Clinical trials: Magnesium Sulphate
Postoperative Pain
A Comparative Study of Intrathecal Magnesium Sulphate & Midazolam With Epidural Ropivacaine for Caesarean Patients
This study compares whether addition of Magnesium or Midazolam intrathecally to epidurally administered isobaric Ropivacaine improves the quality of blockade, haemodynamics and duration of analgesia post-operatively.
- Trial name
- NCT02619799
- Testing
- intrathecal magnesium sulphate,, Intrathecal midazolam
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Rangaraya Medical College
Colorectal Cancer
Efficacy and Tolerability of Suprep With and Without Simethicone for Routine Colonoscopy for Colorectal Cancer Screening
The purpose of this study is to investigate Suprep bowel preparation, with and without the anti-gas medication simethicone, in terms of efficacy and patient tolerability in the preparation of patients undergoing routine…
- Trial name
- NCT02523911
- Testing
- Simethicone, sodium sulfate/potassium sulfate/magnesium sulfate solution
- Where
- 2 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- MercyOne Des Moines Medical Center
Hemodynamics Instability, Pain After Surgery
Effect of Magnesium Sulfate on Hemodynamics on Laparoscopic Cholecystectomy Patients
The goal of this triple blinded randomized control trial is to compare the effect of magnesium sulphate on the hemodynamic response during pneumoperitoneum creation, along with its impact on postoperative pain, opioid…
- Conditions
- Hemodynamics Instability, Pain After Surgery, PONV in Laparoscopic Cholocystectomies
- Trial name
- NCT07079514
- Testing
- Magnesium
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ziauddin University
Magnesium, Intraoperative Analgesia
Magnesium Sulfate as an Adjuvant to Propofol During Consious Sedation in Colonoscopy
Colonoscopy is one of the most commonly performed outpatient procedures throughout the world as a screening, diagnostic, and therapeutic tool to evaluate the large intestine from the distal rectum to the cecum.Propofol is the…
- Trial name
- NCT06131905
- Testing
- Magnesium Sulfate, Propofol
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Assiut University
Arrhythmias
Antiarrhythmic and Cardioprotective Effects of Atorvastatin Versus Magnesium Sulfate in Cardiac Valve Replacement Surgery
This study aims to compare the antiarrhythmic and cardioprotective effects of Atorvastatin versus Magnesium Sulfate after Cardiac valve Replacement Surgery
- Trial name
- NCT03289429
- Testing
- Atorvastatin, Magnesium Sulfate
- Where
- Egypt
- Volunteers
- 96 people
- Sponsor
- Assiut University
Preeclampsia
A Trial Comparing Treatment With the Springfusor Infusion Pump to the IV Magnesium Sulfate Regimen
The trial will test the equivalence of a repeat bolus protocol of magnesium sulfate administered by the Springfusor® controlled pump to a continuous intravenous regimen.
- Trial name
- NCT02091401
- Testing
- Springfusor infusion pump, IV administration, Magnesium Sulfate
- Where
- 2 sites in Egypt
- Volunteers
- 200 people
- Sponsor
- Gynuity Health Projects
Anesthesia and Analgesia, Magnesium Sulfate
Magnesium Sulfate in Bariatric Surgery
Weight loss surgery, also known as bariatric surgery, has been around since the 1950s and since its inception has been shown to successfully achieve significant and sustainable weight loss in a large number of patients who…
- Conditions
- Anesthesia and Analgesia, Magnesium Sulfate, Bariatric Surgery Candidate
- Trial name
- MgSObs (NCT05843812)
- Testing
- Magnesium Sulfate 10 MG/ML
- Where
- Mexico
- Volunteers
- 104 people
- Sponsor
- Instituto Mexicano del Seguro Social
Traumatic Brain Injuries
Anti-inflammatory Effect of MgSO₄ in Patients With Moderate Traumatic Brain Injury by Measurming Nucleotide-binding Oligomerization Domain-Like Receptor Pyrin Domain-containing 3 (NLRP3) Inflammasome-a Multiprotein Complex
The primary objective of this study is to evaluate the biochemical efficacy of Magnesium Sulfate (MgSO₄) as an anti-inflammatory therapeutic agent in patients suffering from moderate traumatic brain injury (TBI) at Assiut…
- Trial name
- NCT07763665
- Testing
- Magnesium sulfate (MgSO4), Normal Saline
- Volunteers
- 64 people
- Sponsor
- Assiut University
Hemorrhage
Controlled Hypotension During Functional Endoscopic Sinus Surgery
It is very important to decrease the bleeding during functional endoscopic sinus surgery (FESS) in order to increase the visibility of the surgical site.
- Trial name
- NCT01956981
- Testing
- Magnesium Sulfate, Dexmedetomidine
- Volunteers
- 60 people
- Sponsor
- TC Erciyes University
Postoperative Analgesia
Ketamine and Magnesium in Erector Spinae Plane Block
In this study, it will aimed to evaluate the effect of magnesium sulfate and ketamine HCl added to local anesthetic on postoperative pain management in the ultrasound-guided erector spina plane (ESP) block in patients will…
- Trial name
- NCT05855798
- Testing
- Bupivacain, Magnesium sulfate, Ketamine Hydrochloride
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Dexmedetomidine, Magnesium Sulfate
Intraperitoneal Dexmedetomidine Versus Magnesium as Adjuvants to Bupivacaine in Laparoscopic Cholecystectomy
Although both dexmedetomidine and magnesium sulphate have been individually evaluated as adjuvants to local anesthetics, direct comparisons between the two agents in intraperitoneal instillation during laparoscopic…
- Conditions
- Dexmedetomidine, Magnesium Sulfate, Laparoscopic Cholecystectomy
- Trial name
- NCT07693621
- Testing
- Bupivacaine 100 mg + dexmedetomidine 1 µg/kg, Bupivacaine 100 mg + magnesium sulphate 50 mg/kg
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Alexandria University
Cough
Effect of Magnesium on Remifentanil Induced Cough
The hypothesis of this study is that Magnesium sulfate pretreatment (50mg/kg) will reduce the incidence of cough and chest wall rigidity caused by remifentanil administration.
- Trial name
- NCT05237791
- Testing
- Magnesium sulfate
- Volunteers
- 78 people
- Sponsor
- Seoul National University Bundang Hospital
Renal Neoplasm
Dexamethasone Versus Mg Added to Bupivacaine Used in ESPB for Perioperative Pain Control in Patients Undergoing Unilateral Nephrectomy
Aim of the study: The current study aims to compare the effect of adding dexamethasone versus magnesium sulfate to bupivacaine in ultrasound-guided erector spinae plane block on the severity of postoperative pain.
- Trial name
- NCT06501079
- Testing
- ultrasound guided Erector Spinae Plane Block using 27ml bupivacaine 0.25%
- Where
- Egypt
- Volunteers
- 78 people
- Sponsor
- National Cancer Institute, Egypt
Pregnancy, Preeclampsia
Abbreviated MgSO4 Therapy in Post-partum Preeclampsia
Magnesium sulfate is used for seizure prophylaxis in pregnancies complicated by preeclampsia. There is debate as to how long to continue this therapy after delivery of the pregnancy.
- Trial name
- NCT00344058
- Testing
- abbreviation of magnesium sulfate therapy (12 hours versus the traditional 24 hours after delivery)
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Case Western Reserve University
Trigger Point Pain, Myofascial
IONTOPHORESIS Versus Ultrasound in Mechanical Neck Pain
to investigate the effects of Magnesium Sulphate Iontophoresis versus High Power Pain Threshold Ultrasound on pain, function and range of motion on active MTrPs found in the upper trapezius.
- Trial name
- NCT05474898
- Testing
- Magnesium Sulphate Iontophoresis +conventional therapy, High- Power Pain Threshold Ultrasound +conventional therapy, conventional theapy
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Cairo University
Chemotherapeutic Agent Toxicity, Colorectal Cancer
Calcium Gluconate and Magnesium Sulfate in Preventing Neurotoxicity in Patients With Colon Cancer or Rectal Cancer Receiving Oxaliplatin-Based Combination Chemotherapy
RATIONALE: Chemoprotective drugs, such as calcium gluconate and magnesium sulfate, may prevent neurotoxicity caused by oxaliplatin.
- Conditions
- Chemotherapeutic Agent Toxicity, Colorectal Cancer, Neuropathy, Neurotoxicity
- Trial name
- NCT01099449
- Testing
- calcium gluconate, magnesium sulfate, oxaliplatin
- Where
- 405 sites in United States, Puerto Rico
- Volunteers
- 362 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Sickle Cell Disease
Intravenous Magnesium for Sickle Cell Vasoocclusive Crisis
The purpose of this study is to determine the safety and efficacy of intravenous magnesium in shortening the duration of a pain crisis and to determine the health-related quality of life and short term outcomes of children…
- Trial name
- MAGiC (NCT01197417)
- Testing
- Intravenous Magnesium Sulfate
- Where
- 8 sites in United States
- Volunteers
- 208 people
- Sponsor
- Medical College of Wisconsin
Pain Score Reduction
Magnesium Sulfate in Addition to Bupivacaine in Ultrasound-guided Transmuscular Quadratus Lumborum Block for Post-Operative Analgesia After Total Hip Arthroplasty
The aim of this clinical trial is to evaluate the efficacy of adding magnesium sulfate to bupivacaine in ultrasound-guided transmuscular quadratus lumborum block for postoperative analgesia in adult patients underdoing hip…
- Trial name
- Mgso4 (NCT06956950)
- Testing
- Bupivacaine + Magnesium sulfate, Bupivacaine + saline
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Tanta University
Cholecystectomy
Magnesium Sulfate Versus Dexmedetomidine on Anesthesia Awakening.
Magnesium sulfate (MS) and dexmedetomidine have already demonstrated the ability to reduce intra and postoperative consumption of anesthetics and analgesics, among others advantages, such as blood pressure control and…
- Trial name
- NCT04300985
- Testing
- Dexmedetomidine, Magnesium Sulfate
- Where
- Brazil
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Lumbar Disc Herniation, Emergence Agitation
Magnesium Sulfate for Prevention of Emergence Agitation in Lumbar Disc Surgery
In this retrospective study, the effect of intraoperative magnesium sulfate infusion on the incidence of postoperative emergence agitation was evaluated in adult patients who underwent elective lumbar microdiscectomy under…
- Conditions
- Lumbar Disc Herniation, Emergence Agitation, Magnesium Sulfate
- Trial name
- NCT07139847
- Testing
- Magnesium Sulfate Infusion, 0.9% Saline Infusion
- Volunteers
- 70 people
- Sponsor
- Ondokuz Mayıs University