Clinical trials: Magnesium Sulphate
Post-operative Pain, Total Hip Arthroplasty (THA)
Ultrasound Guided Lumbar Erector Spinae Block Using Bupivacaine - Magnesium Sulphate Versus Bupivacaine - Dexamethasone in Total Hip Replacement Surgery
The current study was done to evaluate the effect of adding dexamethasone and magnesium sulfate to bupivacaine as adjuvants in an ultrasound-guided erector spinae block for patients undergoing total hip arthroplasty (THA), and to…
- Conditions
- Post-operative Pain, Total Hip Arthroplasty (THA), Erector Spinae Plane Block
- Trial name
- NCT07418671
- Testing
- Bupivacaine-Magnesium Sulphate, Bupivacaine-Dexamethasone, Bupivacaine-Saline
- Where
- Egypt
- Volunteers
- 66 people
- Sponsor
- Ain Shams University
Brain Injuries, Cerebral Palsy
Magnesium Sulfate to Prevent Brain Injury in Premature Infants
Premature infants are at risk for acute brain injuries and long-term developmental problems such as cerebral palsy (CP). Research suggests that high levels of magnesium at and around the time of birth may decrease the risk of…
- Trial name
- NCT00065949
- Testing
- magnesium sulfate
- Where
- United States
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Asthma, Chronic Obstructive Pulmonary Disease
Study of the Metabolism of Two Magnesium Supplements in Healthy Volunteers
The present study is part of a project titled 'Magnesium in asthma and chronic obstructive pulmonary disease'. The hypothesis of the main project is that daily magnesium supplement will benefit patients with asthma and chronic…
- Trial name
- NCT01113138
- Testing
- Mablet (Magnesium-supplement), Magnesium Sulfate
- Where
- Denmark
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Modified Radical Mastectomy
Comparison of Mean Duration of Analgesia Following the Administration of Bupivacaine With and Without Magnesium Sulphate in Ultrasound Guided Erector Spinae Plane Block in Modified Radical Mastectomy Patients
To compare mean duration of postoperative analgesia following the administration of bupivacaine with and without magnesium sulphate in erector spinae plane block in modified radical mastectomy patients.
- Trial name
- NCT07460115
- Testing
- Group B (bupivacaine), Bupivacaine plus magnesium sulfate
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Gulab Devi Hospital
Postoperative Pain Management
Magnesium Sulphate in Oblique Subcostal TAP Block
The aim of this study is to evaluate the effect of adding different doses of MgSO4 to bupivacaine via OSCTAB block on postoperative pain control for 24 hours in patients scheduled for LC.
- Trial name
- NCT06148168
- Testing
- Bupivacaine plus normal saline, Bupivacaine plus normal saline containing MgSO4
- Volunteers
- 72 people
- Sponsor
- Assiut University
Acute Headache, Migraine
High- vs Standard-Dose Intravenous Magnesium for Acute Headache
Headache is one of the most common reasons for consultation in emergency departments and represents a significant cause of disability, particularly in patients with migraine and other primary headache disorders.
- Conditions
- Acute Headache, Migraine, Tension-type Headache, Cluster Headache
- Trial name
- MAGHEAD (NCT07779486)
- Testing
- Magnesium Sulfate 2 grams, Magnesium Sulfate 4 G, Paracetamol 1 g
- Where
- Tunisia
- Volunteers
- 300 people
- Sponsor
- University of Monastir
Total Hip Replacement
Intrathecal Magnesium and Postoperative Analgesia
Magnesium is implicated in the activation of NMDA receptors by amino-excitatory acids in the central nervous system [1]. Magnesium deficiency is associated to an increased activation of these receptors, and to an increased…
- Trial name
- NCT00560092
- Testing
- intrathecal magnesium sulfate
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Clermont-Ferrand
Trauma and Emergency Care
Early Intravenous Magnesium Sulfate and Its Impact on Cerebral Vasospasm in Traumatic Subarachnoid Hemorrhage
Subarachnoid hemorrhage (SAH) is a clinical phenomenon caused by the abrupt rupture and bleeding of blood vessels at the surface or base of the brain, which can occur for a number of reasons.
- Trial name
- NCT07252505
- Testing
- Magnesium Sulfate 10 MG/ML
- Volunteers
- 50 people
- Sponsor
- Assiut University
Cesarean Section
Dexmedetomidine Versus Magnesium Sulphate for Caesarean Delivery
Regional anesthesia has become more popular in cesarean deliveries because most of the parturients prefer being awake during the birth process. In addition, regional anesthesia may be a safer method than general.
- Trial name
- NCT03067896
- Testing
- Bupivacaine, Dexmedetomidine, Magnesium Sulfate
- Where
- Egypt
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Assiut University
Magnesium Sulfate - PPHN
Treatment of Persistent Pulmonary Hypertension in Neonates With Nebulized Magnesium Sulfate
we conducted this study to compare between effect of nebulized and intravenous magnesium sulfate (MgSO₄) for better treatment of persistent pulmonary hypertension of neonates with less side effects.
- Trial name
- PPHN (NCT06603766)
- Testing
- IV Magnesium Sulfate, Inhalational magnesium sulfate
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Benha University
Gynecologic Disease
Magnesium Sulfate; Postoperative Nausea and Vomiting; Laparoscopic Surgery
Postoperative nausea and vomiting (PONV) is commonly accompanied in patients undergoing surgery under general anesthesia. The patients undergoing laparoscopic gynecologic surgery have multiple risk factors for developing PONV…
- Trial name
- NCT03541915
- Testing
- Mg (magnesium sulfate), Control (saline)
- Volunteers
- 90 people
- Sponsor
- Gangnam Severance Hospital
Arthritis Knee, Magnesium Sulfate
Magnesium and Postoperative Pain
With ongoing advancements in healthcare leading to prolonged life expectancy, orthopedic surgeries are increasingly performed in elderly patients.
- Conditions
- Arthritis Knee, Magnesium Sulfate, Dexmedetomidine
- Trial name
- NCT03253224
- Testing
- Magnesium Sulfate, Normal saline
- Where
- South Korea
- Volunteers
- 24 people
- Sponsor
- Seoul National University Hospital
Gynecologic Laparoscopic Surgery
Intrathecal Mg in Gynecologic Laparoscopic Surgeries.
The investigators aim to investigate the differences between intrathecal Bupivacaine + Mg sulfate in spinal anesthesia versus Bupivacaine on surgeon satisfaction and postoperative pain in gynecologic laparoscopic surgeries.
- Trial name
- NCT02671227
- Testing
- intrathecal Mg sulfate., intrathecal bupivacaine 15 mg.
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Assiut University
Premature Rupture of Membrane
Magnesium Sulphate in Premature Rupture of Membranes
To assess the outcome of using magnesium sulphate on fetus and women with preterm premature rupture of membranes
- Trial name
- NCT05134688
- Testing
- Magnesium sulfate
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Assiut University
Muscle Relaxation
Magnesium Sulfate Effects on Onset and Duration of Low Dose Rocuronium in Patients Undergoing Laparoscopic Cholecystectomy
This study aims to evaluate effects of magnesium sulfate on onset and duration of low dose rocuronium, intubation condition and surgical condition in patients undergoing laparoscopic cholecystectomy.
- Trial name
- NCT02669368
- Testing
- Magnesium Sulfate, Saline, Standard dose Rocuronium
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Assiut University
Thoracic Epidural Analgesia, Fracture Ribs
Thoracic Epidural Analgesia in Multiple Traumatic Fracture Ribs
This work aims at comparing the analgesic effect of Thoracic Epidural Magnesium sulfate versus Fentanyl when added as adjuvants to Bupivacaine in patients with multiple traumatic fracture ribs.
- Trial name
- NCT03595397
- Testing
- Bupivacaine, Magnesium Sulfate, Fentanyl
- Volunteers
- 60 people
- Sponsor
- Assiut University
Procedural Pain
Intravenous Magnesium Sulfate for Post-Endoscopic Symptoms After Upper Gastrointestinal Endoscopy With Biopsy
This randomized placebo-controlled clinical trial evaluated whether intravenous magnesium sulfate reduces esophageal symptoms after upper gastrointestinal endoscopy (UGIE) with biopsy in adult patients.
- Trial name
- NCT07816848
- Testing
- Magnesium sulfate (MgSO4) infusion, 0.9 % sodium chloride
- Where
- Indonesia
- Volunteers
- 60 people
- Sponsor
- Hasanuddin University
Wound Heal
Topical Agents Containing Magnesium Sulfate & Wound Healing in the Rat Model
An experimental study examining wound healing in 5 different groups on 30 rats.
- Trial name
- NCT04886882
- Testing
- Experimental drug 1, Experimental drug 2, Centella asiatica
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Anemia, Sickle Cell
MAST - Magnesium for Sickle Cell Acute Crisis in Children
The purpose of this study is to determine if intravenous magnesium sulfate treatment is effective in reducing the length of stay and pain in children with sickle cell disease suffering an acute vaso-occlusive episode.
- Trial name
- NCT00313963
- Testing
- Magnesium Sulfate, Normal Saline
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- The Hospital for Sick Children
Severe Preeclampsia
Protocols for Magnesium Sulfate Maintenance Dose in Overweight and Obese Women Diagnosed With Preeclampsia
There is still no evidence of the appropriate dose to be used. Serum magnesium sulfate concentration is not measured regularly, thus we may be using sub-therapeutic level or reaching a toxic level.Overweight and obese women have…
- Trial name
- NCT06486025
- Testing
- maintenance magnesium sulphate1g/h, maintenance magnesium sulphate2g/h
- Volunteers
- 100 people
- Sponsor
- Ain Shams University