Clinical trials: Magnesium Sulphate
Prostatectomy
Magnesium Sulfate as an Adjunctive Analgesic in Prostate Surgery
The purpose of this clinical trial is to determine if receiving magnesium sulfate as an adjunctive analgesic for prostate surgery is effective in reducing pain.
- Trial name
- NCT06477133
- Testing
- Magnesium sulfate
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- NYU Langone Health
Preeclampsia With Severe Features
Use of Cheetah® Cardiac Monitoring System to Guide Discontinuation of Magnesium Sulfate in Women With Severe Preeclampsia
This is a single site pilot randomized, controlled, trial randomizing patients with PE with severe features to one of 2 groups: 24 hours of postpartum magnesium sulfate (current arbitrary standard of care) Using the Cheetah®…
- Trial name
- NCT04474704
- Testing
- Cheetah® non-invasive cardiac monitoring system, Standard of care
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Brain Tumor
Dexmedetomidine Versus Magnesium Sulphate in Patients Undergoing Craniotomy for Deeply Settled Intracranial Tumours
An intracranial tumor, is an abnormal mass of tissue in which cells grow and multiply uncontrollably, seemingly unchecked by the mechanisms that control normal cells.
- Trial name
- NCT05743725
- Testing
- Dexmedetomidine, Magnesium sulfate
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Assiut University
Colonic Adenoma, Bowel Preparation
Efficacy of Split-dose of Oral MMS for Bowel Preparation in Elderly Patients
Adequate bowel preparation is critical for successful colonoscopy and a large volume of PEG was required for bowel preparation in patients undergoing colonoscopy.
- Trial name
- NCT04948567
- Testing
- split-dose of Magnesium Sulfate solution, split-dose of PEG
- Where
- 2 sites in China
- Volunteers
- 1,174 people
- Sponsor
- Air Force Military Medical University, China
Pediatric Burns
Magnesium Sulfate in Pediatric Burn Dressing Changes
Prospective feasibility trial utilizing adjuvant magnesium sulfate for analgesia/sedation during pediatric sedated burn dressing changes, which is ultimately hypothesized to decrease ketamine and/or sedative requirements.
- Trial name
- NCT07126795
- Testing
- magnesium sulfate, Normal Saline (0.9% NaCl)
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Hennepin Healthcare Research Institute
Infant, Newborn, Infant, Low Birth Weight
In Utero Magnesium Sulfate Exposure: Effects on Extremely-Low-Birth-Weight Infants
This study examined the effect of magnesium sulfate (MgSO4) exposure on adverse outcome in extremely low birth weight (ELBW) infants.
- Conditions
- Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age, Infant, Premature
- Trial name
- MgSO4 (NCT01203501)
- Where
- 15 sites in United States
- Volunteers
- 1,339 people, healthy volunteers welcome
- Sponsor
- NICHD Neonatal Research Network
Postpartum Depression
The Effect of Peripartum Magnesium Sulfate Use on the Occurrence of Postpartum Depression
This is an observational study that will be conducted on pregnant women under vaginal delivery or cesarean section. The magnesium sulfate will be given to appropriate participants with a protocol that obstetrician are already…
- Trial name
- NCT05751746
- Testing
- Magnesium sulfate
- Where
- South Korea
- Volunteers
- 108 people
- Sponsor
- Seoul National University Bundang Hospital
Postoperative Pain
Analgesic Efficacy of the Erector Spinae Plane Block Using Bupivacaine Versus Bupivacaine/Magnesium Sulphate in Patients Undergoing Lumbar Spine Surgery
Introduction: Severe postoperative pain following spine surgery is a significant cause of morbidity, extended length of facility stay, and marked opioid usage The analgesic regime for postoperative pain usually includes…
- Trial name
- NCT04433624
- Testing
- Group (B)
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Beni-Suef University
Head Pain
Intravenous Magnesium Sulfate Vs Placebo to Treat Non -Traumatic Acute Headaches in the Emergency Department
Intravenous Magnesium Sulfate Vs Placebo to Treat Non -Traumatic Acute Headaches in the Emergency Department
- Trial name
- NCT05325580
- Testing
- Magnesium sulfate
- Where
- Tunisia
- Volunteers
- 424 people
- Sponsor
- University of Monastir
Hand, Foot and Mouth Disease
Magnesium Sulphate for Severe Hand, Foot and Mouth Disease in Vietnam
Hand foot and mouth disease (HFMD) is a common infectious disease caused by a number of different viruses - a small proportion of children infected with a particular type of enterovirus (EV71) develop neurological and systemic…
- Trial name
- NCT01940250
- Testing
- Magnesium Sulphate, Sterile water
- Where
- 2 sites in Vietnam
- Volunteers
- 26 people
- Sponsor
- Oxford University Clinical Research Unit, Vietnam
Pre-Eclampsia
Impact of Body Mass Index on Serum Maternal and Fetal Magnesium Level
Magnesium sulphate is an inorganic salt with multiple therapeutic applications in medicine it has been widely utilized and studied on a diverse set of conditions such as asthma, cardiac arrhythmia and stroke.
- Trial name
- NCT03928691
- Testing
- Magnesium Sulfate
- Where
- Egypt
- Volunteers
- 400 people
- Sponsor
- Assiut University
Easy of Laryngoscopy Manipulation, Vocal Cord Position or Movement
Intubating Condition After Magnesium Pre-treatment
Magnesium had an inhibitory effect on neuromuscular transmission and caused a decrease in muscle fiber membrane excitability. It reduces the amount of acetylcholine that is released at the motor nerve terminal by decreasing the…
- Conditions
- Easy of Laryngoscopy Manipulation, Vocal Cord Position or Movement, Patient Reaction to Intubation and Cuff Inflation, Mean Arterial Pressure
- Trial name
- NCT01153256
- Testing
- magnesium sulphate, normal saline
- Where
- South Korea
- Volunteers
- 168 people
- Sponsor
- Seoul National University Bundang Hospital
Intracranial Pressure Control in Pre-eclampsia
Dexamedtomidine in Control of Intracranial Pressure in Preeclampsia
The present study is designed to evaluate the differences in the effect of Mg sulphate alone and dexmedetomidine as an adjuvant to Mg sulphate on intracranial pressure when administered intravenously in cases of pre-eclampsia
- Trial name
- NCT05119101
- Testing
- Dexamedotomidine added to Magnesium sulfate, Magnesium sulfate
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Assiut University
Fetal Neuroprotection
Magnesium Sulfate (MgSO4) and Fetal Heart Rate (FHR) in Case of Prematurity
Type of study: prospective descriptive monocentric study Population: 2 groups: -Exposed group: pregnant patient between 24AW+0day and 32AW+0day receiving magnesium sulfate for fetal neuroprotection in the doubt of premature…
- Trial name
- NCT03956121
- Testing
- injection of magnesium sulfate
- Where
- France
- Volunteers
- 57 people
- Sponsor
- CHU de Reims
Operation
Spinal Anesthesia Magnesium Infusion
The aim of this study was to investigate the effect of i.v. infusion of magnesium sulphate during spinal anesthesia on duration of spinal block and postoperative pain.
- Trial name
- NCT02011152
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Karadeniz Technical University
Anesthesia, Pain, Postoperative
Effects Of Additional MgSO4 30 Mg/KgBW Intravenous and Ketorolac
This study aims to compare two groups of post-orthopedic patients who received a standard regimen, namely ketorolac 30mg, to the second group, which was given the standard regimen and adjuvant magnesium sulfate 30mg/kgBW 1 hour…
- Conditions
- Anesthesia, Pain, Postoperative, Surgery, Opioid Use
- Trial name
- NCT05609955
- Testing
- MgSO4
- Where
- Indonesia
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Neuropathic Pain
Ketamine and Neuropathic Pain
The primary outcome is to compare the analgesic efficacy of intravenous ketamine treatment to that of a placebo in patients with refractory neuropathic pain. The secondary outcomes are: 1.
- Trial name
- KETAPAIN (NCT02467517)
- Testing
- Ketamine, Magnesium Sulfate
- Where
- France
- Volunteers
- 22 people
- Sponsor
- University Hospital, Clermont-Ferrand
Anesthesia
Effect of mgso4 on Oxygenation and Lung Mechanics in Morbidly Obese Patients During Bariatric Surgery
The purpose of this trial is to study the effect of mgso4 infusion on oxygenation and lung mechanics in morbidly obese patients undergoing bariatric surgery
- Trial name
- NCT04769440
- Testing
- mg sulphate
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Duloxetine, Magnesium Sulphate
Pain Relieving Potentials of Combination of Oral Duloxetine and Intravenous Magnesium Sulphate in Post Mastectomy Pain
This study aims to evaluate the effect of combined duloxetine and IV Magnesium sulphate to decrease acute and chronic post mastectomy pain.
- Conditions
- Duloxetine, Magnesium Sulphate, Post-mastectomy Pain Syndrome
- Trial name
- NCT06087211
- Testing
- Magnesium sulphate and Duloxetine, Duloxetine
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- National Cancer Institute, Egypt
Hypoxic Ischemic Encephalopathy (HIE)
Neonates With Hypoxic Ischemic Encephalopathy (HIE)
Assessment of the potential neuroprotective effect of magnesium sulphate and caffeine in treating asphyxiated newborns and improvement of the neurological outcome of Hypoxic Ischemic Encephalopathy in Assiut university hospital…
- Trial name
- NCT06694545
- Volunteers
- 72 people
- Sponsor
- Assiut University