Clinical trials: Magnesium Sulphate
Preeclampsia/Eclampsia
Low Dose Magnesium Sulphate Versus Standard Pritchard Regimen In Management Of Severe Preeclampsia/Eclampsia
Background - Preeclampsia/eclampsia, a pregnancy specific multi-systemic disease, is associated with considerable maternal and perinatal morbidity and mortality.
- Trial name
- NCT04501289
- Testing
- Low dose magnesium sulphate, Pritchard regimen
- Where
- Nigeria
- Volunteers
- 114 people
- Sponsor
- Adebayo Joshua Adeniyi
Postoperative Pain, Back Pain Lower Back Chronic
Magnesium Sulfate Infusion on Postoperative Pain in Lumbar Surgery
Effective postoperative analgesia after lumbar spine surgery (e.g., laminectomy, vertebroplasty, lumbar stabilization) is associated with faster recovery and shorter hospital stay.
- Trial name
- NCT07418580
- Testing
- Magnesium sulfate, normal saline
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Efficacy and Safety of MgSO4 as Adjuvant to Scalp Block
The Efficacy and Safety of Magnesium Sulphate Adjuvant in Scalp Block With Ropivacaine for Supratentorial Craniotomy: a Prospective, Randomized Controlled Trial
A randomized, double-blinded controlled trial was conducted to evaluate the analgesic efficacy of MgSO4 as an adjuvant to ropivacaine in scalp blocks for craniotomy, focusing on its impact on hemodynamic parameters and…
- Trial name
- NCT07075783
- Testing
- MgSO4 plus Ropivacaine, Plain Ropivacaine
- Where
- Malaysia
- Volunteers
- 24 people
- Sponsor
- Hospital Universiti Sains Malaysia
Sedation for Patients Undergoing GIT Endoscopy
Sedation in Patients Undergoing GIT Endoscopy
Comparison of propofol-nalbuphine and propofol-magnesium sulphate sedation for patients undergoing GIT endoscopy: a double-blind, randomized trial
- Trial name
- NCT05880459
- Testing
- propofol and magnesium sulphate ,propofol and nalbuphine
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Assiut University
Patients Undergoing Lumbar Fixation
Effect of Intraoperative Magnesium Sulphate on the Occurrence of Postoperative Delirium
Anaesthesia-related complications and mortality have been significantly reduced in the last years.(1) Nevertheless, anaesthesia-related side effects, such as post-operative delirium and sleep disturbances should not be…
- Trial name
- NCT05632159
- Testing
- Mg sulphate, conventional anaesthesia
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Beni-Suef University
Peripheral Perfusion, Postoperative Pain
Effects Magnesium Sulfate and Labetalol Infusion on Peripheral Perfusion and Pain in Nasal Surgeries
One of main risk of controlled hypotension during nasal surgeries is impaired perfusion. Peripheral perfusion of non-vital organs usually impaired earlier than vital organs.
- Trial name
- NCT04688203
- Testing
- Magnesium Sulfate Injection, Labetalol Injectable Solution
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Preterm Birth, Periventricular Leukomalacia
Neuroprotection by Magnesium Sulfate Given to Women at Risk of Very Preterm Birth
Magnesium is neuroprotective in neonatal animal models of acquired hypoxic-ischemic and/or inflammatory cerebral lesions. It is associated with a significant reduction of perinatal death and cerebral palsy in some observational…
- Conditions
- Preterm Birth, Periventricular Leukomalacia, Brain Ischemia, Intracranial Hemorrhages
- Trial name
- NCT00120588
- Testing
- magnesium
- Where
- France
- Volunteers
- 700 people
- Sponsor
- University Hospital, Rouen
Anesthesia
Effect of mgso4 on Oxygenation and Lung Mechanics in Morbidly Obese Patients During Bariatric Surgery
The purpose of this trial is to study the effect of mgso4 infusion on oxygenation and lung mechanics in morbidly obese patients undergoing bariatric surgery
- Trial name
- NCT04769440
- Testing
- mg sulphate
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
AKI - Acute Kidney Injury, Arrythmia
Tailored MgSO4 Supplementation to Reduce Complications in Pediatric Heart Surgery
Lay Summary This study tests two ways of measuring blood magnesium after heart surgery. Children who need heart surgery may have heart and kidney problems after surgery. The right amount of magnesium in blood reduces this risk.
- Conditions
- AKI - Acute Kidney Injury, Arrythmia, Congenital Heart Disease
- Trial name
- NCT06564376
- Testing
- total magnesium, ionized magnesium
- Where
- United States
- Volunteers
- 96 people
- Sponsor
- West Virginia University
Post Operative Pain
Evaluation of Adding Magnesium Sulfate to (Fentanyl/Bupivacaine)Bi-mixture in Caudal Block
this is a randomized controlled study ,patients will be randomly divided into 2 groups , Group A will receive caudal block using 1ml/kg Bupivacaine +0.5u/kg fentanyl, Group B will receive caudal block 50 mg magnesium sulfate…
- Trial name
- NCT06162806
- Testing
- ultrasound guided caudal epidural block using 1ml/kg of Bupivacaine 0.25% + 0.5microgram/kg of Fentanyl, ultrasound guided caudal epidural block using 50 mg of Magnesium sulfate added to(1ml/kg of Bupivacaine 0.25% + 0.5microgram/kg of Fentanyl)
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
Stroke, Ischemic Stroke
Intravenous Magnesium Sulphate in Acute Ischemic Stroke
Magnesium has a neuroprotective role so the investigators aim to evaluate the role of intravenous magnesium sulphate in improving the clinical outcomes as assessed by the NIH Stroke Scale (NIHSS) in patients with acute ischemic…
- Trial name
- NCT04412850
- Testing
- Magnesium Sulfate
- Volunteers
- 44 people
- Sponsor
- Dow University of Health Sciences
Temporomandibular Joint Disorders, Temporomandibular Sprain
Intra-articular Magnesium Sulfate for Tmj Dysfunction
mixing the magnesium sulfate with dextrose for management of tmj pain will be studied using intra-articular injection of the solution
- Trial name
- NCT03675659
- Testing
- intra-articular injection
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Cairo University
Lower Extremity Chronic Venous Ulcers, Varicose Veins Leg
Intravenous Tramadol and Magnesium Sulphate for Prevention of Shivering
The aim of this work was to compare the efficacy of intravenous (IV) tramadol versus magnesium sulphate added to 100 ml saline for prevention of shivering associated with spinal anesthesia.
- Conditions
- Lower Extremity Chronic Venous Ulcers, Varicose Veins Leg, Hernia
- Trial name
- NCT06612996
- Testing
- Tramadol, Magnesium sulphate, Saline
- Volunteers
- 180 people
- Sponsor
- Al-Azhar University
Craniotomy Surgery
Dexmedetomidine Versus Magnesium Sulfate Infusion in Craniotomy
To compare the intraoperative effects of Dexmedetomidine and Magnesium Sulfate infusion on intracranial pressure and cerebral perfusion pressure in adult patients undergoing craniotomy
- Trial name
- NCT07199595
- Testing
- Dexamedomedine, MgSO4
- Volunteers
- 60 people
- Sponsor
- Assiut University
Asthma
Nebulized Magnesium Sulfate in Children With Moderate to Severe Asthma Exacerbation
The purpose of this study is to evaluate the effectiveness of nebulized magnesium sulfate as a vehicle for albuterol in children with moderate to severe asthma exacerbation.
- Trial name
- NCT01515995
- Testing
- Nebulized magnesium sulfate
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Texas Southwestern Medical Center
Analgesia
Intraperitoneal Analgesia in Pediatric Laparoscopy
It is important to keep children undergoing laparoscopic surgery pain free with rapid return to normal activity.
- Trial name
- NCT02820610
- Testing
- Dexmedetomidine, Magnesium Sulfate, Normal saline 0.9 %
- Where
- Egypt
- Volunteers
- 97 people
- Sponsor
- Assiut University
Anesthesia Emergence Delirium, Adenotonsillar Hypertrophy
Magnesium Sulfate Versus Other Anesthesia Drugs to Reduce Agitation After Adenotonsillectomy in Pediatric Patients
Background: Adenotonsillectomy is one of the most common pediatric surgeries and is often complicated by postoperative emergence agitation (POEA), a short-lived but distressing state of confusion and restlessness after…
- Trial name
- POEA (NCT07433231)
- Testing
- Magnesium sulfate (MgSO4) infusion, Propofol bolus, Ketamine bolus
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ayfer Kaya Gök
Intraperitoneal Magnesium Sulphate in Laparoscope in Pediatrics
Intraperitoneal Magnesium Sulphate and Bupivacaine Versus Intravenous Analgesia in Laparoscopic Surgeries in Pediatrics
The investigators are going to study the analgesic efficacy of intraperitoneal instillation of a combination of Magnesium sulphate with bupivacaine versus ordinary used parenteral analgesics for pain relief after laparoscopic…
- Trial name
- NCT04651556
- Testing
- Magnesium Sulfate & bupivacaine, paracetamol & ketorolac
- Where
- Egypt
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Menoufia University
Intubation Complication
Magnesium Sulphate and Lidocaine in Hemodynamic Changes and Cortisol Levels
The sample was randomly divided into 3 groups consisting of patients who received Magnesium Sulfate 30 mg/Kg, Lidocaine 1.5 mg/Kg, and Control. These groups will be checked for hemodynamic changes and cortisol values.
- Trial name
- NCT06516861
- Testing
- Magnesium Sulfate 20 MG/ML, Lidocaine IV, saline solution
- Where
- Indonesia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Arsil Radiansyah
Bronchiolitis, Viral
Efficacy of Magnesium Sulfate Bolus in Pediatric Patients With Bronchiolitis
The purpose of this study is to more rigorously evaluate the response to a single bolus of magnesium sulfate in a population of patients with moderate to severe bronchiolitis.
- Trial name
- NCT04740294
- Testing
- Magnesium Sulfate
- Where
- United States
- Sponsor
- University of Louisville