Clinical trials: Magnesium Sulphate
Alagille Syndrome, Cholestasis
Study of Magnesium Sulfate in Children With Reduced Bone Density Secondary to Chronic Cholestatic Liver Disease
OBJECTIVES: I. Determine the role of magnesium deficiency in the pathogenesis of decreased serum vitamin D and reduced bone density in children with chronic cholestatic liver disease.
- Conditions
- Alagille Syndrome, Cholestasis, Biliary Atresia
- Trial name
- NCT00007033
- Testing
- magnesium gluconate, magnesium sulfate
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- National Center for Research Resources (NCRR)
Refractory Chronic Cluster Headache
Ketamine + Magnesium for Chronic Cluster Headache (KETALGIA)
Chronic cluster headache (CCH) is a rare primary headache disorder, defined by episodic attacks that occur for more than one year with no remission period or with remission periods lasting < 3 months (ICHD-3 criteria).
- Trial name
- KETALGIA (NCT04814381)
- Testing
- Ketamine + Magnesium sulfate (drug combination)
- Where
- 14 sites in France
- Volunteers
- 93 people
- Sponsor
- University Hospital, Clermont-Ferrand
Cancer, Breast
Magnesium Sulphate Versus Ketamine as an Adjuvant to Bupivacaine in Pectoral Nerve Block During Mastectomy
There are no published article that compare magnesium sulfate and ketamine as adjuvants to bupivacaine in PECS block , so the aim of this study is to evaluate the efficacy of Magnesium sulfate versus ketamine when added to local…
- Trial name
- NCT05663801
- Testing
- Use of Bupivacaine in pectoral nerve block in mastectomy, use of Ketamine as adjuvants to bupivacaine in pectoral nerve block in mastectomy, Use of Magnesium Sulfate as adjuvants to bupivacaine in pectoral nerve block in mastectomy
- Where
- Egypt
- Volunteers
- 72 people
- Sponsor
- Beni-Suef University
Spermatic Cord Block
Magnesium Sulfate in Combination With Dexmedetomidine As Adjuvants to Levobupivacaine
Using the spermatic cord block has been of great advantage, as it has been cost saving, efficient technique whether used inon its own or combination with a sedative or .
- Trial name
- NCT04498351
- Testing
- Control Test, Dexmedetomidine, Dexmedetomidine and magnesium sulphate
- Where
- Egypt
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Cairo University
Labor, Premature
Magnesium Sulfate Versus Indomethacin for Preterm Labor
The purpose of this study is to investigate the efficacy of Indomethacin compared to Magnesium Sulfate (MgSO4) in reducing neonatal morbidity through a prospective double blind randomized clinical trial.
- Trial name
- NCT00116623
- Testing
- Indomethacin, Magnesium sulfate
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Analgesia, Breast Cancer
Ketamine Versus Magnesium Sulphate as Adjuvants for ESPB in Breast Cancer Surgery
Our aim will be to compare the analgesic efficacy and safety of ketamine and magnesium sulphate as adjuvants to levobupivacaine in erector spinae plane block in modified radical mastectomy.
- Trial name
- NCT04275661
- Testing
- Ultrasound (US) bi-level erector spinae block, levobupivacaine, Ketamine
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Postoperative Pain
Magnesium Sulfate for TAP Analgesia During Laparoscopic Cholecystectomy
Study the effect of adding Magnesium sulfate to TAP block in analgesia after laparoscopic cholecystectomy.
- Trial name
- NCT02533284
- Testing
- Magnesium Sulfate, bupevecaine, saline
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Mansoura University
Smooth Extubation
Smooth Extubation With Magnesium Sulphate for General Anesthesia With Endotracheal Intubation
Tracheal extubation is a critical event in the anaesthetic management of patients undergoing general anaesthesia with endotracheal intubation for elective procedures.
- Trial name
- NCT04617652
- Testing
- Magnesium sulfate, Normal saline
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Fayoum University Hospital
Asthma in Children, Asthma Attack
Timely Administration of IV Magnesium Sulfate in Patients With a Moderate Asthma Exacerbation
This study aims to identify whether early administration of magnesium sulfate in moderate asthma exacerbations can potentially avoid admission, decrease length of stay in the emergency department (ED), decrease length of stay…
- Trial name
- NCT06137040
- Testing
- Magnesium Sulfate within the first hour, No Magnesium sulfate within the first hour
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Oklahoma
Atrial Fibrillation (AF), Magnesium Sulfate
Evaluation of the Role of Magnesium in Prevention of AF Post Cardiac Surgery
Atrial fibrillation (AF) is a common complication after cardiac surgery. Most studies suggest that the frequency ranges between 25-40%.
- Conditions
- Atrial Fibrillation (AF), Magnesium Sulfate, Post Cardiac Surgery Patients
- Trial name
- Magnesium AF (NCT06675500)
- Testing
- Magnesium sulphate
- Where
- Egypt
- Volunteers
- 130 people
- Sponsor
- Ain Shams University
Hemodynamic Response to Laryngoscopy and Tracheal Intubation
Intravenous Magnesium Sulphate Versus Lignocaine for Attenuating Hemodynamic Responses to Laryngoscopy and Endotracheal Intubation
This study will compare intravenous magnesium sulfate with intravenous lidocaine for reducing the cardiovascular response to endotracheal intubation in adult patients undergoing general anesthesia.
- Trial name
- NCT07793955
- Testing
- Magnesium Sulphate infusion
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Lady Reading Hospital, Pakistan
Preeclampsia
Different Schemes of Magnesium Sulfate for Preeclampsia
Eclampsia is an obstetric emergency capable of prophylaxis. To prevent and control seizures, there is no doubt that the magnesium sulfate (MgSO4) is the ideal drug. However, there are still questions regarding its use and dose.
- Trial name
- MGSO4 (NCT02396030)
- Testing
- Magnesium sulfate 50% - 1g/h, Magnesium sulfate 50% - 2g/h
- Where
- Brazil
- Volunteers
- 62 people
- Sponsor
- Instituto Materno Infantil Prof. Fernando Figueira
Hypertension, Tachycardia
Comparison of Fentanyl and Magnesium to Control Reflex Hemodynamics in Patients Aged 50 and Older
This prospective, randomized, controlled trial aims to evaluate the effects of magnesium sulfate and fentanyl on the hemodynamic response to endotracheal intubation in surgical patients aged 50 years and older.
- Trial name
- NCT07258628
- Testing
- magnesium sulfate, Fentanyl (IV)
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 76 people
- Sponsor
- Ankara City Hospital Bilkent
Pain
Magnesium Sulphate in the Ultrasound-guided Supraclavicular Brachial Plexus Block
This study evaluated the motor and sensory block duration and the postoperative analgesic effects of adding Magnesium Sulphate to bupivacaine in the ultrasound-guided supraclavicular brachial plexus block Anesthesia.
- Trial name
- Mg (NCT02752334)
- Testing
- Magnesium Sulphate
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Magrabi Eye & Ear Hospital
Preeclampsia
Adding MgSO4 to Epidural Levobupivacaine in CS for Patients With Preeclampsia
This study aims at evaluating the effect of adding magnesium sulphate epidurally as an adjunct to levobupivacaine on the quality of anesthesia and perioperative pain relief in patients with preeclampsia undergoing elective…
- Trial name
- NCT02699827
- Testing
- Levobupivacaine hydrochloride, Magnesium sulphate, Saline 0.9%
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Mohamed Sayed Abdelhafez
Asthma in Children
Magnesium Sulfate in Bronchial Asthma and Acute Bronchiolitis in Children
Asthma is a prevalent disease that affects as many as334 million individuals worldwide, and is a major source of disability and premature death in children(1). Asthma affects 7.1 million children in the United States (2).
- Trial name
- NCT06955559
- Testing
- Magnesium sulfate
- Volunteers
- 60 people
- Sponsor
- Assiut University
Benign Prostatic Hyperplasia Postoperative Pain
Comparison of Magnesium Sulphate vs Tramadol as Adjuvants in Intrathecal Bupivacaine for Postoperative Pain in TURP Patients
The goal of this clinical trial is to determine whether adding magnesium sulfate or tramadol to intrathecal bupivacaine improves postoperative pain control and hemodynamic stability in adult male patients undergoing transurethral…
- Trial name
- NCT07113782
- Testing
- 1. Magnesium Sulphate 2. Tramadol
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Armed Forces Institute of Urology, Rawalpindi
Increased Intra Ocular Pressure (IOP)
The Effect of Intravenous Magnesium Sulfate on Intraocular Pressure Following Tracheal Intubation
The aim of this study is to assess the effect of preoperatively administered intra venous magnesium sulfate in attenuating pressure response to laryngoscopy and endotracheal intubation in adult patients scheduled for elective non…
- Trial name
- NCT01241175
- Testing
- Magnesium Sulfate, normal saline
- Where
- Iran
- Sponsor
- Shiraz University of Medical Sciences
Neuromuscular Blockade
The Effect of Magnesium Sulphate on the Time Course of Rocuronium Induced Neuromuscular Block
The aim of this study is to investigate whether an optimized pre-treatment with intravenous magnesium enhances the speed of onset of a standard intubation dose of rocuronium.
- Trial name
- MagRoc (NCT00405977)
- Testing
- Physiologic saline, Magnesium sulphate
- Where
- Switzerland
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University Hospital, Geneva
Temporomandibular Joint Arthralgia, Temporomandibular Joint Disc Displacement
Magnesium Sulfate After TMJ Arthrocentesis
Temporomandibular joint (TMJ) arthrocentesis is a well-established minimally invasive treatment for patients with TMJ arthralgia and internal derangement.
- Trial name
- MAGART (NCT07745660)
- Testing
- Magnesium Sulfate Group → Experimental, Hyaluronic Acid (HA), Normal Saline (0.9% Sodium Chloride)
- Where
- Turkey (Türkiye)
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Yuzuncu Yil University