus Lignocaine for Attenuating Hemodynamic Responses to Laryngoscopy and Endotracheal Intubation
This study will compare intravenous magnesium sulfate with intravenous lidocaine for reducing the cardiovascular response to endotracheal intubation in adult patients undergoing general anesthesia.
- Trial name
- NCT07793955
- Testing
- Magnesium Sulphate infusion
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Lady Reading Hospital, Pakistan