Clinical trials: Magnesium Sulphate
Screening
Preoperative Nebulized Dexmedetomidine Versus Nebulized Magnesium Sulphate in Reducing Emergence Agitation in FESS
Emergence agitation after sinus surgery is a common postoperative complication characterized by confusion, disorientation, and potentially violent behavior as a patient wakes from general anesthesia.This study compare the effect…
- Trial name
- NCT07677917
- Testing
- Dexmedetomidine, Magnesium sulfate
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Pain
The Effect of Adding Magnesium Sulfate to Standard Epidural and Interscalene Block in Treatment of Patients With Chronic Pain
Regional anesthesia is a safe, inexpensive technique, with the advantage of prolonged pain relief. In the pain clinic the investigators perform different injections as the standard treatment for chronic pain based on the…
- Trial name
- NCT01918514
- Testing
- Adding Magnesium Sulfate to the standard epidural and interscalene blocks for chronic pain
- Where
- United States
- Sponsor
- State University of New York - Upstate Medical University
Mental Disorder
Dexmedetomidine and Magnesium Sulfate in the Reduction Cognitive Dysfunction in Geriatrics
Magnesium sulfate is considered a neuroprotective drug and has been studied in various applications. Recently, it has drawn the attention of anesthesiologists, resulting in numerous publications about its role in anesthesiology.
- Trial name
- NCT06702488
- Testing
- dexmedetomidine
- Where
- Egypt
- Volunteers
- 58 people
- Sponsor
- Fayoum University
Magnesium Sulfate Causing Adverse Effects in Therapeutic Use, Neuromuscular Blockade
Effect of Magnesium on Dose of Rocuronium for Deep Neuromuscular Blockade
It is well known that magnesium enhances the effect of neuromuscular blocking agents such as rocuronium. However, it is not known how much magnesium can reduce neuromuscular blocking agents in maintaining deep neuromuscular…
- Trial name
- NCT04013243
- Testing
- Magnesium Sulfate
- Where
- South Korea
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
Postoperative Pain
Analgesic Potentials of Preoperative Pregabalin,Magnesium Sulphate and Their Combination in Acute Post-thoracotomy Pain
This study evaluates the effect of giving preoperative adjuvant drug as pregabalin or magnesium sulphate or a combination of both drugs to decrease postoperative morphine consumption and pain intensity in the first 24 hours in…
- Trial name
- NCT02678117
- Testing
- Pregabalin & Magnesium sulphate
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- National Cancer Institute, Egypt
Organophosphate Poisoning
Magnesium Sulphate With Atropine and Pralidoxime vs Standard Therapy Alone in Acute Organophosphate Poisoning
Pakistan, being a developing country, is one of the regions with the most cases of organophosphate (OP) poisoning/toxicity. MgSO4 is one of the most promising adjunctive treatments that needs to be tested.
- Trial name
- NCT07777835
- Testing
- Atropine plus pralidoxime, Atropine and pralidoxime with adjunctive MgSO4
- Where
- Pakistan
- Volunteers
- 38 people
- Sponsor
- Muhammad Aamir Latif
Hypoxic Ischemic Encephalopathy (HIE)
Neonates With Hypoxic Ischemic Encephalopathy (HIE)
Assessment of the potential neuroprotective effect of magnesium sulphate and caffeine in treating asphyxiated newborns and improvement of the neurological outcome of Hypoxic Ischemic Encephalopathy in Assiut university hospital…
- Trial name
- NCT06694545
- Volunteers
- 72 people
- Sponsor
- Assiut University
Chronic Pain
The Effectiveness of Continuous Ketamine Infusion (KONTINUE)
There are different treatment for chronic pain. One possible treatment is intravenous infusions of ketamine.
- Trial name
- KONTINUE (NCT06131970)
- Where
- Monaco
- Volunteers
- 80 people
- Sponsor
- Centre Hospitalier Princesse Grace
Vaginal Delivery, Perineal Swelling
Cold Magnesium Sulfate Solution for Perineal Swelling Following Vaginal Delivery
The purpose of this study is to compare the impact of treatment with cooled magnesium sulfate and cold water-soaked pads on perineal pain and swelling following vaginal delivery.
- Conditions
- Vaginal Delivery, Perineal Swelling, Perineal Pain
- Trial name
- MgSo4 (NCT02024256)
- Testing
- Cold pads soaked in Magnesium sulfate solution, Cold pads soaked in water
- Where
- 2 sites in Israel
- Volunteers
- 206 people
- Sponsor
- HaEmek Medical Center, Israel
Preeclampsia and Eclampsia
Springfusor for Administration of Magnesium Sulphate in Preeclampsia and Eclampsia
Magnesium Sulphate is the drug of choice for prevention and treatment of seizures in preeclampsia and eclampsia. It is administered parenterally by intravenous (IV) and or intramuscular (IM) routes.
- Trial name
- NCT03549767
- Testing
- Springfusor, Standard of care
- Where
- Uganda
- Volunteers
- 241 people
- Sponsor
- Makerere University
Post Partum Severe Preeclampsia
Magnesium Sulfate During the Postpartum in Women With Severe Preeclampsia
There is no evidence that patients receiving magnesium sulfate before birth are required to maintain the drug for 24 hours. Therefore the investigators will have a randomized clinical study in patients with severe preeclampsia…
- Trial name
- MAG-PIP (NCT02307201)
- Testing
- Magnesium Sulfate
- Where
- 9 sites in Dominican Republic, Ecuador and 3 more
- Volunteers
- 1,114 people, healthy volunteers welcome
- Sponsor
- Complejo Hospitalario Dr. Arnulfo Arias Madrid
Anesthesia, Pain
Lidocaine Compared to Magnesium Sulfate to Prolong Spinal Anesthesia: Non-inferiority Randomized Clinical Trial
This study evaluates the addition of continuous infusion of lidocaine or continuous infusion of magnesium sufate in the duration of spinal anesthesia.
- Trial name
- NCT03725228
- Testing
- Magnesium Sulfate, Lidocaine
- Where
- Brazil
- Volunteers
- 44 people
- Sponsor
- Brasilia University Hospital
Myofacial Pain, Trigger Points, Myofascial
Comparison Between Botox and Magnesium Sulfate Effect in Treatment of Myofascial Pain Trigger Points Within the Masseter Muscle
The goal of this randomized clinical trial is to compare the effectiveness of Botulinum toxin type A, magnesium sulfate and saline injections in treatment of the masseter muscle trigger points, in patients between 16 - 50 years…
- Trial name
- MPS MTrPs BTA (NCT06676475)
- Testing
- MgSO4, BOTOX-A
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Misr University for Science and Technology
Patient Satisfaction
Patient Satisfaction With Abbreviated Postpartum Magnesium Sulfate for Severe Preeclampsia
Preeclampsia is a common and potentially devastating disease that affects only pregnant or postpartum patients. It is a leading cause of maternal mortality not only worldwide, but in the United States as well.
- Trial name
- NCT05789381
- Testing
- Magnesium sulfate
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Chicago
Preemptive Analgesia, Dexmedetomidine
Dexmedetomidine, Ketamine and Magnesium Sulphate in Caudal Block for Hypospadias Repair
Caudal epidural block is a rapid, reliable, and safe technique that can be used with general anesthesia for intraoperative and postoperative analgesia in pediatric patients Ketamine is a selective antagonist of…
- Conditions
- Preemptive Analgesia, Dexmedetomidine, Ketamine, Magnesium Sulphate
- Trial name
- NCT05837000
- Testing
- Dexmedetomidine, Ketamine, Magnesium sulphate
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Kafrelsheikh University
Threatened Preterm Labor
Nifedipine Plus Magnesium Sulfate Versus Magnesium Sulfate for Very Early Preterm Tocolysifs
Objective: This trial is designed to compare between the effectiveness of nifedipine plus magnesium sulfate (MgSO4) and MgSO4 alone for tocolysis in women with threatened preterm labor.
- Trial name
- ASTOS1 (NCT05345132)
- Testing
- Nifedipine 20 Mg, Magnesium sulfate
- Where
- Egypt
- Volunteers
- 264 people
- Sponsor
- Assiut University
Asthma
Lung Function of Asthmatic Children by Nebulized MgSO4
Asthma is a common chronic respiratory illness which results in frequent wheezing, cough,reduced quality of life. Standard treatment for asthma attack includes oxygen therapy, β2-agonists (e.g.
- Trial name
- NCT01799109
- Testing
- Magnesium Sulfate & albuterol, albuterol, magnesium
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Chongqing Medical University
Magnesium Sulfate Pharmacokinetics and Pharmacodynamics
PK/PD Modeling of Magnesium in the Mother and Neonate
Determine significant correlations between maternal serum magnesium levels, and maternal and neonatal outcomes.
- Trial name
- NCT01709630
- Testing
- Magnesium sulfate infusion
- Where
- United States
- Volunteers
- 151 people
- Sponsor
- Stanford University
Acute Pain Due to Trauma
Magnesium-sulfate as Adjuvant in Prehospital Femoral Nerve Block for Patient With Diaphysial Femoral Fracture.
Prehospital management of traumatic pain is commonly based on morphine while loco-regional analgesia techniques, especially the femoral nerve block (FNB), can be safely and efficiently used.
- Trial name
- NCT03597945
- Testing
- lidocaine with epinephrine, normal saline, Magnesium sulfate
- Volunteers
- 48 people
- Sponsor
- Faculty of Medicine, Sousse
Pain, Postoperative, Pain, Acute
A Study of the Effects of Intravenous Magnesium Sulphate on Anaesthesia and Analgesia in Elective General Surgery Patients
The aim of this double-blind randomized study will be to evaluate the effect an intravenous infusion of magnesium has on recovery outcomes after elective laparoscopic cholecystectomy
- Conditions
- Pain, Postoperative, Pain, Acute, Pain, Nociceptive, Analgesia
- Trial name
- NCT05598307
- Testing
- magnesium bolus followed by normal saline infusion, magnesium bolus followed by magnesium infusion, normal saline bolus followed by normal saline infusion
- Where
- Greece
- Volunteers
- 90 people
- Sponsor
- Aretaieion University Hospital